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| 1 | 中西医医学生在叙事医学上的不同视野显示文摘医学作为一种实践科学还是治疗艺术,在现在的医学界有广泛的争论。很多人认为,医学必须要求医生在自身建立叙事情感并且更深入地挖掘病人的内心。文中的调查研究活动以台湾某教学医院的学生为研究对象,开展叙事医学项目的系列活动,采用问卷调查和量表研究,并评估和比较了中西医学生对于叙事医学作为一种学习共情和医学专业精神的方法的不同认知。 | 张千会 周碧雯 Chien - Da Huang Kuo - Chen Liao Fu - Tsai Chuang | 2017 | 中国医学伦理学2017，30，10： | 14 |
| 2 | Effect of an electrostatic field on gas adsorption and diffusion in tectonic coal显示文摘The characteristics of adsorption, desorption, and diffusion of gas in tectonic coal are important for the prediction of coal and gas outbursts. Three types of coal samples, of which both metamorphic grade and degree of damage is different, were selected from Tongchun, Qilin, and Pingdingshan mines. Using a series of experiments in an electrostatic field, we analyzed the characteristics of gas adsorption and diffusion in tectonic coal. We found that gas adsorption in coal conforms to the Langmuir equation in an electrostatic field. Both the depth of the adsorption potential well and the coal molecular electronegativity increases under the action of an electrostatic field. A Joule heating effect was caused by changing the coal–gas system conductivity in an electrostatic field. The quantity of gas adsorbed and DP result from competition between the depth of the adsorption potential well, the coal molecular electronegativity, and the Joule heating effect. DP peaks when the three factors control behavior equally. Compared with anthracite, the impact of the electrostatic field on the gas diffusion capacity of middle and high rank coals is greater. Compared with the original coal, the gas adsorption quantity, DP, and the gas diffusion capacity of tectonic coal are greater in an electrostatic field. In addition, the smaller the particle size of tectonic coal, the larger the DP. | Jian Kuo Lei Dongji Fu Xuehai Zhang Yugui Li Hengle | 2015 | International Journal of Mining Science and Technology2015，25，4： | 4 |
| 3 | The role of MAPK and FAS death receptor pathways in testicular germ cell apoptosis induced by lead显示文摘现在的学习的目的是调查在阴囊的细菌房间的导致铅的 apoptosis 涉及 MAPK 的信号小径和船边交货的死亡信号受体小径的基因表示。首先,房间生存能力被 MTT 试金决定。第二,使用单个房间胶化电气泳动测试(彗星试金) 和染色技术, apoptotic 率和阴囊的细菌房间的房间 apoptosis 本地化的 TUNEL 在分别地与 0.15% , 0.3% ,和 0.6% 铅一起对待的老鼠被测量。第三, K 地岬, c-fos,船边交货,和活跃 caspase-3 蛋白质的 immunolocalization 被 immunohistochemistry 决定。最后,在 K 地岬, c-fos,船边交货,和活跃 caspase-3 的翻译层次的变化被西方的污点分析进一步检测。我们的结果证明铅能显著地以一种剂量依赖者方式导致阴囊的细菌房间 apoptosis (P < 0.01 ) 。机制是仔细与在 apoptotic 细菌房间的 K 地岬, c-fos,船边交货,和活跃 caspase-3 的增加的表情有关。在结论, K-ras/c-fos 和 Fas/caspase-3 死亡发信号受体小径在老鼠涉及阴囊的细菌房间的导致铅的 apoptosis。 | Shuying Dong Duoping Liang Na An Li Jia Yujuan Shan Chao Chen Kuo Sun Fei Niu Huiyan Li Songbin Fu | 2009 | Acta Biochimica et Biophysica Sinica2009，41，9： | 4 |
| 4 | H elicobacter pylori infection associated with high H b A 1c and type 2 diabetes显示文摘 | Ming‐Chia Hsieh Sophie S. W. Wang Yi‐Ting Hsieh Fu‐Chen Kuo Maw‐Soan Soon Deng‐Chyang Wu | 2013 | Eur J Clin Invest2013，，9： | 4 |
| 5 | 经自然腔道取标本手术(NOSES)治疗结直肠癌的国际共识显示文摘近年来,经自然腔道取标本手术(NOSES)治疗结直肠癌已引起了广泛关注。NOSES应用于结直肠手术的潜在优势包括减轻术后疼痛,减少伤口并发症,减少对术后镇痛的需求,加快肠道功能的恢复,缩短住院时间,更好的美容效果,以及给患者带来了更佳的心理状态。尽管NOSES的手术创伤显著减轻,然而该技术也存在一些潜在问题。尤其随着这项新技术的兴起,人们对其无菌的把控、肿瘤学结果和病例选择等问题表示出关切。因此,迫切需要一部操作指南来规范NOSES手术在结直肠癌中的开展。经过国际NOSES联盟全体成员的三轮讨论,最终形成了该部共识。这一共识有助于NOSES在全球范围内的长远发展。 | Xu Guan Zheng Liu Antonio Longo Jian-Chun Cai William Tzu-Liang Chen Lu-Chuan Chen Ho-Kyung Chun Joaquim Manuel da Costa Pereira Sergey Efetov Ricardo Escalante Qing-Si He Jun-Hong Hu Cuneyt Kayaalp Seon-Hahn Kim Jim S.Khan Li-Jen Kuo Atsushi Nishimura Fernanda Nogueira Junji Okuda Avanish Saklani Ali A.Shafik Ming-Yin Shen Jung-Tack Son Jun-Min Song Dong-Hui Sun Keisuke Uehara Gui-Yu Wang Ye Wei Zhi-Guo Xiong Hong-Liang Yao Gang Yu Shao-Jun Yu Hai-Tao Zhou Suk-Hwan Lee Petr V.Tsarkov Chuan-Gang Fu Xi-Shan Wang The International Alliance of NOSES | 2019 | Gastroenterology Report2019，7，1： | 3 |
| 6 | Low effect‐site concentration of propofol target‐controlled infusion reduces the risk of hypotension during endoscopy in a T aiwanese population显示文摘 | Wen‐Hung Hsu Sophie SW Wang Hsiang‐Yao Shih Meng‐Chieh Wu Yi‐Yu Chen Fu‐Chen Kuo Hui‐Ying Yang Shun‐Li Chiu Koung‐Shing Chu Kuang‐I Cheng Deng‐Chyang Wu I‐Cheng Lu | 2013 | Journal of Digestive Diseases2013，，3： | 3 |
| 7 | Sparing lung tissue with virtual block method in VMAT planning for locally advanced non-small cell lung cancer显示文摘This study aimed to exploit a new virtual block method to spare normal lung tissue in VMAT planning for patients with locally advanced non-small cell lung cancer(LA-NSCLC).The previous method was used to manually restrict the angle of the beam passing through,which ignored the location and shape of large targets that varied between different slices and did not block the beamlets precisely.Unlike the previous method,this new virtual block method was used to block the beamlets when necessary by closing the multi-leaf collimator(MLC)at prerequisite angles.The algorithm for closing the MLC depended on the thickness of the beamlets passing through the lungs and avoided only the entrance radiation beamlet.Moreover,this block can be automatically contoured.A retrospective study was performed to compare the VMAT plans with and without the virtual block method for 17 LANSCLC patients,named the block plan(B-plan)/non-block plan(N-plan).All cases were selected in this study because of the large tumor size and unmet dose constraints of the lungs.In addition to the maximum dose constraint for the virtual block,B-plans adopted identical optimization parameters to N-plans for each patient.These two types of plans were compared in terms of dosimetric indices and plan scores.The results were statistically analyzed using the Wilcoxon nonparametric signed-rank test.B-plans have advantages in the following dosimetric metrics that have statistical significance(p<0.05):(1)lower V_(5)/V_(10)/D_(mean)/normal tissue complication probability(NTCP)of total lungs;(2)reductions in V_(5)/V_(10)for the contralateral lung;(3)decrease in Dmean/V_(40)of the heart;(4)decrease in esophagus V_(40);(5)reductions in Dmean,V_(5)/V_(10) of normal tissue.B-plans(82.51±7.07)achieved higher-quality scores than N-plans(80.74±7.22).The new virtual block spared the lungs as well as other normal structures in VMAT planning for LA-NSCLC.Thus,the block method may decrease the risk of radiation-related toxicity in patients. | Jia-Yun Chen Da-Quan Wang Xiao-Dong Zhang Qi Fu Xue-Na Yan Kuo Men Jian-Rong Dai Nan Bi | 2022 | Nuclear Science and Techniques2022，33，4： | 3 |
| 8 | Plasma metabolomics combined with personalized diagnosis guided by Chinese medicine reveals subtypes of chronic heart failure显示文摘Background:Chronic heart failure(CHF)is characterized by insufficient blood supply from heart to meet the body’s metabolic demands.Integrating Western and traditional Chinese medicine to treat CHF has proved a validated therapeutic approach.In recent years,metabolomics has been regarded as a potential platform to provide biomarkers for diseasesubtypes.Objective:To examine 38 patients,combined NMR plasma metabolomics and traditional Chinese medicine diagnosis in order to identify diagnostic biomarkers for two CHF syndrome subtypes.Methods:After processing the spectra,orthogonal partial least square discriminant analysis was performed,and the contributing NMR signals were analyzed using Y-scrambling statistical validation with good reliability.Results:Plasma metabolic patterns of yin deficiency and yang deficiency patients were clearly discriminated.The yin-deficiency group had increased level of lactate,glycoprotein,lipoprotein and lower levels of glucose,valine and proline.The yang-deficiency group had higher levels of lactate,glycoprotein and pyruvic acid,and lower levels of glucose and lipoprotein.Potential biomarkers of CHF based on the two traditional Chinese medicine syndromes indicated alternative modes of metabolites and metabolic pathways in the disease,e.g.dysfunction of energy utilization and disturbance in fatty acids,amino acids.Conclusion:This study suggests that combining metabolomics with traditional Chinese medicine diagnosis can reveal metabolic signatures for CHF syndrome subtypes.The plasma metabolites identified might be of special clinical relevance for subtypes of CHF,which could lead to further understanding of mechanisms involved and an improvement in personalized treatment for CHF. | Juan Wang Shuzhen Guo Kuo Gao Qi Shi Bangze Fu Chan Chen Liangtao Luo Dong Deng Huihui Zhao Wei Wang | 2015 | Journal of Traditional Chinese Medical Sciences2015，2，2： | 2 |
| 9 | Gasless laparoscopic assisted surgery for abdominal trauma显示文摘 | Liao CH Kuo IM Fu CY | 2013 | Injury2013，45，5： | 1 |
| 10 | Evaluation of the antibacterial efficacy of bamboo charcoal/silver biological protective material 显示文摘 | FU Chu Yanga KUO Hui Wua MING Jie Liua | 2009 | Materials Chemistry and Physics2009，，113： | 1 |
| 11 | Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes显示文摘 | You-Cheng Hseu Chih-Wei Chou K.J. Senthil Kumar Ke-Ting Fu Hui-Min Wang Li-Sung Hsu Yueh-Hsiung Kuo Chi-Rei Wu Ssu-Ching Chen Hsin-Ling Yang | 2012 | Food and Chemical Toxicology2012，，5： | 1 |
| 12 | The numbers of fungi:contributions from traditional taxonomic studies and challenges of metabarcoding显示文摘The global diversity of fungi has been estimated using several different approaches.There is somewhere between 2–11 million estimated species,but the number of formally described taxa is around 150,000,a tiny fraction of the total.In this paper,we examine 12 ascomycete genera as case studies to establish trends in fungal species descriptions,and introduce new species in each genus.To highlight the importance of traditional morpho-molecular methods in publishing new species,we introduce novel taxa in 12 genera that are considered to have low species discovery.We discuss whether the species are likely to be rare or due to a lack of extensive sampling and classification.The genera are Apiospora,Bambusicola,Beltrania,Capronia,Distoseptispora,Endocalyx,Neocatenulostroma,Neodeightonia,Paraconiothyrium,Peroneutypa,Phaeoacremonium and Vanakripa.We discuss host-specificity in selected genera and compare the number of species epithets in each genus with the number of ITS(barcode)sequences deposited in GenBank and UNITE.We furthermore discuss the relationship between the divergence times of these genera with those of their hosts.We hypothesize whether there might be more species in these genera and discuss hosts and habitats that should be investigated for novel species discovery. | Chayanard Phukhamsakda Rolf Henrik Nilsson Chitrabhanu S.Bhunjun Antonio Roberto Gomes de Farias Ya-Ru Sun Subodini N.Wijesinghe Mubashar Raza Dan-Feng Bao Li Lu Saowaluck Tibpromma Wei Dong Danushka S.Tennakoon Xing-Guo Tian Yin-Ru Xiong Samantha C.Karunarathna Lei Cai Zong-Long Luo Yong Wang Ishara S.Manawasinghe Erio Camporesi Paul M.Kirk Itthayakorn Promputtha Chang-Hsin Kuo Hong-Yan Su Mingkwan Doilom Yu Li Yong-Ping Fu Kevin D.Hyde | 2022 | Fungal Diversity2022，，3： | 1 |
| 13 | Effect of acid on the mycelial growth and polysaccharide formation by Ganoderma lucidum in shake flask culture显示文摘 | Fan Chiang Yang Yn Fu Ke Shang Shin Kuo | 2000 | Enzyme and microbial technology2000，27，4： | 1 |
| 14 | OBDD-based network reliability calculation显示文摘 | FU MIN YEH SY YEN KUO | 1997 | Electronics Letters1997，33，9： | 1 |
| 15 | Determining terminal-pair network reliability based on edge expansion diagrams using OBDD 显示文摘 | SY YEN KUO SHYUE KUNG LU FU MIN YEH | 1999 | IEEE Trans- actions on Reliability1999，48，3： | 1 |
| 16 | OBDD-based evaluation of k-terminal network reliability 显示文摘 | FU MIN YEH SHYUE KUNG LU SY YEN KUO | 2002 | IEEE Transactions on Reliability2002，51，4： | 1 |
| 17 | Gasless laparoscopic assisted surgery for abdominal trauma显示文摘 | Liao CH Kuo IM Fu CY | 2014 | Injury2014，45，5： | 1 |
| 18 | Adaptive Robust Bank-to-turn Design Using Neural Networks 显示文摘 | Fu L C Chang W D Yang J H Kuo T | 1997 | Journal of Guidance Control and Dynamics1997，20，2： | 1 |
| 19 | Long-tern1 follow-up of spinal and bulbar muscular atrophy in Taiwan显示文摘 | Fu S Kuo H Chu C | 2013 | Journal of the Formosan Medical Association2013，112，6： | 1 |
| 20 | Non-linear Dynamics of Inlet Film Thickness during Unsteady Rolling Process显示文摘The inlet film thickness directly affects film and stress distribution of rolling interfaces. Unsteady factors, such as unsteady back tension, may disturb the inlet film thickness. However, the current models of unsteady inlet film thickness lack unsteady disturbance factors and do not take surface topography into consideration. In this paper, based on the hydrodynamic analysis of inlet zone an unsteady rolling film model which concerns the direction of surface topography is built up. Considering the small fluctuation of inlet angle, absolute reduction, reduction ratio, inlet strip thickness and roll radius as the input variables and the fluctuation of inlet film thickness as the output variable, the non-linear relationship between the input and output is discussed. The discussion results show that there is 180° phase difference between the inlet film thickness and the input variables, such as the fluctuant absolute reduction, the fluctuant reduction ratio and non-uniform inlet strip thickness, but there is no phase difference between unsteady roll radius and the output. The inlet angle, the steady roll radius and the direction of surface topography have significant influence on the fluctuant amplitude of unsteady inlet film thickness. This study proposes an analysis method for unsteady inlet film thickness which takes surface topography and new disturbance factors into consideration. | FU Kuo ZANG Yong GAO Zhiying QIN Qin WU Diping | 2016 | Chinese Journal of Mechanical Engineering2016，29，3： | 1 |
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