|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A matched-pair analysis of laparoscopic versus open pancreaticoduodenectomy: oncological outcomes using Leeds Pathology Protocol显示文摘BACKGROUND: Laparoscopic pancreaticoduodenectomy(LPD)is a safe procedure. Oncological safety of LPD is still a matter for debate. This study aimed to compare the oncological outcomes,in terms of adequacy of resection and recurrence rate following LPD and open pancreaticoduodenectomy(OPD).METHODS: Between November 2005 and April 2009, 12LPDs(9 ampullary and 3 distal common bile duct tumors)were performed. A cohort of 12 OPDs were matched for age,gender, body mass index(BMI) and American Society of Anesthesiologists(ASA) score and tumor site.RESULTS: Mean tumor size LPD vs OPD(19.8 vs 19.2 mm,P=0.870). R0 resection was achieved in 9 LPD vs 8 OPD(P=1.000). The mean number of metastatic lymph nodes and total number resected for LPD vs OPD were 1.1 vs 2.1(P=0.140)and 20.7 vs 18.5(P=0.534) respectively. Clavien complications grade I/II(5 vs 8), III/IV(2 vs 6) and pancreatic leak(2 vs 1)were statistically not significant(LPD vs OPD). The mean high dependency unit(HDU) stay was longer in OPD(3.7 vs 1.4 days,P<0.001). There were 2 recurrences each in LPD and OPD(logrank,P=0.983). Overall mortality for LPD vs OPD was 3 vs 6(log-rank, P=0.283) and recurrence-related mortality was 2 vs 1.There was one death within 30 days in the OPD group secondary to severe sepsis and none in the LPD group.CONCLUSIONS: Compared to open procedure, LPD achieved a similar rate of R0 resection, lymph node harvest and longterm recurrence for tumors less than 2 cm. Though technically challenging, LPD is safe and does not compromise oncological outcome. | Abdul R Hakeem Caroline S Verbeke Alison Cairns Amer Aldouri Andrew M Smith Krishna V Menon | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，4： | 24 |
| 2 | Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany显示文摘AIM:To study the epidemiologic changes of gastroenteropancreatic neuroendocrine tumors(GEP-NET)in Germany,we analyzed two time periods 1976-1988 and1998-2006.METHODS:We evaluated epidemiological data of GEP-NET from the former East German National Cancer Registry(DDR Krebsregister,1976-1988)and its successor,the Joint Cancer Registry(GKR,1998-2006),which was founded after German reunification.Due to a particularly substantial database the epidemiological data from the federal states of Mecklenburg-Western Pomerania,Saxony,Brandenburg and Thuringia,covering a population of more than 10.8 million people,were analyzed.Survival probabilities were calculated using life table analysis.In addition,GEP-NET patients were evaluated for one or more second(non-GEP-NET)primary malignancies.RESULTS:A total of 2821 GEP neuroendocrine neoplasms were identified in the two registries.The overall incidence increased significantly between 1976 and2006 from 0.31(per 100.000 inhabitants per year)to2.27 for men and from 0.57 to 2.38 for women.In the later period studied(2004-2006),the small intestine was the most common site.Neuroendocrine(NE)neoplasms of the small intestine showed the largest absolute increase in incidence,while rectal NE neoplasms exhibited the greatest relative increase.Only the incidence of appendiceal NET in women showed little change between 1976 and 2006.Overall survival of patients varied for sex,tumor site and the two periods studied but improved significantly over time.Interestingly,about 20%of the GEP-NET patients developed one or more second malignancies.Their most common location was the gastrointestinal tract.GEP-NET patients without second malignancies fared better than those with one or more of them.CONCLUSION:The number of detected GEP-NET increased about 5-fold in Germany between 1976 and2006.At the same time,their anatomic distribution changed,and the survival of GEP-NET patients improved significantly.Second malignancies are common and influence the overall survival of GEP-NET patients.Thus,GEP-NET warrant our attention as well as intensive research on their tumorigenesis. | Hans Scherübl Brigitte Streller Roland Stabenow Hermann Herbst Michael Hopfner Christoph Schwertner Joachim Steinberg Jan Eick Wanda Ring Krishna Tiwari Soren M Zappe | 2013 | World Journal of Gastroenterology2013，19，47： | 16 |
| 3 | Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘 | Paul M Healy Krishna G Palepu | 2001 | Journal of Accounting and Economics2001，，1： | 14 |
| 4 | Software for automated classification of probe-based confocal laser endomicroscopy videos of colorectal polyps显示文摘AIM:To support probe-based confocal laser endomi-croscopy (pCLE) diagnosis by designing software for the automated classification of colonic polyps. METHODS:Intravenous fluorescein pCLE imaging of colorectal lesions was performed on patients under-going screening and surveillance colonoscopies, followed by polypectomies. All resected specimens were reviewed by a reference gastrointestinal pathologist blinded to pCLE information. Histopathology was used as the criterion standard for the differentiation between neoplastic and non-neoplastic lesions. The pCLE video sequences, recorded for each polyp, were analyzed off-line by 2 expert endoscopists who were blinded to the endoscopic characteristics and histopathology. These pCLE videos, along with their histopathology diagnosis, were used to train the automated classification software which is a content-based image retrieval technique followed by k-nearest neighbor classification. The performance of the off-line diagnosis of pCLE videos established by the 2 expert endoscopists was compared with that of automated pCLE software classification. All evaluations were performed using leave-one-patient- out cross-validation to avoid bias. RESULTS:Colorectal lesions (135) were imaged in 71 patients. Based on histopathology, 93 of these 135 lesions were neoplastic and 42 were non-neoplastic. The study found no statistical significance for the difference between the performance of automated pCLE software classification (accuracy 89.6%, sensitivity 92.5%, specificity 83.3%, using leave-one-patient-out cross-validation) and the performance of the off-line diagnosis of pCLE videos established by the 2 expert endoscopists (accuracy 89.6%, sensitivity 91.4%, specificity 85.7%). There was very low power (< 6%) to detect the observed differences. The 95% confidence intervals for equivalence testing were:-0.073 to 0.073 for accuracy, -0.068 to 0.089 for sensitivity and -0.18 to 0.13 for specificity. The classification software proposed in this study is not a 'black box' but an informative tool based on the query by example model that produces, as intermediate results, visually similar annotated videos that are directly interpretable by the endoscopist. CONCLUSION:The proposed software for automated classification of pCLE videos of colonic polyps achieves high performance, comparable to that of off-line diagnosis of pCLE videos established by expert endoscopists. | Barbara André Tom Vercauteren Anna M Buchner Murli Krishna Nicholas Ayache Michael B Wallace | 2012 | World Journal of Gastroenterology2012，18，39： | 5 |
| 5 | Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘 | Paul M Healy Krishna G Palepu | 2001 | Journal of Accounting and Economics2001，，1： | 4 |
| 6 | Effect of temperature on storage polymers and settleability of activated sludge显示文摘 | Chundakkadu Krishna Mark C M Van Loosdrecht | 1999 | Wat Res1999，33，10： | 2 |
| 7 | Trends and outcomes of transarterial chemoembolization in hepatocellular carcinoma:a national survey显示文摘BACKGROUND:Transarterial chemoembolization(TACE) is a palliative procedure frequently used in patients with advanced hepatocellular carcinoma(HCC). We examined the national inpatient trends of TACE and related outcomes in the United States over the last decade.METHODS:We utilized the National Inpatient Sample(2002 to 2012) and performed trend analyses of TACE for HCC in all adult patients(age >18 years). Multivariate analyses for the outcomes of in-hospital 'procedure-related complications'(PRCs) and 'post-procedure complications'(PPCs) were performed. We also compared early(2002 to 2006) and late(2007 to 2012) eras by multivariate analyses to identify predictors of complications, healthcare resource utilization and mortality.RESULTS:Overall, 19058 patients underwent TACE for HCC where PRCs and PPCs were seen in 24.2% and 17.6% of patients, respectively. The overall trends in the use of TACE(P<0.001) and associated PRCs(P=0.006) were observed to be increasing. There was less mortality [adjusted Odds ratio(a OR):0.58; 95% CI:0.41, 0.82], reduced length of hospital stay(-1.87 days; 95% CI:-2.77,-0.97) and increased hospital charges($19232; 95% CI:11013, 27451) in the late era. Additionally, there was increased mortality(a OR:4.07; 95% CI:2.96, 5.59), PRCs(a OR:3.21; 95% CI:2.56, 4.02), and PPCs(a OR:2.70; 95% CI:2.11, 3.46) among patients with coagulopathy.CONCLUSIONS:There is an increasing trend of TACE utilization in HCC. However, the outcomes are worse in patients with coagulopathy. Although PRCs have increased, mortality has decreased in recent years. These findings should be considered during TACE evaluation in patients with HCC. | Khalid Mumtaz Nishi Patel Rohan M Modi Vihang Patel Alice Hinton James Hanje Sylvester M Black Somashaker Krishna | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，6： | 2 |
| 8 | Driveline load analysis with multiple cardan joints 显示文摘 | Krishna V Peelamedu S M Phadnis R | 2000 | JSME Int J Ser C2000，43，3： | 2 |
| 9 | Genetic K-means Algorithm显示文摘 | Krishna K Narasimha M M | 1999 | IEEE Transactions on Systems Man and Cybernetics-Part B : Cybernetics1999，29，3： | 1 |
| 10 | Scheduled dataflow execution paradigm architecture, and performance evaluation 显示文摘 | Krishna M K Roberto Giorgi Joseph Arul | 2001 | IEEE Transactions on Computers2001，50，8： | 1 |
| 11 | An improved maximum power point tracker using a step-up converter with current locked loop显示文摘 | Maheshappa H D Nagaraju J Krishna Murthy M V | 1998 | Renewable Energy1998，13，2： | 1 |
| 12 | Cement leakage in percutaneous vertebroplasty:effect of preinjection gelfoam embolization显示文摘 | Bhatia C Barzilay Y Krishna M | 2006 | Spine (Phila Pa 1976)2006，31，8： | 1 |
| 13 | Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation显示文摘 | Seibenhener M L Babu J R Geetha T Wong H C Krishna N R Wooten M W | | 0，，18： | 1 |
| 14 | Analysis of tree-based multicast routing in wireless sensor networks with varying network metrics显示文摘 | Krishna M Doja M | 2013 | International Journal of Communication Systems2013，26，10： | 1 |
| 15 | Antimicrobial activity and protease stability of peptides containing fluorinated amino acids显示文摘 | He M Krishna K | 2008 | JACS2008，129，15： | 1 |
| 16 | Ion Exchange Properties of Strontium on in Situ Precipitated Polyantimonic Acid in Amberlite XAD- 7显示文摘 | Sivaiah M V Venkatesan K A Krishna R M | 2005 | Sep Purif Technol2005，44，5： | 1 |
| 17 | Per- vaporation separation of water+1,4-dioxane and water+ tetrahydrofuran mixtures using sodium alginate and its blend membranes with hydroxyethylcellulose :A com- parative study显示文摘 | Naidu B V K Krishna R K S V Aminabhavi T M | 2005 | Journal of Membrane Science2005，260，12： | 1 |
| 18 | Influence of alcohol addition on gas hold-up in bubble columns: development of a scale up model 显示文摘 | KRISHNA R DREHER A J URSEANU M I | 2000 | Int Commun Heat Mass Transf2000，27，4： | 1 |
| 19 | Filamentous bulking sludge-a critical review显示文摘 | ANTONIO M KRISHNA P JOSEPH H | 2004 | Wat Res2004，38，4： | 1 |
| 20 | Geochemical systematics of komatiite-tholeiite and adakite-arc basalt associations:the role of a mantle plume and convergent margin in formation of the Sandur Superterrane,Dharwar Craton,India显示文摘 | Manikyamba C Kerrich R Khanna T.C Krishna A.K Satyanarayanan M | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员