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| 1 | A matched-pair analysis of laparoscopic versus open pancreaticoduodenectomy: oncological outcomes using Leeds Pathology Protocol显示文摘BACKGROUND: Laparoscopic pancreaticoduodenectomy(LPD)is a safe procedure. Oncological safety of LPD is still a matter for debate. This study aimed to compare the oncological outcomes,in terms of adequacy of resection and recurrence rate following LPD and open pancreaticoduodenectomy(OPD).METHODS: Between November 2005 and April 2009, 12LPDs(9 ampullary and 3 distal common bile duct tumors)were performed. A cohort of 12 OPDs were matched for age,gender, body mass index(BMI) and American Society of Anesthesiologists(ASA) score and tumor site.RESULTS: Mean tumor size LPD vs OPD(19.8 vs 19.2 mm,P=0.870). R0 resection was achieved in 9 LPD vs 8 OPD(P=1.000). The mean number of metastatic lymph nodes and total number resected for LPD vs OPD were 1.1 vs 2.1(P=0.140)and 20.7 vs 18.5(P=0.534) respectively. Clavien complications grade I/II(5 vs 8), III/IV(2 vs 6) and pancreatic leak(2 vs 1)were statistically not significant(LPD vs OPD). The mean high dependency unit(HDU) stay was longer in OPD(3.7 vs 1.4 days,P<0.001). There were 2 recurrences each in LPD and OPD(logrank,P=0.983). Overall mortality for LPD vs OPD was 3 vs 6(log-rank, P=0.283) and recurrence-related mortality was 2 vs 1.There was one death within 30 days in the OPD group secondary to severe sepsis and none in the LPD group.CONCLUSIONS: Compared to open procedure, LPD achieved a similar rate of R0 resection, lymph node harvest and longterm recurrence for tumors less than 2 cm. Though technically challenging, LPD is safe and does not compromise oncological outcome. | Abdul R Hakeem Caroline S Verbeke Alison Cairns Amer Aldouri Andrew M Smith Krishna V Menon | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，4： | 24 |
| 2 | Hepatoprotective activity of Hepax-A polyherbal formulation显示文摘Objective:To evaluate the hepatoprotective potential of Hepax,a polyherbal formulation,against three experimentally induced hepatotoxicity models in rats.Methods:Hepatoprotective activity of Hepax was studied against three experimentally induced hepatotoxicity models,namely, carbon tetrachloride(CCl_4),paracetamol and thiocetamide induced hepatotoxicity in rats. Results:Administration of hepatotoxins(CCl_4,paracetamol and thiocetamide) showed significant morphological,biochemical and histological deteriorations in the liver of experimental animals. Pretreatment with Hepax had significant protection against hepatic damage by maintaining the morphological parameters(liver weight and liver weight to organ weight ratio) within normal range and normalizing the elevated levels of biochemical parameters(SGPT,SCOT,ALP and total bilirubin),which were evidently showed in histopathological study.Conclusions:The Hepax has highly significant hepatoprotective effect at 100 and 200 mg/kg,p.o.on the liver of all the three experimental animal models. | VC Devaraj B Gopala Krishna GL Viswanatha Jagadish V Kamath Sanjay Kumar | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 4 |
| 3 | Analysis of driveline loads in an automotive powertrain with multiple Cardan joints显示文摘 | Krishna V Naganathan N G Phaduis R | 2000 | Journal of Autombile Engineering2000，214，： | 2 |
| 4 | Driveline load analysis with multiple cardan joints 显示文摘 | Krishna V Peelamedu S M Phadnis R | 2000 | JSME Int J Ser C2000，43，3： | 2 |
| 5 | Analysis of driveline loads in an automotive power train with multiple Cardan joints 显示文摘 | Krishna V Naganathan N G Phadnis R | 2000 | Proc Inst Mech Eng Part D J Automob Eng2000，214，5： | 2 |
| 6 | Person-independent pose estimation using biased manifold embedding显示文摘 | Balasubramanian V N Krishna S Panchanathan S | 2008 | EURASIP Journal on Advances in Signal Processing2008，8，2： | 1 |
| 7 | An improved maximum power point tracker using a step-up converter with current locked loop显示文摘 | Maheshappa H D Nagaraju J Krishna Murthy M V | 1998 | Renewable Energy1998，13，2： | 1 |
| 8 | Estimation of origin- destination matrix from traffic counts: the state of the art显示文摘 | S Bera K V Krishna Rao | 2011 | European Transport2011，49，： | 1 |
| 9 | Ion Exchange Properties of Strontium on in Situ Precipitated Polyantimonic Acid in Amberlite XAD- 7显示文摘 | Sivaiah M V Venkatesan K A Krishna R M | 2005 | Sep Purif Technol2005，44，5： | 1 |
| 10 | Per- vaporation separation of water+1,4-dioxane and water+ tetrahydrofuran mixtures using sodium alginate and its blend membranes with hydroxyethylcellulose :A com- parative study显示文摘 | Naidu B V K Krishna R K S V Aminabhavi T M | 2005 | Journal of Membrane Science2005，260，12： | 1 |
| 11 | Robust Stability of Discrete-time State-delayed Systems with Saturation Nonlineari- ties : Linear Matrix Inequality Approach 显示文摘 | KRISHNA Rao V KANDANVLI HaranathKar | 2009 | Signal Processing2009，89，： | 1 |
| 12 | Simultaneous auctions with synergies 显示文摘 | Krishna V | 1996 | Games and Economic Behavior1996，17，： | 1 |
| 13 | Treatment of low- strength soluble wastewater using an anaerobic baffled reactor (ABR) 显示文摘 | Gopala Krishna G V T Kumarb P Kumarb P | 2009 | Journal of Environmental Management2009，90，1： | 1 |
| 14 | Low stiffness porous Ti structures for load-bearing implants 显示文摘 | Krishna B V Bose S Bandyopadhyay A | 2007 | Acta Biomaterialia2007，3，6： | 1 |
| 15 | Honey bee behavior inspired load balancing of tasks in cloud computing environments显示文摘 | KRISHNA P V | | Applied Soft Computing0，13，5： | 1 |
| 16 | Studies towardsthe total synthesis of (-)-borrelidin: a strategy for theconstruction of the C11-C15 cyanodiene fragment and theutility of RCM for macrocyclization using model systems 显示文摘 | Krishna C V Maitra S Dev R V | 2006 | Tetrahedr Lett2006，47，34： | 1 |
| 17 | PALSSE: A program to delineate linear secondary structural elements from protein structures 显示文摘 | MAJUMDAR I KRISHNA S S GRISHIN N V | 2005 | BMC Bioinformatics2005，6，1： | 1 |
| 18 | LACAV:An Energy-Effi- cient Channel Assignment Mechanism for Vehicular Ad hoc Net- works显示文摘 | Misra S Venkata Krishna P Saritha V | 2012 | J Supercomput2012，62，5： | 1 |
| 19 | An analysis of the war of attrition and the all-pay auction显示文摘 | Krishna V Morgan J | 2011 | Journal of Economic Theory2011，92，1： | 1 |
| 20 | Permutation Entropy Based Real-Time Chatter Detection Using Audio Signal in Turning Process显示文摘 | Nair U Krishna B M Namboothiri V N N | | 0，，01： | 1 |
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