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| 1 | Assessment of source water contamination by estrogenic disrupting compounds in China显示文摘Detection of estrogenic disrupting compounds(EDCs) in drinking waters around China has led to rising concerns about health risks associated with these compounds.There is,however,a paucity of studies on the occurrence and identification of the main compounds responsible for this pollution in the source waters.To fill this void,we screened estrogenic activities of 23 source water samples from six main river systems in China,using a recombinant two-hybrid yeast assay.All sample extracts induced significant estrogenic activity,with E2 equivalents(EEQ) of raw water ranging from 0.08 to 2.40 ng/L.Additionally,16 samples were selected for chemical analysis by gas chromatography-mass spectrometry.The EDCs of most concern,including estrone(E1),17β-estradiol(E2),17α-ethinylestradiol(EE2),estriol(E3),diethylstilbestrol(DES),estradiol valerate(EV),4-t-octylphenol(4-t-OP),4-nonylphenols(4-NP) and bisphenol A(BPA),were determined at concentrations of up to 2.98,1.07,2.67,4.37,2.52,1.96,89.52,280.19 and 710.65 ng/L,respectively.Causality analysis,involving comparison of EEQ values from yeast assay and chemical analysis identified E2,EE2 and 4-NP as the main responsible compounds,accounting for the whole estrogenic activities(39.74% to 96.68%).The proposed approach using both chemical analysis and yeast assay could be used for the identification and evaluation of EDCs in source waters of China. | Weiwei Jiang YeYan Mei Ma Donghong Wang Qian Luo Zijian Wang Senthil Kumaran Satyanarayanan | 2012 | Journal of Environmental Sciences2012,24,2: | 29 |
| 2 | Retinoid X receptor activities of source waters in China and their removal efficiencies during drinking water treatment processes显示文摘There is increasing evidence of estrogenic activities of source waters and drinking waters in China based on estrogen receptors(ERs) testing.However,relating such activities to retinoid X receptors(RXRs) in both drinking and source waters are lacking.To rectify this situation,we assessed 23 source water samples from six major river systems in China.We also collected samples at various stages of water processing from three drinking water treatment plants(DWTPs) using a two-hybrid RXR yeast assay with and without metabolism.No RXR agonistic activity was observed,but significant antagonistic activity was detected in all sample extracts.The RXR antagonistic activities of source water sample extracts ranged from 15.2% to 57.8% without metabolism and 11.5% to 68.3% with metabolism,respectively.In the drinking water treatment processes,RXR antagonistic activities without metabolism and with metabolism of up to 31.4% and 37.5% were removed,respectively.Nevertheless,the remaining RXR antagonists in treated drinking water from these source waters could still be harmful to human health.To the best of our knowledge,the occurrence of in vitro RXR disruption activities in source and drinking water has not been previously reported in China.Therefore,an attempt was made to conduct detailed studies investigating RXR disrupting activities and their possible risks in source and drinking water. | JIANG WeiWei YAN Ye LI Na MA Mei WANG DongHong RAO KaiFeng WANG ZiJian SATYANARAYANAN Senthi Kumaran | 2012 | Chinese Science Bulletin2012,57,6: | 5 |
| 3 | Geochemical systematics of komatiite-tholeiite and adakite-arc basalt associations:the role of a mantle plume and convergent margin in formation of the Sandur Superterrane,Dharwar Craton,India显示文摘 | Manikyamba C Kerrich R Khanna T.C Krishna A.K Satyanarayanan M | | 0,,: | 1 |
| 4 | Direct electron transfer with yeast cells and construction of a mediatorless microbial fuel cell显示文摘 | D. Prasad S. Arun M. Murugesan S. Padmanaban R.S. Satyanarayanan Sheela Berchmans V. Yegnaraman | 2006 | Biosensors and Bioelectronics2006,,11: | 1 |
| 5 | Coda:a highly available file system,for a distributed WorkStation environment显示文摘 | Satyanarayanan M Kistler J J Kumar P | 1989 | IEEE Transaction on Computers1989,39,4: | 1 |
| 6 | Pervasive personal computing in an internet suspend/resume system显示文摘 | Satyanarayanan M Gilbert B Toups M | | 0,,02: | 1 |
| 7 | Pervasive computing: vision and challenges显示文摘 | Satyanarayanan M | 2001 | IEEE Personal Communications2001,8,4: | 1 |
| 8 | Swiss army knife or wallet显示文摘 | Satyanarayanan M | 2005 | IEEE Pervasive Computing2005,4,2: | 1 |
| 9 | Managing battery lifetime with energy-aware adaptation 显示文摘 | Flinn J Satyanarayanan M | 2004 | ACM Trans on Computer Systems2004,22,2: | 1 |
| 10 | The evolution of coda 显示文摘 | Satyanarayanan M | 2002 | ACM Transactions on Computer Systems2002,50,2: | 1 |
| 11 | Coda:A highly available file system for a distributed workstation environment显示文摘 | M Satyanarayanan J J Kistler P Kumar | 1990 | IEEE Transactions on Computers1990,39,4: | 1 |
| 12 | Pervasive Computing:Vision and Challenges 显示文摘 | Satyanarayanan M | 2001 | IEEE Personal Communications2001,8,3: | 1 |
| 13 | Pervasive computing: vision and challenges 显示文摘 | Satyanarayanan M | 2001 | Personal Communications IEEE2001,8,4: | 1 |
| 14 | Pervasive computing: vision and challenges显示文摘 | SATYANARAYANAN M | 2002 | IEEE Personal Communications2002,8,4: | 1 |
| 15 | Seamless mobile computing on fixed infrastructure显示文摘 | KOZUCH M SATYANARAYANAN M BRESSOUD T | 2004 | IEEE Computer2004,32,7: | 1 |
| 16 | Pervasive computing:Vision and challenges显示文摘 | | 2001 | IEEE Personal Communications2001,8,4: | 1 |
| 17 | Pervasive computing: Vision and challenges显示文摘 | Satyanarayanan M | 2001 | IEEE Personal Communications August2001,5,8: | 1 |
| 18 | Disconnected opera- tion in the Coda file system显示文摘 | KIS'FLER J SATYANARAYANAN M | 1992 | ACM Transactions on Computer Systems1992,10,: | 1 |
| 19 | Quan-tifying Interactive User Experience on Thin Clients显示文摘 | TOLIA N ANDERSEN D SATYANARAYANAN M | 2006 | Com-puter2006,39,3: | 1 |
| 20 | Managing battery lifetime with energy-aware adaptation 显示文摘 | Flinn J Satyanarayanan M | 2004 | ACM Trans on Computer Systems (TOCS)2004,22,2: | 1 |