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8篇 您的检索式:作者名="Koichi Ichimura"
    题名 作者 年代 出处 被引量
1Clinicopathological characteristics of human epidermal growth factor receptor 2-positive Barrett's adenocarcinoma显示文摘AIM:To compare the clinicopathological characteristics of human epidermal growth factor receptor 2 (HER2)-positive and HER2-negative Barrett's adenocarcinoma in Japan. METHODS:We performed immunohistochemical analysis of HER2 in 30 samples taken from patients with Barrett's adenocarcinoma and dual color in situ hybridization in cases showing 2+ reactions. We compared the clinicopathological characteristics of HER2-positive and HER2-negative patients.RESULTS:HER2 positivity was identified in 8 (27%) carcinoma samples. We found that HER2 expression was associated with p53 overexpression (100% vs 52.6% in pT1 tumor; 100% vs 54.5% in all stage tumor, P < 0.05) and protruding lesions at the early disease stage. There was no association between the mucin phenotype of the carcinomas and prognosis. HER2 expression and low clinical stage were unexpectedly different between Barrett's adenocarcinoma patients and gastric cancer patients, but the macroscopic features may be associated with earlier diagnosis in these patients. CONCLUSION:Our results suggest that HER2-positive Barrett's adenocarcinomas are associated with p53 overexpression and lesion protrusion at the early disease stage.Takehiro Tanaka Atsushi Fujimura Koichi Ichimura Hiroyuki Yanai Yasuharu Sato Katsuyohi Takata Hiroyuki Okada Seiji Kawano Shunsuke Tanabe Tadashi Yoshino 2012World Journal of Gastroenterology2012,18,43:2
2Allogeneic hematopoietic stem cell transplantation for advanced extranodal natural killer/T-cell lymphoma, nasal type显示文摘Daisuke Ennishi Yoshinobu Maeda Nobuharu Fujii Eisei Kondo Katsuji Shinagawa Kazuma Ikeda Koichi Ichimura Tadashi Yoshino Mitsune Tanimoto 2011Leukemia & Lymphoma2011,,7:1
3Increased Incidence of Follicular Lymphoma in the Duodenum显示文摘Tadashi Yoshino Kenji Miyake Koichi Ichimura Tomohiko Mannami Nobuya Ohara Shuji Hamazaki Tadaatsu Akagi 2000The American Journal of Surgical Pathology2000,,5:1
4Present state of corrosion inhibitors in Japan 显示文摘Soeda Koichi Ichimura 2003Cement and Concrete Composites2003,25,1:1
5Present state of corrosion in hibitors inJapan 显示文摘Soeda Koichi Ichimura Takao 2003Cement and Concrete Composites2003,95,1:1
6Effect of Meropenem on Disposition Kinetics of Valproate and Its Metabolites in Rabbits显示文摘Koichi Yokogawa Satsuki Iwashita Akira Kubota Youko Sasaki Junko Ishizaki Masami Kawahara Ryo Matsushita Kazuko Kimura Fujio Ichimura Ken-ichi Miyamoto 2001Pharmaceutical Research2001,,9:1
7Present state of corrosion inhibitors in Japan显示文摘Koichi Soeda Takao Ichimura 2003Cememnt & concrete composites2003,25,:1
8Molecular pathogenesis of IDH mutations in gliomas显示文摘Koichi Ichimura 2012Brain Tumor Pathology2012,,3:1
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