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| 1 | Endoscopic ultrasound staging for early esophageal cancer: Are we denying patients neoadjuvant chemo-radiation?显示文摘AIM To evaluate the accuracy of endoscopic ultrasound(EUS) in early esophageal cancer(EC) performed in a highvolume tertiary cancer center. METHODS A retrospective review of patients undergoing esophagectomy was performed and patients with c T1 N0 and c T2 N0 esophageal cancer by EUS were evaluated. Patient demographics, tumor characteristics, and treatment were reviewed. EUS staging was compared to surgical pathology to determine accuracy of EUS. Descriptive statistics was used to describe the cohort. Student's t test and Fisher's exact test or χ~2 test was used to compare variables. Logistic regression analysis was used to determine if clinical variables such as tumor location and tumor histology were associated with EUS accuracy.RESULTS Between 2000 and 2015, 139 patients with clinical stage Ⅰ or Ⅱ?A esophageal cancer undergoing esophagectomy were identified. There were 25(18%) female and 114(82%) male patients. The tumor location included the middle third of the esophagus in 11(8%) and lower third and gastroesophageal junction in 128(92%) patients. Ninety-three percent of patients had adenocarcinoma. Preoperative EUS matched the final surgical pathology in 73/139 patients for a concordance rate of 53%. Twenty-nine patients(21%) were under-staged by EUS; of those, 19(14%) had unrecognized nodal disease. Positron emission tomography(PET) was used in addition to EUS for clinical staging in 62/139 patients. Occult nodal disease was only found in 4 of 62 patients(6%) in whom both EUS and PET were negative for nodal involvement. CONCLUSION EUS is less accurate in early EC and endoscopic mucosal resection might be useful in certain settings. The addition of PET to EUS improves staging accuracy. | Carrie Luu Marisa Amaral Jason Klapman Cynthia Harris Khaldoun Almhanna Sarah Hoffe Jessica Frakes Jose M Pimiento Jacques P Fontaine | 2017 | World Journal of Gastroenterology2017，23，46： | 8 |
| 2 | Plastic biliary stent patency in patients with locally advanced pancreatic adenocarcinoma receiving downstaging chemotherapy显示文摘 | Phillip S. Ge Christopher M. Hamerski Rabindra R. Watson Srinadh Komanduri Birtukan B. Cinnor Kiran Bidari Jason B. Klapman Cui L. Lin Janak N. Shah Sachin Wani Timothy R. Donahue V. Raman Muthusamy | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 3 | A lupus-like syndrome associated with infliximab therapy显示文摘 | Klapman JB Ene-Stroescu D Beeker MA | 2003 | Inflamm Bowel Dis2003，9，3： | 1 |
| 4 | Clinical impact of on-site cytopathology interpretation on endoscopic ultrasound-guided fine needle aspiration显示文摘 | Jason B Klapman Roberto Logrono Charles E Dye Irving Waxman | 2003 | The American Journal of Gastroenterology2003，，6： | 1 |
| 5 | Clinical impact of on-site cytopathology interpretation on endoscopic ultrasound-guided fine needle aspiration显示文摘 | Klapman JB Logrono R Dye CE | 2003 | Am J Gastroenterol2003，98，6： | 1 |
| 6 | Early detection of pancreatic; cancer显示文摘 | Jason Klapman | 2008 | Cancer Control2008，15，4： | 1 |
| 7 | Early detection of pancreatic cancer: why, who, and how to screen显示文摘 | Klapman J Malafa MP | 2008 | Cancer Control2008，15，4： | 1 |
| 8 | Endoscopic ultrasound-guided fine- needle injection显示文摘 | Klapman J B Chang K J | 2005 | Gastrointest Endosc Clin N Am2005，15，1： | 1 |
| 9 | Thickening and nodules in port-wine stains显示文摘 | Klapman MH Yao JF | 2001 | J Am Acad Dermatol2001，44，2： | 1 |
| 10 | Early detection of pancreatic cancer: why,who, and how to screen显示文摘 | Klapman J Malafa MP | 2008 | Cancer Control2008，15，4： | 1 |
| 11 | Transjugular shunt ( TIPS ) for Budd-Chiari syndrome or portal vein thrombosis:review of indications and problems 显示文摘 | Ganger DR Klapman JB intrahepatic portosystemic McDonald V | 1999 | Am J Gastroenterol1999，94，3： | 1 |
| 12 | Thickening and nodules in port-wine stains显示文摘 | Klapman MH Yao JF | 2001 | J Am Acad Dermatol2001，44，2： | 1 |
| 13 | Thickening and nodules in port-wine stains 显示文摘 | Klapman MH Yao JF | 2001 | J Am Acad Dermatol2001，44，2： | 1 |
| 14 | Thickening and nodules in port-wine stains显示文摘 | Klapman MH Yao JF | 2001 | J Am Acad Dermatol2001，44，2： | 1 |
| 15 | Transiugular intrahepatic portosystemic shunt (TIPS) for Budd-Chiari syndrome or portal vein thrombosis: review of indications and problems显示文摘 | Ganger DR Klapman JB McDonald V | 1999 | Am J Gastroenterol1999，94，： | 1 |
| 16 | Stability of endoscopic ultrasound-guided fiducial marker placement for esophageal cancer target delineation and image-guided radiation therapy显示文摘 | Daniel C. Fernandez Sarah E. Hoffe James S. Barthel Shivakumar Vignesh Jason B. Klapman Cynthia Harris Khaldoun Almhanna Matthew C. Biagioli Kenneth L. Meredith Vladimir Feygelman Nikhil G. Rao Ravi Shridhar | 2012 | Practical Radiation Oncology2012，，： | 1 |
| 17 | Minimally invasive mediastinal staging of non-small-cell lung cancer:emphasis on ultrasonography-guided fine-needle aspiraion显示文摘 | Harris CL Toloza EM Klapman JB | 2014 | Cancer Control2014，21，： | 1 |
| 18 | Endoseopic ultrasound-gulded fine-needle injeetion显示文摘 | Klapman J B ChangK J | 2005 | Gastrointest Endosc Clin N Am2005，15，1： | 1 |
| 19 | Management of persistent gas-troesophageal anastomotic strictures with removable self-expandable pol-yester silicon-covered(Polyflex)stents:an alternative to serial dilation 显示文摘 | Barthel J S Kelley S T Klapman J B | 2008 | Gastrointest Endose2008，67，3： | 1 |
| 20 | Early detection of pancreatic cancer: why, who, and how to screen显示文摘 | Klapman J Malafa MP | 2008 | Cancer Control2008，15，4： | 1 |
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