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| 1 | A novel antimicrobial flavonoidic glycoside from the leaves of Alstonia macrophylla Wall ex A.DC(Apocynaceae)显示文摘A new flavonoidic glycoside,tricin-4’-O-β-L-arabinoside(1) was isolated from the leaves of Alstonia macrophylla along with two known flavonoids,vitexin and myricetin-3′-rhamnoside-3-O-galactoside.Their structures were established by chemical and spectral evidences.The known compounds were reported for the first time from this plant.Moreover compound 1 was tested for antifungal and antibacterial activities. | Mehtab Parveen Zakia Khanam Akhtar Ali Syed Mohmud Ahmad | 2010 | Chinese Chemical Letters2010，21，5： | 3 |
| 2 | In vivo anticancer activity of vanillin semicarbazone显示文摘Objective:To evaluate the anticancer activity of vanillin semicarbazone(VSC) against Ehrlich ascites carcinoma(EAC) cells in Swiss albino mice.Methods:The compound VSC at three doses(5, 7.5 and 10 mg/kg i.p.) was administered into the intraperitoneal cavity of the EAC inoculated mice to observe its efficiency by studying the cell growth inhibition, reduction of tumour weight,enhancement of survival time as well as the changes in depleted hematological parameters. Allsuch parameters were also studied with a known standard drug bleomycin at the dose of 0.3 mg/kg(i.p.).Results:Among the doses studied, 10 mg/kg(i.p.) was found to be quite comparable in potency to that of bleomycin at the dose of 0.3 mg/kg(i.p.). The host toxic effects of VSC was found to be negligible.Conclusions:It can be concluded that VSC can therefore be considered as potent anticancer agent. | Shaikh M Mohsin Ali M Abul Kalam Azad Mele Jesmin Shamim Ahsan M Mijanur Rahman Jahan Ara Khanam M Nazrul Islam Sha M Shahan Shahriar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 2 |
| 3 | Histamine H recep- tor antagonists in relation to epilepsy and neurodegenera- tion: a systemic consideration of recent progress and per- spectives 显示文摘 | Bhowmik M Khanam R Vohora D | 2012 | Br J Pharmaeol2012，167，7： | 1 |
| 4 | Study on Associa- tion of Maternal Serum Triglyceride with Pre-eclampsia 显示文摘 | Manna FN Khanam NN Chowdhttry KA | 2015 | My- mensingh Med J2015，24，3： | 1 |
| 5 | Effect of planting tlmes,maturlty stages and iba in stem cuttings of bougainvillea (Bougainvilleas spectabilis ) 显示文摘 | Habib M A Alam K H Khanam M H A etal | 2007 | International Journal of Sustainable Agricultural Technology2007，3，4： | 1 |
| 6 | Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains Ⅲ of these two serotypes显示文摘 | Khanam S Etemad B Khanna N | 2006 | AM J Trop Med Hyp2006，74，2： | 1 |
| 7 | Diabetes and impaired fasting glycemia in a rural population of Bangladesh显示文摘 | Sayeed M A Mahtab H Akter Khanam P | 2003 | Diabetes Care2003，26，4： | 1 |
| 8 | Role of cysteinyl leukotrienes in airway inflammation and responsiveness following RSV infection in BALB/c mice显示文摘 | Fullmer JJ KhanAM ElidemirO | | 0，，07： | 1 |
| 9 | Sphincter saving sur- gery is the standard procedure for treatment of low reetal cancer 显示文摘 | Rahman MS Khair MA Khanam F | 2013 | Mymensingh Med J2013，22，2： | 1 |
| 10 | Effect of edaphic factors on root colonization and spore popula- tion of arbuscular mycorrhizal fungi 显示文摘 | Khanam D Mridha M A U Solaiman A R M | 2006 | Bulletin of the Institute of Tropical Agriculture Kyushu University2006，29，1： | 1 |
| 11 | Antineoplas- tic activity of N-(2-hydroxybenzylidene) 2'-hydroxyphe- nylimine aqua nickel( II ) complex on ehrlich ascites carcinoma (EAC) in Swiss albino mice 显示文摘 | Hossain I A Khanam J A Jesmin M | 2016 | Exp Toxieol Pathol2016，68，1： | 1 |
| 12 | Preva- lence and determinants of pre-hypertension and hyperten- sion among the adults in rural Bangladesh: findings from a community-based study显示文摘 | Khanam M A Lindeboom W Razzaque A | 2015 | BMC Public Health2015，28，15： | 1 |
| 13 | Microparticle Charac- terization Using Digital Holography显示文摘 | Darakis E Khanam T Rajendran A | 2010 | Chemical Engineering Sci- ence2010，，65： | 1 |
| 14 | Electrospun linear polyethyleneimine scaffolds for cell growth显示文摘 | Nadia Khanam Carole Mikoryak Rockford K. Draper Kenneth J. Balkus | 2007 | Acta Biomaterialia2007，，6： | 1 |
| 15 | Influence of ionic and nonionic hydrotropes on micellar behavior of a cationic Gemini surfactant butanediyl-1,4-bis (dimethylcetylammonium bromide)显示文摘 | Khan IA Khanam A J Sheikh MS | | 0，，02： | 1 |
| 16 | Anti-inflammatory effects of plumbagin are mediated by inhibi-tion of NF-kappaB activation in lymphocytes显示文摘 | Checker R Sharma D Sandur SK Khanam S Poduval TB | | 0，，： | 1 |
| 17 | Pharmacokinetic evaluation,molecular docking and in vitro biological evaluation of 1,3,4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors显示文摘1, 3, 4-Oxadiazole derivatives(4 a–5 f) were previously synthesized to investigate their anticancer properties.However, studies relating to their antioxidant potential and signal transducer and activator of transcription(STAT) inhibition have not been performed. We investigated previously synthesized 1, 3, 4-oxadiazole derivatives(4 a–5 f) for various radical scavenging properties using several in vitro antioxidant assays and also for direct inhibition of STAT3 through molecular docking. The data obtained from various antioxidant assays such as 2, 2,-diphenyl-1-picrylhydrazyl radical(DPPH), nitric oxide, hydrogen peroxide, and superoxide anion radical revealed that among all the derivatives, compound 5 e displayed high antioxidant activities than the standard antioxidant L-ascorbic acid. Additionally, the total reduction assay and antioxidant capacity assay further confirmed the antioxidant potential of compound 5 e. Furthermore, the molecular docking studies performed for all derivatives along with the standard inhibitor STX-0119 showed that binding energy released in direct binding with the SH2 domain of STAT3 was the highest for compound 5 e(-9.91 kcal/mol).Through virtual screening, compound 5 e was found to exhibit optimum competency in inhibiting STAT3 activity. Compound 5 e decreased the activation of STAT3 as observed with Western blot. In brief, compound5 e was identified as a potent antioxidant agent and STAT3 inhibitor and effective agent for cancer treatment. | Rashmin khanam Iram I.Hejazi Syed Shahabuddin Abdul R.Bhat Fareeda Athar | 2019 | Journal of Pharmaceutical Analysis2019，9，2： | 1 |
| 18 | Branch?retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications显示文摘 | Jaulim A Ahmed B Khanam T | 2013 | An update of the literature Retina2013，33，5： | 1 |
| 19 | Protective effect of capsaicin against methyl methanesulphonate induced toxicity in the third instar larvae of transgenic Drosophila melanogaster(hsp70-lacZ)Bg9显示文摘Capsaicin(trans-8-methyl-N-vanillyl-6-nonenamide) is the main component in hot peppers, including red chili peppers, alapenos, and habanero, belonging to the genus Capsicum. Capsaicin is a potent antioxidant that interferes with free radical activities. In the present study, the possible protective effect of capsaicin was studied against methyl methanesulphonate(MMS) induced toxicity in third instar larvae of transgenic Drosophila melanogaster(hsp70-lacZ)Bg^9. The third instar was allowed to feed on the diet having different doses of capsaicin and MMS separately and in combination. The results suggested that the exposure of third instar larvae to the diet having MMS alone showed significant hsp70 expression as well as tissue DNA and oxidative damage, whereas the larvae feed on the diet having MMS and capsaicin showed a decrease in the toxic effects for 48-h of exposure. In conclusion, capsaicin showed a dose-dependent decrease in the toxic effects induced by MMS in the third instar larvae of transgenic Drosophila melanogaster. | Saba Khanam Ambreen Fatima Rahul Smita Jyoti Fahad Ali Falaq Naz Barkha Shakya Yasir Hasan Siddique | 2017 | Chinese Journal of Natural Medicines2017，15，4： | 1 |
| 20 | Arterial oxygention during one-lung anethesia study in man 显示文摘 | Khanam T Branfhwarfe MD | 1978 | Anesthesia1978，28，： | 1 |
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