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| 1 | Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells显示文摘砷三氧化物(ATO ) 能在肿瘤房间作为反肿瘤药导致区别和 apoptosis。间充质的干细胞(MSC ) 在骨头髓的造血作用起重要作用。许多报告证明了 MSC adipogenic 和 osteogenic 区别的混乱发生在一些疾病。然而,关于 MSC 上的 ATO 的效果的报告是有限的。在这研究,我们发现 1 M ATO 主要通过 p21 支持了 MSC 老朽,尽管它没在这剂量在 apoptosis 上有效果。而且, ATO 支持了 adipogenic 区别,但是在 MSC 禁止了 osteogenic 区别。我们的学习也显示出那 CCAAT/enhancer-binding 蛋白质 alpha C/EBP 和 peroxisome 激活 proliferator 的受体 gamma PPAR 可能涉及 ATO 导致的 adipogenic 和 osteogenic 区别的规定。我们的结果显示 ATO 可以由影响骨头髓微型环境施加反肿瘤效果。而且,它可以调整 MSC 的 adipogenic 和 osteogenic 区别。 | Huanchen Cheng Lin Qiu Hao Zhang Mei Cheng Wei Li Xuefei Zhao Keyu Liu Lei Lei Jun Ma | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 8 |
| 2 | Applications of Light Stable Isotopes(C, O, H) in the Study of Sandstone Diagenesis: A Review显示文摘This article reviews the applications of light stable isotope, including carbon, oxygen and hydrogen, in thestudies on origin and formation temperature of authigenic carbonate, quartz and clay minerals. Theoretical knowledge andanalytical methods for major light stable isotopes are introduced in detail. Negative and positive δ^(13)C values indicatesignificant differences on the origin of carbonate cements. The δ^(18)O value is an effective palaeotemperature scale forauthigenic minerals formation. Various fractionation equations between δ^(18)O and temperature are proposed for carbonatecements, quartz cements and clay minerals, whose merit and demerit, applicable conditions are clarified clearly. Clumpedisotope analysis can reconstruct the temperature of carbonate precipitation with no requirement on the δ^(18)O of initial waters,which makes temperature calculation of carbonate cements formation more convenient and accurate. Hydrogen and oxygenisotopes mainly reflect the origin of diagenetic fluid for clay mineral formation, providing reliable evidence for diageneticenvironment analysis. This work aims at helping researchers for better understanding the applications of light stable isotopein sandstone diagenesis. | XI Kelai CAO Yingchang LIN Miruo LIU Keyu WU Songtao YUAN Guanghui YANG Tian | 2019 | Acta Geologica Sinica(English Edition)2019，93，1： | 4 |
| 3 | Effect of laser remelting on corrosion behavior of plasma-sprayed Ni-coated WC coatings显示文摘 | Xie Guozhi Zhang Jingxian Lu Yijun Wang Keyu Mo Xiangyin Lin Pinghua | 2007 | Materials Science & Engineering A2007，，： | 1 |
| 4 | Corrosion characteristics of plasma-sprayed Ni-coated WC coatings comparison with different post-treatment显示文摘 | XIE GUOZHI LIN XIAOYAN WANG KEYU | 2007 | Corrosion Science2007，49，： | 1 |
| 5 | Corrosion characteristics of plasma-sprayed Ni-coated WC coatings comparison with different post-treatment 显示文摘 | Xie Guozhi Lin Xiaoyan Wang Keyu | 2007 | Corrosion Science2007，49，2： | 1 |
| 6 | Specific Index System of Ecological Balanced Fertilization for Maize显示文摘This paper studied the index system of ecological balanced fertilization for maize by data mining method based on data of'3414 fertilizer field trials'of maize by published papers from national soil testing and recommendation since 2005.The results and conclusions were as follows.①Soil nutrient content could not be used as indicator of fertilizer application of maize.②The conceptual model of N conversion rate of maize for plot was Y N≈a+b×optimum production-c×optimum fertilizer amount of N-d×optimum phosphorus application amount-e×optimum potassium application amount-f×temperature in growth season-g×rainfall in growth season.The conceptual model of P conversion rate of maize for plot was Y P≈a+b×optimum phosphorus application amount-c×optimum nitrogen application amount-d×optimum potassium application amount.The conceptual model of K conversion rate of maize for plot was Y K≈a+b×optimum yield-c×optimum nitrogen application amount-d×optimum phosphorus application amount-e×optimum potassium application amount-f×temperature in growth season-g×rainfall in growth season.③The conceptual model of the optimum fertilizer amount of N of maize for plot was Y N≈a+b×optimum phosphorus application amount+c×optimum potassium application amount+d×temperature in growing season+e×rainfall in growing season,and the conceptual model of the optimum fertilizer amount of P was Y P≈a+b×optimum nitrogen application amount,and the conceptual model of the optimum fertilizer amount of K was Y K≈a+b×optimum nitrogen application amount+c×temperature in growth season+d×rainfall in growth season-e×optimum yield.④The conceptual model of relative abundance-deficiency value of soil N of maize for plot was that Y N≈a,and the conceptual model of relative abundance-deficiency value of soil P was Y P≈a,and the conceptual model of relative abundance-deficiency value of soil K was Y K≈a+b×optimum nitrogen application amount+c×optimum phosphorus application amount. | Keyu LIN Hongyan ZHENG Zhiping HUANG Jian DING Changhong MI Shutian LIU Xianda HOU Shuojin WANG Ling LU Yanlin HOU | 2020 | Meteorological and Environmental Research2020，11，5： | 0 |
| 7 | Rapid and sensitive detection of urinary KIM-1 using fully printed photonic crystal microarrays显示文摘Urinary kidney injury molecule 1(uKIM-1)serves as a reliable marker for the early diagnosis of acute kidney injury(AKI).The rapid and facile detection of changes in uKIM-1 is essential for early AKI diagnosis,ultimately improving the prognosis of patients.In this study,we developed a fully printed photonic crystal-integrated microarray with photonic crystal-enhanced fluorescence properties,which can detect uKIM-1 levels at the point-of-care.We confirmed its efficacy in the early diagnosis of AKI using clinical urine specimens.Direct quantitative detection of uKIM-1 was achieved within 10 min.The lowest limit of detection is 8.75 pg·mL^(-1) with an accuracy of 94.2%.The diagnostic efficacy was validated using 86 clinical urine samples,highlighting the high sensitivity and stability of the photonic crystal microarray.Consequently,a facile and reliable immunoassay was designed and prepared for the rapid quantitative detection of uKIM-1,which is crucial for the early identification and convenient detection of AKI in hospital or community settings.Rapid,convenient,cost-effective,and long-term monitoring of changes in uKIM-1 levels can assist clinicians in making timely adjustments to treatment regimens,preventing the transition from AKI to chronic kidney disease(CKD),improving the quality of life of patients with AKI,and reducing healthcare costs.It highlights the advantages of utilizing urine samples as a noninvasive and easily accessible medium for early detection and monitoring of kidney-related conditions. | Yang Liu Xuwei He Zewei Lian Qian Guo Jimei Chi Xiaoxue Lin Liyue Zhang Zheng Liu Yingyuan Liu Meng Su Keyu Wang Qiangguo Ao Qingli Cheng | 2024 | Nano Research2024，17，5： | 0 |
| 8 | Sharp recanalization using Chiba biopsy needle for the treatment of biliary occlusion after radiofrequency ablation显示文摘Introduction Biliary stricture is a less common complication after hepatic radiofrequency ablation(RFA)[1,2].Patients with biliary stricture often present with recurrent jaundice,fever or chills,and require endoscopic or percutaneous biliary drainage,and in some cases recanalization of the biliary tract[3].Establishing guide-wire passage through the stricture is essential for biliary recanalization.However,in some cases of complete biliary obstruction,a more aggressive technique is needed when ordinarymethods fail to establish.Herein,we report a novel technique of extraluminal recanalization for biliary strictures using a Chiba biopsy needle,which is similar to sharp endovascular recanalization. | Bin Chen Haitao Dai Keyu Tang Run Lin Yonghui Huang | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 9 | Numerical modelling for leak oil flow in tunnel of the cave storage显示文摘Oil storage in cavern tank is one of the important ways of oil storage.More than 80%of the oil tanks in the cave storage have been used for around 30 years in China and leakage accidents are likely to occur.When it occurs,the motor closing facilities preventing leakage spreading should be set up.The leaking oil flow characteristic in tunnel must be known for setting up the motor closing facilities.Based on the open-channel unsteady flow theory,a numerical model of tank leakage coupling the oil flow in tunnel was developed,and the characteristic line method was used to solve the model under the given initial condition and boundary condition.The variation of the depth and flow rate with time of oil flowing in the tunnel can be obtained.In order to verify the accuracy of model,the measurement data of high accuracy experimental system for unsteady open-channel flow were conducted to compare with the calculation.It fully confirms the high precision of the numerical model and reflects the variation characteristics of each hydraulic parameter in the numerical model of unsteady open channel flow truly.And then,the leaking oil flow characteristic in tunnel was obtained.It is that the farther from the leaking tank,the lower depth and flow rate of the oil in the tunnel revealed.Furthermore,the effect of the size of oil tank crack on the depth and flow rate was investigated.The greater size of crack makes the oil flow rate higher and the oil deeper in the tunnel and flow faster. | Jimiao Duan Huishu Liu Shuo Xu Jiang Li Tingao Shen Keyu Lin Hao Yan | 2021 | Petroleum2021，7，3： | 0 |
| 10 | Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome显示文摘The treatment of non-small cell lung cancer(NSCLC)remains a challenge due to tumor evolution during anti-angiogenesis therapies,in which the mechanism of vascular mimicry(VM)is believed to result in ineffective treatment[1].To conquer this challenge,substantial effort has recently been devoted to seeking out natural compounds on account of their multitarget actions.As a traditional herbal medicine,platycodin D(PD)is the major bioactive monomer derived from Platycodon grandiflorum(P.grandiflorum)and is used as an expectorant for pulmonary disease in Asia[2]. | Shuyu Zheng Yanlin Xin Jiamin Lin Zejuan Xie Keyu Cheng Shanshan Wang Wenli Lu Hao Yang Tianming Lu Jun Li Ruogu Qi Yuanyuan Guo | 2024 | Journal of Pharmaceutical Analysis2024，14，1： | 0 |
| 11 | Self-ball milling strategy to construct high-entropy oxide coated LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) with enhanced electrochemical performance显示文摘High-entropy oxides(HEOs)are a new class of emerging materials with fascinating properties(such as structural stability,tensile strength,and corrosion resistance).High-entropy oxide coated Ni-rich cathode materials have great potential to improve the electrochemical performance.Here,we present a facile self-ball milling method to obtain(La_(0.2)Nd_(0.2)Sm_(0.2)Eu_(0.2)Gd_(0.2))_(2)Zr_(2)O_(7)(HEO)coated LiNi_(0.8)Co_(_(0.1))Mn_(_(0.1))O_(2)(NCM811).The HEO coating endows NCM811 with a stable surface,reduces the contact with the external environment(air and electrolyte),and inhibits side reactions between cathode and electrolyte.These favorable effects,especially when the coating amount is 5 wt%,result in a significant reduction of the battery polarization and an increase in the capacity retention from 57.3%(NCM811)to 74.2%(5HEO-NCM811)after 300 cycles at 1 C(1 C=200 mA·h·g^(−1)).Moreover,the morphology and spectroscopy analysis after the cycles confirmed the inhibitory effect of the HEO coating on electrolyte decomposition,which is important for the cycle life.Surprisingly,HEO coating reduces the viscosity of slurry by 37%–38%and significantly improves the flowability of the slurry with high solid content.This strategy confirms the feasibility of HEO-modified Ni-rich cathode materials and provides a new idea for the design of high-performance cathode materials for Li-ion batteries. | Kai YUAN Tianzhe TU Chao SHEN Lin ZHOU Jixuan LIU Jing LI Keyu XIE Guojun ZHANG | 2022 | Journal of Advanced Ceramics2022，11，6： | 0 |
| 12 | Growing curly graphene layer boosts hard carbon with superior sodium-ion storage显示文摘Benefiting from the distinctive ordering degree and local microstructure characteristics,hard carbon(HC)is considered as the most promising anode for sodium-ion batteries(SIBs).Unfortunately,the low initial Coulombic efficiency(ICE)and limited reversible capacity severely impede its extensive application.Here,a homogeneous curly graphene(CG)layer with a micropore structure on HC is designed and executed by a simple chemical vapor deposition method(without catalysts).CG not only improves the electronic/ionic conductivity of the hard carbon but also effectively shields its surface defects,enhancing its ICE.In particular,due to the spontaneous curling structural characteristics of CG sheets(CGs),the micropores(≤2 nm)formed provide additional active sites,increasing its capacity.When used as a sodium-ion battery anode,the HC-CG composite anode displayed an outstanding reversible capacity of 358 mAh·g^(-1),superior ICE of 88.6%,remarkable rate performance of 145.8 mAh·g^(-1)at 5 A·g^(-1),and long cycling life after 1000 cycles with 88.6%at 1 A·g^(-1).This work provides a simple defect/microstructure turning strategy for hard carbon anodes and deepens the understanding of Na+storage behavior in the plateau region,especially on the pore-filling mechanism by forming quasi-metallic clusters. | Minghao Song Qiang Song Tao Zhang Xiaomei Huo Zezhou Lin Zhaowen Hu Lei Dong Ting Jin Chao Shen Keyu Xie | 2023 | Nano Research2023，16，7： | 0 |
| 13 | Preparation and characterization of polymer-clay nanocomposite films显示文摘Polymer/clay nanocomposite films were prepared by means of electrodeposition of aqueous suspension including cathodic electrophoretic acrylic resin (CEAR) and Na+-montmorillonite (NMMT). Studies of XRD,SEM and TEM indicated well-dispersed NMMT platelets in the films prepared. The ideal dispersity achieved was thought to be the result of aqueous compatibility between CEAR molecules and NMMT platelets and the result of the water-involved process as well. The modulus and strength of the polymer/clay nanocomposite coatings tested by tensile testing and nano-indentation were effectively improved compared to those of the virgin CEAR film. In addition,the adhesion strength,flexibility and water-resistance represented by Chinese national standard (GB) kept the best grades. | CHEN KeYu WANG ChangAn HUANG Yong LIN Wei | 2009 | Science China Chemistry2009，52，12： | 0 |
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