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| 1 | Spinal cord injury in the setting of traumatic thoracolumbar fracture is not reliably associated with increased risk of associated intra-abdominal injury following blunt trauma:An analysis of a National Trauma Registry database显示文摘Purpose:There is a common opinion that spinal fractures usually reflect the substantial impact of injuries and therefore may be used as a marker of significant associated injuries,specifically for intra-abdominal injury(IAI).The impact of concomitant spinal cord injury(SCI)with the risk of associated IAI has not been well clarified.The aim of this study was to evaluate the incidence and severity of IAIs in patients suffering from spinal fractures with or without SCI.Methods:A retrospective cohort study using the Israeli National Trauma Registry was conducted.Patients with thoracic,lumbar and thoracolumbar fractures resulting from blunt mechanisms of injury from January 1,1997 to December 31,2018 were examined,comparing the incidence,severity and mortality of IAIs in patients with or without SCI.The collected variables included age,gender,mechanism of injury,incidence and severity of the concomitant IAIs and pelvic fractures,abbreviated injury scale,injury severity score,and mortality.Statistical analysis was performed using GraphPad InStat?Version 3.10,with Chi-square test for independence and two sided Fisher’s exact probability test.Results:Review of the Israeli National Trauma Database revealed a total of 16,878 patients with spinal fractures.Combined thoracic and lumbar fractures were observed in 1272 patients(7.5%),isolated thoracic fractures in 4967 patients(29.4%)and isolated lumbar fractures in 10,639 patients(63.0%).The incidence of concomitant SCI was found in 4.95%(63/1272),7.65%(380/4967)and 2.50%(266/10639)of these patients,respectively.The overall mortality was 2.5%,proving higher among isolated thoracic fracture patient than among isolated lumbar fracture counterparts(11.3%vs.4.6%,p<0.001).Isolated thoracic fractures with SCI were significantly more likely to die than non-SCI counterparts(8.2%vs.3.1%,p<0.001).There were no differences in the incidence of IAIs between patients with or without SCI following thoracolumbar fractures overall or in isolated thoracic fractures;although isolated lumbar fractures patients with SCI were more likely to have renal(3.4%vs.1.6%,p=0.02)or bowel injuries(2.3%vs.1.0%,p=0.04)than the non-SCI counterparts.Conclusion:SCI in the setting of thoracolumbar fracture does not appear to be a marker for associated IAI.However,in a subset of isolated lumbar fractures,SCI patient is associated with increased risks for renal and bowel injury. | Veacheslav Zilbermints Yehuda Hershkovitz Kobi Peleg Joseph J.Dubose Adi Givon David Aranovich Mickey Dudkiewicz Israeli Trauma Group Boris Kessel | 2021 | Chinese Journal of Traumatology2021，24，3： | 9 |
| 2 | Analysis of incidence of traumatic brain injury in blunt trauma patients with Glasgow Coma Scale of 12 or less显示文摘 | Alexander Becket Kobi Peleg Oded Olsha Adi Givon Boris Kessel Israeli Trauma Group | 2018 | Chinese Journal of Traumatology2018，21，3： | 7 |
| 3 | Influence of antibiotic-regimens on intensive-care unit-mortality and liver-cirrhosis as risk factor显示文摘AIM: To assess the rate of infection, appropriateness of antimicrobial-therapy and mortality on intensive care unit(ICU). Special focus was drawn on patients with liver cirrhosis.METHODS: The study was approved by the local ethical committee. All patients admitted to the Internal Medicine-ICU between April 1, 2007 and December 31, 2009 were included. Data were extracted retrospectively from all patients using patient charts and electronic documentations on infection, microbiological laboratory reports, diagnosis and therapy. Due to the large hepatology department and liver transplantation center, special interest was on the subgroup of patients with liver cirrhosis. The primary statistical-endpoint was the evaluation of the influence of appropriate versusinappropriate antimicrobial-therapy on in-hospitalmortality.RESULTS: Charts of 1979 patients were available. The overall infection-rate was 53%. Multiresistantbacteria were present in 23% of patients with infection and were associated with increased mortality(p < 0.000001). patients with infection had significantly increased in-hospital-mortality(34% vs 17%, p < 0.000001). Only 9% of patients with infection received inappropriate initial antimicrobial-therapy, no influence on mortality was observed. Independent risk-factors for in-hospital-mortality were the presence of septicshock, prior chemotherapy for malignoma and infection with pseudomonas spp. Infection and mortality-rate among 175 patients with liver-cirrhosis was significantly higher than in patients without liver-cirrhosis. Infection increased mortality 2.24-fold in patients with cirrhosis. patients with liver cirrhosis were at an increased risk to receive inappropriate initial antimicrobial therapy.CONCLUSION: The results of the present study report the successful implementation of early-goal-directed therapy. Liver cirrhosis patients are at increased risk of infection, mortality and to receive inappropriate therapy. Increasing burden are multiresistant-bacteria. | Mireen Friedrich-Rust Beate Wanger Florian Heupel Natalie Filmann Reinhard Brodt Volkhard AJ Kempf Johanna Kessel Thomas A Wichelhaus Eva Herrmann Stefan Zeuzem Joerg Bojunga | 2016 | World Journal of Gastroenterology2016，22，16： | 6 |
| 4 | 高等职业教育与企业之间校企合作的建立显示文摘信息时代的到来使得高等教育体系中学习和工作的紧密联系越发显现出来。合作教育体系以及基于工作的学习,是实现工学结合的有效手段,在这个体系中,学校和企业紧密合作,学生将学习和工作有机结合。为了探究合作高等教育的发展动因及其阻碍因素,围绕合作教育的评价体系和有关政策,进行了大量的调研和分析。为了推进合作教育体系观念的认可,对高等职业院校和多家企业参与者的合作进行了调研和督察。这种独特的高等教育理念的推广,需要建立质量保证体系来明确人才培养标准和学生如何达到这些标准,还需要清晰描述所涉及各方的责任和义务。高等教育部门和企业参与合作课程的设计,对于双方持续校企合作的建立和发展是非常有帮助的,但还需要克服两者之间文化的差异。 | Joseph Kessels Kitty Kwakman 魏丽红 翟秋喜 | 2010 | 辽宁农业职业技术学院学报2010，12，5： | 4 |
| 5 | Effect of dietary fiber and threonine content on intestinal barrier function in pigs challenged with either systemic E.coli lipopolysaccharide or enteric Salmonella Typhimurium显示文摘Background:The independent and interactive effects of dietary fiber(DF)and threonine(Thr)were investigated in growing pigs challenged with either systemic E.coli lipopolysaccharide(LPS)or enteric Salmonella Typhimurium(ST)to characterise their effect on intestinal barrier function.Results:In experiment 1,intestinal barrier function was assessed via oral lactulose and mannitol(L:M)gavage and fecal mucin analysis in pigs challenged with E.coli LPS and fed low fiber(LF)or high fiber(HF)diets with graded dietary Thr.Urinary lactulose recovery and L:M ratio increased(P<0.05)during the LPS inoculation period in LF fed pigs but not in HF fed pigs.Fecal mucin output was increased(P<0.05)in pigs fed HF compared to LF fed pigs.In experiment 2,RT-qPCR,ileal morphology,digesta volatile fatty acid(VFA)content,and fecal mucin output were measured in Salmonella Typhimurium challenged pigs,fed LF or HF diets with standard or supplemented dietary Thr.Salmonella inoculation increased(P<0.05)fecal mucin output compared to the unchallenged period.Supplemental Thr increased fecal mucin output in the HF-fed pigs(Fib×Thr;P<0.05).Feeding HF increased(P<0.05)VFA concentration in cecum and colon.No effect of either Thr or fiber on expression of gene markers was observed except a tendency(P=0.06)for increased MUC2 expression with the HF diet.Feeding HF increased goblet cell numbers(P<0.05).Conclusion:Dietary fiber appears to improve barrier function through increased mucin production capacity(i.e.,goblet cell numbers,MUC2 gene expression)and secretion(i.e.,fecal mucin output).The lack of effect of dietary Thr in Salmonella-challenged pigs provides further evidence that mucin secretion in the gut is conserved and,therefore,Thr may be limiting for growth under conditions of increased mucin production. | Michael O.Wellington Kimberley Hamonic Jack E.C.Krone John K.Htoo Andrew G.Van Kessel Daniel A.Columbus | 2020 | Journal of Animal Science and Biotechnology2020，11，3： | 3 |
| 6 | Virtual Liver Resection and Volumetric Analysis of the Future Liver Remnant using Open Source Image Processing Software显示文摘 | Joost R. Vorst Ronald M. Dam Rogier S. A. Stiphout Maartje A. den Broek Ilona H. Hollander Alfons G. H. Kessels Cornelis H. C. Dejong | 2010 | World Journal of Surgery2010，，10： | 2 |
| 7 | Radiofrequency Lesion Adjacent to the Dorsal Root Ganglion for Cervicobrachial Pain: A Prospective Double Blind Randomized Study显示文摘 | Maarten van Kleef Leon Liem Richel Lousberg Gerard Barendse Fons Kessels Menno E. Sluijter | 1996 | Neurosurgery1996，，6： | 2 |
| 8 | On-target temporal characterization of optical pulses at relativistic intensity显示文摘High-field experiments are very sensitive to the exact value of the peak intensity of an optical pulse due to the nonlinearity of the underlying processes.Therefore,precise knowledge of the pulse intensity,which is mainly limited by the accuracy of the temporal characterization,is a key prerequisite for the correct interpretation of experimental data.While the detection of energy and spatial profile is well established,the unambiguous temporal characterization of intense optical pulses,another important parameter required for intensity evaluation,remains a challenge,especially at relativistic intensities and a few-cycle pulse duration.Here,we report on the progress in the temporal characterization of intense laser pulses and present the relativistic surface second harmonic generation dispersion scan(RSSHG-D-scan)—a new approach allowing direct on-target temporal characterization of high-energy,few-cycle optical pulses at relativistic intensity. | Vyacheslav E.Leshchenko Alexander Kessel Olga Jahn Mathias Kruger Andreas Münzer Sergei ATrushin Laszlo Veisz Zsuzsanna Major Stefan Karsch | 2019 | Light(Science & Applications)2019，8，1： | 2 |
| 9 | Preoperative Imaging of Colorectal Liver Metastases After Neoadjuvant Chemotherapy: A Meta-Analysis显示文摘 | Charlotte Kessel Constantinus Buckens Maurice Bosch Maarten Leeuwen Richard Hillegersberg Helena Verkooijen | 2012 | Annals of Surgical Oncology2012，，9： | 2 |
| 10 | Influence of the crude oil resin/asphaltene ratio on the stability of oil/water emulsions 显示文摘 | Schorling P C Kessel D G Rahimian I | 1999 | Colloids Surfaces A: Physicochemical and Engineering Aspects1999，152，： | 1 |
| 11 | Comparison of treatment plans for peripheral arterial disease made with multi-station contrast medium-enhanced magnetic resonance angiography and duplex ultrasound scanning显示文摘 | Leiner T Tordoir JH Kessels AG | 2003 | J Vase Surg2003，37，6： | 1 |
| 12 | Regio- and stereospecificity in propene polymerization with MgCl2- supported Ziegler-Natta catalysts: Effects of hydrogen and the external donor显示文摘 | Chadwick J C van Kessel G M M Sudmeijer O | 1995 | Macromol Chem Phys1995，196，5： | 1 |
| 13 | Two clinically distinct lacunar infarct entities? A hypothesis显示文摘 | Boiten J Lodder J Kessels F | 1993 | Stroke1993，24，： | 1 |
| 14 | Sites of photodamage in vivo and in vitro by a cationic porphyrin显示文摘 | Woodburn K Henderson BW | 1995 | Photochem Photobiol1995，62，： | 1 |
| 15 | The inhibition of zinc corrosion by bisaminotriazole and other triazole derivatives显示文摘 | Wippermann K Schuhze J W Kessel R | 1990 | Corrosion Science1990，32，2： | 1 |
| 16 | Separation and chemical charac- terization of wetting crude oil compounds 显示文摘 | Akhlaq M Kessel D Domow W | 1996 | Journal of Colloid and Interface Science1996，180，2： | 1 |
| 17 | Vitrectomy results in diabetic macular oedema w ithout evident vitreomacu-lar traction显示文摘 | La Heij EC Hendrikse F Kessels AG Derhaag PJ | 2001 | Graefes Arch Clin Exp Ophthalmol2001，239，4： | 1 |
| 18 | Rapid on-farm analysis of manure nutrients using quick tests显示文摘 | Van Kessel Thompson J S R B Reeves J B III | 1999 | Journal of Production Agriculture1999，12，： | 1 |
| 19 | β- ( 1 →3,1 →4 ) oat glucan enhances resistance to Eimeria vermiformis infection in immunosuppressed mice显示文摘 | Heuiyun C Estrada A Kessel A V | 1997 | International Journal for Parasitology1997，27，3： | 1 |
| 20 | Development andqualification of the parallel line model for the estimation of humaninfluenza haemagglutinin content using the single radial immunod-iffusion assay显示文摘 | Van Kessel G Geels MJ De Weerd S | 2012 | Vaccine2012，30，2： | 1 |
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