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| 1 | Medicinal mushrooms in supportive cancer therapies:an approach to anti-cancer effects and putative mechanisms of action显示文摘Medicinal mushrooms have been valued as natural sources of bioactive compounds since times immemorial and have been recognized as potential immunomodulating and anti-cancer agents.Their consumption has consistently been shown to have beneficial effects on human health.Cancer is a generic term for several types of diseases that can be chronic and are responsible for a large number of deaths worldwide.Although there has been considerable progress in modern cancer therapy research,difficulties in understanding the molecular behavior of various types of cancers and the numerous side effects experienced by patients from treatments means that this whole subject area is still problematic.Thus,biological immunotherapy using natural bioactive compounds as supportive treatments in conventional cancer therapies has become in vogue.Bioactive metabolites isolated from medicinal mushrooms have shown potential successes in cancer treatment as biological immunotherapeutic agents that stimulate the immune system against cancer cells.They also act as an effective source of anti-cancer agents,capable of interfering with cellular signal transduction pathways linked to cancer development and progression.In this review we compile available data on the characteristics of medicinal mushrooms that appear to be particularly effective as biological immunotherapeutic agents.Major consideration is given to biological constituents and the putative mechanisms of action by which bioactive compounds act on the human body.Consideration is also given to the benefits that have been claimed for the use of mushrooms in treating cancer and the future prospects of using medicinal mushrooms as potent supportive candidate bioagents for treatment of cancers is discussed. | Dilani D.De Silva Sylvie Rapior Françoise Fons Ali H.Bahkali Kevin D.Hyde | 2012 | Fungal Diversity2012，，4： | 5 |
| 2 | Presenting mitochondrial antigens: PINK1, Parkin and MDVs steal the show显示文摘 | Rosalind F Robertst Edward A Fon | 2016 | Cell Research2016，26，11： | 3 |
| 3 | 根据地温异常识别油气显示文摘热量从地球深处向上运移,最终到达地表。在不同的深度,温度亦不相同,其变化取决于热量所经过的地下物质(固体和液体)的类型。与非隔热地层相比,假如一特殊的地下物质层具有隔热能力,如油气储层,那么该层下部的地温会较高,而其上部的地温则较低。因此,温度图将会显示出油气层上部(和下部)地层的温度异常。本文将讨论温度异常测绘(TAM)的基本原理,利用该原理可根据不同区域的地表温度变化来识别地下油气。在地表以下,利用温度梯度异常可识别一口井的总井深(TD)下方是否存在额外的油气。 | Lioyd Fons 张继民 张桂勤 刘锋 | 2001 | 石油物探译丛2001，，2： | 3 |
| 4 | Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon显示文摘Background:Tuberculosis(TB)remains a global health challenge and depression is a significant contributor to the global burden of disease.Current evidence suggests that there is an association between depressive symptoms and TB,lower adherence to treatment,and increased morbidity and mortality.However,there is paucity of data regarding these associations in Cameroon.This study aimed to determine the prevalence and correlates of depression in adult patients with pulmonary TB(PTB)in the Southwest Region of Cameroon.Methods:A hospital-based cross-sectional study involving 265 patients with PTB was conducted from 2nd January to 31st March 2015 in the Limbe Regional Hospital and the Kumba District Hospital.Depression was diagnosed using the standard nine-item Patient Health Questionnaire,and classified as none,mild or moderate.Logistic regressions were used to investigate correlates of depression in these patients.Results:Of the 265 patients(mean age 36.9±10 years)studied,136(51.3%)were female.The prevalence of depression was 61.1%(95%CI:55.1–66.8),with a significant proportion(36.6%)having mild depression.Multivariable logistic regression analysis showed that being female(aOR=3.0,95%CI(1.7–5.5),P<0.001),having a family history of mental illness(aOR=2.5,95%CI:1.3–5.4,P>0.05),being on retreatment for TB(aOR=11.2,95%CI:5.2–31.1,P<0.001),having discontinued treatment(aOR=8.2,95%CI:1.1–23.3,P<0.05)and having a HIV/TB co-infection(aOR=2.5,95%CI:1.2–6.5,P<0.001)were factors associated with having a higher chance of being depressed.Conclusion:Our study suggests that there is a high prevalence of depression among PTB patients,with more than one in two patients affected.Multidisciplinary care for TB patients involving mental health practitioners is highly encouraged,especially for high-risk groups. | Jules Kehbila Cyril Jabea Ekabe Leopold Ndemnge Aminde Jean Jacques NNoubiap Peter Nde Fon Gottlieb Lobe Monekosso | 2016 | Infectious Diseases of Poverty2016，5，1： | 3 |
| 5 | Radiofrequency Lesion Adjacent to the Dorsal Root Ganglion for Cervicobrachial Pain: A Prospective Double Blind Randomized Study显示文摘 | Maarten van Kleef Leon Liem Richel Lousberg Gerard Barendse Fons Kessels Menno E. Sluijter | 1996 | Neurosurgery1996，，6： | 2 |
| 6 | Uniaxial locked epitaxy of ZnO on the face of sapphire显示文摘 | FONS P IWATA K YAMADA A | 2000 | Appl Phys Lett2000，77，： | 1 |
| 7 | Developing mobile business processes for the Internet of Things显示文摘 | GINER P CETINA C FONS J | 2010 | IEEE Pervasive Computing2010，9，2： | 1 |
| 8 | Molecular mechanisms of neurotransmitter release显示文摘 | Fon EA Edwards RH | | 0，，： | 1 |
| 9 | Soluble HLA-G and control of angiogenesis显示文摘 | Le Bouteiller P Fons P Herault JP | 2007 | J Reprod Immunol2007，76，12： | 1 |
| 10 | Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging 显示文摘 | Alfons S K de Hooqe Fons A J van de Loo | 2005 | Osteoarth Cartilage2005，13，1： | 1 |
| 11 | The Innovative Electronic Resource Management System:A Development Partnership显示文摘 | Diane Grover Theodore Fons | 2004 | Serials Review2004，30，2： | 1 |
| 12 | Re- al-time embedded systems powered by FPGA dynamic par- tial self-reconfignration: A case study oriented to biometric recognition applications 显示文摘 | Francisco Fons Mariano Fons Enrique Canto | 2013 | Real-Time Image Processing2013，8，3： | 1 |
| 13 | Using Default Rates to Model the Term Structure of Credit Spreads 显示文摘 | Fons Jerome S | 1994 | Financial Analysts Journal1994，9，： | 1 |
| 14 | Long-term outcome after an early invasive versus selective invasive treatment strategy in patients with non-ST-elevation acute coronary syndrome and elevated cardiac troponin T (the ICTUS trial): a follow-up study显示文摘 | Alexander Hirsch Fons Windhausen Jan GP Tijssen Freek WA Verheugt Jan Hein Cornel Robbert J de Winter | 2007 | The Lancet . 2007 (9564)2007，，9564： | 1 |
| 15 | Serious about Series LLCS显示文摘 | Brian R Fons | 2007 | Chicago Bar Association CBA Record2007，，： | 1 |
| 16 | Chem oprevention of gastric dysplasia: randomized trial of ant ioxidant supplements and anti-helieobacter pylori therapy 显示文摘 | Correa P Fon tham ET Bravo JC | 2000 | J Natl Cancer Inst2000，92，23： | 1 |
| 17 | Isolation and characterization of a plasmid from Lactobacillus fermentum conferring erythromycin resistance显示文摘 | Fons M Hege T Ladire M | 1997 | Plasmid1997，37，3： | 1 |
| 18 | Commercial Choice of Law in Context: Looking Beyond R ome显示文摘 | Manuel Penadés Fons | 2015 | Mod. L. Rev2015，，2： | 1 |
| 19 | The Effects of Government Subsidy Measures on Corporate R&D Expenditure: a Case Study of the Leading Product Development Programme 显示文摘 | LIU Day-Yang SHIEH Lon - Fon | 2005 | International Journal of Product Development2005，2，3： | 1 |
| 20 | Using default rates to model the term structure of credit risk显示文摘 | FONS J | 1994 | Financial Analysts Journal1994，，5： | 1 |
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