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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Predictors of Cognitive Dysfunction after Major Noncardiac Surgery显示文摘 | Terri G. Monk B Craig Weldon Cyndi W. Garvan Duane E. Dede Maria T. van der Aa Kenneth M. Heilman Joachim S. Gravenstein | 2008 | Anesthesiology2008，，1： | 5 |
| 3 | 慢性阻塞性肺疾病中黏液高分泌的潜在疗法显示文摘 | Jin-Ah Park Kenneth B Adler | 2006 | 中华医学杂志2006，86，41： | 4 |
| 4 | Evaluation of Burkholdderia cepacia strains:Root colonization of Catharanthus roseus and in vitro inhibition of selected of soil borne fungal pathogens 显示文摘 | Mansour B Martin A D Kenneth E C | 1999 | Proceedings of the Oklahoma Academy of Science1999，79，： | 3 |
| 5 | MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca^sup 2+^ overload and cell death显示文摘 | Aurora Arin B Mahmoud Ahmed I Luo Xiang Johnson Brett A van Rooij Eva Matsuzaki Satoshi Humphries Kenneth M Hill Joseph A Bassel-Duby Rhonda Sadek Hesham A Olson Eric N | 2012 | EN2012，，4： | 2 |
| 6 | Ankle Fractures in the Elderly: What You Get Depends on Where You Live and Who You See显示文摘 | Kenneth J Koval Jon Lurie Weiping Zhou Michael B Sparks Robert V Cantu Scott M Sporer James Weinstein | 2005 | Journal of Orthopaedic Trauma2005，，9： | 2 |
| 7 | Predictors of Cognitive Dysfunction after Major Noncardiac Surgery显示文摘 | Terri G. Monk B Craig Weldon Cyndi W. Garvan Duane E. Dede Maria T. van der Aa Kenneth M. Heilman Joachim S. Gravenstein | 2008 | Anesthesiology2008，，1： | 2 |
| 8 | Amyloid β-peptide impairs ion-motive ATPase activities:evidence for a role in loss of neuronal Ca^2+ Homeostasis and cell death显示文摘 | Robert J M Kenneth H Allan B | 1995 | J Neurosci1995，15，9： | 1 |
| 9 | Numerical Modeling of Concrete Confined by Fiber-Reinforced Composites显示文摘 | Malvar L J Kenneth B M John E C | 2004 | Journal of Composites for Construction2004，8，4： | 1 |
| 10 | Expressional alter- ations in functional ultra-conserved non-coding mas in re- sponse to all-trans retinoic acid-induced differentiation in neuroblastoma cells 显示文摘 | Karen M Kenneth B Niamh H | 2013 | BMC Cancer2013，13，： | 1 |
| 11 | 3D reconstruction of the carotid artery from two views using a single centerline显示文摘 | Kenneth R H Alan M W Peter B N | 2004 | International Congress Series2004，，： | 1 |
| 12 | A Recent Polyploidy Superim-posed on Older Large-Scale Duplications in the Arabidopsis Genome 显示文摘 | GUILLAUME B KARSTEN H KENNETH H W | 2003 | Genome Research2003，13，2： | 1 |
| 13 | Discounts and premium on closed-end mutual fund: a study in valuation 显示文摘 | Kenneth J B | 1973 | Journal of Finance1973，28，2： | 1 |
| 14 | The prognostic value of histology in the assessment of patients with Budd–Chiari syndrome显示文摘 | Thjon J Tang Kenneth P Batts Piet C de Groen Bart van Hoek Elizabeth B Haagsma Wim C.J Hop Harry L.A Janssen | 2001 | Journal of Hepatology2001，，3： | 1 |
| 15 | Fibroblast Growth Factor 23, Bone Mineral Density, and Risk of Hip Fracture Among Older Adults: The Cardiovascular Health Study显示文摘 | Anna Jovanovich Petra Bù?ková Michel Chonchol John Robbins Howard A. Fink Ian H. de Boer Bryan Kestenbaum Ronit Katz Laura Carbone Jennifer Lee Gail A. Laughlin Kenneth J. Mukamal Linda F. Fried Michael G. Shlipak Joachim H. Ix | 2013 | The Journal of Clinical Endocrinology & Metabolism2013，，8： | 1 |
| 16 | The Political Economy of Benefits and Costs : A Neoclassical Approach to Distributive Politics 显示文摘 | Weingast B Kenneth S Christopher J | 1981 | Journal of Political Economy1981，89，： | 1 |
| 17 | The measurement of responsibility in Children显示文摘 | Dale B Harris Kenneth E Clark Arnold M Rose Frances Valasek | 1954 | Child Development1954，25，1： | 1 |
| 18 | High-resolution image reconstruction from a sequence of rotated and translated frames and its application to an infrared imaging system显示文摘 | Russell C H Kenneth J B John G B | 1998 | Optical Engineering1998，37，1： | 1 |
| 19 | Kinetics and mechanisms of thermal decomposition of nitzoazomatic explosives显示文摘 | Brill B Kenneth J James | 1993 | Chemistry Review1993，93，： | 1 |
| 20 | Cyclic Hydroxamic Acids Derived from Indole显示文摘 | WILLIAM B WRIGHT Jr KENNETH H C | 1956 | J Am Chem Soc1956，78，： | 1 |
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