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| 1 | How severe is moderately severe acute pancreatitis? Clinical validation of revised 2012 Atlanta Classification显示文摘AIM To explore the outcomes and the appropriate treatment for patients with moderately severe acute pancreatitis(AP).METHODS Statistical analysis was performed on data from the prospectively collected database of 103 AP patients admitted to the Department of Surgery,Hospital of Lithuanian University of Health Sciences in 2008-2013. All patients were confirmed to have the diagnosis of AP during the first 24 h following admission. The severity of pancreatitis was assessed by MODS and APACHE Ⅱ scale. Clinical course was re-evaluated after 24,48 and 72 h. All patients were categorized into 3 groups based on Atlanta 2012 classification: Mild,moderately severe,and severe.Outcomes and management in moderately severe group were also compared to mild and severe cases according to Atlanta 1992 and 2012 classification.RESULTS Fifty-three-point four percent of patients had edematous while 46.6 % were diagnosed with necrotic AP. The most common cause of AP was alcohol(42.7%) followed by alimentary(26.2%),biliary(26.2%) and idiopathic(4.9%). Under Atlanta 1992 classification 56(54.4%) cases were classified as 'mild' and 47(45.6%) as 'severe'. Using the revised classification(Atlanta 2012),the patient stratification was different: 49(47.6%) mild,27(26.2%) moderately severe and 27(26.2%) severe AP cases. The two severe groups(Atlanta 1992 and Revised Atlanta 2012) did not show statistically significant differences in clinical parameters,including ICU stay,need for interventional treatment,infected pancreatic necrosis or mortality rates. The moderately severe group of 27 patients(according to Atlanta 2012) had significantly better outcomes when compared to those 47 patients classified as severe form of AP(according to Atlanta 1992) with lower incidence of necrosis and sepsis,lower APACHE Ⅱ(P = 0.002) and MODS(P = 0.001) scores,shorter ICU stay,decreased need for interventional and surgical treatment.CONCLUSION Study shows that Atlanta 2012 criteria are more accurate,reduce unnecessary treatments for patients with mild and moderate severe pancreatitis,potentially resulting in health costs savings. | Povilas Ignatavicius Aiste Gulla Karolis Cernauskis Giedrius Barauskas Zilvinas Dambrauskas | 2017 | World Journal of Gastroenterology2017，23，43： | 16 |
| 2 | Quantifying the thermal damping effect in underground vertical shafts using the nonlinear autoregressive with external input(NARX) algorithm显示文摘As air descends the intake shaft, its infrastructure, lining and the strata will emit heat during the night when the intake air is cool and, on the contrary, will absorb heat during the day when the temperature of the air becomes greater than that of the strata. This cyclic phenomenon, also known as the 'thermal damping effect' will continue throughout the year reducing the effect of surface air temperature variation. The objective of this paper is to quantify the thermal damping effect in vertical underground airways. A nonlinear autoregressive time series with external input(NARX) algorithm was used as a novel method to predict the dry-bulb temperature(Td) at the bottom of intake shafts as a function of surface air temperature. Analyses demonstrated that the artificial neural network(ANN) model could accurately predict the temperature at the bottom of a shaft. Furthermore, an attempt was made to quantify typical 'damping coefficient' for both production and ventilation shafts through simple linear regression models. Comparisons between the collected climatic data and the regression-based predictions show that a simple linear regression model provides an acceptable accuracy when predicting the Tdat the bottom of intake shafts. | Pedram Roghanchi Karoly C.Kocsis | 2019 | International Journal of Mining Science and Technology2019，29，2： | 8 |
| 3 | Pulmonary embolization as primary manifestation of hepatocellular carcinoma with intracardiac penetration: A case report显示文摘Intracardiac manifestation of hepatocellular carcinoma (HCC) is a rare condition and an uncommon finding even at autopsy. Pulmonary tumor embolism as a presenting feature of HCC has been published only twice previously.In our case report, a 63-year-old man presented with high fever and six episodes of recurrent pneumonias during the last half year. Echocardiography was performed, a solid mass was found in the right atrium. Transesophageal echocardiography proved a tumor mass in the inferior vena cava (ⅣC) extending into the right atrium, abdominal ultrasound revealed tumor mass in the ⅣC and a solid tumor in the liver. Combined liver and heart surgery was attempted in order to remove the tumor mass from both the liver and the right atrium. Acute cor pulmonale occurred during tumor removal from the right atrium and the patient expired. In addition to local factors the possibility of embolization should arise in the background of recurrent pneumonia. Occult carcinoma must be included in possible causes of recurrent pulmonary embolism. Searching for primary malignancy should include HCC as frequent cause of hypercoagulability. In case of HCC, echocardiography is suggested because of the possibility of expansion in MC or right atrium and tumor-embolization. | Elod Papp Zsuzsanna Keszthelyi Nagy Karoly Kalmar Lajos Papp Csaba Weninger Tamas Tornoczky Endre Kalman Kalman Toth Tamas Habon | 2005 | World Journal of Gastroenterology2005，11，15： | 4 |
| 4 | Dual-color deep-tissue three-photon microscopy with a multiband infrared laser显示文摘Multiphoton microscopy combined with genetically encoded fluorescent indicators is a central tool in biology.Threephoton(3P)microscopy with excitation in the short-wavelength infrared(SWIR)water transparency bands at 1.3 and 1.7μm opens up new opportunities for deep-tissue imaging.However,novel strategies are needed to enable in-depth multicolor fluorescence imaging and fully develop such an imaging approach.Here,we report on a novel multiband SWIR source that simultaneously emits ultrashort pulses at 1.3 and 1.7μm that has characteristics optimized for 3P microscopy:sub-70 fs duration,1.25 MHz repetition rate,and μJ-range pulse energy.In turn,we achieve simultaneous 3P excitation of green fluorescent protein(GFP)and red fluorescent proteins(mRFP,mCherry,tdTomato)along with third-harmonic generation.We demonstrate in-depth dual-color 3P imaging in a fixed mouse brain,chick embryo spinal cord,and live adult zebrafish brain,with an improved signal-to-background ratio compared to multicolor twophoton imaging.This development opens the way towards multiparametric imaging deep within scattering tissues. | Khmaies Guesmi Lamiae Abdeladim Samuel Tozer Pierre Mahou Takuma Kumamoto Karolis Jurkus Philippe Rigaud Karine Loulier Nicolas Dray Patrick Georges Marc Hanna Jean Livet Willy Supatto Emmanuel Beaurepaire Frédéric Druon | 2018 | Light(Science & Applications)2018，7，1： | 3 |
| 5 | Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I–II colon cancer patients显示文摘 | Wilma E. Mesker Gerrit-Jan Liefers Jan M.C. Junggeburt Gabi W. van Pelt Paola Alberici Peter J.K. Kuppen Noel F. Miranda Karin A.M. van Leeuwen Hans Morreau Karoly Szuhai Rob A.E.M. Tollenaar Hans J. Tanke | 2009 | Cellular Oncology2009，，3： | 2 |
| 6 | TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β显示文摘 | Motozo Yamashita Karoly Fatyol Chaoyang Jin Xiangchun Wang Zhenggang Liu Ying E. Zhang | 2008 | Molecular Cell2008，，6： | 2 |
| 7 | The measurement of clinical pain intersity:a comparision of six methods Pain显示文摘 | Jensen MP Karoly P Braver S | 1986 | 1986，，： | 1 |
| 8 | The measurement of clinical pain in- tensity:a comparison of six methods 显示文摘 | Jensen MP Karoly P Braver S | 1986 | Pain1986，27，1： | 1 |
| 9 | Licofelone Modulates Neuroinflammation and Attenuates Mechanical Hypersensitivity in the Chronic Phase of Spinal Cord Injury 显示文摘 | DULIN J N KAROLY E D WANG Y | 2013 | Journal of neuro- science2013，33，2： | 1 |
| 10 | The measurement of clinical pain intensity: a comparison of six methods显示文摘 | Jensen iMP Karoly P Braver S | 1986 | Pain1986，27，1： | 1 |
| 11 | Long-term grazing effects on genetic variation in Idaho fescue 显示文摘 | MATLAGA D KAROLY K | 2004 | Range Manage2004，57，： | 1 |
| 12 | Wear Simulation of a Reciprocating Seal显示文摘 | Nandor Bekesi Karoly Varadi David Felhos | 2011 | Journal of Tri?bology2011，133，03： | 1 |
| 13 | Production of glass-ceramics from fly ash using arc plasma 显示文摘 | Karoly Z Mohai I Toth M | 2007 | Journal of the European Ceramic Society2007，27，2： | 1 |
| 14 | The measurement of clinical pain intensity : a comparison of six methods 显示文摘 | Jensen MP Karoly P Braver S | 1986 | Pain1986，27，1： | 1 |
| 15 | The measurement of clinical pain intensity:a comparison of six methods 显示文摘 | Jensen M P Karoly P Braver S | 1986 | Pain1986，27，1： | 1 |
| 16 | The measurement of clinic pain inten- sity : a comparison of six methods 显示文摘 | Jensen MP Karoly P Braver S | 1986 | Pain1986，27，1： | 1 |
| 17 | Attributing physical and biological impacts to anthropogenic climate change显示文摘 | ROSENZWEIG C KAROLY D VICARELLI M | 2008 | Nature2008，453，： | 1 |
| 18 | The measurement of clinical pain intensity: a comparison of six methods 显示文摘 | Jensen MP Karoly P Braver S | 1986 | Pain1986，27，： | 1 |
| 19 | The measurement of clinical pain intensity: acomparison of six methods 显示文摘 | JensenMP Karoly P Braver S | 1986 | Pain1986，27，： | 1 |
| 20 | Up-regulation of tissue factor in human pulmonary artery endothelial ceils after ultrafine particle exposure 显示文摘 | Karoly ED Li Z Dailey LA | 2007 | Environ Health Perspect2007，115，： | 1 |
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