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| 1 | Changing organ allocation policy for kidney transplantation in the United States显示文摘The new kidney allocation scheme(KAS) in effect since December 4th 2014 was designed to overcome the shortcomings of previous system. A key feature of the new KAS is preferential allocation of best quality organs to wait-list candidates with the longest predictivesurvival in a concept called longevity matching. Highly sensitized recipients would get extra points and enjoy widespread sharing of organs in order to increase accessibility to transplant. Wait-list candidates with blood group B will be offered organs from donors with A2 and A2 B blood type in order to shorten their wait-list time. Time on the wait list will start from day of listing or date of initiation of dialysis whichever comes first which should benefit candidates with limited resources who might be late to get on the transplant list. Pay back system has been eliminated in the new KAS. These changes in organ allocation policy may lead to increase in median half-life of the allograft and increase the number of transplants; thus resulting in better utilization of a scarce resource. There could be unintended negative consequences which may become evident over time. | Bhavna Chopra Kalathil K Sureshkumar | 2015 | World Journal of Transplantation2015，5，2： | 4 |
| 2 | Comparative evaluation of frictional forces in active and passive self-ligating brackets with various archwire alloys显示文摘 | Krishnan M Kalathil S Abraham KM | 2009 | Am J Orthod Dentofacial Orthop2009，136，5： | 1 |
| 3 | Ultrasonically controlled release and targeted delivery of diclofenac sodium via gelatin magnetic microspheres显示文摘 | Muniyandy Saravanan Kesavan Bhaskar Gomathinayagam Maharajan Kalathil Sadasivan Pillai | 2004 | International Journal of Pharmaceutics2004，，1： | 1 |
| 4 | Role of steroid maintenance in sensitized kidney transplant recipients显示文摘AIM: To evaluate whether there is a threshold sensitization level beyond which benefits of chronic steroid maintenance(CSM) emerge. METHODS: Using Organ Procurement and Transplant Network/United Network of Organ Sharing database, we compared the adjusted graft and patient survivals for CSM vs early steroid withdrawal(ESW) among patients who underwent deceased-donor kidney(DDK) transplantation from 2000 to 2008 who were stratified by peak-panel reactive antibody(peak-PRA) titers(0%-30%, 31%-60% and > 60%). All patients received perioperative induction therapy and maintenance immunosuppression based on calcineurin inhibitor(CNI) and mycophenolate mofetil(MMF).RESULTS: The study included 42851 patients. In the 0%-30% peak-PRA class, adjusted over-all graft-failure(HR 1.11, 95%CI: 1.03-1.20, P = 0.009) and patientdeath(HR 1.29, 95%CI: 1.16-1.43, P < 0.001) risks were higher and death-censored graft-failure risk(HR 1.06, 95%CI: 0.98-1.14, P = 0.16) similar for CSM(n = 25218) vs ESW(n = 7399). Over-all(HR 1.04, 95%CI: 0.85-1.28, P = 0.70) and death-censored(HR 0.97, 95%CI: 0.78-1.21, P = 0.81) graft-failure risks were similar and patient-death risk(HR 1.39, 95%CI: 1.03-1.87, P = 0.03) higher for CSM(n = 3495) vs ESW(n = 850) groups for 31%-60% peak-PRA class. In the > 60% peak-PRA class, adjusted overall graft-failure(HR 0.90, 95%CI: 0.76-1.08, P = 0.25) and patientdeath(HR 0.92, 95%CI: 0.71-1.17, P = 0.47) risks were similar and death-censored graft-failure risk lower(HR 0.84, 95%CI: 0.71-0.99, P = 0.04) for CSM(n = 4966)vs ESW(n = 923).CONCLUSION: In DDK transplant recipients who underwent perioperative induction and CNI/MMF maintenance, CSM appears to be associated with increased risk for death with functioning graft in minimally-sensitized patients and improved death-censored graft survival in highly-sensitized patients. | Kalathil K Sureshkumar Richard J Marcus Bhavna Chopra | 2015 | World Journal of Transplantation2015，5，3： | 1 |
| 5 | Comparative eva- luation of frictional forces in active and passive self-h- gating brackets with various archwire alloys显示文摘 | Krishnan M Kalathil S Abraham KM | 2009 | Am J Or- thod Dentofacial Orthop2009，136，5： | 1 |
| 6 | Elastic fiber-associated proteins of skin in development and photoaging显示文摘 | WERTH VP KALATHIL SE JAWORSKY C | | 0，，： | 1 |
| 7 | T-regulatory cells and programmed death 1+T cells contribute to effector T-cell dysfunction in patients with chronic obstructive pulmonary disease显示文摘 | Kalathil SG Lugade AA Pradhan V | 2014 | Am J Crit Care Med2014，190，1： | 1 |
| 8 | Granular activated carbon based microbial fuel cell for simultaneous decolorization of real dye wastewater and electricity generation 显示文摘 | Kalathil S Lee J Cho M H | 2011 | New Biotechnology2011，29，1： | 1 |
| 9 | Production of bioelectricity, biohydrogen, high value chemicals and bioinspired nanomaterials by electrochemically active biofilms 显示文摘 | Kalathil S Khan MM Lee J Cho MH | 2013 | Biotechnol Adv2013，31，6： | 1 |
| 10 | Superiority of Pediatric En Bloc Renal Allografts Over Living Donor Kidneys: A Long-term Functional Study显示文摘 | Kalathil K. Sureshkumar Chandana S. Reddy Dai D. Nghiem Stephen E. Sandroni Barbara J. Carpenter | 2006 | Transplantation2006，，3： | 1 |
| 11 | Comparative evaluation of frictional forces in active and passive self-ligating brack- etswith various archwire alloys 显示文摘 | Krishnan M Kalathil S Abraham KM | 2009 | Am J Orthod Dentofacial Or- thop2009，136，5： | 1 |
| 12 | Comparative evaluation of frictional forces in active and passive self-ligating brackets with various archwire alloys显示文摘 | Manu Krishnan Sukumaran Kalathil Kurian Mathew Abraham | 2009 | American Journal of Orthodontics & Dentofacial Orthopedics2009，，5： | 1 |
| 13 | Granular activated carbon based micro-bial fuel cell for simultaneous decolorization of real dye wastewater and electricity generation显示文摘 | Kalathil S Lee J Cho M H | 2011 | New Biotechnology2011，29，1： | 1 |
| 14 | Comparative evaluation offrictional forces in active and passive self-ligating brackets with va-rious archwire alloys显示文摘 | Krishnan M Kalathil S Abraham KM | 2009 | Am J Orthod Dentofacial Orthop2009，136，5： | 1 |
| 15 | Metformin,B12 and homocysteine levels:the plausible cause or effect? 显示文摘 | Musarrat K Kalathil D Varughese GI | 2008 | Formos Med Assoc2008，107，6： | 1 |
| 16 | Kidney transplantation in older recipients:Preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage显示文摘AIM To evaluate the outcomes of transplanting marginal kidneys preemptively compared to better-quality kidneys after varying dialysis vintage in older recipients.METHODS Using OPTN/United Network for Organ Sharing database from 2001-2015, we identified deceased donor kidney(DDK) transplant recipients > 60 years of age who either underwent preemptive transplantation of kidneys with kidney donor profile index(KDPI) ≥ 85%(marginal kidneys) or received kidneys with KDPI of 35%-84%(better quality kidneys that older wait-listed patients would likely receive if waited longer) after being on dialysis for either 1-4 or 4-8 years. Using a multivariate Cox model adjusting for donor, recipient and transplant related factors-overall and death-censored graft failure risks along with patient death risk of preemptive transplant recipients were compared to transplant recipients in the 1-4 and 4-8 year dialysis vintage groups.RESUTLS The median follow up for the whole group was 37 mo(interquartile range of 57 mo). A total of 6110 DDK transplant recipients above the age of 60 years identified during the study period were found to be eligible to be included in the analysis. Among these patients350 received preemptive transplantation of kidneys with KDPI ≥ 85. The remaining patients underwent transplantation of better quality kidneys with KDPI 35-84% after being on maintenance dialysis for either 1-4 years(n = 3300) or 4-8 years(n = 2460). Adjusted overall graft failure risk and death-censored graft failure risk in preemptive high KDPI kidney recipients were similar when compared to group that received lower KDPI kidney after being on maintenance dialysis for either 1-4 years(HR 1.01, 95%CI: 0.90-1.14, P = 0.84 and HR 0.96, 95%CI: 0.79-1.16, P = 0.66 respectively) or 4-8 years(HR 0.82, 95%CI: 0.63-1.07, P = 0.15 and HR 0.81, 95%CI: 0.52-1.25, P = 0.33 respectively). Adjusted patient death risk in preemptive high KDPI kidney recipients were similar when compared to groups that received lower KDPI kidney after being on maintenance dialysis for 1-4 years(HR 0.99, 95%CI: 0.87-1.12, P = 0.89) but lower compared to patients who were on dialysis for 4-8 years(HR 0.74, 95%CI: 0.56-0.98, P = 0.037).CONCLUSION In summary, our study supports accepting a 'marginal' quality high KDPI kidney preemptively in older waitlisted patients thus avoiding dialysis exposure. | Bhavna Chopra Kalathil K Sureshkumar | 2018 | World Journal of Transplantation2018，8，4： | 1 |
| 17 | Comparative evaluation of frictional forces in active and passive self- ligating brackets with various archwire alloys显示文摘 | Krishnan M Kalathil S Abraham KM | 2009 | Am J Orthod Dentofacial Orthop2009，136，5： | 1 |
| 18 | Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy 显示文摘 | Kalathil KS | 2008 | Vascular Health Risk Management2008，4，6： | 1 |
| 19 | Metformin, B12 and homo cysteine levels: the plausible cause or effect显示文摘 | Musarrat K Kalathil Varughese GI | 2008 | J Formos Med As soc2008，107，6： | 1 |
| 20 | Higher frequencies of GARP+CTLA-4+Foxp3+T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T cell functionality显示文摘 | Kalathil S Lugade AA Miller A | 2013 | Cancer Res2013，73，8： | 1 |
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