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| 1 | Effects of endoscopic sphincterotomy on biliary epithelium:A case-control study显示文摘AIM: To study the long-term effects of endoscopic sphincterotomy on biliary epithelium. METHODS: This is a prospective case-control study. A total of 25 patients with a median age of 71 years (range 49-89 years) and prior endoscopic sphincterotomy (ES) for benign disease formed the fi rst group. The median time from ES was 42 mo (range 8-144 mo). Another 25 patients with a median age of 76 years (range 44-94 mo) and similar characteristics who underwent current endoscopic retrograde cholangio-pancreatography (ERCP) and ES for benign disease formed the second group (control group). Brush cytology of the biliary tree with p53 immunocytology was performed in all patients of both groups. ERCPs and recruitment were conducted at the Endoscopic Unit of Aretaieion University Hospital and Tzaneio Hospital, Athens, from October 2006 to June 2010. RESULTS: No cases were positive or suspicious for malignancy. Epithelial atypia was higher in the first group (32% vs 8% in the second group, P = 0.034). Acute cholangitis and previous biliary operation rates were also higher in the fi rst group (acute cholangitis, 60% vs 24% in the second group, P = 0.01; previous biliary operation, 76% vs 24% in the second group, P = 0.001). Subgroup analysis showed that previous ES was the main causal factor for atypia, which was not related to the time interval from the ES (P = 0.407). Two patients (8%) with atypia in the fi rst group were p53-positive. CONCLUSION: ES causes biliary epithelial atypia that represents mostly reactive/proliferative rather than premalignant changes. The role of p53 immunoreactivity in biliary atypia needs to be further studied. | John Kalaitzis Antonios Vezakis George Fragulidis Irene Anagnostopoulou Spyros Rizos Efstathios Papalambros Andreas Polydorou | 2012 | World Journal of Gastroenterology2012，18，8： | 3 |
| 2 | Monitoring Greenhouses Gases over China Using Space-Based Observations Monitoring Greenhouses Gases over China Using Space-Based Observations显示文摘The atmospheric carbon dioxide(CO 2)concentration has increased to more than 405 parts per million(ppm.1 ppm=10-6 m/s 2)in 2017 due to human activities such as deforestation,land-use change and burning of fossil fuels.Although there is broad scientific consensus on the damaging consequences of the change in climate associated with increasing concentrations of greenhouse gases,fossil CO 2 emissions have continued to increase in recent years mainly from rapidly developing economies and China is now the largest emitter of CO 2 generating about 30%of all emissions globally.To allow more reliable forecast of the future state of the carbon cycle and to support the efforts for mitigation greenhouse gas emissions,a better understanding of the global and regional carbon budget is needed.Space-based measurements of CO 2 can provide the necessary observations with dense coverage and sampling to provide improved constrains on of carbon fluxes and emissions.The Chinese Global Carbon Dioxide Monitoring Scientific Experimental Satellite(TanSat)was established by the National High Technology Research and Development Program of China with the main objective of monitoring atmospheric CO 2 and CO 2 fluxes at the regional and global scale.TanSat has been successfully launched in December 2016 and as part of the Dragon programme of ESA and the Ministry of Science and Technology(MOST),a team of researchers from Europe(UK and Finland)and China has evaluated early TanSat data and contrast it against data from the GOSAT mission and models.In this manuscript,we report on retrieval intercomparisons of TanSat data using two different retrieval algorithms,on validation efforts for the Eastern Asia region using GOSAT CO 2 data and first assessments of TanSat and GOSAT CO 2 data against model calculations using the GEOS-Chem model. | Hartmut BOESCH Yi LIU Paul I PALMER Johanna TAMMINEN Jasdeep S ANAND Zhaonan CAI Ke CHE Huilin CHEN Xi CHEN Liang FENG Janne HAKKARAINEN Pauli HEIKKINEN Nikoleta KALAITZI Rigel KIVI Robert PARKER Peter SOMKUTI Jing WANG Alex WEBB Dongxu YANG Lu YAO You YI | 2020 | Journal of Geodesy and Geoinformation Science2020，3，4： | 2 |
| 3 | Exploiting marine actinomycete biosynthetic pathways for drug discovery显示文摘 | Moore BS Kalaitzis JA Xiang LK | 2005 | Antonie Van Leeuwenhoek2005，87，1： | 1 |
| 4 | Ureteroscopic laser treatment of upper urinary tract urothelial cellcarcinomas: can a tumour free status be achieved?显示文摘 | KALAITZIS C ZISIMOPOULOS A GIANNAKOPOULOS S | 2013 | Adv Urol2013，2013，42： | 1 |
| 5 | Biosynthesis and structural revision of neomarinone 显示文摘 | Kalaitzis J A Hamano Y Nilsen G | 2003 | Org Lett2003，5，23： | 1 |
| 6 | Holmium laser lithothripsy of ureteral calculi : our initial experience 显示文摘 | Triantafyllidis A Kalaitzis C Giannakopoulos S | 2007 | Urol Int2007，79，1： | 1 |
| 7 | Combined brief psychosexual intervention after mastectomy : effects on sexuality, body image, and psychological well-being 显示文摘 | Kalaitzi C Papadopoulos VP Michas K | 2007 | J Snrg Oncol2007，96，3： | 1 |
| 8 | AFLP reveals structural details of genetic diversity within cultivated olive germplasm from the Eastern Mediterranean显示文摘 | Carolyn A. Owen Elena-Craita Bita Georgios Banilas Shady E. Hajjar Vardis Sellianakis Uygun Aksoy Serra Hepaksoy Rony Chamoun Salma N. Talhook Ioannis Metzidakis Polydefkis Hatzopoulos Panagiotis Kalaitzis | 2005 | Theoretical and Applied Genetics2005，，7： | 1 |
| 9 | Exploitingmarine actinomycete biosynthetic pathways fordrug discovery 显示文摘 | MOORE B S KALAITZIS J A XIANG L K | 2005 | Antonie van Leeuwen-hoek2005，87，： | 1 |
| 10 | EncM,a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement,aldol condensation,and heterocycle-forming reactions显示文摘 | Xiang L Kalaitzis J A Moore B S | | 0，，： | 1 |
| 11 | Molecular characterization of a tomato endo-β-1,4-glucanase gene expressed in mature pistils,abscission zones and fruit显示文摘 | KALAITZIS P HONG S SOLOMOS T | 1999 | Plant and Cell Physiology1999，40，8： | 1 |
| 12 | The Mrna for an ETR1 homologue in tomato is constitutively expressed in vegetative and reproductive tissues显示文摘 | ZHOU D KALAITZIS P MATrOO A K | 1996 | Plant MolBiol1996，30，： | 1 |
| 13 | Exploiting marine actinomycete biosynthetic pathways for drug discovery显示文摘 | Moore B S Kalaitzis J A Xiang L K | 2005 | Antonie van Leeuwenhoek2005，87，： | 1 |
| 14 | Cloning of a tomato polygalacturonase expressed in abscission显示文摘 | Panagiotis Kalaitzis Susan M. Koehler Mark L. Tucker | 1995 | Plant Molecular Biology1995，，4： | 1 |
| 15 | Holmium laser lithothfipsy of ureteral calculi: our initial experience 显示文摘 | Triantafyllidis A Kalaitzis C Giarmakopoulos S | 2007 | Urol Int2007，79，1： | 1 |
| 16 | The mRNA for an ETR1 homologue in tomato is constitutively expresse d in vegetative and reproductive tissues 显示文摘 | Zhou D B Kalaitzis P Mattoo A K | 1996 | Plant Molecular Biology1996，30，： | 1 |
| 17 | Differential induction of phenylalanine ammonia-lyase in response to ripening and wounding in muskmelon fruit显示文摘 | Kanellis A K Diallinas G Kalaitzis P | | 0，，01： | 1 |
| 18 | Cellulase occurs in multiple active forms in ripe avocado fruit mesocarp显示文摘 | Kanelis A K Kalaitzis P | 1992 | Plant Physiol1992，98，： | 1 |
| 19 | Three different polygalacturonases are expressed in tomato leaf and flower abscission,each with a different temporal expression pattern显示文摘 | Kalaitzis P Solomos T Tucker ML | 1997 | Plant Physiol1997，113，： | 1 |
| 20 | Holmium laser lithothripsy of ureteral calculi: our initial experience显示文摘 | Triantafyllidis A Kalaitzis C Giannakopoulos S | 2007 | Urol Int2007，79，1： | 1 |
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