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| 1 | 0Adipose-derived stem cells: Implications in tissue regeneration显示文摘Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration. | Wakako Tsuji J Peter Rubin Kacey G Marra | 2014 | World Journal of Stem Cells2014,6,3: | 19 |
| 2 | 提升全球工程教育研究能力(AGCEER):建立研究与实践、政策和工业的关联显示文摘【背景】我们的报告源于欧洲工程教育杂志和美国工程教育杂志联合倡导的提升全球工程教育研究能力(AGCEER)的活动。确切地说,我们呈现给各位的研究结果,来自2007年7月至2008年12月间举行的一系列国际工程教育会议,期间参会者提出并讨论了工程教育研究的现状和未来趋势。【目的(假设)】AGCEER会议参加者如何描述:(1)工程教育研究和教育实践、政策思考、工业之间的关系;(2)重要的利益相关者、机制/战略,以及建立研究与实践、政策和工业关联所面临的挑战。【设计/方法】主题词分析法被用于分类和解读十场涉及六大洲、300位参会者的AGCEER会议的文本数据,包括会议记录和笔记等。一个开放的编码程序被用于捕获每次会议中有关研究与实践、政策和工业关联的话题。【结果】我们发现,AGCEER与会者经常讨论工程教育研究需要与工程教学实践相联系,并对此有广泛共识。关于建立研究与政策及工业联系的讨论仍在起步阶段,却开始受到关注。【结论】我们提出一个循环模式,可望更好地构想工程教育研究如何能够跨越区域和全球的背景,战略性地与实践、专业和工业相联系。 | Brent K. Jesiek Maura Borrego Kacey Beddoes 孔寒冰(翻译) 王沛民(校订) 高彦鸣(校订) 李昕(校订) | 2010 | 高等工程教育研究2010,58,3: | 3 |
| 3 | 用于脂肪移植及脂肪干细胞分离获取与处理技术的对比显示文摘背景与目的脂肪获取和处理技术的差异可能会影响脂肪移植的成功率。本研究利用裸鼠模型,对比不同处理方法获取的脂肪移植物的性质,并评估移植脂肪组织中存活组织的体积。方法第一阶段,通过负压吸引辅助脂肪抽吸或超声辅助脂肪抽吸2种方式获取脂肪,并利用2种孔隙尺寸的筛网进行过滤。对移植材料的如下方面进行分析:平均团块大小,油脂、脂肪和水溶性成分的构成比,以及基质血管细胞群(stromalvascularfraction,SVF)的产量。将过滤物及滤液注入无胸腺的裸鼠皮下。第二阶段,将仅通过负压吸引吸脂术中获取脂肪抽吸物,进行离心、纱布摇匀或过滤处理,然后利用相似的规范进行研究。结果与负压吸引脂肪抽吸术相比,超声辅助的脂肪抽吸术获取的脂肪在SVF含量和脂肪移植体内研究成活量情况均相似。通过超声辅助的脂肪抽吸术仅比负压脂肪抽吸术产生稍微多的油脂;通过500μm或800μm孔径的滤网进行过滤均可有效去除液体和油脂。利用纱布法处理的脂肪,其体内移植成活率和SVF产量均最高。对所有移植物的组织学分析均显示为完整的脂肪组织。结论通过超声辅助及负压吸引行脂肪抽吸术获取的脂肪,其在异种移植模型中具有相似的成活率。对于少量填充移植而要求最佳成活率的身体敏感区域而言,利用纱布摇匀的处理方式可能是用于美容性脂肪移植的最佳方法。过滤法和离心法均可有效去除液体成分,其处理过的脂肪具有相似的移植成活率,当所需移植体积较大时,这2种方法均可行。 | Christine Fisher Tara L. Grahovac Mark E. Schafer Ron D. Shippert Kacey G. Marra J. Peter Rubin 魏峰 高景恒 张晨 | 2014 | 中国美容整形外科杂志2014,25,4: | 2 |
| 4 | The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial det'ects显示文摘 | Jason R Dudas BA Kacey G | 2006 | J Ann Plast Surg2006,56,5: | 1 |
| 5 | 气候与登革热传播:证据与启示显示文摘[背景]气候通过矢量动力学、药物研发和蚊子/人类的相互作用而影响登革热的生态。虽然人们已认识到这些关系,但是气候变化对传播途径的影响尚不清楚。研究人员采用气候驱动统计模型和基于过程的模型,来完善这些关系的知识,并预测气候变化对登革热发生的影响,但得到的结果却并不一致。[目的]明确气候对登革热病毒生态学的主要影响,并评估以气候为基础的登革热模型在描述气候和登革热之间关联、模拟疫情并预测气候变化方面的能力。[方法]回顾实验室研究、现场研究和统计学分析中有关气候与登革热之间直接和间接关联的证据,这些研究均涉及虫媒、登革热发病率和气候条件之间关联。评估以气候为驱动因子、基于过程的登革热模型的潜在作用,并提出建议以提高其性能。[结果和讨论]气候变量与影响登革热传播的因素之间具有复杂的关系。一个气候变量可能通过该系统的一个方面增强登革热的潜在传播力,同时又通过该系统的另一个方面减弱这种潜在的传播力。这种复杂性至少可以部分解释登革热与气候之间在统计学关联上的不一致性。基于过程的模型能够解释复杂的动力学,但往往忽略登革热生态的重要方面,特别是病毒形成与宿主-物种的相互作用。[结论]整合并应用现有的关于气候对登革热病毒生态各方面影响的知识,将有助于指引今后的研究,并促进更有效地预测气候变化对登革热发病的影响。 | Cory W. Morin Andrew C. Comrie Kacey Ernst | 2014 | 环境与职业医学2014,31,2: | 1 |
| 6 | The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects显示文摘 | Jason R Dudas BA Kacey G | 2006 | Ann Plastic Surg2006,56,5: | 1 |
| 7 | Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health显示文摘According to the classic 'diet-heart' hypothesis, high dietary intake of saturated fats and cholesterol combined with low intake of polyunsaturated fats can increase levels of serum cholesterol and lead to the development of atherogenic plaques and ultimately cardiovascular diseases. Recently, the beneficial health effects of omega-6 polyunsaturated fatty acids, particularly linoleic acid (LA), on cardiovascular health have been called into question with some scientists suggesting that consumption of LA should be reduced in Western countries. The focus of this critical review is on the controversy surrounding the effects of dietary intake of LA on cardiovascular health. Specifically, we critically examined the effects of both unadulterated and adulterated forms of LA on cardiovascular health outcomes based on findings from epidemiological studies and randomized controlled trials. Additionally, we address common concerns surrounding dietary intake of LA regarding its relationship with arachidonic acid, the ratio of omega-6 to omega-3 fatty acids, and its relationship with inflammation. Our critical review indicates that unadulterated forms of LA are cardioprotective and should be consumed as part of a healthy diet. In contrast, abundant evidence now indicates that adulterated forms of LA, predominantly hydrogenated vegetable oils, are atherogenic and should not be considered part of a healthy diet. The ability to adulterate the natural omega-6 fatty acid, LA, has contributed to mixed findings regarding the effects of this fatty acid on cardiovascular health. Thus, it is critical that the source of LA be taken into account when drawing conclusions about the physiological effects of this fatty acid. The findings of the present review are in line with current dietary recommendations of the American Heart Association. | Stephen D. Anton Kacey Heekin Carrah Simkins Andres Acosta | 2013 | Journal of Integrative Medicine2013,11,1: | 1 |
| 8 | Inorganic phosphate-solubilization by two penicillium species in solution cultureand soil显示文摘 | Asea P E A Kacey R M Sterart J W B | 1988 | Soilbio&Biochem1988,20,4: | 1 |
| 9 | Injectable Silk Foams for Soft Tissue Regeneration显示文摘 | Evangelia Bellas Tim J. Lo Eric P. Fournier Joseph E. Brown Rosalyn D. Abbott Eun S. Gil Kacey G. Marra J. Peter Rubin Gary G. Leisk David L. Kaplan | 2015 | Adv. Healthcare Mater2015,,3: | 1 |
| 10 | Polarimetric imaging of crystals显示文摘 | Werner Kaminsky Kacey Claborn Bart Kahr | 2004 | ChemSocRev2004,33,8: | 1 |
| 11 | Bioreactors addressing diabetes mellitus 显示文摘 | Danielle M M Jorg C G Kacey G M | 2014 | J Diabetes Sei Technol2014,8,10: | 1 |
| 12 | Restoration of Longitudinal Forearm Stability Using a Suture Button Construct显示文摘 | Matthew L. Drake Gerald L. Farber Kacey L. White Brent G. Parks Keith A. Segalman | 2010 | Journal of Hand Surgery2010,,12: | 1 |
| 13 | The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects显示文摘 | Jason R Dudas B A Kacey G | 2006 | Ann Plast Surg2006,56,5: | 1 |
| 14 | Pigmentation PAX‐ways: the role of Pax3 in melanogenesis, melanocyte stem cell maintenance, and disease显示文摘 | Jennifer D.Kubic Kacey P.Young Rebecca S.Plummer Anton E.Ludvik DeborahLang | 2008 | Pigment Cell & Melanoma Research2008,,6: | 1 |
| 15 | 显示文摘 | Daiwon Choi Kacey G Marra Prashant N Kumta | 2004 | Materials Research Bulletin2004,39,: | 1 |
| 16 | Laparoscopic sacral colpopexy versus total vaginal mesh for vaginal vault prolapse: a randomized trial显示文摘 | Christopher F. Maher Benjamin Feiner Eva M. DeCuyper Cathy J. Nichlos Kacey V. Hickey Peter O’Rourke | 2011 | American Journal of Obstetrics and Gynecology2011,,4: | 1 |
| 17 | Role of Gender and Anatomical Region on Induction of Osteogenic Differentiation of Human Adipose-derived Stem Cells显示文摘 | A Emre Aksu J Peter Rubin Jason R. Dudas Kacey G. Marra | 2008 | Annals of Plastic Surgery2008,,3: | 1 |
| 18 | A systematic review of randomized controlled trials examining the effectiveness of saffron(Crocus sativus L.) on psychological and behavioral outcomes显示文摘BACKGROUND:Throughout the past three decades,increased scientifi c attention has been given to examining saffron’s(Crocus sativus L.)use as a potential therapeutic or preventive agent for a number of health conditions,including cancer,cardiovascular disease,and depression.OBJECTIVE:The purpose of this systematic review is to examine and categorize the current state of scientifi c evidence from randomized controlled trials(RCTs)regarding the effi cacy of saffron on psychological/behavioral outcomes.SEARCH STRATEGY:Electronic and non-electronic systematic searches were conducted to identify all relevant human clinical research on saffron.The search strategy was extensive and was designed according to the'Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA).'Reference lists of articles that met the inclusion criteria were searched.Only English language studies were reviewed.INCLUSION CRITERIA:Saffron trials in combination with other substances and saffron safety studies were considered,in accordance with the PRISMA statement.Included studies must have a control group.Included studies must measure a physiological and/or a behavioral outcome.DATA EXTRACTION AND ANALYSIS:The methodological quality of all included studies was independently evaluated by two reviewers using the Jadad score.Mean scores and P-values of measures were compared both inter-and intra-study for each parameter(i.e.,depression).RESULTS:Twelve studies met our inclusion criteria.These studies examined the effects of saffron on psychological/behavioral outcomes of:major depressive disorder(n=6),premenstrual syndrome(n=1),sexual dysfunction and infertility(n=4),and weight loss/snacking behaviors(n=1).The data from these studies support the effi cacy of saffron as compared to placebo in improving the following conditions:depressive symptoms(compared to anti-depressants and placebo),premenstrual symptoms,and sexual dysfunction.In addition,saffron use was also effective in reducing excessive snacking behavior.CONCLUSION:Findings from initial clinical trials suggest that saffron may improve the symptoms and the effects of depression,premenstrual syndrome,sexual dysfunction and infertility,and excessive snacking behaviors.Larger multi-site clinical trials are needed to extend these preliminary fi ndings. | Heather Ann Hausenblas Kacey Heekin Heather Lee Mutchie Stephen Anton | 2015 | Journal of Integrative Medicine2015,13,4: | 1 |
| 19 | Adipogenic Potential of Adipose Stem Cell Subpopulations显示文摘 | Han Li Ludovic Zimmerlin Kacey G. Marra Vera S. Donnenberg Albert D. Donnenberg J. Peter Rubin | 2011 | Plastic and Reconstructive Surgery2011,,3: | 1 |
| 20 | 让梦想漂流的艺术家显示文摘生活往现代大都市,我们都在流动,我们都在飘泊,我们都没有根,我们都对自己身处的城市欠缺归属感。某天,有人发现在香港维港上漂流着一间小房子,房子主人黄国才不是在求救,他是在寻梦,寻一个飘泊流动的艺术梦想。 | Joel Leung Kacey Wong | 2011 | 汽车生活2011,,11: | 0 |