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| 1 | Early tectonic uplift of the northern Tibetan Plateau显示文摘The Hexi Corridor is the northmost foreland basin of the Tibetan Plateau and its formation is controlled by the northern marginal fault of Tibet, Altyn Tagh Fault (ATF)-North Qilian Shan marginal Fault (NQF), and the southern Kuantan Shan-Longshou Shan Fault (KLF). So its study is important to understanding the mechanism of Tibet formation and its influence on global climate change. The oldest Cenozoic sediments in the Corridor is the Huoshaogou Formation which consists of terrigenous fine conglomerate, sandstone, sandy mudstone and mudstone, depositing in alluvial to lacustrine and fan delta sedimentary environments. Detailed paleomagnetic measurements of this sequence at Yumen clearly reveal eleven pairs of normal and reversed polarities. Fossil mammals found around the section support that most of the observed polarities can be well correlated with chrons between 13n and 18r of the standard geomagnetic polarity time scale, yielding ages of 40.2-33.35 Ma. The mean declinations of this sequence and its immediately above stratigraphy indicate an 18.3° rapid clockwise rotation of the Hexi Corridor. Since this sequence has been strongly folded and is capped by an angular unconformity, we think that the presence of the thick alluvial fan conglomeration at the bottom of the foreland basin may indicate the initial deformation and uplift of the northern Qilian Shan. This process could occur at latest at 40.2 Ma, driven by the faults NQF and KLF that thrust onto the Hexi corridor respectively from its southern and northern margins. These faults are in an early response to the collision of India with Asia, while the unconformable termination and rotation of the Huoshaogou Formation at ~33.35 Ma indicate other early episode of rapid tectonic deformation and uplift of the northern Tibet. | DAI Shuang FANG Xiaomin SONG Chunhui GAO Junping GAO Donglin LI Jijun | 2005 | Chinese Science Bulletin2005,50,15: | 30 |
| 2 | Clinical impact and mechanisms of hepatitis B virus infection concurrent with non-alcoholic fatty liver disease显示文摘Chronic hepatitis B(CHB)virus infection is an important threat to global health despite the administration of vaccines and the use of antiviral treatments.In recent years,as the prevalence of obesity and metabolic syndrome has increased,non-alcoholic fatty liver disease(NAFLD)in patients with CHB has become more common.Both diseases can lead to liver fibrosis and even hepatocellular carcinoma,but the risk of dual etiology,outcome,and CHB combined with NAFLD is not fully elucidated.In this review,we assess the overlapping prevalence of NAFLD and CHB,summarize recent studies of clinical and basic research related to potential interactions,and evaluate the progressive changes of treatments for CHB patients with NAFLD.This review increases the understanding of the relationship and mechanisms of interaction between steatosis and hepatitis B virus infection,and it provides new strategies for the future clinical management and treatment of CHB combined with NAFLD. | Xin Tong Yu Song Shengxia Yin Jian Wang Rui Huang Chao Wu Junping Shi Jie Li | 2022 | Chinese Medical Journal2022,,14: | 4 |
| 3 | Thermal conductivity of natural rubber nanocomposites with hybrid fillers显示文摘Natural rubber nanocomposites filled with hybrid fillers of multi-walled carbon nanotubes(CNTs) and carbon black(CB) were prepared. CNTs were ultrasonically modified in mixture of hydrogen peroxide(H2O2) and distilled water(H2O). The functional groups on the surface of CNTs, changes in nanotube structure and morphology were characterized by Fourier transform infrared spectroscopy(FT-IR), Raman Spectroscopy, and transmission electron microscopy(TEM). It shows that hydroxyl(OH·) is successfully introduced. The surface defects of modified CNTs were obviously higher than those of original CNTs, and the degree of agglomeration was greatly reduced. Thermal conductivity of the composites was tested by protection heat flow meter method. Compared with unmodified CNTs/CB filling system, the thermal conductivity of hybrid composites is improved by an average of 5.8% with 1.5 phr(phr is parts per hundred rubber) of hydroxyl CNTs and 40 phr of CB filled. A three-dimensional heat conduction network composed of hydroxyl CNTs and CB, as observed by TEM, contributes to the good properties. Thermal conductivity of the hybrid composites increases as temperature rises. The mechanical properties of hybrid composites are also good with hydroxyl CNTs filled nanocomposites;the tensile strength, 100% and 300% tensile stress are improved by 10.1%, 22.4% and 26.2% respectively. | Junping Song Xiteng Li Kaiyan Tian Lianxiang Ma Wei Li Shichune Yao | 2019 | Chinese Journal of Chemical Engineering2019,27,4: | 3 |
| 4 | Randomized,multicenter,open-label trial of autologous cytokine-induced killer cell immunotherapy plus chemotherapy for squamous non-small-cell lung cancer:NCT01631357显示文摘Dear Editor,Cytokine-induced killer(CIK)cells have been recognized as a new type of anti-tumor effector cells.CIK cells are a mixture of T lymphocytes.Among them,CD3+/CD56+T cells,which are rare in uncultured peripheral blood,are the main effector cells.CIK cells can proliferate rapidly in vitro,with stronger antitumor activity,broader target tumor spectrum,and lower adverse effect than other reported antitumor effector cells.1 Their ease of production in vitro and antitumor potential have made them suitable candidates for cell therapy regimens in solid and hematopoietic tumor treatments.1,2 Our previous retrospective study showed that the median progression-free survival(PFS)and overall survival(OS)in untreated,advanced non-small-cell lung cancer(NSCLC)patients who received CIK cell immunotherapy plus chemotherapy(13 and 24 months,respectively)were significantly longer than in those who received chemotherapy alone(6 and 10 months,respectively).2 But so far,there is no prospective,multicenter clinical study in lung cancer.Based on our previous study,we designed this randomized,multicenter,open-label trial to further evaluate the clinical efficacy of CIK cell immunotherapy plus chemotherapy in patients with advanced squamous NSCLC(ClinicalTrials.gov number,NCT01631357). | Liang Liu Quanli Gao Jingting Jiang Junping Zhang Xin Song Jiuwei Cui Yunbin Ye Zhiyu Wang Xinwei Zhang Xiubao Ren | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 2 |
| 5 | Study on the resistance spot welding technology of 22MnMoB hot stamping quenched steel显示文摘In this paper,the spot welding technology of a new kind of 22 MnMoB hot stamping quenched steel sheet was systematically studied by power frequency spot welder.Through a series of technology and test experiments,we have obtained the optimal spot welding technological parameter condition.According to the results,the relations among spot welding technological parameter,welding nugget,mechanical property and fracture mode were discussed.The effects of all the welding parameters such as welding current,welding time and electrode force on the quality of joint can be boiled down to one thing—the diameter of welding nugget.The experimental results showed that welding nugget diameter determines the mechanical property of spot welding joint and the relation between welding nugget diameter and the mechanical property of joint presents a kind of linear mathematic representation.There are two typical fracture models of 22 MnMoB hot stamping quenched steel sheet,i.e.,interfacial fracture and nugget pullout.Other than mild steel or normal high strength steel,in the shearing tensile test,hot stamping quenched steel has a great tendency to fail in interfacial mode due to the effects of high strength matrix structure,welding soft zone and the porosity level of fusion zone. | Feng Yi Ma Mingtu Hua Fu'an Zhang Junping Song Leifeng Jin Qingsheng | 2014 | Engineering Sciences2014,12,5: | 2 |
| 6 | Structural transformation of carbon - encapsulated iron nanoparticles during heat - treatment at 1 000 ℃ 显示文摘 | JUNPING HUO HUAIHE SONG XIAOHONG CHEN | 2007 | Materials Chemistry and Physics2007,101,: | 1 |
| 7 | Isolation and expression of McF3H gene in the leaves of crabapple显示文摘 | Hongxiang Shen Jie Zhang Yuncong Yao Ji Tian Tingting Song Jian Geng Junping Gao | 2012 | Acta Physiologiae Plantarum2012,,4: | 1 |
| 8 | Preparation of carbon-encapsulated iron nanoparticles by co-carbonization of aromatic heavy oil and ferrocene显示文摘 | Junping Huo Huaihe Song Xiaohong Chen | 2004 | Carbon2004,42,: | 1 |
| 9 | Glial Cell-Derived Neurotrophic Factor Attenuates Neuropathic Pain in a Mouse Model of Chronic Constriction Injury: Possible Involvement of E-cadherin/p120ctn Signaling显示文摘 | Cunjin Wang Hongjun Wang Jun Pang Li Li Suming Zhang Ge Song Na Li Junping Cao Licai Zhang | 2014 | Journal of Molecular Neuroscience2014,,2: | 1 |
| 10 | Recycle-Friendly Aluminum Alloy Sheets for Automotive Applications Based on Hemming显示文摘Unavoidably,Fe impurities are mixed into Al alloys during recycling of aluminum automotive parts.High Fe content recyclefriendly aluminum alloy sheets(RASs)are discussed in terms of their applications to car body parts and closures.RASs have advantages,such as they are low cost and light weight,they require less energy to process,and they reduce emissions when used in vehicles.The hemming ability of RASs was investigated through various quenching rates and hot-rolling reduction rates.The hemming factor(HF)values of low Fe content samples(0.1 and 0.3 wt%Fe content)were 2 and 3.The hemming ability of samples with an Fe content of 0.5 wt%was unacceptable for applications to automotive outer closures(i.e.,HF values of 4 and 5).The HF values changed from 3 to 5 for even higher Fe content samples(0.8 wt%Fe),depending on the quenching and hot-rolling reduction rates.Lower quenching(air quenching)and lower hot-rolling reduction rates(6-pass hot rolling)both improved the hemming ability of the high Fe content samples.A low-cost and recycle-friendly aluminum alloy automotive sheet from end-of-life vehicles is presented,and its hemming properties are characterized. | Hongzhou Lu Junping Zhang Ni Tian Xinli Song Mingtu Ma Guimin Lu | 2018 | Automotive Innovation2018,1,1: | 1 |
| 11 | Modified graphite filled natural rubber composites with good thermal conductivity显示文摘The rubber composites with good thermal conductivity contribute to heat dissipation of tires. Graphite filled natural rubber composites were developed in this study to provide good thermal conductivity. Graphite was coated with polyacrylate polymerized by monomers including methyl methacrylate, n-butyl acrylate and acrylic acid. The ratios between a filler and acrylate polymerization emulsion and those between monomers were varied. Eight types of surface modification formulas were experimentally investigated. Modification formula can affect coating results and composite properties greatly. The best coating type was achieved by a ratio of1:1 between methyl methacrylate and n-butyl acrylate. The coating of graphite was thermally stable in a running tire. Filled with modified graphite, the tire thermal conductivity reached up to 0.517–0.569 W·m-1·K-1. In addition, the mechanical performance was improved with increased crosslink density, extended scorch time and short vulcanization time. | Junping Song Lianxiang Ma Yan He Haiquan Yan Zan Wu Wei Li | 2015 | Chinese Journal of Chemical Engineering2015,23,5: | 1 |
| 12 | Remote sensing image registration based on retrofitted SURF algorithm and trajecto ries generated from Lissajous figures显示文摘 | SONG Zhili ZHANG Junping | 2010 | Geoscience and Remote Sensing Letters2010,7,3: | 1 |
| 13 | Digital Integrated Model of Government Resources under E-government Environ- ment显示文摘 | Junping Qiu Yanhui Song | 2010 | The International Conference on Internet Technology and Applications2010,,8: | 1 |
| 14 | Research on load balance of Service Capability Interaction Management显示文摘 | Jiexi Zha JunPing Wang Renmin Han Maoqiang Song | 2010 | 3rd IEEE International Conference on Communication Networking & Broadcasting2010,12,1: | 1 |
| 15 | Remote sensing image registration based on retrofitted SURF algorithm and trajectories generated from Lissajous figures显示文摘 | Zhili Song Junping Zhang | 2010 | IEEE Geoscience and Remote Sensing Letters2010,7,3: | 1 |
| 16 | Aged hematopoietic stem cells entrap regulatory T cells to create a prosurvival microenvironment显示文摘Although DNA mutation drives stem cell aging,how mutation-accumulated stem cells obtain clonal advantage during aging remains poorly understood.Here,using a mouse model of irradiation-induced premature aging and middle-aged mice,we show that DNA mutation accumulation in hematopoietic stem cells(HSCs)during aging upregulates their surface expression of major histocompatibility complex class II(MHCII).MHCII upregulation increases the chance for recognition by bone marrow(BM)-resident regulatory T cells(Tregs),resulting in their clonal expansion and accumulation in the HSC niche.On the basis of the establishment of connexin 43(Cx43)-mediated gap junctions,BM Tregs transfer cyclic adenosine monophosphate(cAMP)to aged HSCs to diminish apoptotic priming and promote their survival via activation of protein kinase A(PKA)signaling.Importantly,targeting the HSC–Treg interaction or depleting Tregs effectively prevents the premature/physiological aging of HSCs.These findings show that aged HSCs use an active self-protective mechanism by entrapping local Tregs to construct a prosurvival niche and obtain a clonal advantage. | Weinian Liao Chaonan Liu Ke Yang Jun Chen Yiding Wu Shuzhen Zhang Kuan Yu Lisha Wang Li Ran Mo Chen Fang Chen Yang Xu Song Wang Fengchao Wang Qian Zhang Jinghong Zhao Lilin Ye Changhong Du Junping Wang | 2023 | Cellular & Molecular Immunology2023,20,10: | 0 |
| 17 | Design of a search and rescue terminal based on the dual-mode satellite and CDMA network显示文摘The current goal is to create a set of portable terminals with GPS/BD2 dual-mode satellite positioning, vital signs monitoring and wireless transmission functions. The terminal depends on an ARM processor to collect and combine data related to vital signs and GPS/BD2 location information, and sends the message to headquarters through the military CDMA network. It integrates multiple functions as a whole. The satellite positioning and wireless transmission capabilities are integrated into the motherboard, and the vital signs sensors used in the form of belts communicate with the board through Bluetooth. It can be adjusted according to the headquarters' instructions. This kind of device is of great practical significance for operations during disaster relief, search and rescue of the wounded in wartime, non-war military operations and other special circumstances. | ZHAO JunPing 1* , ZHANG Xuan 2 , ZHENG Bing 1 , ZHOU YuBin 3 , SONG Hao 2 , SONG Wei 2 , ZHANG MeiKui 1 , LIU TongZe 1 & ZHOU Li 1 1 Institute of Medical Informatics, General Hospital of PLA, Beijing 100853, China 2 Beijing Aerospace Science & Industry Century Satellite Hi-Tech Co. Ltd., Beijing 100070, China 3 Institute of Aviation Medicine, Beijing 100842, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010,53,12: | 0 |
| 18 | Global Existence,Uniqueness and Pathwise Property of Solutions to a Stochastic Rssler-Lorentz System显示文摘The authors integrate two well-known systems, the Rssler and Lorentz systems,to introduce a new chaotic system, called the Lorentz-Rssler system. Then, taking into account the effect of environmental noise, the authors incorporate white noise in both Rssler and Lorentz systems to have a corresponding stochastic system. By deriving the uniform a priori estimates for an approximate system and then taking them to the limit,the authors prove the global existence, uniqueness and the pathwise property of solutions to the Lorentz-Rssler system. Moreover, the authors carried out a number of numerical experiments, and the numerical results demonstrate their theoretic analysis and show some new qualitative properties of solutions which reveal that the Lorentz-Ro¨ssler system could be used to design more complex and more secure nonlinear hop-frequence time series. | Song JIANG Junping YIN | 2015 | Chinese Annals of Mathematics,Series B2015,36,1: | 0 |
| 19 | Longitudinal proteomic investigation of cOVID-19 vaccination显示文摘Although the development of covID-19 vaccines has been a remarkable success,the heterogeneous individual antibody generation and decline over time are unknown and still hard to predict.In this study,blood samples were collected from 163 participants who next received two doses of an inactivated COvVID-19 vaccine(CoronaVac)at a 28-day interval.Using TMT-based proteomics,we identified 1,715 serum and 7,342 peripheral blood mononuclear cells(PBMCs)proteins.We proposed two sets of potential biomarkers(seven from serum,five from PBMCs)at baseline using machine learning,and predicted the individual seropositivity 57 days after vaccination(AUC=0.87).Based on the four PBMC's potential biomarkers,we predicted the antibody persistence until 180 days after vaccination(AUC=0.79).Our data highlighted characteristic hematological host responses,including altered lymphocyte migration regulation,neutrophil degranulation,and humoral immune response.This study proposed potential blood-derived protein biomarkers before vaccination for predicting heterogeneous antibody generation and decline after coVID-19 vaccination,shedding light on immunization mechanisms and individual booster shot planning. | Yingrui Wang Qianru Zhus Rui Sun Xiao Yi Lingling Huang Yifan Hu Weigang Ge Huanhuan Gao xinfu Ye Yu Song Li Shao Yantao Li Jie Li Tiannan Guo Junping Shi | 2023 | Protein & Cell2023,14,9: | 0 |
| 20 | Nanoscale superconductivity of ?-Ga islands grown by molecular beam epitaxy显示文摘We report on the preparation and superconductivity of metastable γ-Ga islands on Si(111) substrate. The Ga grows in a typical Volmer-Weber mode at a low temperature of 110 K, resulting in formation of Ga nanoislands at various sizes with the identical γ-phase. In-situ low temperature scanning tunneling spectra reveal quantized electronic states in ultrathin Ga islands. It is found that both the lateral size and thickness of the Ga islands strongly suppress the superconductivity. Due to substantial surface energy contribution, the transition temperature Tc scales inversely with the island thickness and the minimum thickness for the occurrence of superconductivity is calculated to be two monolayers. | ZHANG HuiMin PENG JunPing GUAN JiaQi LI Zhi SONG CanLi WANG LiLi HE Ke MA XuCun XUE QiKun | 2015 | Science China(Physics,Mechanics & Astronomy)2015,58,10: | 0 |