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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Jackson and Schuler (1985) Revisted:Meta-Analysis of the Relationships Between Role Ambiguity,Role Conflict,and Job performance显示文摘 | Travis C Tubre Judith M Collins | 2000 | Journal of Management2000，26，1： | 1 |
| 3 | Confirmation of Association Between Autism and the Mitochondrial Aspartate/Glutamate Carrier SLC25A12 Gene on Chromosome 2q31 显示文摘 | Ricardo S Judith C Eleanor M | 2005 | Am J Psychiatry2005，162，： | 1 |
| 4 | Structure and properties of pyruvate decarboxylase and site - directed mutagenesis of the Zymomonas mobilis enzyme显示文摘 | Judith M C Ronald G D | 1998 | Biochimica Biophysica Acta1998，1385，： | 1 |
| 5 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 6 | Focal points in pure coordination games:An experimental investigation显示文摘 | Judith M Starmer C Sugden R | 1994 | Theory and Decision1994，36，2： | 1 |
| 7 | Carboxymethylation of cashew tree exudate polysaecharide 显示文摘 | I)URCII ENE A S REGINA C M JUDITH P A | 2004 | Carbohydrate Polymers2004，58，2： | 1 |
| 8 | Grossman,intellectual property rights and north-south trade显示文摘 | Chin Judith C Gene M | 1990 | Cambrige1990，1990，： | 1 |
| 9 | Controlled -release oxyeodone relieves neuropathie pain :a randomized controlled trial in painful diabetic neuropathy显示文摘 | C Peter NW Dwight M Judith WW | 2003 | Pain2003，105，： | 1 |
| 10 | Towards an integrated global framework to assess the impacts of land use and management change on soil carbon: current capability and future vision显示文摘 | Pete Smith Christian A. Davies Stephen Ogle Giuliana Zanchi Jessica Bellarby Neil Bird Robert M. Boddey Niall P. M c Namara David Powlson Annette Cowie Meine Noordwijk Sarah C. Davis Daniel DE B. Richter Len Kryzanowski Mark T. Wijk Judith Stuart Akira Ki | 2012 | Glob Change Biol2012，，7： | 1 |
| 11 | Structure and properties of pyruvate decarboxylase and site directed mutagenesis of the Zymomonas mobilis enzyme显示文摘 | Judith M C Honald G D | 1998 | Biochimica Biophysica Acta1998，1385，： | 1 |
| 12 | Cornwell nitrogen, phosphorus and sulfur dynamics in a low salinity marsh system dominated by Spartina aherniflora 显示文摘 | JUDITH M S JEFFERY C | 2001 | Wetland2001，21，4： | 1 |
| 13 | Application of a PDGF-containing novel gel for cutaneous wound he',cling显示文摘 | Judith R Nilhya M Rose C el al | 2010 | Life Set2010，87，12： | 1 |
| 14 | Environmental fate of explosives显示文摘 | Judith C P James M B | 2002 | Thermoehimiea Aeta2002，384，： | 1 |
| 15 | Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme 显示文摘 | Judith M C Ronald G D | 1998 | Biochimica Biophysica Acta1998，1385，： | 1 |
| 16 | Receptor Model andEmissions Inventory Source Apportionments of NonmethaneOrganic Gases in California,San Joaquin Valley and SanFrancisco Bay Area显示文摘 | ERIC M F JOHN G W JUDITH C H | 1995 | Atmospheric Enuironment1995，29，21： | 1 |
| 17 | Structure and properties of pyruvate decarboxylase and site - directed mutagenesis of the Zymomonas mobilis enzyme显示文摘 | Judith M C Ronald G D | 1998 | Biochimica Biophysica Acta1998，1385，： | 1 |
| 18 | Cornwell nitrogen, phosphorus and sulfur dynamics in a low salinity marsh system dominated by Spartina alterniflora显示文摘 | Judith M S Jeffery C | 2001 | Wetland2001，21，4： | 1 |
| 19 | Ovarian and extraovarian endometriosis-associated cancer显示文摘 | Susan C Modesitt Guillermo Tortolero-Luna Jubilee B Robinson David M Gershenson Judith K Wolf | 2002 | Obstetrics & Gynecology2002，，： | 1 |
| 20 | Influence of temperature and pressure on the dynamic properties of rubber-modified asphalt concrete 显示文摘 | Judith C Wang ASCE S M Zeng Xiangwu ASCE M | 2006 | Journal of Materials in Civil Engineering ? ASCE2006，125，： | 1 |
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