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| 1 | PM_(2.5)及其测量与影响研究简史显示文摘美国率先建立的国家环境空气质量标准(NAAQS)旨在保护公众健康,而该理念已被包括中国在内的众多国家所采用。针对大气悬浮颗粒物(PM),NAAQS根据PM在仪器检测以及人体吸入时的粒径选择性特征,定义了总悬浮颗粒(TSP)、PM_(10)、PM_(2.5)及其相应的质量浓度标准。这些指标的建立是基于长达300年来颗粒物监测技术发展及其危害评价的结果。因此2012年中国在颁布实施新PM_(2.5)空气质量标准时,PM_(2.5)的监测及评价方面有了更多科学积累与技术选择。本文简要回顾了PM的粒径分布、化学组成、可吸入特征、人体健康效应及空气质量标准等研究简史,根据其他国家的发展经验,提出中国在观测网络设计、测量仪器选择和使用、质量控制和质量保证及监测结果分析等方面需要确立自己独特的行业指南。对于未来空气质量的管理和标准制定,应同时考虑多种污染物及其对公众健康、能见度、气候、材料及生态系统的影响。 | CHOW Judith C 曹军骥 李顺诚 王小亮 WATSON John G | 2012 | 地球环境学报2012，3，5： | 17 |
| 2 | 七个发达国家卫生系统的领导与治理显示文摘本文运用结构式调查方法,探讨了澳大利亚、英国、德国、荷兰、挪威、瑞典和瑞士七个发达国家卫生系统的领导和治理情况。领导与治理模式包含三项基本职能:优先顺序设置、绩效监管和问责制。各国卫生系统的领导和治理方法存在着显著差异,零散并略显随意。虽然各国在卫生系统的总体目标上达成了共识,但设置优先顺序的途径各不相同。成本效益分析作为设置卫生系统运行优先顺序的一个主要方法被各国加以广泛运用,但并未发挥核心作用。各国虽然处于不同的发展阶段,但绩效监管却能广泛吸收有益意见。问责制特别是在最优方法的不确定性方面,各国之间的差异最大。大多数情况下,市场机制、选举程序、直接经济激励以及专业监督与控制等几种不同问责机制的组合可能更为合适。而且这些机制应与优先顺序设置和绩效监管协调一致。 | Peter C Smith Anders Anell Reinhard Busse Luca Crivelli Judith Healy Anne Karin Lindahl Gert Westert Tobechukwu Kene | 2012 | 中国卫生政策研究2012，5，11： | 13 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | PM 2.5 chemical source profiles for vehicle exhaust, vegetative burning, geological material, and coal burning in Northwestern Colorado during 1995显示文摘 | John G Watson Judith C Chow James E Houck | 2001 | Chemosphere2001，，8： | 2 |
| 5 | 兵马俑博物馆冬季室内大气悬浮颗粒物与游客数量的关系显示文摘通过对秦始皇兵马俑博物馆铜车马展厅和一号坑室内采集的冬季大气悬浮颗粒物进行单颗粒分析,评价了在具有不同通风条件的两个展厅中,游客数量对大气悬浮颗粒物的影响。研究中采用配备能谱的扫描电子显微镜对单颗粒进行了形貌和元素组成分析,以判断室内悬浮颗粒的来源和化学组成差异,同时监测了两个展厅室内的微环境变化。结果显示,在铜车马展厅室内悬浮颗粒的昼夜质量浓度之比(1.30-3.12),明显高于同期的一号坑(0.96-2.59)和室外(0.68-1.79),表明在铜车马展厅游客数量对颗粒物质量浓度的贡献大于在一号坑内。室内、外对比的结果表明,悬浮颗粒物的质量浓度、粒径分布和颗粒类型等特性,在配备了机械通风设备的铜车马展厅中受游客数量的影响较大,而在自然通风为主的一号坑中,通风条件则成为决定因素。颗粒物组成分析显示,博物馆冬季的室内悬浮颗粒主要由黄土中的矿物颗粒、烟炱等低原子序数的颗粒、硫酸盐、燃煤飞灰和生物质颗粒组成。除烟炱和铝硅酸盐会造成对文物的脏污外,随着温、湿度的波动,硫酸钙的结晶、溶解、渗透和再结晶作用都会产生应力,导致兵马俑表面的风化。 | 胡塔峰 曹军骥 李旭祥 Lee Shun-Cheng Judith C Chow John G Watson 容波 | 2009 | 中国粉体技术2009，15，2： | 2 |
| 6 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012，，10： | 2 |
| 7 | 初级保健中恶性肿瘤早期诊断的预警症状:运用全科医疗机构研究数据库进行的队列研究显示文摘目的根据初级保健中的研究,评价在大规模人群中预警症状与随后的恶性肿瘤诊断之间的关系。设计队列研究。地点英国全科医疗机构研究数据库。患者 1994至2000年间在英国128家全科医疗机构注册的762325名年龄在15岁及以上的患者。既往无恶性肿瘤病史,首次出现血尿、咯血、吞咽困难或直肠出血症状。结局评估指标首次出现的血尿、咯血、吞咽困难或直肠出血症状,自症状出现3年内,在泌尿道、呼吸道、食管、结肠以及直肠等部位恶性肿瘤诊断中的阳性预测值。同时评价其似然比和敏感性。结果在11108名首发血尿患者中,有472名男性和162名女性新近诊断泌尿道恶性肿瘤,总的3年阳性预测值男性为7.4%(95%可信区间为6.8%~8.1%),女性为3.4%(2.9%~4.0%)。在4812名首发咯血患者中,有220名男性(阳性预测值7.5%,6.6%~8.5%)和81名女性(4.3%,3.4%~5.3%)诊断呼吸道恶性肿瘤。5999名首次出现吞咽困难的患者中,食管恶性肿瘤诊断在男性有150人(阳性预测值5.7%,4.9%~6.7%),女性有81人(2.4%,1.9%~3.0%)。在15289名首发直肠出血症状的患者中,则有184名男性(阳性预测值2.4%,2.1%~2.8%)和154名女性(2.0%,1.7%~2.3%)诊断结直肠恶性肿瘤。预测值随着患者年龄的增加而增加,而且值非常高,例如,年龄在75~84岁的男性咯血患者(17.1%,13.5%~21.1%)和年龄在65~74岁的男性吞咽困难患者(9.0%,6.8%~11.7%)。结论首次出现预警症状时恶性肿瘤诊断可能性增加,尤其在男性及年龄大于65岁的患者人群中。这些数据显示,对于预警症状进行早期评价有助于在早期或易于处理的阶段发现或鉴别恶性肿瘤。 | Roger Jones Radoslav Latinovi Judith Charlton Martin C Gulliford 张国庆 | 2007 | 英国医学杂志中文版2007，10，5： | 2 |
| 8 | Jackson and Schuler (1985) Revisted:Meta-Analysis of the Relationships Between Role Ambiguity,Role Conflict,and Job performance显示文摘 | Travis C Tubre Judith M Collins | 2000 | Journal of Management2000，26，1： | 1 |
| 9 | Differences in the carbon composition of source profiles for diesel-and gasoline-powered vehicles 显示文摘 | WATSON J G JUDITH C C | 1994 | Atmospheric Environment1994，25，： | 1 |
| 10 | Confirmation of Association Between Autism and the Mitochondrial Aspartate/Glutamate Carrier SLC25A12 Gene on Chromosome 2q31 显示文摘 | Ricardo S Judith C Eleanor M | 2005 | Am J Psychiatry2005，162，： | 1 |
| 11 | An efficient algorithm for the calculation of a constant Q transform显示文摘 | JUDITH C B | 1992 | The Journal of the Acoustical Society of American1992，92，5： | 1 |
| 12 | High throughput protein fold identification by using experimental constrains derived from intramolecular cross-links and mass spectrometry显示文摘 | Young MM Tang N Judith C | 2000 | PNAS2000，97，11： | 1 |
| 13 | Chilling injury inmango fruit peel : Cultivar differences are related to the activityof phenylalanine ammonia lyase 显示文摘 | Sugunya C Saichol K Judith B | 2011 | Postharvest Biology andTechnology2011，62，： | 1 |
| 14 | Educating undergraduate medical students about oncology : a literature review 显示文摘 | Judith C Jane D Alison J | 2006 | J Clin Oncol2006，24，12： | 1 |
| 15 | An Empirical In- vestigation of Client Managers' Responsibilities in Managing Off- shore Outsoureing of Software -Testing Projects显示文摘 | Radhika P Jain Robin S Poston Judith C Simon | 2011 | IEEE Transac- tions on Engineering Management2011，58，4： | 1 |
| 16 | Structure and properties of pyruvate decarboxylase and site - directed mutagenesis of the Zymomonas mobilis enzyme显示文摘 | Judith M C Ronald G D | 1998 | Biochimica Biophysica Acta1998，1385，： | 1 |
| 17 | A laboratory resuspension chamber to measure fugitive dust size distributions and chemical compositions显示文摘 | JUDITH C C JOHN G W JAMES E H | 1994 | Atmospheric Environment1994，28，21： | 1 |
| 18 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 19 | Chlorophyll a fluorescence and car- bon assimilation in developing leaves of light-grown cu- cumber显示文摘 | Judith G C Kenji () | 1990 | Plant Physiol1990，93，： | 1 |
| 20 | Update in women's health显示文摘 | Judith ME Nancy C Dolan PC | 2000 | Ann Intern Med2000，133，6： | 1 |
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