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| 1 | Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated. | Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz | 2007 | World Journal of Gastroenterology2007，13，9： | 23 |
| 2 | Virtual development of ride and handling characteristics for advanced passenger cars显示文摘 | Jochen R | 2003 | Vehicle System Dynamics2003，40，13： | 1 |
| 3 | A conditionally immortalized human podocyte cell line demonstrating nephrin and podocinexpression显示文摘 | Moin A S Michael J O’Hare Jochen R | 2002 | J Am Soc Nephrol2002，13，： | 1 |
| 4 | Supramolecular architecture of cyanobacterial thylakoid membranes: How is the phycobilisome connected with the photosystems?显示文摘 | Dirk Bald Jochen Kruip Matthias R?gner | 1996 | Photosynthesis Research1996，，2： | 1 |
| 5 | The alpha/beta- hydrolase fold 3DM database (ABHDB) as a tool for protein engineering显示文摘 | Kourist R Jochens H Bartsch S | 2010 | Chembiochem2010，11，12： | 1 |
| 6 | Continuous Cleaning of Heat Exchanger with Recirculating Fluidized Bed显示文摘 | JOCHEN St Kollbach W Dahm R Rautenbach | 1987 | HEAT TRANSFER ENGINEERING1987，8，4： | 1 |
| 7 | High performance system dynamics simulation of the entire system tire-suspension-steering-vehicle显示文摘 | DIETER A MICHAEL G JOCHEN R | 2009 | Vehicle System Dynamics2009，27，56： | 1 |
| 8 | Evidence for the existence of trimeric and monomeric Photosystem I complexes in thylakoid membranes from cyanobacteria显示文摘 | Jochen Kruip Dirk Bald Egbert Boekema Matthias R?gner | 1994 | Photosynthesis Research1994，，3： | 1 |
| 9 | Interferences with two-site immunoassays by human anti-mouse antibodies formed by patients treated with monoclonal antibodies:comparison of different bolcking reagents显示文摘 | Jochen R | 1998 | Clin Chem1998，44，： | 1 |
| 10 | What Makes Good Antioxidants in Lipid-Based Systems? The Next Theories Beyond the Polar Paradox显示文摘 | Micka?l Laguerre Christelle Bayrasy Atikorn Panya Jochen Weiss D. Julian McClements Jér?me Lecomte Eric A. Decker Pierre Villeneuve | 2015 | Critical Reviews in Food Science and Nutrition2015，，2： | 1 |
| 11 | New anti-angiogenic strategies in pediatric solid malignancies: agents and biomarkers of a near future显示文摘 | Melissa Taylor Jochen R?ssler Birgit Geoerger Gilles Vassal Fran?oise Farace | 2010 | Expert Opinion on Investigational Drugs2010，，7： | 1 |
| 12 | Endoscopic sentinel lymphadenectomy as a new diagnostic approach in the NO neck显示文摘 | Jochen A Werner N R Saupndzhiev A | 2004 | Eur Arch Otorhinolaryngol2004，261，15： | 1 |
| 13 | Monitoring PAHs in the Brisbane River and Moreton Bay, Australia, using semipermeable membrane devices and EROD activity in yellowfin bream, Acanthopagrus australis显示文摘 | Shaw M Tibbetts I R Jochen M F | 2004 | Chemosphere2004，56，： | 1 |
| 14 | Toward the development of podocyte specific drugs显示文摘 | Jochen R Vineet G Andreas D | 2010 | Kidney Int2010，77，： | 1 |
| 15 | The plant transcription factor TGA1 stimulates expression of the CaMV 35S promoter in Saccharomyces cerevisiae显示文摘 | Jochen Rüth Rudolf J. Schweyen Heribert Hirt | 1994 | Plant Molecular Biology1994，，2： | 1 |
| 16 | Uncalibrated pulse power analysis fails to reliably measure cardiac output in patients undergoing coronary artery bypass surgery显示文摘 | Ole BL Jochen R Jan HL | 2011 | Critical Care2011，15，11： | 1 |
| 17 | Lean blowout limit and NOx production of a premixed sub-ppm NOx burner with periodic recirculation of combustion products显示文摘 | R K Jochen S Thomas | 2006 | Journal of Engineering for Gas Turbines and Power(Transactions of the ASME)2006，128，2： | 1 |
| 18 | Neuropsychological characterization of hepatic encephalopathy显示文摘 | Karin Weissenborn Jochen C Ennen Hans Schomerus Norbert Rückert Hartmut Hecker | 2001 | Journal of Hepatology2001，，5： | 1 |
| 19 | Development of fluid eonduits in the auriferous shear zone of the Hutti Gold Mine,India: evidence for spatially and temporally heterogeneous fluid flow显示文摘 | JOCHEN K AMANDA R MICHAEL M F | 2004 | Tectonophysics2004，378，12： | 1 |
| 20 | Cementitious properties of metallurgical alags显示文摘 | COALE R WOLHUTER C W JOCHENS P R | 1973 | Cement and Concrete Research1973，，3： | 1 |
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