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| 1 | Endoscopic and histologic characteristics of serrated lesions显示文摘In recent years , a second pathway for colonic carcinogenesis , distinct from the adenomatous pathway, has been explored. This is referred to as serrated pathway and includes three types of polyp,characterised by a serrated appearance of the crypts:hyperplastic polyps(HP),sessile serrated adenomas(SSA)or lesions,and traditional serrated adenomas.Each lesion has its own genetic,as well as macroscopic and microscopic morphological features.Because of their flat aspect,their detection is easier with chromoendoscopy(carmin indigo or narrow-band imaging).However,as we show in this review,the distinction between SSA and HP is quite difficult.It is now recommended to resect in one piece as it is possible the serrated polyps with a control in a delay depending on the presence or not of dysplasia.These different types of lesion are described in detail in the present review in general population,in polyposis and in inflammatory bowel diseases patients.This review highlights the need to improve characterization and understanding of this way of colorectal cancerogenesis. | Driffa Moussata Gilles Boschetti Marion Chauvenet Karine Stroeymeyt Stéphane Nancey Franoise Berger Thierry Lecomte Bernard Flourié | 2015 | World Journal of Gastroenterology2015，21，10： | 14 |
| 2 | 粉末型硅烷/有机硅添加剂在水泥基材中的应用显示文摘介绍了有机硅作为憎水剂在水泥基材料中的作用,介绍了有机硅粉状憎水剂的主要组分及其性能。通过实验证明,有机硅粉状添加剂SHP50及SHP60是一种高效的憎水剂,应用于水泥基干混材料中,赋予了砂浆良好的疏水特性。 | Jean-Paul LECOMTE Marc Thibaut | 2009 | 化学建材2009，，4： | 5 |
| 3 | 消泡剂对超滤膜的影响显示文摘膜污垢已成为作为分离和净化系统的超滤膜的主要缺陷。有关膜污垢的原因和理论,以及系统优化、污垢对膜寿命的影响。等研究已广泛开展。特别是人们发现,消泡剂可导致显著的膜污垢。本论文旨在讨论消泡剂膜污垢问题,研究膜污垢产生的主要原因,并介绍了用于超滤顺流工艺的无污垢消泡剂的开发。 | Jean-Paul Lecomte | 2007 | 食品与发酵工业2007，33，5： | 5 |
| 4 | Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring显示文摘现在有充分证据,对在使肥沃的后代显型的父亲的贡献多于公平 DNA。然而,这 nongenetic 继承的身份和机制糟糕被理解。在这个研究区域的更重要的问题之一是:在精子 DNA methylation 的变化为后代有 phenotypic 后果吗?我们以前报导了肥胖的雄的老鼠的后代与控制相比改变了葡萄糖新陈代谢并且这效果通过 nongenetic 工具被继承。这里,我们用一样的协议在一个新队描述调查进精子 DNA methylation。在高脂肪的节食的雄的老鼠是 30% 比喂控制的男性重在交配的时候(16-19 星期旧, n = 14/14 ) 。一小(0.25%) 在全部的 5-methyl-2 ’ 增加; -deoxycytidine 被液体层析双人脚踏车团 spectrometry 在肥胖的老鼠精子检测。那 retrotransposon DNA methylation 在精子说的有定序的充实蛋白质的染色体(MBD-Seq ) 和 pyrosequencing 揭示了的 methyl-CpG 绑定领域的染色体的重复部分的检查没被肥胖,而是 methylation 在整个染色体在卫星重复影响被增加。然而,从男 27-week-old 后代从的肌肉,肝,和精子的检查肥胖并且控制父亲(从 8 生的 n = 的两个组) 表明正常 DNA methylation 层次在后代开发期间被恢复。而且,没有变化在肥胖的老鼠精子在三个 genomic 印记被发现。我们的调查结果为 transgenerational epigenetic reprogramming 有含意。他们建议 postfertilization 机制为使导致 environmentally 的 DNA methylation 在精子房间改变的一些正常化存在。 | Neil A Youngson Virginie Lecomte Christopher A Maloney Preston Leung Jia Liu Luke B Hesson Fabio Luciani Lutz Krause Margaret J Morris | 2016 | Asian Journal of Andrology2016，18，6： | 3 |
| 5 | 美国国家级干旱监测业务产品介绍显示文摘 | Mark Svoboda Doug LeComte Mike Hayes Richard Heim Karin Gleason Jim Angel Brad Rippey Rich Tinker Mike Palecki David Stooksbury David Miskus Scott Stephens 王涓力(译) | 2006 | 干旱气象2006，24，1： | 3 |
| 6 | The application of remotesensing data to monitoring and modeling of soil erosion 显示文摘 | King C Baghdadi N Lecomte V | 2005 | CATENA2005，，62： | 1 |
| 7 | Finite difference compution of traveltime in very contrasted velocity models: a massively parallel approach and its associated tools显示文摘 | Podvin P Lecomte I | 1991 | Geophys J Int1991，105，1： | 1 |
| 8 | Experimental and kinetic modeling study of the reduction of NO by hydrocarbons and interactions with SO2 in a JSR at 1 atm显示文摘 | Philippe Dagaut Franck Lecomte | 2003 | Fuel2003，82，9： | 1 |
| 9 | Effect of solidification parameters on the growth geometry of MC carbide in IN- 100 dendritic monocrystals显示文摘 | R. Fernandez J. C. LeComte T. Z. Kattamis | 1978 | Metallurgical Transactions A1978，，10： | 1 |
| 10 | Glutathione S-transi'erase P1 polymorphism (Ile105Val) predicts cumulative neuropathy in patients receiving oxalipla- tin-based chemotherapy 显示文摘 | Lecomte T Landi B Beaune P | 2006 | Clin Cancer Res2006，12，10： | 1 |
| 11 | Impaired fasting glycemia and undiagnosed diabetes prevalence cardiovasular and behavioural risk factor显示文摘 | Lecomte P Vol S Caces E | 2002 | Diabetes Metab2002，28，4： | 1 |
| 12 | Dynamic tight glycemic control during and after cardiac surgery is effective, feasible, and safe显示文摘 | Patrick Lecomte Luc Foubert Frank Nobels | 2008 | Anesth Analg2008，107，1： | 1 |
| 13 | Non- dissociative electron capture by disulfide bonds 显示文摘 | Caries S Lecomte F Schermann J P | 2001 | J Phys Chem A2001，105，23： | 1 |
| 14 | Sudden death and physical activity and sports显示文摘 | P FORNES D LECOMTE | 2001 | Rev Prat2001，51，12： | 1 |
| 15 | RPE,a plant gene involved in early developmental steps of nematode feeding cells显示文摘 | Favery B Lecomte P Gil N | 1998 | The EmboJournal1998，17，： | 1 |
| 16 | Genetic improvement of agronomic traits of winter wheat cultivars released in France from 1946 to 1992显示文摘 | BRANCOURTH M DOUSSINAULT L G LECOMTE C | 2003 | Crop Science2003，43，： | 1 |
| 17 | Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients显示文摘 | Ouattara A Lecomte P Le Manach Y | 2005 | Anesthesiology2005，103，4： | 1 |
| 18 | An analytical model for the prediction of load distribution in multi-bolt composite joints including hole-location errors 显示文摘 | LECOMTE J BOIS C WARGNIER H | 2014 | Composite Structures2014，117，： | 1 |
| 19 | Novel functionalization routes of poly(ε-caprolactone) 显示文摘 | Philippe Lecomte Christophe Detrembleur Xudong Lou | 2000 | Macromol Symp2000，157，： | 1 |
| 20 | A de novo redesign of the WW domain 显示文摘 | Kraemer-Pecore CM Lecomte iT Desjarlais JR | 2003 | Protein Sci2003，12，10： | 1 |
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