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| 1 | Distribution of high-risk human papillomavirus genotype prevalence and attribution to cervical precancerous lesions in rural North China显示文摘Objective: Precise prevention is more desired for cervical cancer due to the huge population, high prevalence of human papillomavirus(HPV) infection in China and the vision of screen-and-treat strategies in low-and middleincome countries(LMICs). Considerations of combining type-specific prevalence and attribution proportion to high-grade cervical intraepithelial neoplasia are informative to more precise and effective region-specific cervical cancer prevention and control programs. The aim of the current study was to determine the genotype distribution of HPV and attribution to cervical precancerous lesions among women from rural areas in North China.Methods: A total of 9,526 women participated in the cervical cancer screening project in rural China. The samples of women who tested positive for HPV were retested with a polymerase chain reaction(PCR)-based HPV genotyping test. The attribution proportion of specific high-risk human papillomavirus(HR-HPV) types for different grades of cervical lesions was calculated by using the type contribution weighting method.Results: A total of 22.2%(2,112/9,526) of women were HR-HPV positive and HPV52(21.7%) was the most common HR-HPV genotype, followed by HPV58(18.2%), HPV53(18.2%) and HPV16(16.2%). The top three genotypes detected in HR-HPV-positive cervical intraepithelial neoplasia(CIN)1 were HPV16(36.7%), HPV58(20.4%), HPV56(15.3%). Among CIN2+, the most frequent genotypes were HPV16(75.6%), HPV52(17.8%),HPV58(16.7%). HPV16, 56, 58, 53, 52, 59, 68, and 18 combined were attributed to 84.17% of all CIN1 lesions,and HPV16, 58, and 52 combined were attributed to 86.98% of all CIN2+ lesions.Conclusions: The prevalence of HR-HPV infection among women from rural areas in North China was high and HPV16, HPV58, HPV52 had paramount attributable fraction in CIN2+. Type-specific HPV prevalence and attribution proportion to cervical precancerous lesions should be taken into consideration in the development of vaccines and strategy for screening in this population. | Shuang Zhao Xuelian Zhao Shangying Hu Jessica Lu Xianzhi Duan Xun Zhang Feng Chen Fanghui Zhao | 2019 | Chinese Journal of Cancer Research2019，31，4： | 30 |
| 2 | A novel Cu-bearing high-entropy alloy with significant antibacterial behavior against corrosive marine biofilms显示文摘The design of novel high-entropy alloys(HEAs)provides a unique opportunity for the development of structure-function integrated materials with high mechanical and antimicrobial properties.In this study,by employing the antibacterial effect of copper,a novel Al0.4CoCrCuFeNi HEA with broad-spectrum antibacterial and strong mechanical properties was designed.High concentrations of copper ions released from the HEA prevented growth and biofilm formation by biocorrosive marine bacterial species.These findings serve as a proof-of-concept for further development of unique HEA materials with high antimicrobial efficiency and mechanical properties,compared to conventional antibacterial alloys. | Enze Zhou Dongxu Qiao Yi Yang Dake Xu Yiping Lu Jianjun Wang Jessica A.Smith Huabing Li Hongliang Zhao Peter K.Liaw Fuhui Wang | 2020 | Journal of Materials Science & Technology2020，42，11： | 6 |
| 3 | Mobility in China,2020:a tale of four phases显示文摘2020 was an unprecedented year;with rapid and drastic changes in human mobility due to the COVID-19 pandemic.To understand the variation in commuting patterns among the Chinese population across stable and unstable periods,we used nationwide mobility data from 318 million mobile phone users in China to examine the extreme fluctuations of population movements in 2020,ranging from the Lunar New Year travel season(chunyun),to the exceptional calm of COVID-19 lockdown,and then to the recovery period.We observed that cross-city movements;which increased substantially in chunyun and then dropped sharply during the lockdown,are primarily dependent on travel distance and the socio-economic development of cities.Following the Lunar New Year holiday,national mobility remained low until mid-February,and COVID-19 interventions delayed more than 72.89 million people returning to large cities.Mobility network analysis revealed clusters of highly connected cities,conforming to the social-economic division of urban agglomerations in China.While the mass migration back to large cities was delayed,smaller cities connected more densely to form new clusters.During the recovery period after travel restrictions were lifted,the netflows of over 55%city pairs reversed in direction compared to before the lockdown.These findings offer the most comprehensive picture of Chinese mobility at fine resolution across various scenarios in China and are of critical importance for decision making regarding future public-health-emergency response,transportation planning and regional economic development,among others. | Suoyi Tan Shengjie Lai Fan Fang Ziqiang Cao Bin Sai Bing Song Bitao Dai Shuhui Guo Chuchu Liu Mengsi Cai Tong Wang Mengning Wang Jiaxu Li Saran Chen Shuo Qin Jessica R.Floyd Zhidong Cao Jing Tan Xin Sun Tao Zhou Wei Zhang Andrew J.Tatem Petter Holme Xiaohong Chen Xin Lu | 2021 | National Science Review2021，8，11： | 3 |
| 4 | [12] ane N_3-based BODIPY as a selective and sensitive off–on sensor for the sequential recognition of Cu^(2+) ions and ADP显示文摘A new [12]ane N3-based BODIPY sensor 1 showed highly selective and sensitive recognition of Cu2+ions through fluorescence quenching effect in aqueous solution. The above copper complex solution can further be used as a turn-on fluorescent probe for detecting ADP with high selectivity, and also applied in imaging of living cells. | Ying Zhang Yong-Guang Gao You-Di Shi Lian-Qian Tan Jessica S.Yue Zhong-Lin Lu | 2015 | Chinese Chemical Letters2015，26，7： | 3 |
| 5 | Prediction models of long‐term Cirrhosis and hepatocellular carcinoma risk in chronic hepatitis B patients: Risk scores integrating host and virus profiles显示文摘 | Mei‐Hsuan Lee Hwai‐I. Yang Jessica Liu Richard Batrla‐Utermann Chin‐Lan Jen Uchenna H. Iloeje Sheng‐Nan Lu San‐Lin You Li‐Yu Wang Chien‐Jen Chen | 2013 | Hepatology2013，，2： | 3 |
| 6 | Effect of solution condition on hydroxyapatite formation in evaluating bioactivity of B2O3 containing 45S5 bioactive glasses显示文摘The effects of testing solutions and conditions on hydroxyapatite(HAp)formation as a means of in vitro bioactivity evaluation of B2O3 containing 45S5 bioactive glasses were systematically investigated.Four glass samples prepared by the traditional melt and quench process,where SiO2 in 45S5 was gradually replaced by B2O3(up to 30%),were studied.Two solutions:the simulated body fluid(SBF)and K2HPO4 solutions were used as the medium for evaluating in vitro bioactivity through the formation of HAp on glass surface as a function of time.It was found that addition of boron oxide delayed the HAp formation in both SBF and K2HPO4 solutions,while the reaction between glass and the K2HPO4 solution is much faster as compared to SBF.In addition to the composition and medium effects,we also studied whether the solution treatments(e.g.,adjusting to maintain a pH of 7.4,refreshing solution at certain time interval,and no disturbance during immersion)affect HAp formation.Fourier transform infrared spectrometer(FTIR)equipped with an attenuated total reflection(ATR)sampling technique and scanning electron microscopy(SEM)were conducted to identify HAp formation on glass powder surfaces and to observe HAp morphologies,respectively.The results show that refreshing solution every 24 h produced the fastest HAp formation for low boron-containing samples when SBF was used as testing solution,while no significant differences were observed when K2HPO4 solution was used.This study thus suggests the testing solutions and conditions play an important role on the in vitro bioactivity testing results and should be carefully considered when study materials with varying bioactivities. | Xiaonan Lu Jessica Kolzow Roberto R.Chen Jincheng Du | 2019 | Bioactive Materials2019，4，1： | 3 |
| 7 | A Predictive Scoring System for the Seroclearance of HBsAg in HBeAg-seronegative Chronic Hepatitis B Patients with Genotype B or C Infection显示文摘 | Jessica Liu Mei-Hsuan Lee Richard Batrla-Utermann Chin-Lan Jen Uchenna H. Iloeje Sheng-Nan Lu Li-Yu Wang San-Lin You Chuhsing K. Hsiao Hwai-I. Yang Chien-Jen Chen | 2012 | Journal of Hepatology2012，，： | 2 |
| 8 | Glycine max (L.) Merr., Vigna radiata L. and Medicago sativa L. sprouts: A natural source of bioactive compounds显示文摘 | Luís R. Silva Maria J. Pereira Jessica Azevedo Rui F. Gon?alves Patrícia Valent?o Paula Guedes de Pinho Paula B. Andrade | 2013 | Food Research International2013，，1： | 2 |
| 9 | Drug screening: zebrafish as a tool for studying epileptic-related chemical compounds显示文摘 | Sha-Sha Zhao (1) (2) Yi-Liao Wang (3) Ming-Zhu Sun (3) Lu Lu (1) (2) Ya-Nan Wang (1) Delaney Pfister (4) Jessica Lee (4) Xin Zhao (3) Xi-Zeng Feng (1) Lei Li (4) | 2015 | Protein & Cell2015，6，11： | 1 |
| 10 | AFLP (ATG-AFLP)analysis in cotton显示文摘 | Yingzhi Lu Jessica Curtiss Danielle Miranda ATG-anchored | 2008 | Plant Cell Report2008，27，： | 1 |
| 11 | Efficacy and safety of entecavir compared to lamivudine in nucleoside-na?ve patients with chronic hepatitis B: a randomized double-blind trial in China显示文摘 | Guangbi Yao Chengwei Chen Weilun Lu Hong Ren Deming Tan Yuming Wang Daozheng Xu Zhengrong Jiang Jessica Liu Dong Xu Laurie MacDonald | 2007 | Hepatology International2007，，3： | 1 |
| 12 | Isolation of aslowly adhering cell fraction containing stem cells from murine skel-etal muscle by the preplate technique显示文摘 | Urhan Gharaibeh Aiping Lu Jessica Tebbets | 2008 | Nature Protocol2008，3，9： | 1 |
| 13 | Modeling Indirect Statistics of Surface Roughness显示文摘 | Lu Sun Zhanming Zhang Jessica Ruth | 2001 | Journal of Transportation Engineering2001，127，2： | 1 |
| 14 | Metallurgy at the Crossroads: New Analyses of Copper-based Objects at Tianshanbeilu, Eastern Xinjiang, China显示文摘Tianshanbeilu is the largest Bronze Age site in eastern Xinjiang, China. Stretching across the entire second millennium BC, it performed a prominent role in connecting the Hexi corridor, Central China and the steppe. A further insight into the metallurgical tradition and the metal supply network is of vital importance to improve our understanding of its multi-connected nature. This paper offers a new set of chemical and isotopic data on the copper-based objects at Tianshanbeilu, including alloying elements, trace elements(impurities) and lead isotopes. Combining the concentrations of arsenic and antimony reveals that arsenic was introduced to copper partially due to the use of specific minerals tethrahedrite-tennantite. Lead isotopes demonstrate that multiple sources of copper were employed at Tianshanbeilu and a majority of them are characterized by common lead, which appears rather different from those of the Central Plains and the Hexi corridor, but highly consistent with local ores. Surprisingly, one object at Tianshanbeilu contains the well-known highly radiogenic lead. This object undoubtedly marks the westernmost boundary of the distribution of the highly radiogenic lead. We also anticipate that more lead isotopic analyses in NW China will further contribute to the study of the highly radiogenic lead in Central China. | LIU Cheng LIU Ruiliang ZHOU Pengcheng LU Chun YANG Zengxin A.Mark POLLARD Peter HOMMEL MA Jian CUI Jianfeng Peter BRAY TONG Jianyi Jessica RAWSON | 2020 | Acta Geologica Sinica(English Edition)2020，94，3： | 1 |
| 15 | Modeling Indirect Statistics of Surface Roughness显示文摘 | Lu Sun Zhanming Zhang Jessica Ruth | 2001 | Journal of Transportation Engineering2001，，2： | 1 |
| 16 | Virologic, serologic, and biochemical outcomes through 2?years of treatment with entecavir and lamivudine in nucleoside-na?ve Chinese patients with chronic hepatitis B: a randomized, multicenter study显示文摘 | Guangbi Yao ChengWei Chen WeiLun Lu Hong Ren DeMing Tan YuMing Wang DaoZheng Xu Jessica Liu Dong Xu Cyril Llamoso | 2008 | Hepatology International2008，，4： | 1 |
| 17 | Isolation of a slowly adhering cell fraction containing- stem cells from murineskelet al muscle by the prepla- tetechnique显示文摘 | BurhanGharaibeh Aiping Lu Jessica Tebbets | 2008 | Nature protocols2008，3，9： | 1 |
| 18 | Modeling Indirect Statistics of Surface Roughness 显示文摘 | Lu Sun Zhanming Zhang Jessica Ruth | 2001 | Journal of Transportation Engineering2001，127，2： | 1 |
| 19 | Modeling indirect statistics of surface roughness 显示文摘 | Sun Lu Zhang Zhanming Ruth Jessica | 2001 | Journal of Transportation Engineering2001，127，2： | 1 |
| 20 | Synergistic Effects of Family History of Hepatocellular Carcinoma and Hepatitis B Virus Infection on Risk for Incident Hepatocellular Carcinoma显示文摘 | Rohit Loomba Jessica Liu Hwai–I. Yang Mei–Hsuan Lee Sheng–Nan Lu Li–Yu Wang Uchenna H. Iloeje San–Lin You David Brenner Chien–Jen Chen | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 1 |
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