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| 1 | Phase Ⅲ,randomized,double-blind,placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab-resistant,advanced breast cancer (BOLERO-3)显示文摘 | O' Regan R Ozguroglu M Andre F Toi M Jerusalem G Wilks S Isaacs C Xu B Masuda N Arena FP Yardley D Yap YS Mukhopadhyay P Douma S El-Hashimy M Taran T Sahmoud T Lebwohl D Gianni L | | 0，，15： | 1 |
| 2 | The effects of high hydrostatic pressure on bacteria显示文摘 | Chilton P Isaacs N S Mackey B | 1997 | High Pressure Research in the Biosciences and Biotechnology1997，229，： | 1 |
| 3 | Weak Hopf Algebras Corresponding to Uq显示文摘 | Aizawa N Isaac P S | 2003 | J Math Phys2003，44，11： | 1 |
| 4 | Weak Hopf algebras corresponding to Uq 显示文摘 | Aizawa N Isaac P S | 2003 | J Math Phys2003，44，11： | 1 |
| 5 | Coordinated Movement of Cytoplasmic and Transmembrene Domains of RyRI upon Gating 显示文摘 | Montserrat S Wei F Isaac N P | 2009 | PIeS Biol2009，7，4： | 1 |
| 6 | Biosynthetic re-quirements for the repair of membrane damage in pressure-treated Escherichia coli 显示文摘 | Chilton P Isaacs N S Teixeira P | 2001 | International Journal of Food Microbiology2001，71，1： | 1 |
| 7 | Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction显示文摘 | Sotoodehnia N Isaacs A de Bakker P I | | 0，，12： | 1 |
| 8 | Pattern and morphogenesis in skin 显示文摘 | Moore G P M Jackson N Isaacs K | 1998 | J Theor Biol1998，191，： | 1 |
| 9 | Pattern and morphogenesis in skin显示文摘 | Moore G P M Jackson N Isaacs K | 1998 | Theor Biol1998，191，： | 1 |
| 10 | Weak Hopf algebras corresponding to Uq(sln)显示文摘 | AIZAWA N ISAAC P S | 2003 | J Math Phys2003，44，： | 1 |
| 11 | Late recurrence of breast cancer presenting with esophageal dysmotility 显示文摘 | Isaacs P MacGillivray N Springett P | 1989 | J Clin Gastro- enterol1989，11，5： | 1 |
| 12 | Planning Mental Health Service for Children and Youth:Part Ⅱ-Findings of a Value-based Community Consultation Project 显示文摘 | Leslea P Isaac P Geoffrey N | 1997 | Eval Pro Plan1997，20，2： | 1 |
| 13 | Effect of transforming growth factor-betal on proliferation and death of rat prostatic cells显示文摘 | Martikainen P Kyprianou N Isaacs JT | 1990 | Endocrinology1990，127，6： | 1 |
| 14 | Weak Hopf algebras corresponding to Uq[sln]显示文摘 | Aizawa N Isaac P S | | 0，，： | 1 |
| 15 | Pattern and morphogenesis in skin 显示文摘 | Moore G P M Jackson N Isaacs K | 1998 | J Theoret Biol1998，191，： | 1 |
| 16 | Precise manipulation of chromosomes in vivo enables genome-wide codon replacement 显示文摘 | Isaacs F J Carr P A Wang H H Lajoie M J Sterling B Kraal L Tolonen A C Gianoulis T A Goodman D B Reppas N B | 2011 | Science2011，333，6040： | 1 |
| 17 | Hidden diversity of marine borderline lichens and a new order of fungi:Collemopsidiales(Dothideomyceta)显示文摘The fungal genus Collemopsidium comprises species that develop so-called borderline lichen symbioses with algae or cyanobacteria.Together with morphologically similar pyrenocarpous fungi it has been assigned to the family Xanthopyreniaceae.The adscription of this family to higher taxonomic ranks remain uncertain.Using sequence data of five nuclear genomic regions(nuLSU,nuSSU,tef1-α,rpb1 and rpb2)and onemitochondrial locus(mtSSU)we found that the studied representatives of this family are placed in the Dothideomyceta,yet relationships with the classes Dothideomycetes and Arthoniomycetes remain uncertain.We describe the new order Collemopsidiales to accommodate the genus Collemopsidium(paraphyletic as currently understood)and the lichenicolous genus Zwackhiomyces.Using five fungal fossils as calibrations points,we infer an age of c.230 Mya for the crown of Collemopsidiales.Based on two molecular markers,we also provide insight into the global diversity of marine species of the genus Collemopsidium.According to the species delimitation algorithm GMYC,c.26 putative species exist,far more than the six species recognized hitherto.We have confirmed this result by comparing the two alternative species models by means of Bayes factors,using path sampling and stepping-stone sampling algorithms to estimate the marginal likelihood of each model.Finally,our observations suggest rock-boring ability evolved in parallel in the different lineages within this group of fungi. | Sergio Pérez-Ortega Isaac Garrido-Benavent Martin Grube Rocío Olmo Asunción de los Ríos | 2016 | Fungal Diversity2016，，5： | 0 |
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