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| 1 | Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?显示文摘Our understanding of the microbial involvement in inflammatory bowel disease(IBD) pathogenesis has increased exponentially over the past decade. The development of newer molecular tools for the global assessment of the gut microbiome and the identification of nucleotide-binding oligomerization domain-containing protein 2 in 2001 and other susceptibility genes for Crohn's disease in particular has led to better understanding of the aetiopathogenesis of IBD. The microbial studies have elaborated the normal composition of the gut microbiome and its perturbations in the setting of IBD. This altered microbiome or 'dysbiosis' is a key player in the protracted course of inflammation in IBD. Numerous genome-wide association studies have identified further genes involved in gastrointestinal innate immunity(including polymorphisms in genes involved in autophagy: ATG16L1 and IGRM), which have helped elucidate the relationship of the local innate immunity with the adjacent luminal bacteria. These developments have also spurred the search for specific pathogens which may have a role in the metamorphosis of the gut microbiome from a symbiotic entity to a putative pathogenic one. Here we review advances in our understanding of microbial involvement in IBD pathogenesis over the past 10 years and offer insight into how this will shape our therapeutic management of the disease in the coming years. | Georgina L Hold Megan Smith Charlie Grange Euan Robert Watt Emad M El-Omar Indrani Mukhopadhya | 2014 | World Journal of Gastroenterology2014，20，5： | 21 |
| 2 | Regional changes of the severities of meteorological droughts and floods in India显示文摘南方亚洲人区域的最重要的 climatological 特征是季风的出现。与关于气候变化增加担心,理解如此的气候的条件的性质和可变性并且评估可能的未来变化的需要变得日益重要。这份报纸处理引起的长期的上面、下面正常的季风降水在印度延长气象学的干旱和洪水。越过包括可变气候的印度的五个区域为学习被选择。除了为单个区域的长期的趋势,长期的趋势也总体上为印度区域被计算。结果证明为季风降水的 intra 区域可变性大并且正在增加气象学的夏天干旱的数字。除了在半岛的印度区域,气象学的季风洪水被发现到处有否定长期的趋势。结果总的来说在印度和他们的空间可变性有关季风干旱和洪水的严厉的区域宽的长期的趋势建议通用结论。 | Indrani Pal Abir AI-Tabbaa | 2011 | Journal of Geographical Sciences2011，21，2： | 2 |
| 3 | Molecular characterization of antimicrobial multi-drug resistance in non-typhoidal Salmonellae from chicken and clam in Mangalore, India显示文摘Salmonella enterica has been documented as one of the leading causes of salmonellosis throughout the world and is most commonly associated with the consumption of contaminated food products. Thus, this research was aimed at studying the antimicrobial susceptibility pattern and detection of quinolone resistance in Salmonella spp isolated from food of animal origin. Thirty-six Salmonella isolates comprising 8 from poultry and 28 from seafood(clams) were identified, serotyped and characterized for their antimicrobial susceptibility against 10 different antibiotics. Plasmid DNA was isolated from all the isolates by alkaline lysis, quinolone resistant non-typhoidal S. Weltevreden were examined for mutation in the DNA gyrase coding gene. Among the 36 Salmonella isolates, 20 were S. weltevreden(8 from poultry and 12 from seafood) and 16 were S. Typhimurium(from seafood). All the isolates showed multiple resistance to nalidixic acid, tetracycline, co-trimoxazole and nitrofurantoin, but, interestingly, the isolates were 100% susceptible to ampicillin, chloramphenicol and gentamicin. Resistant isolates from the study carried the genes responsible for resistance to respective antibiotics. The strain S130 isolated in the study showed single point mutation,Asp87Gly, at position 87 in quinolone resistance determining region. It revealed mutation in quinolone resistance determining region as a cause for quinolone resistance in non-typhoidal Salmonellae. The occurrence of genes accountable for plasmid mediated resistance to quinolones(viz., qnrA, qnrB and qnrS) in plasmid of non-typhoidal Salmonellae isolates provides evidence for plasmid mediated quinolone resistance. | Yemisi Olukemi Adesiji Santhosh Kogaluru Shivakumaraswamy Vijaya Kumar Deekshit Girisha Shivani Kallappa Indrani Karunasagar | 2018 | The Journal of Biomedical Research2018，32，3： | 2 |
| 4 | Peroxyl radical scavenging activity of Gingkgo biloba extract Egb761 显示文摘 | Indrani M Lucia M Marie T D | 1995 | Biochemcal Pharmacology1995，49，11： | 1 |
| 5 | Embryo Implantation显示文摘 | Daniel D Indrani B Sudhandsu K | 2000 | Developmental Biology2000，223，2： | 1 |
| 6 | On the use of information criteria in analytic hierarchy process显示文摘 | INDRANI Basak | 2002 | European Journal of Operational Research2002，141，1： | 1 |
| 7 | The current status of sheep pox disease显示文摘 | Bhanuprakash V Indrani B K Hosamani M | 2006 | Comp Immunot Microbiol Infect Dis2006，29，1： | 1 |
| 8 | Monsoon Rainfall Ex- treme Indices and Tendencies from 1954-2003 in Kerala,India显示文摘 | Indrani P Abir Al-Tahbaa | 2011 | Climatic Change2011，106，3： | 1 |
| 9 | Pregnancy in women with epilepsy:preliminary results of Kerala registry of epilepsy and pregnancy显示文摘 | Indrani L Devi GC | 2001 | Neurology India2001，49，1： | 1 |
| 10 | On Some Predictors of Times to Failure of Censored Items in Progressively Censored samples 显示文摘 | Indrani Basak Prasanta Basak Balakrishnan N | 2006 | Computational Statistics & Data Analysis2006，50，5： | 1 |
| 11 | Freeze Drying Technique for Microencapsulation of Garcinia Fruit Extract and its Effect on Bread Quality显示文摘 | Ezhilarasi P N Indrani D Jena B S | 2013 | Journal of Food Engineering2013，117，4： | 1 |
| 12 | On the Use of Information Ceiteria in Analytic Hierarchy Pro- cess显示文摘 | Indrani Basak | 2002 | Journal of Operational Research2002，，141： | 1 |
| 13 | Modulation of experimental colon tumor genesis by types and amounts of dietary fatty acids显示文摘 | RAO C V HIROSE Y INDRANIE C | 2001 | Cancer Res2001，61，： | 1 |
| 14 | Reduction of acrylamide formation in sweet bread with L-asparaginase treatment 显示文摘 | Mohan Kumar N S Shimray C A Indrani D | 2014 | Food Bioprocess Technology2014，，7： | 1 |
| 15 | Modulation of experimental colon tumorigenesis by types and amounts of dietary fatty acids显示文摘 | Rao CR Hirose Y Indranie C | 2001 | Cancer Res2001，61，5： | 1 |
| 16 | The current status of sheep pox disease显示文摘 | BHANUPRAKASH V INDRANI B K HOSAMANI M | 2006 | Corap Immunol Microb2006，29，2： | 1 |
| 17 | Stereocon- trolled synthesis of anticancer /3-1actams via the staudinger reaction 显示文摘 | Bimal K B Indrani B Frederick F B | 2005 | Bioorg Med Chore2005，13，11： | 1 |
| 18 | Clinical Significance of Inactivated Glycogen Synthase Kinase 3β in HPV ‐Associated Cervical Cancer: Relationship with W nt/β‐ C atenin Pathway Activation显示文摘 | Gayatri Rath Poonam Jawanjal Sudha Salhan Manoharan Nalliah Indrani Dhawan | 2015 | Am J Reprod Immunol2015，，5： | 1 |
| 19 | Perinatal outcome after multi- fetal pregnancy reduction 显示文摘 | Suresh S Indrani S Thangavel G | 2008 | Indian J Pediatr2008，75，9： | 1 |
| 20 | Trends in seasonal precipitation extremes – An indicator of ‘climate change’ in Kerala, India显示文摘 | Indrani Pal Abir Al-Tabbaa | 2009 | Journal of Hydrology2009，，1： | 1 |
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