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| 1 | Antimicrobial activities of the tissue extracts of Babylonia spirata Linnaeus,1758 (Mollusca:Gastropoda) from Thazhanguda,southeast coast of India显示文摘Objective:To investigate the antimicrobial activity of the tissue extracts of Babylonia spirata(B.spirala)against nine bacterial and three fungal patliogeiis.Methods:Crude extract of gastropod was tested for inhibition of bacterial and fungal growth.Antibacterial assay was carried out by disc diffusion method and in vitro antifungal activity was determined against Czapex Dox agar.The antimicrobial activity was measured accordingly based on the inhibition zone around the disc impregnated with gastropod extract.Molecular size of muscle protein was determined using sodium dodecyl sulfate polyacrylamide gel electrophoresis(SDS-PAGE).And fourier transform infrared spectroscopy(FT1R)spectro photometry analysis was also studied.Results:The maximum inhibition zone(12 mm)was observed against Pseudomonas aeruginosa in the crude ethanol extract of B.spirata and the minimum inhibition zone(2 mm)was noticed against Staphylococcus aureus in the crude methanol extract of B.spirala.Water extract of B.spirala showed the highest activity against Vibrio parahaemolyticus,Staphylococcus aureus and Candida albicans.Ethanol,acetone,methanol,chloroform and water extracts showed antimicrobial activity against almost all the bacteria and fungus.Compared with water extracts,ethanol and methanol extracts showed higher activity against all pathogens.The molecular weight of protein of the gastropod sample ranged from 2-110 kDa on SDS-PAGE.FTIR analysis revealed the presence of bioactive compounds signals at different ranges.Conclusions:The research shows that the great medicinal value of the gastropod muscle of B.spirata may be due to high quality of antimicrobial compounds. | Periyasamy N Srinivasan M Balakrishnan S | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，1： | 4 |
| 2 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 3 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 4 | Integrated routing and storage for messaging applications in mobile ad hoc networks显示文摘 | Nain D Petigara N Balakrishnan H | 2004 | Mobile Networks and Applications2004，9，6： | 1 |
| 5 | Estimation for the three-parameter lognormM distribution based on progressively censored data 显示文摘 | Basak P Basak I and Balakrishnan N | 2009 | Computational Statistics and Data Analysis2009，53，： | 1 |
| 6 | OpenFlow: enabling innovation in campus networks 显示文摘 | McKeown N Anderson T Balakrishnan H | 2008 | ACM SIGCOMM Computer Communication Review2008，38，2： | 1 |
| 7 | Open Flow:enabling innovation in campus networks显示文摘 | Mc Keown N Anderson T Balakrishnan H | 2008 | ACM SIGCOMM CCR2008，38，2： | 1 |
| 8 | Prevalence and incidence of swxually transmitted infections among South Indians at increased risk of HIV infection显示文摘 | Kumarasamy N Balakrishnan P Venkatesh KK | 2008 | AIDS Patient Care STDS2008，22，8： | 1 |
| 9 | Blends of polycarbonate with unmodified and maleic anhydride grafted ABS: fracture mechanics显示文摘 | Balakrishnan S Neelakantan N R | 1999 | Journal of Materials Science1999，34，： | 1 |
| 10 | Point and Interval estimation for Gaussian distribution based on progressively type-lI censored samples 显示文摘 | Balakrishnan N Kannan N Lin C T and Ng H K T | 2003 | IEEE Transactions on Reliability2003，52，： | 1 |
| 11 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 12 | Heavy atom tunneling in chemical reactions: Study of H + LiF collisions显示文摘 | WECKA P F BALAKRISHNAN N | 2005 | J Chem Phys2005，122，23： | 1 |
| 13 | Achieving product variety through optimal choice of module variations 显示文摘 | Chakravarty A K Balakrishnan N | 2001 | IIE Transactions2001，33，7： | 1 |
| 14 | Analyzing unreplicated factorial experiments: a review with some new proposals显示文摘 | Hamada M and Balakrishnan N | 1998 | Statistica Sinica1998，8，： | 1 |
| 15 | Open-Flow:enabling innovation in campus networks显示文摘 | McKEOWN N ANDERSON T BALAKRISHNAN H | 2008 | ACM SIGCOMM Computer Communication Review2008，38，2： | 1 |
| 16 | Turbulent flow com- putations on a hybrid Cartesian point distribution using mesh显示文摘 | MUNIKRISHNA N BALAKRISHNAN N | 2011 | Computers Fluids2011，40，： | 1 |
| 17 | Fisher information in hybrid censored data显示文摘 | Sangun P Balakrishnan N ZHENG Gang | 2008 | Statistics and Probability Letters2008，78，： | 1 |
| 18 | OpenFlow: enabling innovation in campus networks显示文摘 | McKEOWN N ANDERSON T BALAKRISHNAN H | 2008 | ACM Special Interest Group on Data Communication Computer Communication Review2008，38，2： | 1 |
| 19 | Mis-speeification analyses of gamma and Wiener degradation processes显示文摘 | TSAI C C TSENG S T BALAKRISHNAN N | 2011 | Jour- nal of Statistical Planning and Inference2011，141，12： | 1 |
| 20 | Confidence intervals for quantiles and tolerance intervals based on ordered ranked set samples显示文摘 | BALAKRISHNAN N LI T | | 0，，： | 1 |
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