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| 1 | Wheat ear carbon assimilation and nitrogen remobilization contribute significantly to grain yield显示文摘The role of wheat ears as a source of nitrogen(N)and carbon(C) in the grain filling process has barely been studied. To resolve this question, five wheat genotypes were labeled with15N-enriched nutrient solution. N remobilization and absorption were estimated via the nitrogen isotope composition of total organic matter and Rubisco. Gas exchange analyses showed that ear photosynthesis contributed substantially to grain filling in spite of the great loss of C due to respiration. Of the total kernel N, 64.7% was derived from the N acquired between sowing and anthesis, while the remaining35.3% was derived from the N acquired between anthesis and maturity. In addition, 1.87 times more N was remobilized to the developing kernel from the ear than from the flag leaf. The higher yielding genotypes showed an increased N remobilization to the kernel compared to the lower yielding genotypes. Inaddition, the higher yielding genotypes remobilized more N from the ears to the kernel than the lower yielding genotypes,while the lower yielding genotypes remobilized more N from the flag leaf to the kernel. Therefore, the ears contribute significantly toward fulfilling C and N demands during grain filling. | Bangwei Zhou Maria Dolores Serret Abdelhalim Elazab Jordi Bort Pie José Luis Araus Iker Aranjuelo álvaro Sanz-Sáez | 2016 | Journal of Integrative Plant Biology2016，58，11： | 9 |
| 2 | Al_2O_3基Ni-Cu双金属催化剂上乙酰丙酸氢解(英)显示文摘Inexpensive γ-alumina-based nickel-copper bimetallic catalysts were studied for the hydrogenolysis of levulinic acid,a key platform molecule for biomass conversion to biofuels and other valued chemicals,into γ-valerolactone as a first step towards the production of 2-methyltetrahydrofurane.The activities of both monometallic and bimetallic catalysts were tested.Their textural and chemical characteristics were determined by nitrogen physisorption,elemental analysis,temperature-programmed ammonia desorption,and temperature-programmed reduction.The monometallic nickel catalyst showed high activity but the highest bγ-product production and significant amounts of carbon deposited on the catalyst surface.The copper monometallic catalyst showed the lowest activity but the lowest carbon deposition.The incorporation of the two metals generated a bimetallic catalyst that displayed a similar activity to that of the Ni monometallic catalyst and significantly low bγ-product and carbon contents,indicating the occurrence of important synergetic effects.The influence of the preparation method was also examined by studying impregnated- and sol-gel-derived bimetallic catalysts.A strong dependency on the preparation procedure and calcination temperature was observed.The highest activity per metal atom was achieved using the sol-gel-derived catalyst that was calcined at 450 ℃.High reaction rates were achieved;the total levulinic acid conversion was obtained in less than 2 h of reaction time,yielding up to 96%γ-valerolactone,at operating temperature and pressure of 250 ℃ and 6.5 MPa hydrogen,respectively. | Iker Obregón Eriz Corro Urko Izquierdo Jesus Requies Pedro L.Arias | 2014 | 催化学报2014，35，5： | 8 |
| 3 | Photosynthetic and Molecular Markers of CO_2-mediated Photosynthetic Downregulation in Nodulated Alfalfa显示文摘提高的 CO2 在潜在的生长在长期的实验并且这样在潜在的网光合作用导致减少到减小。这个过程作为光合的 downregulation 被知道。参数为检测 CO2 环境适应是最敏感的定义上没有协议。为了调查 CO2 的最敏感的光合、分子的标记,环境适应,提高的 CO2 的效果,和联系提高的温度在与不同 Sinorhizobium meliloti 紧张接种的苜蓿工厂被分析。工厂(Medicago sativa L。cv。 | Alvaro Sanz-Sez Gorka Erice Iker Aranjuelo Ricardo Aroca Juan Manuel Ruíz-Lozano Jone Aguirreolea Juan Jos Irigoyen Manuel Sanchez-Diaz | 2013 | Journal of Integrative Plant Biology2013，55，8： | 3 |
| 4 | Food groups, diet quality and colorectal cancer risk in the Basque Country显示文摘BACKGROUND The results obtained to date concerning food groups,diet quality and colorectal cancer(CRC)risk vary according to criteria used and the study populations.AIM To study the relationships between food groups,diet quality and CRC risk,in an adult population of the Basque Country(North of Spain).METHODS This observational study included 308 patients diagnosed with CRC and 308 ageand sex-matched subjects as controls.During recruitment,dietary,anthropometric,lifestyle,socioeconomic,demographic and health status information was collected.Adherence to the dietary recommendations was evaluated utilizing the Healthy Eating Index for the Spanish Diet and the MedDietScore.Conditional logistic regressions were used to evaluate the associations of food group intakes,diet quality scores,categorized in tertiles,with CRC risk.RESULTS The adjusted models for potential confounding factors showed a direct association between milk and dairy products consumption,in particular high-fat cheeses[odds ratio(OR)third tertile vs first tertile=1.87,95%confidence intervals(CI):1.11-3.16],and CRC risk.While the consumption of fiber-containing foods,especially whole grains(OR third tertile vs first tertile=0.62,95%CI:0.39-0.98),and fatty fish(OR third tertile vs first tertile=0.53,95%CI:0.27-0.99)was associated with a lower risk for CRC.Moreover,higher MD adherence was associated with a reduced CRC risk in adjusted models(OR third tertile vs first tertile=0.40,95%CI:0.20-0.80).CONCLUSION Direct associations were found for high-fat cheese,whereas an inverse relation was reported for fiber-containing foods and fatty fish,as well as adherence to a Mediterranean dietary pattern. | Iker Alegria-Lertxundi Carmelo Aguirre Luis Bujanda Francisco J Fernandez Francisco Polo JoseMªOrdovas MªCarmen Etxezarraga Inaki Zabalza Mikel Larzabal Isabel Portillo Marian M de Pancorbo Koldo Garcia-Etxebarria Ana MªRocandio Marta Arroyo-Izaga | 2020 | World Journal of Gastroenterology2020，26，28： | 3 |
| 5 | Relationship between vegetation diversity and soil functional diversity in native mixed-oak forests显示文摘 | Gloria Rodríguez-Loinaz Miren Onaindia Ibone Amezaga Iker Mijangos Carlos Garbisu | 2007 | Soil Biology and Biochemistry2007，，1： | 3 |
| 6 | 用Lewis酸或Brnsted酸催化剂和N_2汽提法使木糖脱水为糠醛(英文)显示文摘The activity of Lewis (Nb2O5) and Br nsted (Amberlyst 70) acid catalysts for the cyclodehydration of xylose to furfural was studied. The nature of the acidity resulted in significant changes in the reaction mechanism. Lewis acid sites promote the formation of xylulose, while Br nsted acid sites are required to further dehydrate the sugar to furfural. Amberlyst 70 in water/toluene at 175 ℃ showed lower activity but gave a higher furfural yield. Using N2 as the stripping agent considerably improved the furfural yield and product purity in the stripped stream. Catalyst stability was also studied. | Iker AGIRREZABAL-TELLERIA Cristina GARCíA-SANCHO Pedro MAIRELES-TORRES Pedro Luis ARIAS | 2013 | 催化学报2013，34，7： | 2 |
| 7 | An update on the molecular biology of glioblastoma,with clinical implications and progress in its treatment显示文摘Glioblastoma multiforme(GBM)is the most aggressive and common malig-nant primary brain tumor.Patients with GBM often have poor prognoses,with a median survival of∼15 months.Enhanced understanding of the molecular biology of central nervous system tumors has led to modifications in their classifications,the most recent of which classified these tumors into new categories and made some changes in their nomenclature and grading system.This review aims to give a panoramic view of the last 3 years’findings in glioblastoma characterization,its heterogeneity,and current advances in its treatment.Several molecular parameters have been used to achieve an accurate and personalized characterization of glioblastoma in patients,including epigenetic,genetic,transcriptomic and metabolic features,as well as age-and sex-related patterns and the involvement of several noncoding RNAs in glioblastoma progression.Astrocyte-like neural stem cells and outer radial glial-like cells from the subven-tricular zone have been proposed as agents involved in GBM of IDH-wildtype origin,but this remains controversial.Glioblastoma metabolism is characterized by upregulation of the PI3K/Akt/mTOR signaling pathway,promotion of the gly-colytic flux,maintenance of lipid storage,and other features.This metabolism also contributes to glioblastoma’s resistance to conventional therapies.Tumor heterogeneity,a hallmark of GBM,has been shown to affect the genetic expresion,modulation of metabolic pathways,and immune system evasion.GBM’s aggressive invasion potential is modulated by cell-to-cell crosstalk within the tumor microenvironment and altered expressions of specific genes,such as ANXA2,GBP2,FN1,PHIP,and GLUT3.Nevertheless,the rising number of active clinical trials illustrates the efforts to identify new targets and drugs to treat this malignancy.Immunotherapy is still relevant for research purposes,given the amount of ongoing clinical trials based on this strategy to treat GBM,and neoantigen and nucleic acid-based vaccines are gaining importance due to their antitumoral activity by inducing the immune response.Furthermore,there are clinical trials focused on the PI3K/Akt/mTOR axis,angiogenesis,and tumor heterogeneity for developing molecular-targeted therapies against GBM.Other strategies,such as nanodelivery and computational models,may improve the drug pharmacokinetics and the prognosis of patients with GBM. | Elena Verdugo Iker Puerto MiguelÁngel Medina | 2022 | Cancer Communications2022，42，11： | 2 |
| 8 | Effects of fertilization and tillage on soil biological parameters显示文摘 | Iker Mijangos Roberto Perez | 2006 | Enzyme and Microbial Technology2006，40，： | 1 |
| 9 | Effects of fertilization and tillage on soil biological parameters 显示文摘 | Iker M Roberto P Isabel A | 2006 | Enzyme and Microbial Technology2006，40，： | 1 |
| 10 | Filtering of high modal frequencies for stable real-time explicit integration of deformable objects using finite element method显示文摘 | IKER A BASIL F JONAS S | | 0，，2： | 1 |
| 11 | Determination of Johnson-Cook Parameters from Machining Simulations 显示文摘 | Shrot A B/iker M | 2012 | Computational Materials Science (S0927-0256)2012，52，1： | 1 |
| 12 | Determinants of health promoting lifestyle behaviors in rural older women显示文摘 | Pullen C Wa Iker S N Fiandt K | 2001 | Fam Community Health2001，24，2： | 1 |
| 13 | Effects of anodized aluminium surface parameters on the long-term adhesion of silicone structural glazing sealants 显示文摘 | Pierre Descamps Jean Iker Andreas T | 1996 | Construction and Building Materials1996，10，7： | 1 |
| 14 | Matrix metalloproteinase‐10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair显示文摘 | Oihane Garcia‐Irigoyen Simone Carotti Maria U. Latasa Iker Uriarte Maite G. Fernández‐Barrena Maria Elizalde Raquel Urtasun Umberto Vespasiani‐Gentilucci Sergio Morini Jesús M. Banales William C. Parks Jose A. Rodriguez Josune Orbe Jesús Prieto Jose A. Pá | 2014 | Liver Int2014，，7： | 1 |
| 15 | Thin films stress extraction using micromachined structures and wafer curvature measurements 显示文摘 | Laconte J Iker F Jorez S | 2004 | Microelectronic Engineering2004，76，： | 1 |
| 16 | Energy detection technique for adative spec- trum sensing显示文摘 | IKER S PAULO S R | 2015 | IEEE Transactions on Communications2015，63，3： | 1 |
| 17 | An overview of technical challenges and advances of inductive wireless power transmission显示文摘 | Mayordomo Iker Drager Tobias Spies Peter | 2013 | Proceedings of the IEEE2013，101，6： | 1 |
| 18 | Prepa- ration of C-LiFePO4/polypyrrole Lithium rechargeable cathode by consecutive potential steps electrodeposition 显示文摘 | Iker Boyano J Alberto Blazcluez Iratxede Meatza | 2010 | Journal of Power Sources2010，195，53： | 1 |
| 19 | Study into the validity of an accelerated test method for tensile adhesion sample by immersion into water at elevated temperatures 显示文摘 | Iker J Descamps P Tilmant G | 1992 | Revue Technique du Batiment et des Contractions Industrielles1992，23，143： | 1 |
| 20 | Ae2 a,b -Deficient Mice Develop Antimitochondrial Antibodies and Other Features Resembling Primary Biliary Cirrhosis显示文摘 | January T. Salas Jesús M. Banales Sarai Sarvide Sergio Recalde Alex Ferrer Iker Uriarte Ronald P.J. Oude Elferink Jesús Prieto Juan F. Medina | 2008 | Gastroenterology2008，，5： | 1 |
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