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| 1 | Effect of exhaust gas recirculation and intake pre-heating on performance and emission characteristics of dual fuel engines at part loads显示文摘Achieving simultaneous reduction of NOx,CO and unburned hydrocarbon(UHC) emissions without compromising engine performance at part loads is the current focus of dual fuel engine research.The present work focuses on an experimental investigation conducted on a dual fuel(diesel-natural gas) engine to examine the simultaneous effect of inlet air pre-heating and exhaust gas recirculation(EGR) ratio on performance and emission characteristics at part loads.The use of EGR at high levels seems to be unable to improve the engine performance at part loads.However,it is shown that EGR combined with pre-heating of inlet air can slightly increase thermal efficiency,resulting in reduced levels of both unburned hydrocarbon and NOx emissions.CO and UHC emissions are reduced by 24% and 31%,respectively,The NOx emissions decrease by 21% because of the lower combustion temperature due to the much inert gas brought by EGR and decreased oxygen concentration in the cylinder. | A.Paykani R.Khoshbakhti Saray M.T.Shervani-Tabar A.Mohammadi-Kousha | 2012 | Journal of Central South University2012，19，5： | 6 |
| 2 | BRCAA1基因克隆、染色体定位与特征性分析显示文摘 | 崔大祥 高天文 金桂秋 孙天白 Akinori Sarai | 2003 | 自然杂志2003，25，6： | 3 |
| 3 | Transgenic and genome-edited fruits: background, constraints, benefits, and commercial opportunities显示文摘Breeding has been used successfully for many years in the fruit industry,giving rise to most of today’s commercial fruit cultivars.More recently,new molecular breeding techniques have addressed some of the constraints of conventional breeding.However,the development and commercial introduction of such novel fruits has been slow and limited with only five genetically engineered fruits currently produced as commercial varieties—virus-resistant papaya and squash were commercialized 25 years ago,whereas insect-resistant eggplant,non-browning apple,and pink-fleshed pineapple have been approved for commercialization within the last 6 years and production continues to increase every year.Advances in molecular genetics,particularly the new wave of genome editing technologies,provide opportunities to develop new fruit cultivars more rapidly.Our review,emphasizes the socioeconomic impact of current commercial fruit cultivars developed by genetic engineering and the potential impact of genome editing on the development of improved cultivars at an accelerated rate. | Maria Lobato-Gomez Seanna Hewitt Teresa Capell Paul Christou Amit Dhingra Patricia Sarai Giron-Calva | 2021 | Horticulture Research2021，8，1： | 2 |
| 4 | An overview of resistance to chemotherapy in osteosarcoma and future perspectives显示文摘Osteosarcoma(OS)is the most common type of bone sarcoma.Despite the availability of multimodal treatment with surgery and chemotherapy,the clinical results remain unsatisfactory.The main reason for the poor outcomes in patients with OS is the development of resistance to methotrexate,cisplatin,doxorubicin,and ifosfamide.Molecular and cellular mechanisms associated with resistance to chemotherapy include DNA repair and cell-cycle alterations,enhanced drug efflux,increased detoxification,resistance to apoptosis,autophagy,tumor extracellular matrix,and angiogenesis.This versatility of cells to generate chemoresistance has motivated the use of anti-angiogenic therapy based on tyrosine kinase inhibitors.This approach has shown that other therapies,along with standard chemotherapy,can improve responses to therapy in patients with OS.Moreover,microRNAs may act as predictors of drug resistance in OS.This review provides insight into the molecular and cellular mechanisms involved in the development of resistance during the treatment of OS and discusses promising novel therapies(e.g.,afatinib and palbociclib)for overcoming resistance to chemotherapy in OS. | Dorian Yarih Garcia-Ortega Sara Aileen Cabrera-Nieto Haydee Sarai Caro-Sanchez Marlid Cruz-Ramos | 2022 | Cancer Drug Resistance2022，5，3： | 2 |
| 5 | 无针喷注器注射博来霉素治疗瘢痕疙瘩和肥厚性瘢痕的一项初步研究显示文摘Background: Numerous treatment modalities have been used to treat keloids and hypertrophic scars, but the optimal treatment has not been established. Objectiv e: The aim of this study was to determine the efficacy and safety of intralesion al jet injection of bleomycin as therapy for keloids and hypertrophic scars that are unresponsive to intralesional steroid injection. Methods: The study include d 14 patients with 15 keloids or hypertrophic scars that had not responded to a minimum of three intralesional injections of triamcinolone acetonide. Multiple j et injections of 0.1 ml of bleomycin (1.5 IU/ml) were administered to each lesio n, with injection sites spaced 0.5 mm apart. Injections were repeated each month . Scar height was measured, and scar pliability and erythema were scored at base line and then monthly during the treatment and followup periods. Patients’self -assessments of subjective symptoms (pruritus and pain)were also scored. Clinic al improvementwas defined primarily on the basis of scar height reduction (perce ntage reduction from baseline), and was classified using the following scale: co mplete flattening (100%), highly significant flattening (> 90%), significant f lattening (75-90%), moderate flattening (50-75%), and minimal flattening (< 50%). Preand post-treatment mean values for scar height, scar pliability, eryt hema, pruritus and pain were statistically compared. Results: The number of sess ions required to successfully treat the lesions ranged from two to six. Eleven l esions (73.3%) showed complete flattening, one (6.7%) showed highly significan t flattening, two (13.3%) showed significant flattening, and one scar (6.7%) s howed moderate flattening. The mean scar height was significantly lower, and the mean scores for scar pliability and erythema were significantly better at the e nd of treatment (P < 0.001, P < 0.001 and P < 0.001, respectively). The mean sco res for pruritus and pain also improved significantly (P < 0.001 and P=0.01, res pectively). The observed side-effects were hyperpigmentation (four lesions) and skin atrophy (three lesions). No recurrences were noted during follow up (mean duration of 19 months). Conclusions: Intralesional jet injection of bleo mycin is an effective and safe method of treating keloids and hypertrophic scars that are unresponsive to intralesional steroid therapy. | Saray Y GüleT 冯义国 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，1： | 2 |
| 6 | 获得性穿通性皮肤病:22例患者临床病理学特征研究 | Saray Y. Sekin D. Bileziki B. 任建文 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，0，10： | 2 |
| 7 | Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes显示文摘 | R. Kodera K. Shikata H. U. Kataoka T. Takatsuka S. Miyamoto M. Sasaki N. Kajitani S. Nishishita K. Sarai D. Hirota C. Sato D. Ogawa H. Makino | 2011 | Diabetologia2011，，4： | 2 |
| 8 | 多层螺旋CT计算心室容积的准确性及最佳层厚选择显示文摘目的(1)确定Simpson方法计算心室容积的最佳层厚;(2)评价多层螺旋CT计算心室容积的准确性。方法采用多层螺旋CT(东芝Aquilion)扫描系统对14个人的左室铸型和15个右室铸型进行扫描。分别以2.0、3.5、5.0、7.0及10.0mm层厚重建左、右心室短轴多平面重组(multiplanarreformattedimage,MPR)图像。采用标准Simpson法计算左、右心室铸型的容积。心室铸型的实际容积通过铸型排除水的容量来计算。结果各层厚计算的心室容积均高估相应心室的实际容积[左心室高估值介于(3.21±5.95)ml至(12.58±8.56)ml之间,右心室高估值介于(10.22±8.45)ml至(23.91±12.24)ml之间]。各层厚计算的心室容积均与相应的实际心室容积高度相关(左心室r值均>0.97,右心室r值均>0.95);心室容积的高估程度与选择的层厚呈显著正相关(左心室r=0.998,右心室r=0.996)。当层厚降至5mm时,计算的心室容积对实际容积的高估值与2mm层厚相比不再差异有统计学意义。结论采用多排Simpson法计算左、右心室容积时,5mm层厚是最有效率的层厚。MSCT可以准确计算左、右心室容积。 | 崔炜 Takeshi Kondo Hirofumi Anno 郭玉印 Takahisa Sato Masayoshi Sarai Hitoshi Shinozaki Satoshi Kakizawa Atsushi Sugiura Keita Oshima Kazuhiro Katada Hitoshi Hishida | 2005 | 中华放射学杂志2005，39，12： | 2 |
| 9 | Formability of friction stir processed low carbon steels used in shipbuilding显示文摘The stretch formability of a low carbon steel processed by friction stir processing(FSP) was studied under biaxial loading condition applied by a miniaturized Erichsen test. One-pass FSP decreased the ferritic grain size in the processed zone from 25 m to about 3 m, which also caused a remarkable increase in strength values without considerable decrease in formability under uniaxial loading. A coarse-grained(CG) sample before FSP reflected a moderate formability with an Erichsen index(EI) of 2.73 mm. FSP slightly decreased the stretch formability of the sample to 2.66 mm. However, FSP increased the required punch load(FEI)due to the increased strength by grain refinement. FSP reduced considerably the roughness of the free surface of the biaxial stretched samples with reduced orange peel effect. The average roughness value(Ra) decreased from 2.90 in the CG sample down to about 0.65 m in fine-grained(FG) sample after FSP.It can be concluded that the FG microstructure in low carbon steels sheets or plates used generally in shipbuilding provides a good balance between strength and formability. | D.M. Sekban S.M. Akterer O. Saray Z.Y. Ma G. Purcek | 2018 | Journal of Materials Science & Technology2018，34，1： | 2 |
| 10 | Multislice computed tomographic characteristics of coronary lesions in acute coronary syndromes显示文摘 | Motoyama S Kondo T Sarai M | 2007 | J Am Coll Cardiol2007，50，： | 1 |
| 11 | Effect of whey protein purity and glycerol content upon physical properties of edible films manufactu- red therefrom 显示文摘 | Oscar L R Isabel R SaraI S | 2013 | Food Hydrocolloids2013，30，： | 1 |
| 12 | Multislice computed tomographic characteristics of coronary lesions in acute coronary syndromes显示文摘 | Motoyama S Kondo T Sarai M | 2007 | J Am Coll Cardiol2007，50，4： | 1 |
| 13 | Elective versus provisional intra-aortic balloon pumping in high-risk percutaneous transluminal coronary angioplasty显示文摘 | Sarais C Pagnotta P | 2003 | Am Heart J2003，145，4： | 1 |
| 14 | Antigenic properties of porcine teschovirus 1 (PTV-1) Talfan strain and molecular strat- egy for serotyping of PTVs 显示文摘 | Kaku Y Murakami Y Sarai A | 2007 | Arch Virol2007，152，5： | 1 |
| 15 | Multislice computed tomo graphic characteristics oi' coronary lesions in acute coronary syn dromes显示文摘 | Motoyama S Kondo T Sarai M | 2007 | J Am Coil Cardiol2007，50，31： | 1 |
| 16 | Resolution of apoptosis in atherosclerotic plaque by dietary modification and statin therapy显示文摘 | Hartung D Sarai M Petrov A | | 0，，12： | 1 |
| 17 | Genetic reclassification of porcine enteroviruses 显示文摘 | Kaku Y Sarai A Murakami Y | 2001 | J Gen Virol2001，82，2： | 1 |
| 18 | Real value prediction of solvent accessibility from amino acid sequence 显示文摘 | Ahmad S Gromiha MM Sarai A | 2003 | Proteins2003，50，： | 1 |
| 19 | Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome显示文摘 | Motoyama S Sarai M Harigaya H | 2009 | J Am Coil Cardiol2009，54，1： | 1 |
| 20 | Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome显示文摘 | Motoyama S Sarai M Harigaya H | 2009 | J Am Coil Cardiol2009，54，1： | 1 |
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