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| 1 | Sensitive detection and accurate monitoring of Plasmodium vivax parasites on routine complete blood count using automatic blood cell analyzer (DxH800TM)显示文摘 | H. K.LEE S. I.KIM H.CHAE M.KIM J.LIM E. J.OH Y.KIM Y. J.PARK W.LEE K.HAN | 2012 | International Journal of Laboratory Hematology2012，，： | 1 |
| 2 | 查看详情显示文摘 | Yuan Y Thomé I.Kim S.H Chen D Beyer A Bonnamour J Zuidema E Chang S Bolrn C | | 0，，： | 1 |
| 3 | pH‐ and thermal characteristics of graft hydrogels based on chitosan and poly(dimethylsiloxane)显示文摘 | In YoungKim Seon JeongKim Mi‐SeonShin Young MooLee Dong‐IcShin Sun I.Kim | 2002 | J Appl Polym Sci2002，，13： | 1 |
| 4 | Electronic Post-Compensation of WDM Transmission impairments显示文摘 | X. Li X. Chen G. Goldfarb E.Mateo I.Kim F.Yaman G.Li | | 0，，02： | 1 |
| 5 | Blockade of GITR–GITRL interaction maintains Treg function to prolong allograft survival显示文摘 | James I.Kim Samsher B.Sonawane Major K.Lee Seoung‐HoonLee Patrick E.Duff Daniel J.Moore Matthew R.O'Connor Moh‐MohLian ShaopingDeng YongwonChoi HeidiYeh Andrew J.Caton James F.Markmann | 2010 | Eur J Immunol2010，，5： | 1 |
| 6 | Establishing a baseline phase behavior in magnetic resonance imaging to determine normal vs. abnormal iron content in the brain显示文摘 | E. MarkHaacke MuhammadAyaz AsadullahKhan Elena S.Manova BharaniKrishnamurthy LakshmanGollapalli CarloCiulla I.Kim FloydPetersen WolffKirsch | 2007 | J Magn Reson Imaging2007，，2： | 1 |
| 7 | Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8^(+)T cell responses显示文摘The antitumor capabilities of agonistic anti-4-1BB mAbs have made them an attractive target for tumor immunotherapy.However,the adverse side effects associated with agonist antibodies have hindered their clinical development.Here,we aimed to study the immune-related adverse events of repeated doses and long-term use of agonistic anti-4-1BB mAbs.We show that chronic activation of 4-1BB signals induced the accumulation of IFN-γ-producing PD-1^(+)CD8^(+)T cells in the secondary lymphoid organs of tumor-bearing mice by increasing the number of dividing CD8^(+)T cells,which was beneficial for suppressing tumor growth in the early phase of anti-4-1BB induction.However,repeated exposure to anti-4-1BB mAbs led to granuloma development in tumor-draining lymph nodes(TDLNs)of mice due to recruitment and accumulation of macrophages via the CD8^(+)T cell-IFN-γaxis.This was accompanied by excessive lymph node swelling,which impaired the sequential activation of CD8^(+)T cells.Our data provide insights into the immune-related adverse events of long-term agonist 4-1BB antibody dosing,which should be considered during the clinical development of immunomodulating therapy. | Seon-Hee Kim Rohit Singh Chungyong Han Eunjung Cho Yu I.Kim Don G.Lee Young H.Kim Sang Soo Kim Dong Hoon Shin Hye Jin You Hyeon-Woo Lee Byoung S.Kwon Beom K.Choi | 2021 | Cellular & Molecular Immunology2021，18，8： | 0 |
| 8 | The redshift distribution of BL Lacs and FSRQs显示文摘Flat spectrum radio quasars(FSRQs) and BL Lacertae objects(BL Lacs) are powerful jet producing active galactic nuclei associated with supermassive black holes accreting at high and low Eddington rates, respectively. Based on the Millennium Simulation, Gardner & Done have predicted their redshift distribution by appealing to ideas from the spin paradigm in a way that exposes a need for a deeper discussion on three interrelated issues:(1) an overprediction of BL Lacs compared to FSRQs;(2) a difference in FSRQ and BL Lac distributions;(3) a need for powerful but different jets at separated cosmic times. Beginning with Gardner & Done's determination of Fermi observable FSRQs based on the distribution of thermal accretion across cosmic time from the Millennium Simulation, we connect FSRQs to BL Lacs by way of the gap paradigm for black hole accretion and jet formation to address the above issues in a unified way. We identify a physical constraint in the paradigm for the numbers of BL Lacs that naturally leads to separate peaks in time for different albeit powerful jets. In addition, we both identify as puzzling and ascribe physical significance to a tail end in the BL Lac curve versus redshift that is unseen in the redshift distribution for FSRQs. | David Garofalo Chandra B.Singh Dylan T.Walsh Damian J.Christian Andrew M.Jones Alexa Zack Brandt Webster Matthew I.Kim | 2019 | Research in Astronomy and Astrophysics2019，19，1： | 0 |
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