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| 1 | Effect of seawater on incident plane P and SV waves at ocean bottom and engineering characteristics of offshore ground motion records off the coast of southern California, USA显示文摘The effect of seawater on vertical ground motions is studied via a theoretical method and then actual offshore ground motion records are analyzed using a statistical method. A theoretical analysis of the effect of seawater on incident plane P and SV waves at ocean bottom indicate that on one hand, the affected frequency range of vertical ground motions is prominent due to P wave resonance in the water layer if the impedance ratio between the seawater and the underlying medium is large, but it is greatly suppressed if the impedance ratio is small; on the other hand, for the ocean bottom interface model selected herein, vertical ground motions consisting of mostly P waves are more easily affected by seawater than those dominated by SV waves. The statistical analysis of engineering parameters of offshore ground motion records indicate that:(1) Under the infl uence of softer surface soil at the seafl oor, both horizontal and vertical spectral accelerations of offshore motions are exaggerated at long period components, which leads to the peak spectral values moving to a longer period.(2) The spectral ratios(V/H) of offshore ground motions are much smaller than onshore ground motions near the P wave resonant frequencies in the water layer; and as the period becomes larger, the effect of seawater becomes smaller, which leads to a similar V/H at intermediate periods(near 2 s). These results are consistent with the conclusions of Boore and Smith(1999), but the V/H of offshore motion may be smaller than the onshore ground motions at longer periods(more than 5 s). | Diao Hongqi Hu Jinjun Xie Lili | 2014 | Earthquake Engineering and Engineering Vibration2014，13，2： | 24 |
| 2 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020，13，6： | 23 |
| 3 | Exosome-encapsulated miR-505 from ox-LDL-treated vascular endothelial cells aggravates atherosclerosis by inducing NET formation显示文摘Neutrophil extracellular traps(NETs)play an important role in the pathological process of atherosclerosis(AS).This study aims to evaluate whether exosomes from oxidized low-density lipoprotein(ox-LDL)-treated vascular endothelial cells(VECs)aggravate AS by inducing NET formation.Exosomes from the peripheral blood of healthy donors and AS patients(namely NC-EXO and AS-EXO,respectively)and exosomes from human umbilical vein endothelial cells(HUVECs)treated without or with ox-LDL(namely normal EXO and ox-LDL-EXO,respectively)were isolated,identified,and co-cultured with neutrophils from peripheral blood of healthy donors.NET formation was evaluated by immunofluorescence staining and determining the content of cell-free DNA and myeloperoxidase-DNA complex.Dual-luciferase reporter assay,chromatin immunoprecipitation assay,quantitative reverse transcription polymerase chain reaction,and western blot analysis were performed to explore the underlying mechanisms.We found that AS-EXO and ox-LDLEXO in duced NET release from n eutrophils.Meeh a nistically,ox-LDL treatment in HUVECs might activate the NF-κB pathway,which transcriptionally activates miR-505,and then the exosome-encapsulated high miR-505 expression targeted and inhibited SIRT3 in neutrophils,thereby inducing reactive oxygen species(ROS)level increase and NET release by neutrophils.Further in vivo experiments showed that ox-LDLEXO accelerated AS progression in AS mice.In summary,exosome-encapsulated miR-505 from ox-LDLtreated VECs aggravates AS by inducing NET formation. | Li Chen Liqun Hu Qing Li Jian Ma Hongqi Li | 2019 | Acta Biochimica et Biophysica Sinica2019，51，12： | 11 |
| 4 | Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces macrophage infiltration to attenuate atherosclerosis显示文摘Atherosclerosis(AS)is the main pathological basis for ischemic cardiovascular and cerebrovascular diseases.Mesenchymal stem cell(MSC)-derived exosomes have the potential to alleviate AS,while the underlying mechanism remains unclear.Here,we aimed to investigate the mechanism of MSC-derived exosomes in AS.The AS mouse model was prepared by feeding ApoE–/–mice with high-fat diet.AS mice were administered with MSC-derived exosomes,and the atherosclerotic plaque area was analyzed by Oil Red O staining.Mouse RAW264.7 macrophages were incubated with MSC-derived exosomes.The macrophage infiltration,macrophage proportion,and cell migration were estimated by immunohistochemistry,flow cytometry,or Transwell assay.The relationship between miR-21a-5p and kruppel-like factor 6(KLF6)or extracellular signal-regulated protein kinases 2(ERK2)was verified by luciferase reporter assay.We found that MSC-derived exosomes promoted M2 polarization of macrophages and reduced plaque area and macrophage infiltration in AS mice.miR-21a-5p overexpression caused an increase of M2 macrophages in RAW264.7 cells and led to a decrease in migration of RAW264.7 cells.Moreover,both KLF6 and ERK2 are the targets of miR-21a-5p.MSC-derived exosomes containing miR-21a-5p promoted M2 polarization of RAW264.7 cells by suppressing KLF6 expression.MSC-derived exosomes containing miR-21a-5p inhibited migration of RAW264.7 cells through inhibiting the ERK1/2 signaling pathway.In conclusion,MSC-derived exosomes containing miR-21a-5p promote macrophage polarization and reduce macrophage infiltration by targeting KLF6 and ERK1/2 signaling pathways,thereby attenuating the development of AS.Thus,MSC-derived exosomes may be a promising treatment for AS. | Jian Ma Li Chen Xiang Zhu Qing Li Liqun Hu Hongqi Li | 2021 | Acta Biochimica et Biophysica Sinica2021，53，9： | 7 |
| 5 | Comparison of nonhuman primates identified the suitable model for COVID-19显示文摘Identification of a suitable nonhuman primate(NHP)model of COVID-19 remains challenging.Here,we characterized severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in three NHP species:Old World monkeys Macaca mulatta(M.mulatta)and Macaca fascicularis(M.fascicularis)and New World monkey Callithrix jacchus(C.jacchus).Infected M.mulatta and M.fascicularis showed abnormal chest radiographs,an increased body temperature and a decreased body weight.Viral genomes were detected in swab and blood samples from all animals.Viral load was detected in the pulmonary tissues of M.mulatta and M.fascicularis but not C.jacchus.Furthermore,among the three animal species,M.mulatta showed the strongest response to SARS-CoV-2,including increased inflammatory cytokine expression and pathological changes in the pulmonary tissues.Collectively,these data revealed the different susceptibilities of Old World and New World monkeys to SARS-CoV-2 and identified M.mulatta as the most suitable for modeling COVID-19. | Shuaiyao Lu Yuan Zhao Wenhai Yu Yun Yang Jiahong Gao Junbin Wang Dexuan Kuang Mengli Yang Jing Yang Chunxia Ma Jingwen Xu Xingli Qian Haiyan Li Siwen Zhao Jingmei Li Haixuan Wang Haiting Long Jingxian Zhou Fangyu Luo Kaiyun Ding Daoju Wu Yong Zhang Yinliang Dong Yuqin Liu Yinqiu Zheng Xiaochen Lin Li Jiao Huanying Zheng Qing Dai Qiangming Sun Yunzhang Hu Changwen Ke Hongqi Liu Xiaozhong Peng | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 6 | Near infrared spectral and polarization imaging observation of coronal emission lines during the 2008 total solar eclipse显示文摘During the 2008 total solar eclipse, the coronal emission lines were observed by using optical fibre spectrometric and polarization imaging system in near infrared waveband. The profiles of the coronal emission lines including Fe XIII 10747 , 10798 and He I 10830 were obtained with dispersion of 0.5 /pix. The intensity of Fe XIII 10747 remained unchanged in the two different coronal regions while the intensity of He I 10830 varied considerably in the two coronal locations no matter whether the prominence appeared or not. The coronal polarization images were observed at Fe XI 7892 with a bandpass of 30 in a series of exposure times. | BAO XingMing ZHANG ZhiYong DENG Jian HU KeLiang XUAN WeiJia LIU YangBing ZHANG HongQi DENG YuanYong WANG DongGuang WANG XiaoFan | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，11： | 5 |
| 7 | Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells显示文摘 | Nengquan Sheng Li Yan Weiqiang You Gewen Tan Jianfeng Gong Hongqi Chen Yi Yang Landian Hu Zhigang Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，10： | 4 |
| 8 | IPSO-based hybrid approaches for reliability-redundancy allocation problems显示文摘The problem of maximizing system reliability through component reliability choices and component redundancy is called reli-ability-redundancy allocation problem(RAP),and it is a difficult but realistic nonlinear mixed-integer optimization problem.For the RAP,we pay attention to an improved particle swarm optimization(IPSO),and introduce four hybrid approaches for combining the IPSO with other conventional search techniques,such as harmony search(HS)and LXPM(a real coded GA).The basic structure of the hybrid approaches includes two phases.After devising an initial solution by the HS or LXPM technique in the first phase,the IPSO performs an optimal search in the next phase.In addition,a new procedure by using golden search,named GS,is developed for further improving the solutions obtained by IPSO.Consequently,four ISPO-based hybrid approaches are proposed including HS-IPSO,LXPM-IPSO,HS-IPSO-GS,and LXPM-IPSO-GS.In order to validate the per-formance of proposed approaches,five nonlinear mixed-integer RAPs are investigated where both the number of redundancy components and the corresponding component reliability in each subsystem are to be decided simultaneously.As shown,the proposed approaches are all superior in terms of both optimal solutions and robustness to those by IPSO.Especially,the pro-posed LXPM-IPSO-GS has shown more excellent performance than other typical approaches in the literature. | ZHANG HongQi HU XiangTao SHAO XiaoDong LI ZiCheng WANG YuHui | 2013 | Science China(Technological Sciences)2013，56，11： | 2 |
| 9 | Preparation and luminescent properties of (Ca 1- x ,Sr x )S:Eu 2+ red-emitting phosphor for white LED显示文摘 | Yunsheng Hu Weidong Zhuang Hongqi Ye Shusheng Zhang Ying Fang Xiaowei Huang | 2004 | Journal of Luminescence2004，，3： | 2 |
| 10 | A multi-step induced strategy to fabricate core-shell Pt-Ni alloy as symmetric electrocatalysts for overall water splitting显示文摘Devising an electrocatalyst with brilliant efficiency and satisfactory durability for hydrogen production is of considerable demand,especially for large-scale application.Herein,we adopt a multi-step consequential induced strategy to construct a bifunctional electrocatalyst for the overall water splitting.Graphene oxide(GO)was used as a carbon matrix and in situ oxygen source,which was supported by the octahedral PtNi alloy to form the PtxNiy-GO precursor.When calcinating in Ar atmosphere,the oxygen in GO induced the surface segregation of Ni from the PtNi octahedron to form a core-shell structure of Ptx@Niy.Then,the surface-enriched Ni continuously induced the reformation of C in reduced graphene oxide(rGO)to enhance the degree of graphitization.This multi-step induction formed a nanocatalyst Pt_(x)@Ni_(y)-rGO which has very high catalytic efficiency and stability.By optimizing the feeding ratio of PtNi(Pt:Ni=1:2),the electrolytic overall water splitting at 10 mA·cm^(-2) can be driven by an electrolytic voltage of as low as 1.485 V,and hydrogen evolution reaction(HER)only needs an overpotential of 37 mV in 1.0 M KOH aqueous solution.Additionally,the catalyst exhibited consistent existence form in both HER and oxygen evolution reaction(OER),which was verified by switching the anode and cathode of the cell in the electrolysis of water.This work provides a new idea for the synthesis and evaluation of the bifunctional catalysts for water splitting. | Wenjuan Xu Jinfa Chang Yinggang Cheng Hongqi Liu Jifan Li Yongjian Ai Zenan Hu Xinyue Zhang Yiming Wang Qionglin Liang Yang Yang Hongbin Sun | 2022 | Nano Research2022，15，2： | 1 |
| 11 | A novel red phosphor for white light emitting diodes显示文摘 | Hu Yunsheng Zhuang Weidong Ye Hongqi | 2005 | Journal of Alloys and Compounds2005，390，12： | 1 |
| 12 | A novel red phosphor for white light emitting diodes显示文摘 | HU Yunsheng ZHUANG Weidong YE Hongqi | 2005 | Alloys and Compounds2005，390，1： | 1 |
| 13 | Synthesis of fluorocarbon-modified poly(acrylic add) in supercritical carbon dioxide显示文摘 | Hongqi Hu Tao He Mingcai Chen | 2002 | Polymer2002，43，： | 1 |
| 14 | Fast motion estimation algorithm for H.264/AVC based on centered prediction显示文摘H.264/AVC video coding standard can achieve roughly half of the bit-savings over MPEG2 and MPEG4 for a given quality. However, this comes at a cost in considerably increased complexity at the encoder and thus increases the difficulty in hardware implementation. The high redundancy that exists between the successive frames of a video sequence makes it possible to achieve a high data compression ratio. Motion estimation (ME) plays an important role in motion compensated video coding. A fast motion estimation algorithm for H.264/AVC is proposed based on centered prediction, called centered prediction based fast mixed search algorithm (CPFMS). It makes use of the spatial and temporal correlation in motion vector (MV) fields and feature of all-zero blocks to accelerate the searching process. With the initialized searching point prediction, adaptive search window changing and searching direction decision, CPFMS is provided to reduce computation in block-matching process. The experimental results show that the speed of CPFMS is nearly 12 times of FS with a negligible peak signal-noise ratio (PSNR) loss. Also, the efficiency of CPFMS outperforms some popular fast algorithms such as hybrid unsymmetrical cross multi-hexagongrid search and a novel multidirectional gradient descent search evidently. | Wei Zhou Zhemin Duan Hongqi Hu | 2010 | Journal of Systems Engineering and Electronics2010，21，6： | 1 |
| 15 | A novel red phosphor for white light emitting diodes显示文摘 | Yunsheng Hu Weidong Zhuang Hongqi Ye Donghui Wang Shusheng Zhang Xiaowei Huang | 2004 | Journal of Alloys and Compounds2004，，1： | 1 |
| 16 | A novel red phosphor for white light emitting diodes显示文摘 | Hu Yunsheng Zhuang Weidong Ye Hongqi | 2005 | Journal of Al- loys and Compounds2005，390，： | 1 |
| 17 | A novel red phosphor for white light emitting diodes显示文摘 | Yunsheng Hu Weidong Zhuang Hongqi Ye Donghui Wang Shusheng Zhang Xiaowei Huang | 2004 | Journal of Alloys and Compounds2004，，1： | 1 |
| 18 | Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRPα-CD47 axis显示文摘Dear Editor,Cancer cells often upregulate the expression of ligands for the inhibitory immune checkpoints receptor to escape anti-tumor immunity1. Targeting inhibitory immune checkpoints has become one of the most promising anticancer therapeutic inventions. Infiltration of myeloid cells, especially phagocytic cells, to tumors is often associated with chemotherapy resistance and progression of various cancer types. Phagocytosis of cancer cells is the major mechanism for these myeloid cells-mediated antitumor activity. However, many types of cancer cells express high level of ‘don’t eat me’ signals on the cell surface to escape the phagocytic cells-mediated antitumor immunity. | Zhiqiang Wu Linjun Weng Tengbo Zhang Hongling Tian Lan Fang Hongqi Teng Wen Zhang Jing Gao Yun Hao Yaxu Li Hu Zhou Ping Wang | 2019 | Cell Research2019，29，6： | 1 |
| 19 | Preparation and luminescent properties of (Ca1-x Srx)S:Eu^2+ red-emitting phosphor for white LED 显示文摘 | HU YUNSHENG ZHUANG WE IDONG YE HONGQI | 2005 | Lumin2005，111，3： | 1 |
| 20 | A novel red phosphor for white light emitting diodes显示文摘 | Yunsheng Hu Weidong Zhuang Hongqi Ye | 2005 | Journal of Alloys and Compounds2005，390，12： | 1 |
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