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| 1 | Nutritional risk index as a predictor of postoperative wound complications after gastrectomy显示文摘AIM:To investigate the correlation between the nutritional risk index (NRI) and postoperative wound complications.METHODS:From January 2008 through June 2008,669 patients who underwent curative gastrectomy for gastric cancer were included in a retrospective study.Medical records of consecutive patients were collected and analyzed to determine postoperative wound complication rates.The NRI was assessed on the fifth postoperative day and other possible risk factors for the incidence of wound complications were analyzed to identify the factors affecting postoperative wound complications.Patients with other postoperative complications were excluded from the study.RESULTS:On the 5th postoperative day,the NRI showed a malnutrition rate of 84.6% among postoperative patients.However,postoperative wound complications occurred in only 66/669 (9.86%) patients.Of the patients with wound complications,62/66 (94%) belonged to the malnourished group (NRI < 97.5),and 4/66 (6%) patients to the non-malnourished group (NRI ≥ 97.5).The only factor correlated with wound complications was the NRI on the 5th postoperative day (odds ratio of NRI ≥ 97.5 vs NRI < 97.5:0.653;95% confidence interval:0.326-0.974;P=0.014) according to univariate analysis as well as multivariate analysis.CONCLUSION:This study suggests that malnutrition immediately after surgery may play a significant role in the development of wound complications. | Cheong Ah Oh Dae Hoon Kim Seung Jong Oh Min Gew Choi Jae Hyung Noh Tae Sung Sohn Jae Moon Bae Sung Kim | 2012 | World Journal of Gastroenterology2012，18，7： | 25 |
| 2 | Association between Helicobacter pylori status and metachronous gastric cancer after endoscopic resection显示文摘AIM To investigate the effect of Helicobacter pylori(H. pylori) status test and H. pylori eradication on the occurrence of metachronous gastric cancer(MGC) after endoscopic submucosal dissection(ESD) of early gastric cancer(EGC) and risk factors of MGC. METHODS The authors retrospectively reviewed the medical records of 433 patients(441 lesions) who underwent ESD for EGC from January 2005 to January 2015 in Yeungnam University Hospital. Patients were categorized into two groups; the H. pylori tested group(n = 257) and the H. pylori non-tested group(n = 176) based on performance of H. pylori status test after ESD of EGC. The H. pylori tested group was further categorized into three subgroups based on H. pylori status; the H. pylori-eradicated subgroup(n = 120), the H. pylori-persistent subgroup(n = 42), and the H. pylori-negative subgroup(n = 95). Incidences of MGC and risk factors of MGC were identified.RESULTS Median follow-up duration after ESD was 30.00 mo(range, 6-107 mo). Total 15 patients developed MGC during follow-up. MGC developed in 11 patients of the H. pylori tested group(7 in the H. pylori-negative subgroup, 3 in the H. pylori-eradicated subgroup, and 1 in the H. pylori-persistent subgroup) and 4 patients of the H. pylori non-tested group(P > 0.05). The risk factors of MGC were endoscopic mucosal atrophy in the H. pylori tested group and intestinal metaplasia in all patients. CONCLUSION H. pylori eradication and H. pylori status test seems to have no preventive effect on the development of MGC after ESD for EGC. The risk factors of MGC development were endoscopic mucosal atrophy in the H. pylori tested group alone and intestinal metaplasia in all patients. | Sung Bum Kim Si Hyung Lee Seung Il Bae Yo Han Jeong Se Hoon Sohn Kyeong Ok Kim Byung Ik Jang Tae Nyeun Kim | 2016 | World Journal of Gastroenterology2016，22，44： | 8 |
| 3 | 基于线激光锁相热成像的芯片裂纹成像检测显示文摘提出一种用于半导体芯片表面裂纹瞬时成像检测的线激光锁相热成像新技术。该技术系统由线扫描激光源、高速红外照相机及控制计算机组成,由线激光束扫描目标芯片表面并利用红外相机测量热波传播。提出新型无基线裂纹可视化算法,裂纹可导致热波阻挡现象,故被自动可视化和诊断,不依赖由目标芯片原始状态所获得的基线数据。对芯片在制造过程中产生细微裂纹进行研究,实验证明热成像新技术可对宽度为几十微米的裂纹进行可视化。 | 许颖 王青原 罗聪聪 Hoon Sohn | 2020 | 激光与光电子学进展2020，57，6： | 6 |
| 4 | Epidermal growth factor upregulates Skp2/Cks1 and p27^(kip1) in human extrahepatic cholangiocarcinoma cells显示文摘AIM:To evaluate the expression status of S-phase kinase-associated protein 2(Skp2)/cyclin-dependent kinases regulatory subunit 1(Cks1)and p27kip1,and assess the prognostic significance of Skp2/Cks1 expression with p27kip1in patients with extrahepatic cholangiocarcinoma.METHODS:Seventy-six patients who underwent curative resection for histologically confirmed extrahepatic cholangiocarcinoma at our institution from December1994 to March 2008 were enrolled.Immunohistochemical staining for Skp2,Cks1,p27kip1,and Ki67,along with other relevant molecular biologic experiments,were performed.RESULTS:By Cox regression analyses,advanced age(>65 years),advanced AJCC tumor stage,poorly differentiated histology,and higher immunostaining intensity of Skp2 were identified as independent prognostic factors in patients with extrahepatic cholangiocarcinoma.Exogenous epidermal growth factor(EGF,especially 0.1-10 ng/mL)significantly increased the proliferation indices by MTT assay and the mRNA levels of Skp2/Cks1 and p27kip1in SNU-1196,SNU-1079,and SNU-245 cells.The protein levels of Skp2/Cks1(from nuclear lysates)and p27kip1(from cytosolic lysate)were also significantly increased in these cells.There were significant reductions in the protein levels of Skp2/Cks1and p27kip1(from nuclear lysate)after the treatment of LY294002.By chromatin immunoprecipitation assay,we found that E2F1 transcription factor directly binds to the promoter site of Skp2.CONCLUSION:Higher immunostaining intensity of Skp2/Cks1 was an independent prognostic factor for patients with extrahepatic cholangiocarcinoma.EGF upregulates the mRNA and protein levels of Skp2/Cks1and p27kip1via the PI3K/Akt pathway and direct binding of E2F1 transcription factor with the Skp2 promoter. | Ja-yeon Kim Hong Joo Kim Jung Ho Park Dong Il Park Yong Kyun Cho Chong Il Sohn Woo Kyu Jeon Byung Ik Kim Dong Hoon Kim Seoung Wan Chae Jin Hee Sohn | 2014 | World Journal of Gastroenterology2014，20，3： | 4 |
| 5 | Trends in the eradication rates of Helicobacter pylori infection for eleven years显示文摘AIM:To evaluate the trends in the eradication rate of Helicobacter pylori(H.pylori) over the past 11 years in a single center.METHODS:This retrospective study covered the period from January 2000 to December 2010.We evaluated 5746 patients diagnosed with gastric ulcers(GU),duodenal ulcers(DU),GU + DU,or nonpeptic ulcers associated with an H.pylori infection.We treated them annually with the 2 wk standard first-line triple regimen,proton pump inhibitor(PPI) + amoxicilin + clarithromycin(PAC;PPI,clarithromycin 500 mg,and amoxicillin 1 g,all twice a day).The follow-up test was performed at least 4 wk after the completion of the 2 wk standard H.pylori eradication using the PAC regimen.We also assessed the eradication rates of 1 wk second-line therapy with a quadruple standard regimen(PPI b.i.d.,tripotassium dicitrate bismuthate 300 mg q.i.d.,metronidazole 500 mg t.i.d.,and tetracycline 500 mg q.i.d.) after the failure of the first-line therapy.Statistical analysis was performed with 95%CI for the differences in the annual eradication rates.RESULTS:A total of 5746 patients [2333 males(58.8%),1636 females(41.2%);mean age of males vs females 51.31 ± 13.1 years vs 52.76 ± 13.6 years,P < 0.05,total mean age 51.9 ± 13.3 years(mean ± SD)] were investigated.Among these patients,1674 patients were excluded:35 patients refused treatment;18 patients ceased H.pylori eradication due to side effects;1211 patients had inappropriate indications for H.pylori eradication,having undergone stomach cancer operation or chemotherapy;and 410 patients did not undergo the follow-up.We also excluded 103 patients who wanted to stop eradication treatment after only 1 wk due to poor compliance or the side effects mentioned above.Finally,we evaluated the annual eradication success rates in a total of 3969 patients who received 2 wk first-line PAC therapy.The endoscopic and clinical findings in patients who received the 2 wk PAC were as follows:gastric ulcer in 855(21.5%);duodenal ulcer in 878(22.1%);gastric and duodenal ulcer in 124(3.1%),erosive,atrophic gastritis and functional dyspepsia in 2055(51.8%);and other findings(e.g.,MALToma,patients who wanted to receive the therapy even though they had no abnormal endoscopic finding) in 57(0.5%).The overall eradication rate of the 2 wk standard firstline triple regimen was 86.5%.The annual eradication rates from 2000 to 2010 were 86.7%,85.4%,86.5%,83.3%,89.9%,90.5%,88.4%,84.5%,89.1%,85.8%,and 88.3%,sequentially(P = 0.06).No definite evidence of a significant change in the eradication rate was seen during the past eleven years.The eradication rates of second-line therapy were 88.9%,82.4%,85%,83.9%,77.3%,85.7%,84.4%,87.3%,83.3%,88.9%,and 84%(P = 0.77).The overall eradication rate of 1 wk quadruple second-line therapy was 84.7%.There was no significant difference in the eradication rate according to the H.pylori associated diseases.CONCLUSION:This study showed that there was no trend change in the H.pylori eradication rate over the most recent 11 years in our institution. | Jai Hoon Yoon Gwang Ho Baik Kyoung Min Sohn Dae Yong Kim Yeon Soo Kim Ki Tae Suk Jin Bong Kim Dong Joon Kim Jin Bae Kim Woon Geon Shin Hak Yang Kim Il Hyun Baik Hyun Joo Jang | 2012 | World Journal of Gastroenterology2012，18，45： | 3 |
| 6 | Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial显示文摘 | Seung-Yong Jeong Ji Won Park Byung Ho Nam Sohee Kim Sung-Bum Kang Seok-Byung Lim Hyo Seong Choi Duck-Woo Kim Hee Jin Chang Dae Yong Kim Kyung Hae Jung Tae-You Kim Gyeong Hoon Kang Eui Kyu Chie Sun Young Kim Dae Kyung Sohn Dae-Hyun Kim Jae-Sung Kim Hye Seu | 2014 | Lancet Oncology2014，，7： | 3 |
| 7 | Neoadjuvant Chemoradiotherapy Affects the Indications for Lateral Pelvic Node Dissection in Mid/Low Rectal Cancer with Clinically Suspected Lateral Node Involvement: A Multicenter Retrospective Cohort Study显示文摘 | Heung-Kwon Oh Sung-Bum Kang Sung-Min Lee Soo Young Lee Myoung Hun Ihn Duck-Woo Kim Ji Hoon Park Young Hoon Kim Kyung Ho Lee Jae-Sung Kim Jin Won Kim Jee Hyun Kim Tae-Young Chang Sung-Chan Park Dae Kyung Sohn Jae Hwan Oh Ji Won Park Seung-Bum Ryoo Seung-Yo | 2014 | Annals of Surgical Oncology2014，，： | 2 |
| 8 | Changes in Postoperative Recurrence and Prognostic Risk Factors for Patients with Gastric Cancer who Underwent Curative Gastric Resection during Different Time Periods显示文摘 | Dae Hoon Kim Su Mi Kim Jung Kuk Hyun Min Gew Choi Jae Hyung Noh Tae Sung Sohn Jae Moon Bae Sung Kim | 2013 | Annals of Surgical Oncology2013，，7： | 2 |
| 9 | Acidic properties of nickel sulfate supported on TiO2-ZrO2 and calalytic activity for acid eatalysis显示文摘 | Sohn Jong Rack Lee Si Hoon | 2004 | Applied Catalysis A: General2004，266，1： | 1 |
| 10 | A bayesian probabilistic approach for structure damage detection显示文摘 | Hoon Sohn Kincho H Law | 1997 | Earthquake Engineering and Structural Dynamics1997，26，： | 1 |
| 11 | Comparison of the belly board device method and the distended bladder method for reducing irradiated small bowel volumes in preoperative radiotherapy of rectal cancer patients显示文摘 | Tae Hyun Kim Eui Kyu Chie Dae Yong Kim Sung Yong Park Kwan Ho Cho Kyung Hae Jung Young Hoon Kim Dae Kyung Sohn Seung-yong Jeong Jae-Gahb Park | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，3： | 1 |
| 12 | Wavelet-based active sensing for delamination detection in composite structures显示文摘 | | 2004 | Smart Material and Structures2004，13，： | 1 |
| 13 | New solid superacid catalyst prepared by doping ZrO2 with Ce and modifying with sulfate and its catalytic activity for acid catalysis显示文摘 | Jong Rack Sohn Si Hoon Lee Jun Seob Lim | 2006 | Catalysis Today2006，116，14： | 1 |
| 14 | Damage diagnosis using time series analysis of vibration signals 显示文摘 | Sohn Hoon Farrar Charles R | 2001 | Smart Materials and Structures2001，10，： | 1 |
| 15 | Steam reforming of biomass gasification tar using benzene as a model compound over various Ni supported metal oxide catalysts显示文摘 | Park Hyun Ju Park Sung Hoon Sohn Jung Min | | 0，，01： | 1 |
| 16 | A New Suggestion for the Radiation Target Volume After a Subtotal Gastrectomy in Patients With Stomach Cancer显示文摘 | Heerim Nam Do Hoon Lim Sung Kim Won Ki Kang Tae Sung Sohn Jae Hyung Noh Yong Il Kim Chan Hyung Park Chul Keun Park Yong Chan Ahn Seung Jae Huh | 2008 | International Journal of Radiation Oncology Biology Physics2008，，2： | 1 |
| 17 | An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach显示文摘 | Sung Kim Do Hoon Lim Jeeyun Lee Won Ki Kang John S. MacDonald Chan Hyung Park Se Hoon Park Se-Hoon Lee Kihyun Kim Joon Oh Park Won Seog Kim Chul Won Jung Young Suk Park Young-Hyuck Im Tae Sung Sohn Jae Hyung Noh Jin Seok Heo Yong Il Kim Chul Keun Park Keu | 2005 | International Journal of Radiation Oncology Biology Physics2005，，5： | 1 |
| 18 | Vibration reduction of high-speed railway bridges by adding size-adjusted vehicles显示文摘 | Jeong-Ryol Shin Yun-Kyu An Hoon Sohn Chung-Bang Yun | 2010 | Engineering Structures2010，，9： | 1 |
| 19 | Bortezomib and the Increased Incidence of Herpes Zoster in Patients with Multiple Myeloma显示文摘 | Seok Jin Kim Kihyun Kim Byung Soo Kim Hyo-Jin Lee Hawk Kim Na-Ri Lee Seung-Hyun Nam Jung Hye Kwon Hyo Jung Kim Sang Kyun Sohn Jong-Ho Won Jae Hoon Lee Cheolwon Suh Sung-Soo Yoon Hye Jin Kim Inho Kim Young-Rok Do Won-Sik Lee Young-Don Joo Ho Jin Shin | 2008 | Clinical Lymphoma & Myeloma2008，，4： | 1 |
| 20 | Time reversal active sensing for health monitoring of a composite plate显示文摘 | Hyun Woo Park Hoon Sohn Kincho H Law et al | 2007 | Journal of Sound and Vibration2007，302，： | 1 |
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