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| 1 | Adult neural stem cells in the mammalian central nervous system显示文摘神经干细胞(NSC ) 不仅在胚胎的发展期间而且在所有哺乳动物的种类的成年大脑是在场的,包括人。在 vivo 的干细胞壁龛建筑学使成年 NSC 能连续地在整个生活在特定的大脑区域产生功能的神经原。成年神经发生过程服从于动态规定由各种各样生理,病理学并且药理学刺激。Multipotent 成年 NSC 也看起来内在地塑料,对基因编程顺从在正常区别期间,并且到 epigenetic reprograming 在进 pluripotency 的 de 区别期间。增加的证据建议成年 NSC 显著地在生理、病理学的条件下面贡献专业化神经功能。充分理解成年 NSC 的生物学将提供关键卓见进病原学和主要大脑混乱的潜在的治疗学的干预。这里,我们在哺乳动物的中央神经系统的成年 NSC 上考察最近的进步,包括他们在癌症和再生药的身份,壁龛,功能,粘性,和新兴的角色上的话题。 | Dengke K Ma | 2009 | Cell Research2009，19，6： | 35 |
| 2 | Organic amendments increase corn yield by enhancing soil resilience to climate change显示文摘A 22-year field experiment was conducted in Gongzhuling, Jilin province, China to investigate corn yield response to fertilization practice. Compared to an unfertilized control(CK), all fertilization treatments, including inorganic nitrogen fertilizer only(N), balanced inorganic fertilizers(NPK), NPK plus corn straw(SNPK), and NPK plus farmyard manure(MNPK), resulted in significant increases in corn yield. However, only organic matter amendments sustained increasing yield trends, with annual rates of 0.137 and 0.194 t ha-1for the SPNK and MNPK treatments, respectively(P < 0.05). During the 22 years, the daily mean, maximum and minimum temperatures increased by 0.50, 0.53, and 0.46 °C per decade, whereas precipitation displayed no significant change but showed large seasonal variation. According to a regression analysis, increased air temperature exerted positive effects on corn yields under the SNPK and the MNPK treatments. Under both treatments,soil organic carbon contents and soil nutrient availabilities increased significantly compared to their initial levels in 1990, whereas soil bulk density and total porosity changed slightly under the two treatments, which showed higher soil water storage than other treatments. In contrast, significant increases in soil bulk density and decreases in soil total porosity and soil nutrient availability were observed under the CK, N and NPK treatments. The contributions of soil fertility to corn yield were 28.4%, 37.9%, 38.4%, 39.0%,and 42.9% under CK, N, NPK, SNPK, and MNPK treatments, respectively, whereas climate changes accounted for 27.0%, 14.6%, 12.4%, 11.8%, and 10.8%. These results indicate that, in Northeast China, organic matter amendments can mitigate negative and exploit positive effects of climate change on crop production by enhancing soil quality. | Zhenwei Song Hongjun Gao Ping Zhu Chang Peng Aixing Deng Chengyan Zheng Md Abdul Mannaf Md Nurul Islam Weijian Zhang | 2015 | The Crop Journal2015，3，2： | 8 |
| 3 | Seasonal variability of the zooplankton community in the southwest of the Huanghai Sea (Yellow Sea) Cold Water Mass显示文摘Samples were collected with a plankton net in the four seasonal cruises during 2006-2007 to study the seasonal variability of the zooplankton community in the southwest part of Huanghai Sea Cold Water Mass (HSCWM, Yellow Sea Cold Water Mass). The spatial and temporal variations of zooplankton species composition, biomass, abundance and biodiversity were examined. A total of 122 zooplankton species and 30 pelagic larvae were identified in the four cruises. Calanus sinicus and Aidanosagitta crassa were the most dominant species, and Themisto gaudichaudi and Euphausia pacifica were widely distributed in the HSCWM area. The spatial patterns of non-gelatinous zooplankton (removing the high water content groups) were similar to those of the total zooplankton biomass in autumn, but different significantly in the other three seasons. The seasonal means of zooplankton biomass in spring and summer were much higher than that in autumn and winter. The total zooplankton abundance averaged 283.5 ind./m^3 in spring (highest), 192.5 ind./m^3 in summer, 165.5 ind./m^3 in autumn and 65.9 ind./m^3 in winter (lowest), and the non-gelatinous groups contributed the most total abundance. Correlation analysis suggests that the non-gelatinous zooplankton biomass and abundance had a significant positive correlation in the whole year, but the relationship was insignificant between the total zooplankton biomass and abundance in spring and summer. The diversity index H of zooplankton community averaged 1.88 in this study, which was somewhat higher than historical results. Relatively low diversity in summer was related to the high dominance of Calanus sinicus, probably due to the strongest effect of the HSCWM in this season. | LIU Ping SONG Hongjun WANG Xiao WANG Zongling PU Xinming ZHU Mingyuan | 2012 | Acta Oceanologica Sinica2012，31，4： | 8 |
| 4 | Expression and intercellular trafficking of the VP22 protein of CVI988/Rispens vaccine strain of Marek’s disease virus显示文摘The viral protein 22 (VP22) in the tegument of Marek’s disease virus serotype 1 (MDV-1) plays an im-portant role in cell-to-cell spread and viral propagation. Antiserum against the carboxyl terminus of VP22 was prepared by immunizing mice with recombinant VP22 expressed in E. coli, and used to in-vestigate its expression in chicken embryo fibroblast (CEF) cells infected with different MDV-1 strains. At an infection dose of PFU=50, intercellular trafficking of the VP22 into the nuclei of the surrounding receipt cells was detected as early as 3 hours post infection. By 6 hours after infection (before viral plague formation), the protein was detected in the whole nuclei of the recipient cells with no difference among MDV-1 strains CVI988/Rispens, GA and RB1B. Intra-nuclear accumulation of the VP22 protein was further increased when the viral plagues started to form. These results indicate that, albeit the ex-istence of the 201TKSERT206 deletion, the VP22 of the CVI988/Rispens vaccine strain has also intercel-lular-trafficking function, which might serve as a potential alternative delivering protein instead of virulent strains VP22. | CHEN HongJun, SONG CuiPing, QIN AiJian & ZHANG ChenFei Key Lab of Jiangsu Preventive Veterinary Medicine, Yangzhou University, Yangzhou 225009, China | 2007 | Science China(Life Sciences)2007，50，1： | 6 |
| 5 | Rainfall-runoff simulation and flood forecasting for Huaihe Basin显示文摘The main purpose of this study was to forecast the inflow to Hongze Lake using the Xin'anjiang rainfall-runoff model.The upper area of Hongze Lake in the Huaihe Basin was divided into 23 sub-basins,including the surface of Hongze Lake.The influence of reservoirs and gates on flood forecasting was considered in a practical and simple way.With a one-day time step,the linear and non-linear Muskingum method was used for channel flood routing,and the least-square regression model was used for real-time correction in flood forecasting.Representative historical data were collected for the model calibration.The hydrological model parameters for each sub-basin were calibrated individually,so the parameters of the Xin'anjiang model were different for different sub-basins.This flood forecasting system was used in the real-time simulation of the large flood in 2005 and the results are satisfactory when compared with measured data from the flood. | Li Zhijia Wang Lili Bao Hongjun Song Yu Yu Zhongbo | 2008 | Water Science and Engineering2008，1，3： | 5 |
| 6 | KEY TECHNOLOGY OF D-INSAR AT X-BAND FOR MONITORING LAND SUBSIDENCE IN MINING AREA AND ITS APPLICATION显示文摘In theory, land subsidence measurement results with high accuracy can be obtained by using the Differential Interferometry Synthetic Aperture Radar(D-InSAR) at X-band. In practice, however, the measuring accuracy of D-InSAR at X-band has been seriously affected by some factors, e.g., decorrelation and high deformation gradient. In this work, the monitoring capability of D-InSAR for coal-mining subsidence is evaluated by using SAR data acquired by TerrraSAR-X system. The SAR image registration method for low coherence image pairs, the denoising phase filter for high noise level interferogram and atmospheric effects mitigation method are the key technical aspects which directly influence the measurement results of D-InSAR at X-band. Thus, a robust image registration method, an improved phase filter method and an atmospheric effects mitigation method are proposed in this paper. The proposed image registration method successfully achieves InSAR coregistration, while the amplitude cross-correlation cannot properly coregister low coherence SAR image pairs. Moreover, the time complexity of the proposed image registration method is obviously slighter than that of the Singular Value Decomposition(SVD) method. The comparing experiment results and the unwrapping phase results show that the improved Goldstein filter is more effective than the original Goldstein filter in noise elimination. The atmospheric influence correction experiment results show that the land subsidence areas with atmospheric influence correction are more clarified than that of without atmospheric influence correction. In summary, the presented methods directly improved the measurement results of D-InSAR at X-band. | Li Xinglin Liu Donglie Song Hongjun Chen Runpu Li Hongyu | 2014 | Journal of Electronics(China)2014，31，5： | 5 |
| 7 | Conjugate heat transfer investigations of turbine vane based on transition models显示文摘The accurate simulation of boundary layer transition process plays a very important role in the prediction of turbine blade temperature field. Based on the Abu-Ghannam and Shaw (AGS) and c-Re h transition models, a 3D conjugate heat transfer solver is developed, where the fluid domain is discretized by multi-block structured grids, and the solid domain is discretized by unstructured grids. At the unmatched fluid/solid interface, the shape function interpolation method is adopted to ensure the conservation of the interfacial heat flux. Then the shear stress transport (SST) model, SST & AGS model and SST & c-Re h model are used to investigate the flow and heat transfer characteristics of Mark II turbine vane. The results indicate that compared with the full turbulence model (SST model), the transition models could improve the prediction accuracy of temperature and heat transfer coefficient at the laminar zone near the blade leading edge. Compared with the AGS transition model, the c-Re h model could predict the transition onset location induced by shock/boundary layer interaction more accurately, and the prediction accuracy of temperature field could be greatly improved. | Zhang Hongjun Zou Zhengping Li Yu Ye Jian Song Songhe | 2013 | Chinese Journal of Aeronautics2013，26，4： | 5 |
| 8 | Non-coding Transcripts from Enhancers:New Insights into Enhancer Activity and Gene Expression Regulation显示文摘Long non-coding RNAs(lncRNAs) have gained widespread interest in the past decade owing to their enormous amount and surprising functions implicated in a variety of biological processes.Some lncRNAs exert function as enhancers,i.e.,activating gene transcription by serving as the cis-regulatory molecules.Furthermore,recent studies have demonstrated that many enhancer elements can be transcribed and produce RNA molecules,which are termed as enhancer RNAs(eRNAs).The e RNAs are not merely the by-product of the enhancer transcription.In fact,many of them directly exert or regulate enhancer activity in gene activation through diverse mechanisms.Here,we provide an overview of enhancer activity,transcription of enhancer itself,characteristics of e RNAs,as well as their roles in regulating enhancer activity and gene expression. | Hongjun Chen Guangshi Du Xu Song Ling Li | 2017 | Genomics, Proteomics & Bioinformatics2017，15，3： | 5 |
| 9 | Decadal characteristics of the floating Ulva and Sargassum in the Subei Shoal,Yellow Sea显示文摘The data of field surveys during 2009 to 2018 was analyzed to understand the seasonality and inter-annual variability of the floating Ulva and Sargassum in the Subei Shoal,the southwestern Yellow Sea of China on decadal scale.The floating Ulva biomass was consistently originated from the central region of the Subei Shoal in middle to late April,increased rapidly,drifted and extended into the offshore water in May and June.The average floating Ulva biomass in the shoal generally increased over the years with evident inter-annual fluctuations.In contrast,pelagic Sargassum was accumulated in the Subei Shoal and formed the spring bloom only in 2013,2017 and 2018,and the biomass was higher than the co-occurring Ulva during the survey in these three years.Compared to the raft-origin floating Ulva,genesis and development of the pelagic Sargassum was distinct.Based on the current research,the Sargassum biomass was exotic and often initiated in the offshore water in March,and intruded into the shoal in April and May.The analysis on the environmental parameters was inconclusive since multiple anthropogenic and non-indigenous factors could influence the green tides in this region.Further research covering both the East China Sea and the Yellow Sea is needed to trace the origin of the floating Sargassum and to understand the interactions between these two co-occurring seaweeds. | Jie Xiao Shiliang Fan Zongling Wang Mingzhu Fu Hongjun Song Xiao Wang Chao Yuan Min Pang Xiaoxiang Miao Xuelei Zhang | 2020 | Acta Oceanologica Sinica2020，39，10： | 4 |
| 10 | Marek's disease virus VP22 enhances potentially the immune response of E SAT-6/CFP-10 against Mycobacterium bovis infection显示文摘对 Mycobacterium bovis 的当前可得到的疫苗,肺结核的原因的代理人,别提供可靠功效,因此对有改进功效的一支新奇疫苗有需要。这里,我们使用蛋白质 transduction 技术交付直接表示 mycobacterial 抗原指向房间的 DNA 疫苗。我们使用了包括 VP22 的领域(PTD ) 蛋白质从 Marek 的疾病病毒 serotype 结合的各种各样的蛋白质 transduction 1 (MDV-1 ) ,作为为编码抗原的 DNA 构造的交货系统,早能分泌的 antigenic target-6 kDa (ESAT-6 ) 蛋白质和文化过滤蛋白质 10 (CFP-10 ) M。bovis。真核细胞的表示 plasmid pZ106,编码抗原 ESAT-6 和 CFP-10,结合了到各种各样的 PTD,被用来构造试验性的准备。我们的调查结果与 CFP-10 独自或在联合表明了那 VP22 : ESAT-6 熔化蛋白质能传播进包围 transfected 房间的房间单层的所有原子核。而激活 trans transcriptional PTD 出现了,熔化蛋白质和 8R 肽的有限交货是不能的交付熔化蛋白质进任何 untransfected 房间。我们证明了有熔化到 VP22 的准备的那免疫导致更高的抗体和干扰素 -- titer (P < 0.05 ) 。一起拿,我们的结果证明 MDV-1 VP22 用 DNA 疫苗在基因治疗和免疫用作潜在的有免疫力的 enhancer,为 M 的预防提供一条新奇途径。bovis 感染。 | Hongjun Chen Wei Wang Cuiping Song Shengqing Yu Chan Ding | 2010 | Acta Biochimica et Biophysica Sinica2010，42，5： | 4 |
| 11 | In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics显示文摘 | Michael A. Bonaguidi Michael A. Wheeler Jason S. Shapiro Ryan P. Stadel Gerald J. Sun Guo-li Ming Hongjun Song | 2011 | Cell2011，，7： | 2 |
| 12 | On the Fourier approximation method for steady water waves显示文摘A computational method for steady water waves is presented on the basis of potential theory in the physical plane with spatial variables as independent quantities. The finite Fourier series are applied to approximating the free surface and potential function. A set of nonlinear algebraic equations for the Fourier coefficients are derived from the free surface kinetic and dynamic boundary conditions. These algebraic equations are numerically solved through Newton's iterative method, and the iterative stability is further improved by a relaxation technology. The integral properties of steady water waves are numerically analyzed, showing that(1) the set-up and the set-down are both non-monotonic quantities with the wave steepness, and(2) the Fourier spectrum of the free surface is broader than that of the potential function. The latter further leads us to explore a modification for the present method by approximating the free surface and potential function through different Fourier series, with the truncation of the former higher than that of the latter. Numerical tests show that this modification is effective, and can notably reduce the errors of the free surface boundary conditions. | ZHAO Hongjun SONG Zhiyao LI Ling KONG Jun | 2014 | Acta Oceanologica Sinica2014，33，5： | 2 |
| 13 | Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction显示文摘 | Longxiang Su Lin Feng Qing Song Hongjun Kang Xingang Zhang Zhixin Liang Yanhong Jia Dan Feng Changting Liu Lixin Xie Celeste C. Finnerty | 2013 | Mediators of Inflammation2013，，： | 2 |
| 14 | On the universal third order Stokes wave solution显示文摘This paper presents a universal third-order Stokes solution with uniform current. This solution is derived on the basis of potential theory by expanding the free surface and potential function in Fourier series and determining the Fourier coefficients by solving a set of nonlinear algebraic equations through the Taylor expansion and perturbation method. The universal solution is expressed upon the still water depth with the still water level as datum and retains a global perturbation parameter. The wave set-up term generated by the self-interaction of oscillatory waves is explicitly included in the free surface function. With the use of different definitions for the wave celerity, different water levels as the datum, different non-dimensional variables as the perturbation parameter, and different treatments for the total head, the universal solution can be reduced to the existing various Stokes solutions, thus explaining the reasons and the physical significance of different non-periodic terms in them, such as the positive or negative constant term in the free surface expression and the time-or space-proportional term in the potential function. | SONG ZhiYao ZHAO HongJun LI Ling Lü GuoNian | 2013 | Science China Earth Sciences2013，56，1： | 2 |
| 15 | Tbr2-expressing intermediate progenitor cells in the adult mouse hippocampus are unipotent neuronal precursors with limited amplification capacity under homeostasis显示文摘神经发生在马头鱼尾的怪兽在二坚持成年哺乳动物的大脑,侧面的室的 subventricular 地区和有牙齿的回转的 subgranular 地区的地点。在成年 subgranular 地区,光线的 gliallike 房间(RGL ) 是能产生星形细胞和神经原的 multipotent 干细胞。在产生神经原的过程, RGL 不均匀地划分产生一 RGL 和一个中间的祖先房间(欧洲电脑生产厂商) 。欧洲电脑生产厂商被认为是放大增殖并且最后产生成熟小粒神经原的房间的运输的一张人口。在同种细胞的水平的单个欧洲电脑生产厂商的性质很好没被理解。而且,欧洲电脑生产厂商是否能产生星形细胞或回复回到 RGL,不是清楚的,除产生神经原以外。这里,我们为同种细胞的分析开发了基因标记策略并且在在用 Tbr2 克里族 T2 老鼠。用这种技术,我们识别了 Tbr2 克里族 T2 作为不在动态平衡下面产生星形细胞或 RGL 的 unipotent neuronal 先锋把欧洲电脑生产厂商标记。另外,我们证明这些标记的欧洲电脑生产厂商很快以一种同步方式产生不成熟的神经原并且不在动态平衡下面经历扩大的重要数量,在受到充实的环境 / 跑的动物,或在有不同年龄的动物。在摘要,我们的学习建议在成年老鼠马头鱼尾的怪兽的表示 Tbr2 欧洲电脑生产厂商是 unipotent 先锋并且没有主要扩大,很快产生不成熟的神经原。 | Daniel A. Berg , Ki-Jun Yoon Brett Will Alex Y. Xiao Nam-Shik Kim Kimberly M. Christian Hongjun Song Guo-li Ming | 2015 | Frontiers in Biology2015，10，3： | 2 |
| 16 | Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions显示文摘 | Guo-li Ming Hongjun Song | 2011 | Neuron2011，，4： | 2 |
| 17 | Optimiza- tion analysis of the staggered herringbone micro-mixerbased on the slip-driven method 显示文摘 | Song Hongjun Yin Xiezhen Bennett Dawn J | 2008 | Chemical Enginee- ring Research and Design2008，86，8： | 1 |
| 18 | Cell-Autonomous Inactivation of the Reelin Pathway Impairs Adult Neurogenesis in the Hippocampus显示文摘 | Catia M. Teixeira Michelle M. Kron Nuria Masachs Helen Zhang Diane C. Lagace Albert Martinez Isabel Reillo Xin Duan Carles Bosch Lluis Pujadas Lucas Brunso Hongjun Song Amelia J. Eisch Victor Borrell Brian W. Howell Jack M. Parent Eduardo Soriano | 2012 | Journal of Neuroscience2012，，35： | 1 |
| 19 | Astroglia induce neurogenesis from adult neural stem cells显示文摘 | Hongjun Song Charles F Stevens Fred H Gage | 2002 | Nature2002，417，： | 1 |
| 20 | Adaptive detection of distributed targets in compound- Gaussian clutter with inverse gamma texture 显示文摘 | SHANG Xiuqin SONG Hongjun WANG Yu | 2012 | Digital Signal Processing2012，22，6： | 1 |
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