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11篇 您的检索式:作者名="Haochen Hu"
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1Review of low timing jitter mode-locked fiber lasers and applications in dual-comb absolute distance measurement显示文摘Passively mode-locked fiber lasers emit femtosecond pulse trains with excellent short-term stability. The quantum-limited timing jitter of a free running femtosecond erbium-doped fiber laser working at room temperature is considerably below one femtosecond at high Fourier frequency. The ultrashort pulse train with ultralow timing jitter enables absolute time-of-flight measurements based on a dual-comb implementation, which is typically composed of a pair of optical frequency combs generated by femtosecond lasers. Dead-zone-free absolute distance measurement with sub-micrometer precision and kHz update rate has been routinely achieved with a dual-comb configuration, which is promising for a number of precision manufacturing applications, from large step-structure measurements prevalent in microelectronic profilometry to three coordinate measurements in large-scale aerospace manufacturing and shipbuilding. In this paper, we first review the sub-femtosecond precision timing jitter characterization methods and approaches for ultralow timing jitter mode-locked fiber laser design. Then, we provide an overview of the state-of-the-art dual-comb absolute ranging technology in terms of working principles, experimental implementations, and measurement precisions. Finally, we discuss the impact of quantum-limited timing jitter on the dual-comb ranging precision at a high update rate. The route to highprecision dual-comb range finder design based on ultralow jitter femtosecond fiber lasers is proposed.Haosen Shi Youjian Song Runmin Li Yuepeng Li Hui Cao Haochen Tian Bowen Liu Lu Chai Minglie Hu 2018Nanotechnology and Precision Engineering2018,1,4:9
2Sodium tungsten bronze(Na_(x)WO_(3))-doped near-infrared-shielding bulk glasses for energy-saving applications显示文摘Tungsten bronze coatings and films have attracted global attention for their applications in near-infrared(NIR)-shielding windows.However,they are unstable in strong ultraviolet,humid heat,alkaline and/or oxidizing environments and are difficult to be coated on glass surfaces with complex shape.Here,we address these limitations by doping sodium tungsten bronze(Na_(x)WO_(3))into bulk glasses using a simple glass melting method.X-ray diffraction,Raman spectroscopy,X-ray photoelectron spectroscopy,TEM and SEM-EDS characterization confirmed the presence of sodium tungsten bronze(Na_(x)WO_(3))functional units inside the 34SiO_(2)-38B_(2)O_(3)-28NaF glass matrix.Because the functional units are well protected by the glass matrix,the fabricated glasses are stable under hot,humid,oxidizing conditions,as well as under ambient conditions,with no change after 360 days.The NIR-shielding performance of these glasses can be adjusted to as high as 100%by varying WO_(x)concentration(2-8 mol%)and quenching temperature(1000-1400℃).With a content of 6 mol%WO_(x)and a quenching temperature of 1000℃,the bulk glass shows 63%transmission of visible light and only 11%transmission of NIR light at 1100 nm.Thermal insulation experiments show that the NIR-shielding performance of the glasses are far superior to commercial soda lime window glass or indium-doped tin oxide(ITO)glass,and comparable to cesium tungsten bronze coated glass.The novel bulk glasses have higher stability,simpler processing,and can be easily made into complex shapes,making them excellent alternative materials for energy-saving glasses.Guang Yang Yunhang Qi Daming Hu Haochen Wang Hongfei Chen Liangmiao Zhang Chuanxiang Cao Bin Liu Fang Xia Yanfeng Gao 2021Journal of Materials Science & Technology2021,,30:3
3Efficacy of rigosertib, a small molecular RAS signaling disrupter for the treatment of KRAS-mutant colorectal cancer显示文摘Objective:Mutant KRAS,the principal isoform of RAS,plays a pivotal role in the oncogenesis of colorectal cancer by constitutively activating the RAF/MEK/ERK and PI3K/AKT pathways.Effective targeted therapies are urgently needed.We investigated whether rigosertib,a benzyl styryl sulfone RAS signaling disruptor,could selectively kill KRAS-mutant colorectal cancer cells.Methods:CCK-8 was used to determine the cell viability.Patient-derived tumor and cancer cell xenograft models were used to detect the inhibitory efficacy of rigosertib.Flow cytometry was used to evaluate the apoptosis and cell cycle progression.Apoptosis and cell cycle arrest markers were detected by Western blot.DCFH-DA was used to determine the reactive oxygen species.Immunohistochemistry staining and Western blot were performed to characterize RAS signaling markers in colorectal cancer tissues and cells.Results:Rigosertib(RGS)exhibited a cytotoxic effect against colorectal cancer cells,which was greater in KRAS-mutant cells.Furthermore,RGS induced mitotic arrest and oxidative stress-dependent apoptosis in KRAS-mutant DLD1 and HCT116 cells.Besides,RGS disrupted RAS signaling,and the inhibition of RAS/MEK/ERK was independent of cellular oxidative stress.Using patient-derived xenograft models,the response and tumor inhibition of RGS were significantly higher in the KRAS-mutant subgroup,while p-MEK,p-ERK,and p-AKT levels of RGS-treated tumors were significantly decreased.Finally,in a KRAS-mutant,chemotherapy-resistant patient-derived xenograft model,RGS showed a stronger therapeutic effect than the combination standard therapy involving fluoropyrimidine+oxaliplatin/irinotecan+bevacizumab.Conclusions:These data showed that targeting RAS signaling using RGS could be a therapeutic treatment for KRAS-mutant colorectal cancer patients.Xinyi Zhou Qian Xiao Dongliang Fu Haochen Zhang Yang Tang Jinjie He Yeting Hu Xiangxing Kong Fei Teng Xiangrui Liu Ying Yuan Kefeng Ding 2022Cancer Biology & Medicine2022,19,2:2
4Caspase‐3 Modulates Regenerative Response After Stroke显示文摘Wenying Fan Yiqin Dai Haochen Xu Ximin Zhu Ping Cai Lixiang Wang Chungang Sun Changlong Hu Ping Zheng Bing‐Qiao Zhao 2014Stem Cells2014,,2:1
5Semi-supervised cardiac MRI image of the left ventricle segmentation algorithm based on contrastive learning显示文摘A semi-supervised convolutional neural network segmentation method of medical images based on contrastive learning is proposed. The cardiac magnetic resonance imaging(MRI) images to be segmented are preprocessed to obtain positive and negative samples by labels. The U-Net shrinks network is applied to extract features of the positive samples, negative samples, and input samples. In addition, an unbalanced contrastive loss function is proposed, which is weighted with the binary cross-entropy loss function to obtain the total loss function. The model is pre-trained with labeled samples, and unlabeled images are predicted by the pre-trained model to generate pseudo-labels. A pseudo-label post-processing algorithm for removing disconnected regions and hole filling of pseudo-labels is proposed to guide the training process of semi-supervised networks. The results on the Sunnybrook dataset show that the segmentation results of this model are better, with a higher dice coefficient, accuracy, and recall rate.ZHU Enrong ZHAO Haochen HU Xiaofei 2022Optoelectronics Letters2022,18,9:0
6Navigation in virtual and real environment using brain computer interface:a progress report显示文摘A brain-computer interface (BCI) facilitates bypassing the peripheral nervous system and directly communicating with surrounding devices. Navigation technology using BCI has developed-from exploring the prototype paradigm in the virtual environment (VE) to accurately completing the locomotion intention of the operator in the form of a powered wheelchair or mobile robot in a real environment. This paper summarizes BCI navigation applications that have been used in both real and VEs in the past 20 years. Horizontal comparisons were conducted between various paradigms applied to BCI and their unique signal-processing methods. Owing to the shift in the control mode from synchronous to asynchronous, the development trend of navigation applications in the VE was also reviewed. The contrast between high level commands and low-level commands is introduced as the main line to review the two major applications of BCI navigation in real environments: mobile robots and unmanned aerial vehicles (UAVs). Finally, applications of BCI navigation to scenarios outside the laboratory;research challenges, including human factors in navigation application interaction design;and the feasibility of hybrid BCI for BCI navigation are discussed in detail.Haochen HU Yue LIU Kang YUE Yongtian WANG 2022Virtual Reality & Intelligent Hardware2022,4,2:0
7Boosted high-temperature electrical characteristics of AlGaN/GaN HEMTs with rationally designed compositionally graded AlGaN back barriers显示文摘Wide bandgap GaN-based HEMTs have shown great potential as key components in various power electronic systems but still face challenges in the pursuit of devices with stable operation capability especially in harsh environments.Here,we report a high-performance double heterojunction(DH)based AlGaN/GaN HEMT by incorporating a decreasing-Al-composition(DAC)graded AlGaN back barrier(BB)beneath the GaN channel.Thanks to the improved electron confinement enabled by graded BB,the DHHEMT exhibits significantly improved on-state drain current density and off-state breakdown voltage compared with a single heterojunction(SH)based HEMT.More intriguingly,with an additional Si Nx passivation layer,the surface states of the DH-HEMTs can be effectively suppressed,leading to an almost constant offstate leakage current and negligible gate contact degradation across the temperature range from 25℃to 150℃.These results highlight the superiority and reliability of the proposed graded AlGaN BB to boost device characteristics for applications under high temperatures and harsh conditions.Haochen ZHANG Yue SUN Kunpeng HU Lei YANG Kun LIANG Zhanyong XING Hu WANG Mingshuo ZHANG Huabin YU Shi FANG Yang KANG Haiding SUN 2023Science China(Information Sciences)2023,66,8:0
8Double-Doped Carbon-Based Electrodes with Nitrogen and Oxygen to Boost the Areal Capacity of Zinc-Bromine Flow Batteries显示文摘Ensuring a stable power output from renewable energy sources,such as wind and solar energy,depends on the development of large-scale and long-duration energy storage devices.Zinc–bromine fl ow batteries(ZBFBs)have emerged as cost-eff ective and high-energy-density solutions,replacing expensive all-vanadium fl ow batteries.However,uneven Zn deposition during charging results in the formation of problematic Zn dendrites,leading to mass transport polarization and self-discharge.Stable Zn plating and stripping are essential for the successful operation of high-areal-capacity ZBFBs.In this study,we successfully synthesized nitrogen and oxygen co-doped functional carbon felt(NOCF4)electrode through the oxidative polymerization of dopamine,followed by calcination under ambient conditions.The NOCF4 electrode eff ectively facilitates effi cient“shuttle deposition”of Zn during charging,signifi cantly enhancing the areal capacity of the electrode.Remarkably,ZBFBs utilizing NOCF4 as the anode material exhibited stable cycling performance for 40 cycles(approximately 240 h)at an areal capacity of 60 mA h/cm^(2).Even at a high areal capacity of 130 mA h/cm^(2),an impressive energy effi ciency of 76.98%was achieved.These fi ndings provide a promising pathway for the development of high-areal-capacity ZBFBs for advanced energy storage systems.Xiaoyun Sun Deren Wang Haochen Hu Xin Wei Lin Meng Zhongshan Ren Sensen Li 2024Transactions of Tianjin University2024,30,1:0
9Observation of polarity-switchable photoconductivity in lInitride/MoS_(x)core-shell nanowires显示文摘Ⅱ-Ⅴsemiconductor nanowires are indispensable building blocks for nanoscale electronic and optoelectronic devices.However,solely relying on their intrinsic physical and material properties sometimes limits device functionalities to meet the increasing demands in versatile and complex electronic world.By leveraging the distinctive nature of the one-dimensional geometry and large surface-to-volume ratio of the nanowires,new properties can be attained through monolithic integration of conventional nanowires with other easy-synthesized functional materials.Herein,we combine high-crystal-quality lInitridle nanowires with amorphous molybdenum sulfides(a-MoS)to construct II.nitride/a-MoS_(x) core-shell nanostructures.Upon light ilumination,such nanostructures exhibit striking spectrally distinctive photodetection characteristic in photoelectrochemical environment,demonstrating a negative photoresponsivity of-100.42 mA W^(-1)under 254 nm ilumination,and a positive photoresponsivity of 29.5 mA W^(-1)under 365 nm ilumination.Density functional theory calculations reveal that the successful surface modifcation of the nanowires via a-MoS_(x)decoration accelerates the reaction process at the electrolyte/nanowire interface,leading to the generation of opposite photocurrent signals under different photon ilumination.Most importantly,such polarity-switchable photoconductivity can be further tuned for multiple wavelength bands photodetection by simply adjusting the surrounding environment and/or tailoring the nanowire composition,showing great promise to build light-wavelength controllable sensing devices in the future.Danhao Wang Wentiao Wu Shi Fang Yang Kang Xiaoning Wang Wei Hu Huabin Yu Haochen Zhang Xin Lu Yuanmin Luo Jr-Hau He Lan Fu Shibing Long Sheng Liu Haiding Sun 2022Light(Science & Applications)2022,11,11:0
10Improvement of Ga_(2)O_(3)vertical Schottky barrier diode by constructing NiO/Ga_(2)O_(3)heterojunction显示文摘The high critical electric field strength of Ga_(2)O_(3)enables higher operating voltages and reduced switching losses in power electronic devices.Suitable Schottky metals and epitaxial films are essential for further enhancing device performance.In this work,the fabrication of vertical Ga_(2)O_(3)barrier diodes with three different barrier metals was carried out on an n--Ga_(2)O_(3)homogeneous epitaxial film deposited on an n+-β-Ga_(2)O_(3)substrate by metal-organic chemical vapor deposition,excluding the use of edge terminals.The ideal factor,barrier height,specific on-resistance,and breakdown voltage characteristics of all devices were investigated at room temperature.In addition,the vertical Ga_(2)O_(3)barrier diodes achieve a higher breakdown volt-age and exhibit a reverse leakage as low as 4.82×10^(-8)A/cm^(2)by constructing a NiO/Ga_(2)O_(3)heterojunction.Therefore,Ga_(2)O_(3)power detailed investigations into Schottky barrier metal and NiO/Ga_(2)O_(3)heterojunction of Ga_(2)O_(3)homogeneous epitaxial films are of great research potential in high-efficiency,high-power,and high-reliability applications.Xueqiang Ji Jinjin Wang Song Qi Yijie Liang Shengrun Hu Haochen Zheng Sai Zhang Jianying Yue Xiaohui Qi Shan Li Zeng Liu Lei Shu Weihua Tang Peigang Li 2024Journal of Semiconductors2024,45,4:0
11Physical processes determining the distribution patterns of Nemopilema nomurai in the East China Sea显示文摘The giant jellyfish Nemopilema nomurai is the largest and most dangerous jellyfish species in East Asian waters,and the N.nomurai bloom causes serious problem in coastal industries,fisheries,and tourism.In the previous surveys,we found N.nomurai could not be observed in the south of 30°N.In this paper,we analyzed the mechanism of this phenomenon.After exploring the possible impacts of different environmental factors,we found that physical processes are essential to the distribution pattern of N.nomurai rather than biological or chemical factors in the East China Sea.The combination of the location of the initial breeding places of N.nomurai and the current system determine the distribution pattern.This study could provide important insights to the potential control of the giant jellyfish in the Chinese coastal waters.Song SUN Haochen XIAN Ziyuan HU Xiaoxia SUN Fang ZHANG 2023Journal of Oceanology and Limnology2023,41,6:0
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