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| 1 | Endoscopic pancreatic sphincterotomy:indications,outcome,and a safe stentless technique显示文摘Endoscopicpancreaticsphincterotomy:indications,outcome,andasafestentlesstechniquericElton,MD,DouglasA.Howel,MD,WilisG.Parsons... | Eric Elton, MD, Douglas A. Howell, MD, Willis G. Parsons, MD, Tahir Qaseem, MD, Brian L. Hanson, MDPortland, MaineDivision of Gastroenterology, Maine Medical Center, Portland, Maine | 1998 | World Journal of Gastroenterology1998，4，3： | 16 |
| 2 | 激光诊断技术在脉冲爆震发动机研究中的应用显示文摘在美国海军研究生院及斯坦福大学的脉冲爆震发动机 (PDE)模型上 ,应用两种新发展的二极管激光诊断技术———光吸收 /高温辐射组合测定法和多路复合可调二极管激光 (TDL)技术 ,测量了其中的温度、各燃烧产物组分等重要参数 ,并与传统方法所得结果进行对比 ,说明新方法可靠、准确 ,适合爆震燃烧流场这种特殊环境 ,测量精度更高 ,而且更加简便。 | 范玮 Jenkins TP Sanders ST Hanson RK | 2001 | 推进技术2001，22，4： | 10 |
| 3 | 提高中国社会医疗保障制度的经济保护,实现全民健康覆盖显示文摘中国基本实现了医疗保险全民覆盖,极大地促进了医疗卫生服务的获得和使用。对于贫困人口的经济保护仍然需要加强,因为他们更有可能发生灾难性卫生支出。如果不能提高医疗卫生体系的效率,加强初级卫生保健和改革供方支付制度,增加医疗卫生投入对促进经济保护的作用也是有限的。 | 方海(译) Karen Eggleston Kara Hanson 吴明 | 2019 | 英国医学杂志中文版2019，22，12： | 7 |
| 4 | 左心室的总能量和能量效率的临床价值显示文摘报告用物理学基本概念,对60例不同心脏病人的左心室的总能量、搏出功及压力-容积环进行分析。结果表明,心脏是个节能型器官,正常心室的总能量较低,能量效率最高;血流动力学异常时心脏代偿的结果是总能量增加,而维持搏出功相对稳定,这种代偿是以消耗能量贮备为代价的。认为SWJ能反映搏出功,TEI和EE是定量评价心脏贮备能力的客观指标。压力-容积环的位移和变形可以非常直观而准确地反映出这些指标。这些对于评价亚临床期患者的心功能极有意义。 | 魏大愚 LopezJF HansonS | 1992 | 临床心血管病杂志1992，8，1： | 7 |
| 5 | Sewage pollution in Negril, Jamaica: effects on nutrition and ecology of coral reef macroalgae显示文摘Coral reefs in the Negril Marine Park (NMP), Jamaica, have been increasingly impacted by nutrient pollution and macroalgal blooms following decades of intensive development as a major tourist destination. A baseline survey of DIN and SRP concentrations, C:N:P and stable nitrogen isotope ratios (δ15N) of abundant reef macroalgae on shallow and deep reefs of the NMP in 1998 showed strong P-limitation and evidence of increasing sewage pollution. In 1999, a sewage collection and treatment project began diverting wastewater from the resort and urban areas to a pond system that discharged partially-treated effluent into the South Negril River (SNR). These sewage discharges significantly increased concentrations of NH4+ and SRP (N:P ~13) in the SNR, which flows into Long Bay and around Negril’s 'West End'. Concentrations of SRP, the primary limiting nutrient, were higher on shallow reefs of the West End in 2001 compared to 1998. Stable nitrogen isotope ratios (δ15N) of abundant reef macroalgae on both shallow and deep reefs of the West End in 2002 were significantly higher than baseline values in 1998, indicating an escalating impact of sewage nitrogen pollution over this timeframe. The increased nutrient concentrations and δ15N enrichment of reef macroalgae correlated with blooms of the chlorophyte Chaetomorpha linum in shallow waters of Long Bay and Codium isthmocladum and Caulerpa cupressoides on deep reefs of the West End. Sewage treatment systems adjacent to coral reefs must include nutrient removal to ensure that DIN and SRP concentrations, after dilution, are below the low thresholds noted for these oligotrophic ecosystems. | B. E. LAPOINTE K. THACKER C. HANSON L. GETTEN | 2011 | Chinese Journal of Oceanology and Limnology2011，29，4： | 5 |
| 6 | A Myosin XI Tail Domain Homologous to the Yeast Myosin Vacuole-Binding Domain Interacts with Plastids and Stromules in Nicotiana benthamiana显示文摘肌动朊细胞骨架在植物房间在许多不同细胞器的活动性起一个作用,包括叶绿体,线粒体, Golgi,和 peroxisomes。当进步在识别涉及肌浆球蛋白 XI 的不同成员动员的货物的各种各样的植物细胞器,不是所有的 trafficking 的肌浆球蛋白马达被取得了时,家庭还有识别。在叶绿体放和 mitochondrial 运动的肌浆球蛋白的参与被导致病毒的基因 silencing (VIGS ) 的表示表明在烟草的构造。当有从一台肌浆球蛋白 XI 马达的二个不同保存序列的 VIGS 与标记 GFP 的质体或线粒体在工厂被执行时,叶绿体在黑暗中放是反常的,并且 mitochondrial 运动停止了。因为这些和优先的观察含有为在质体和 stromule 运动的肌浆球蛋白和肌动朊细胞骨架的一个角色,我们寻找了能与质体和 stromules 联系的肌浆球蛋白尾巴领域。当时黄荧光灯有肌浆球蛋白 XI-F 的全部尾巴区域的蛋白质(YFP ) 熔化通常仅仅在细胞质被发现,我们观察到 Arabidopsis 或 Nicotiana benthamiana YFP::myosin XI-F 跟踪对在 N 在短暂表示以后与质体和 stromules 联系的酵母 myo2p 液泡绑定领域相应的领域。benthamiana。一起拿,这些观察含有在质体和 stromules 的动力学的肌浆球蛋白马达蛋白质。 | Amir Sattarzadeh Johanna Krahmer Arnaud D. Germain Maureen R. Hanson | 2009 | Molecular Plant2009，2，6： | 5 |
| 7 | Developmental and Feedforward Control of the Expression of Folate Biosynthesis Genes in Tomato Fruit显示文摘很少植物怎么调整他们的叶酸的内容被知道,包括叶酸的生合成基因的表达式是否在开发期间被安排或由叶酸的层次调制了。也很不叶酸的层次怎么影响另外的基因的表示被知道。这些点用为高叶酸的内容设计的野类型的西红柿水果和水果被探讨。在野类型的水果,在叶酸的生合成指定早步的基因的表示在开发而是另外的基因的期间衰退了。在设计水果 overexpressing 外国 GTP cyclohydrolase 我和 aminodeoxychorismate synthase 基因,各自的内长的基因的表示没变化,但是三下游的小径 genesaminodeoxychorismate lyase , dihydroneopterin aldolase ,和 mitochondrial folylpolyglutamate 的 synthaserespectively 增加了由直到7.8-,2.8-,和1.7褶层,显然响应特定的叶酸的小径代谢物的逐渐增加。这些结果显示在水果,某些叶酸的小径基因发展地被调整并且某些其它由小径中介服从于前馈控制控制。Microarray 分析显示出那仅仅 14 个另外的抄本(11 ? 000 调查了) 在丰富增加了由双重或更在里面高度叶酸的水果,证明叶酸的小径基因的正式就职是相对特定的。 | Jeffrey C. Wallera Tariq A. Akhtar Aurora Lara-Nunez Jesse F. Gregory lli Ryan R McQuinn James J. Giovannoni Andrew D. Hanson | 2010 | Molecular Plant2010，3，1： | 5 |
| 8 | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells显示文摘 | Hsu, TL Hanson, SR Kishikawa, K Wang, SK Sawa, M Wong, CH | 2007 | 中国生物学文摘2007，21，10： | 5 |
| 9 | Cementomimetics——constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides显示文摘Cementum is the outer-,mineralized-tissue covering the tooth root and an essential part of the system of periodontal tissue that anchors the tooth to the bone. Periodontal disease results from the destructive behavior of the host elicited by an infectious biofilm adhering to the tooth root and left untreated,may lead to tooth loss. We describe a novel protocol for identifying peptide sequences from native proteins with the potential to repair damaged dental tissues by controlling hydroxyapatite biomineralization. Using amelogenin as a case study and a bioinformatics scoring matrix,we identified regions within amelogenin that are shared with a set of hydroxyapatite-binding peptides (HABPs) previously selected by phage display. One 22-amino acid long peptide regions referred to as amelogenin-derived peptide 5 (ADP5) was shown to facilitate cell-free formation of a cementum-like hydroxyapatite mineral layer on demineralized human root dentin that,in turn,supported attachment of periodontal ligament cells in vitro. Our findings have several implications in peptide-assisted mineral formation that mimic biomineralization. By further elaborating the mechanism for protein control over the biomineral formed,we afford new insights into the evolution of protein-mineral interactions. By exploiting small peptide domains of native proteins,our understanding of structure-function relationships of biomineralizing proteins can be extended and these peptides can be utilized to engineer mineral formation. Finally,the cementomimetic layer formed by ADP5 has the potential clinical application to repair diseased root surfaces so as to promote the regeneration of periodontal tissues and thereby reduce the morbidity associated with tooth loss. | Mustafa Gungormus Ersin E Oren Jeremy A Horst Hanson Fong Marketa Hnilova Martha J Somerman Malcolm L Snead Ram Samudrala Candan Tamerler Mehmet Sarikaya | 2012 | International Journal of Oral Science2012，4，2： | 5 |
| 10 | A multi-center, double-blind, randomized, parallel group study to evaluate the effects of two different doses of losartan on morbidity and mortality in Chinese patients with symptomatic heart failure intolerant of angiotensin converting enzyme inhibitor treatment显示文摘 | HU Da-yi HUANG Jun CAI Nai-sheng ZHU Wen-ling LI Yi-shi Rachid Massaad Mary E. Hanson Kenneth Dickstein | 2012 | Chinese Medical Journal2012，，21： | 4 |
| 11 | Separating root and soil microbial contributions to soil respiration: A review of methods and observations显示文摘 | P.J. Hanson N.T. Edwards C.T. Garten J.A. Andrews | 2000 | Biogeochemistry2000，，1： | 4 |
| 12 | Global sustainability: Toward definition显示文摘 | Becky J. Brown Mark E. Hanson Diana M. Liverman Robert W. Merideth | 1987 | Environmental Management1987，，6： | 3 |
| 13 | Sib-pair linkage an alysis for susceptibility genes for microvascular complications among Pima India ns with type 2 diabetes显示文摘 | Imperatore G Hanson R L Pettitt D J | | 0，，： | 3 |
| 14 | Market potential, increasing returns and geographic concentration显示文摘 | Gordon H. Hanson | 2004 | Journal of International Economics2004，，1： | 3 |
| 15 | Paleozoic oil–source rock correlations in the Tarim basin, NW China显示文摘 | S.C Zhang A.D Hanson J.M Moldowan S.A Graham D.G Liang E Chang F Fago | 2000 | Organic Geochemistry2000，，： | 3 |
| 16 | Managerial ownership, board structure, and the division of gains in divestitures显示文摘 | Robert C Hanson Moon H Song | 2000 | Journal of Corporate Finance2000，，1： | 3 |
| 17 | Separating root and soil microbial contributions to soil respiration: A review of methods and observations显示文摘 | P.J. Hanson N.T. Edwards C.T. Garten J.A. Andrews | 2000 | Biogeochemistry2000，，1： | 3 |
| 18 | 颗粒溶素肽对白念珠菌的毒性作用显示文摘目的:研究颗粒溶素肽对白念珠菌的毒性作用。方法:将白念珠菌和不同浓度的颗粒溶素肽混合培养后,计算沙氏琼脂培养基平板上白念珠菌菌落数。采用标准微量稀释法测定颗粒溶素肽以及氟康唑(FCZ)对白念珠菌的最低抑菌浓度(MIC)。结果:当相应于颗粒溶素第2和第3个螺旋的肽段G2和G3浓度达到20μg/ml时,对白念珠菌产生较强的细胞毒性,形成的平均菌落数分别从883、937降到203、218,而G1、G4、G5肽段浓度达到40μg/ml时,也不能明显减少白念珠菌平均菌落数。3株标准白念珠菌株对颗粒溶素肽均较为敏感,MIC分别为26、22、29μg/ml,而对FCZ的MIC分别为4、20、128μg/ml。结论:颗粒溶素肽对白念珠菌具有细胞毒性,是人体内天然存在的抗真菌感染物质之一,具有潜在的药物开发意义。 | 陈孙孝 温海 邓安梅 TAO Shiying ZHENG Hanson | 2006 | 第二军医大学学报2006，27，2： | 3 |
| 19 | Evaluating the quality of feed fats and oils and their effects on pig growth performance显示文摘Feed fats and oils provide significant amounts of energy to swine diets, but there is large variation in composition,quality, feeding value, and price among sources. Common measures of lipid quality include moisture, insolubles,and unsaponifiables(MIU), titer, and free fatty acid content, but provide limited information regarding their feeding value. Lipid peroxidation is an important quality factor related to animal growth performance and health, but maximum tolerable limits in various lipids have not been established. Several indicative assays can be used to detect the presence of various peroxidation compounds, but due to the complexity and numerous compounds produced and degraded during peroxidation process, no single method can adequately determine the extent of peroxidation. Until further information is available, using a combination of peroxide value, thiobarbituric acid reactive substances(TBARS), and anisidine value appear to provide a reasonable assessment of the extent of peroxidation in a lipid at a reasonable cost. However, fatty acid composition of the lipid being evaluated should be considered when selecting specific assays. Predictive tests can also be used to estimate the stability or susceptibility of lipids to peroxidation and include active oxygen method, oil stability index, and oxygen bomb method. A review of 16 published studies with pigs has shown an average decrease of 11.4% in growth rate, 8.8% feed intake fed isocaloric diets containing peroxidized lipids compared to diets containing unperoxidized lipids of the same source.Furthermore, serum vitamin E content was generally reduced and serum TBARS content was increased when peroxidized lipids were fed in these studies, suggesting that feeding peroxidized lipids negatively affects metabolic oxidative status of pigs. However, it is unclear if antioxidants are useful additions to lipids to maintain optimal nutritional value, or if their addition to swine diets is beneficial in overcoming a metabolic oxidative challenge. | Gerald C Shurson Brian J Kerr Andrea R Hanson | 2016 | Journal of Animal Science and Biotechnology2016，7，3： | 3 |
| 20 | Endoscopic and Medical Therapy for Chronic Radiation Proctopathy: A Systematic Review显示文摘 | Brian Hanson Roderick MacDonald Aasma Shaukat | 2012 | Diseases of the Colon & Rectum2012，，： | 2 |
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