|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 减少急性冠状动脉综合征和卒中患者求医的延误——美国心脏协会心血管护理委员会和卒中委员会的科学声明显示文摘在寻求急性冠状动脉综合征和卒中症状的治疗方面,患者延误是限制提供这些疾病的确定性治疗的主要因素。尽管数十年来的研究和公众教育活动一直旨在缩短患者延误时间,但大多数患者仍然不能及时求医。在本科学声明中,我们总结了以下证据:(1)证明早期治疗的益处;(2)描述患者延误问题的程度;(3)确定与患者延误及时求医有关的因素;(4)揭示当前减少患者延误措施的不足。最后,提出临床实践和今后研究的建议。 | Debra K. Moser Laura P. Kimble Mark J. Alberts Angelo Alonzo Janet B. Croft Kathleen Dracup Kelly R. Evenson Alan S. Go Mary M. Hand Rashmi U. Kothari George A. Mensah Dexter L. Morris Arthur M. Pancioli Barbara Riegel Julie Johnson Zerwic 李宏建 曲东锋 | 2006 | 国际脑血管病杂志2006，14，10： | 39 |
| 2 | On ultrahigh temperature crustal metamorphism:Phase equilibria,trace element thermometry,bulk composition,heat sources,timescales and tectonic settings显示文摘Ultrahigh temperature(UHT) metamorphism is the most thermally extreme form of regional crustal metamorphism,with temperatures exceeding 900℃.UHT crustal metamorphism is recognised in more than 50 localities globally in the metaniorphic rock record and is accepted as 'normal' in the spectrum of regional crustal processes.UHT metamorphism is typically identified on the basis of diagnostic mineral assemblages such as sapphirine+ quartz,orthopyroxene + sillimanite ± quartz and osumilite in Mg-AIrich rock compositions,now usually coupled with pseudosection-based thermobarometry using internally-consistent thermodynamic data sets and/or Al-in-Orthopyroxene and ternary feldspar thermobarometry.Significant progress in the understanding of regional UHT metamorphism in recent years includes:(1) development of a ferric iron activity-composition thermodynamic model for sapphirine,allowing phase diagram calculations for oxidised rock compositions:(2) quantification of UHT conditions via trace element thermometry,with Zr-in-rutile more commonly recording higher temperatures than Ti-in-zircon.Rutile is likely to be stable at peak UHT conditions whereas zircon may only grow as UHT rocks are cooling.In addition,the extent to which Zr diffuses out of rutile is controlled by chemical communication with zircon;(3) more fully recognising and utilising temperature-dependent thermal properties of the crust,and the possible range of heat sources causing metamorphism in geodynamic modelling studies:(4) recognising that crust partially melted either in a previous event or earlier in a long-duration event has greater capacity than fertile,unmelted crust to achieve UHT conditions due to the heat energy consumed by partial melting reactions:(5) more strongly linking U-Pb geochronological data from zircon and monazite to P-T points or path segments through using Y + REE partitioning between accessory and major phases,as well as phase diagrams incorporating Zr and REE;and(6)improved insight into the settings and factors responsible for UHT metamorphism via geodynamic forward models.These models suggest that regional UHT metamorphism is,principally,geodynamically related to subduction,coupled with elevated crustal radiogenic heat generation rates. | David E.Kelsey Martin Hand | 2015 | Geoscience Frontiers2015，6，3： | 28 |
| 3 | Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques显示文摘Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate,creatinine,2-oxoglutarate(2-OG) ,citrate,taurine,trimethylamine-N-oxide(TMAO) ,succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi defi-ciency and blood stasis syndrome. | LI Lin WANG JianNong REN JianXun XIANG JunFeng TANG YaLin LIU JianXun HANDing | 2007 | Chinese Science Bulletin2007，52，22： | 21 |
| 4 | 钼酸盐在硼硅酸盐玻璃体系中的溶解显示文摘在英国和法国的很多高放核废料中都含有大量的钼。钼在核废料玻璃中的溶解度很低,过量的钼会导致玻璃产生钼酸盐分相从而影响核废料玻璃化的效率和安全。主要研究了钼酸盐在硼酸盐玻璃中的溶解度与玻璃中碱土金属元素的关系以及钼酸盐的溶解对玻璃的结构和性质的影响。在其它玻璃组分不变的情况下,对玻璃中的碱土金属(由镁至钡)进行等摩尔量替换。结果发现,当碱土金属为钙时钼酸盐的溶解度最高,为2.84 mol%。XRD结果显示除了明显分相的玻璃外其它均一玻璃均为无定形态。SEM结果显示玻璃基体内的分相大多为球状/水滴状并呈随机分布;其尺寸与钼酸盐的过量程度有关,但直径都小于1?m。对钙硼硅酸盐玻璃中析出相的EDX分析表明其中富含钼和钙,而TEM结果证明这些析出相为晶体相且符合钼酸钙的电子衍射特征。含钼玻璃有两个强烈的拉曼峰(分别位于320和910 cm–1附近):其强度随玻璃中钼含量的增加而增加,其位置随玻璃中碱土金属元素的变化而偏移。此外,钼的加入也会导致玻璃的玻璃转变温度降低以及玻璃密度增加。 | 谭盛恒 Russell J HAND | 2016 | 中国材料进展2016，35，7： | 12 |
| 5 | Risk factors and clinical responses of pneumonia patients with colistin-resistant Acinetobacter baumannii-calcoaceticus显示文摘BACKGROUND Nosocomial infections with carbapenem-resistant Acinetobacter baumanniicalcoaceticus complex(ABC)strains are great problem for intensive care units.ABC strains can develop resistance to all the antibiotics available.Carbapenem resistance is common and colistin resistance is rare in our country.Knowing the risk factors for colistin resistance is important since colistin seems to be the only remaining therapeutic option for the patients with pneumonia due to extensively drug resistant ABC for our country.AIM To investigate the comparison of clinical responses and outcomes between pneumonia patients with colistin-susceptible and-resistant Acinetobacter sp.Strains.METHODS During the study period,108 patients with pneumonia due to colistin-susceptible strains and 16 patients with colistin-resistant strains were included retrospectively.Continuous variables were compared with the Mann-Whitney U test,and categorical variables were compared using Pearson’s chi-square test or Fisher’s Exact chi-square test for two groups.A binary logistic regression model was developed to identify the potential independent factors associated with colistin resistance in patients with colistin-resistant strains.RESULTS High Acute Physiology and Chronic Health Evaluation II scores(OR=1.9,95%CI:1.4-2.7;P<0.001)and prior receipt of teicoplanin(OR=8.1,95%CI:1.0-63.3;P=0.045)were found to be independent risk factors for infection with colistin-resistant Acinetobacter sp.Different combinations of antibiotics including colistin,meropenem,ampicillin/sulbactam,amikacin and trimethoprim/sulfamethoxazole were used for the treatment of patients with colistin-resistant strains.Although the median duration of microbiological cure(P<0.001)was longer in the colistin-resistant group,clinical(P=0.703),laboratory(P=0.277),radiological(P=0.551),microbiological response(P=1.000)and infection related mortality rates(P=0.603)did not differ between the two groups.Among the patients with infections due to colistin-resistant strains,seven were treated with antibiotic combinations that included sulbactam.Clinical(6/7)and microbiological(5/7)response rates were quite high in these patients.CONCLUSION The optimal therapy regimen is unclear for colistin-resistant Acinetobacter sp.infections.Although combinations with sulbactam seems to be more effective in our study patients,data supporting the usefulness of combinations with sulbactam is very limited. | Hande Aydemir Hande Idil Tuz Nihal Piskin Guven Celebi Canan Kulah Furuzan Kokturk | 2019 | World Journal of Clinical Cases2019，7，10： | 7 |
| 6 | Xen and the art of virtualization显示文摘 | Paul Barham Boris Dragovic Keir Fraser Steven Hand Tim Harris Alex Ho Rolf Neugebauer Ian Pratt Andrew Warfield | 2003 | ACM SIGOPS Operating Systems Review2003，，5： | 6 |
| 7 | Incidence of toxoplasmosis in patients with cirrhosis显示文摘AIM:It is known that toxoplasmosis rarely leads to various liver pathologies,most common of which is granulomatose hepatitis in patients having normal immune systems. Patients who have cirrhosis of the liver are subject to a variety of cellular as well as humoral immunity disorders. Therefore, it may be considered that toxoplasmosis can cause more frequent and more severe diseases in patients with cirrhosis and is capable of changing the course of the disease.The aim of this study was to investigate the frequency of toxoplasmosis in patients with cirrhosis.METHODS:Serum samples were taken from 108 patients with cirrhosis under observation in the Hepatology Polyclinic of the Gastroenterology Clinic,and a control group made up of 50 healthy blood donors. IFAT and ELISA methods were used to investigate the IgG and IgM antibodies, which had developed from these sera.RESULTS:Toxoplasma IgG and IgM antibody positivity was found in 74 (68.5%) of the 108 cirrhotic patients and 24 (48%) of the 50 people in the control group. The difference between them was significant (P<0.05).CONCLUSION: In conclusion, it was found that the toxoplasma sero-prevalence in the cirrhotic patients in this study was higher. Cirrhotic patients are likely to form a toxoplasma risk group. More detailed studies are needed on this subject. | Sebnem Ustun Umit Aksoy Hande Dagci Galip Ersoz | 2004 | World Journal of Gastroenterology2004，10，3： | 6 |
| 8 | 1型糖尿病视网膜病变患者血清唾液酸浓度的增加(英文)显示文摘目的:探讨血清唾液酸和糖尿病性视网膜病变几个阶段之间潜在的关联。方法:1型糖尿病视网膜不同程度病变组40例。对照组30例,对其血清唾液酸水平进行研究。结果:结果显示,研究组与对照组相比有较高的血清唾液酸浓度(95.95±9.5 vs 45.05±19.91mmoL/L,P=0.0001)。我们也观察到糖尿病性视网膜病变的水平逐步上升,其浓度升高(P<0.05),但相关性较弱。血清唾液酸浓度与血糖浓度呈正相关(r=0.67,P=0.0001)。结论:血清唾液酸浓度的增加与视网膜病变阶段有关。这对确定1型糖尿病患者视网膜病变的程度有帮助。但是,仍然需要更详细的研究,以得到更精确的结论。 | Muhsin Eraslan 0zlem Yenice Haluk Kazokoglu Dilek Goga Yavuz Eren Cerman Hande Celiker | 2013 | 国际眼科杂志2013，13，10： | 5 |
| 9 | A Critical Review of the IELTS Writing Test显示文摘 | Hacer Hande Uysal | 2010 | 英语考试研究2010，，11： | 5 |
| 10 | Late clinical characteristics of infants with retinopathy of prematurity and treated with cryotherapy显示文摘AIM: To describe the clinical characteristics and late results of patients with retinopathy of prematurity(ROP)treated with '6h cryotherapy'.·METHODS: Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from1997 to 2005 were recalled to our clinic. Among these 23 patients were available and 46 eyes of 23 infants were included to evaluate for visual acuity, refractive error,ocular alignment, nystagmus, retinal examination(abnormal branching of retinal vessels, retinal thinning,latis degenerations, tortuosity of vessels, straightening of temporal vessels, narrowing of the angle of vessel in the juxtapapillary entrance, pigment changes, macular heterotopia), optic atrophy and optic disc cupping, axial length at birth and axial length at 1y.·RESULTS: The median age at examination was 7(5-18)y.In 32.6% of patients, the visual acuity was ≤20/200 and the mean best corrected visual acuity was 20/35 as measured with a Snellen chart. Mean spherical refractive error was-1.76±2.69 D. The degree of myopia at the last examination was found to be correlated with the elongation of the eye in the first year of life. Exotropia was present in 17.4%(n =8) of infants and esotropia in13%(n =6). The most common retinal abnormality was abnormal branching of retinal vessels(82.6%) followed by retinal thinning(52.2%).·CONCLUSION: The late clinical outcomes of infants with ROP treated in our clinic with cryotherapy seems to comparable with results of laser treatment. | Eren Cerman Deniz Ozarslan Ozcan Hande Celiker Muhsin Eraslan Ozlem Sahin Haluk Kazokoglu | 2016 | International Journal of Ophthalmology(English edition)2016，9，4： | 4 |
| 11 | 回到未来,战略性设计管理:彼时与现在显示文摘1965年,英国领先的设计顾问Michael Farr提出了这样一个问题“如今,我们为何需要设计管理?”,这可以说提供了设计管理的第一个正式的、作为关键性商业规则的定义。从那时起,设计管理便一直处于不断发展和完善的坚定旅程中,行走于设计理论和实践这两个相互关联的领域之间。作为一个有意识的活动领域,设计管理仍处于起步阶段。因此,再次提出Farr在50多年前提出的紧迫问题,既适时及时又至关重要的。 | David Hands | 2018 | 工业设计2018，，2： | 3 |
| 12 | DEVELOPMENT OF SOIL EROSION INDEX MODEL IN TAIWAN WATERSHEDS显示文摘With steep terrain and excessive rainfall, Taiwan is affected by severe soil erosion caused by summer typhoons and storms that bring intensive rainfall and rapid flows,. However, the actual erosion is much less than the value predicted by the USLE because the soil erosion types in Taiwan are different from those in America which has mild slope and dry weather. Developing a soil erosion index model applicable to Taiwan is the important goal of this research. Five factors, namely, soil texture, rainfall type, slope steepness, ground cover and land use, are included in this model. Soil index factor is measured by Km from the USLE model, and other index factors are calculated from local field data. The soil erosion index model (SEIM) is as follows: SE=6x10-7AIfor AI≤50 SE = 0.233AI1.8 for AI > 50 where AI is the total index value, and SE is the soil erosion quantity (ton/ha/yr). After being properly calibrated and verified, SEIM proves to be useful in planning soil and water conservation, and assessing soil erosion impacts in Taiwan. | Su-Chin CHEN, Seasir CHIEN and Cheng-Daw HSIEH Professor, Department of Soil and Water Conservation National Chung-Hsing University, Taichung, 402 Taiwan, China Engineer, Water Way Section, Hand County Government, 260 Taiwan, China Doctoral Student, Ins | 2001 | International Journal of Sediment Research2001，16，1： | 3 |
| 13 | Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease显示文摘 | Adam M Zahm Meena Thayu Nicholas J Hand Amber Horner Mary B Leonard Joshua R Friedman | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，1： | 3 |
| 14 | Prevalence of amebiasis in inflammatory bowel disease in Turkey显示文摘AIM: To explore the prevalence of amebiasis in inflammatory bowel disease (IBD) in Turkey.METHODS: In this study, amoeba prevalence in 160 cases of IBD, 130 of ulcerative colitis and 30 of Crohn′s disease were investigated in fresh faeces by means of wet mount+Lugol′s iodine staining, modified formol ethyl acetate and trichrome staining methods and to compare the diagnostic accuracy of wet mount+Lugol′s iodine staining,modified formol ethyl acetate and trichrome staining methods in the diagnosis of Entamoeba histolytica (E. histolytica)/Entamoeba dispar (E. dispar).RESULTS: E. histolytica/E. dispar cysts and trophozoites were found in 14 (8.75 %) of a total of 160 cases, 13 (10.0 %)of the 130 patients with ulcerative colitis and 1 (3.3 %) of the 30 patients with Crohn′s disease. As for the 105 patients in the control group who had not any gastrointestinal complaints, 2 (1.90 %) patients were found to have E.histolytica/E. dispar cysts in their faeces. Parasite prevalence in the patient group was determined to be significantly higher than that in the control group (Fischer′s Exact Test, P<0.05).When the three methods of determining parasites were compared with one another, the most effective one was found to be trichrome staining method (Kruskal-Wallis Test, P<0.01).CONCLUSION: Consequently, amoeba infections in IBD cases have a greater prevalence compared to the normal population. The trichrome staining method is more effective for the detection of E. histolytica/E. dispar than the wet mount+Lugol′s iodine staining, modified formol ethyl acetate methods. | Sebnem Ustun Hande Dagci Umit Aksoy Yuksel Guruz Galip Ersoz | 2003 | World Journal of Gastroenterology2003，9，8： | 3 |
| 15 | Comparison of long-term results of trabeculectomy to treat pseudoexfoliative glaucoma and primary open angle glaucoma显示文摘AIM: To compare the long term outcome of trabeculectomy in patients with pseudoexfoliative glaucoma(PEG) and primary open angle glaucoma(POAG) in terms of surgical success. METHODS: The success of the trabeculectomy was evaluated by three criteria. Criterion A: intraocular pressure(IOP) ≤21 mm Hg and decrease in IOP ≥20%; Criterion B: IOP ≤18 mm Hg and decrease in IOP ≥30%; Criterion C: IOP ≤15 mm Hg and decrease in IOP ≥50%. Patients that met these criteria without medical treatment were considered to be completely successful, while those that met these criteria with medical treatment were considered partially successful. Significance levels of differences between the POAG and PEG groups in the Kaplan-Meier survival curves were calculated with the log-rank test. RESULTS: Sixty-four eyes from 64 patients with PEG and 51 eyes from 51 patients with POAG were evaluated. No significant differences were detected between the PEG and POAG groups according to full or partial success relative to each of the three criteria(A: P=0.73, 0.32; B: P=0.73, 0.31; C:P=0.90, 0.27). CONCLUSION: There is no difference in the long-term success of trabeculectomy between PEG and POAG patients whose clinical characteristics are otherwise the same. | Vuslat Pelitli Gürlü Hande Gürlü Altan Ozal Omer Benian Levent Alimgil | 2018 | International Journal of Ophthalmology(English edition)2018，11，1： | 3 |
| 16 | The dynamic responses of lamellar and equiaxed nearβ-Ti alloys subjected to multi-pass cross rolling显示文摘This work gives a comparison on the microstructural characteristics,textural discrepancies,and twinning behaviors of lamellar and equiaxed nearβ-Ti alloys during multi-pass cross rolling with a rolling reduction of 20%,50%and 80%.The results showed that the restoration mechanism of the alloy inβphase is strongly dependent on theαmorphologies,and in comparison,strain path has weaker influences on the grain refinement of theβmatrix.Therefore,the texture intensities of bothαandβphases were weakened owing to the dynamic recrystallization(DRX)of the two phases in the equiaxed microstructure.While,with regard to the lamellar microstructure,dynamic recovery(DRV)of theβphase predominated,forming elongatedβsubgrains.Besides,theαandβmatrix in lamellar microstructures obeyed the Burgers orientation relationship,which was gradually broken down until the final reduction.Lastly,the{1101}twinning exhibits a strong size effect.With the continuous DRX ofαphases,theα-twinning is suppressed owing to progressive grain refinement.The activation ofβ-twinning,namely{332}?113?and{112}?111?,in nearβ-Ti alloys is heavily dependent on the deficientβ-stabilizing elements and the local stress concentration.These findings provide an effective way to obtain ultra-fine grain microstructures of this alloy. | Wei Chen Hande Wang Y.C.Lin Xiaoyong Zhang Chao Chen Yaping Lv Kechao Zhou | 2020 | Journal of Materials Science & Technology2020，36，8： | 3 |
| 17 | Gastrointestinal and hepatic complications of hematopoietic stem cell transplantation显示文摘Recognition and management of gastrointestinal and hepatic complications of hematopoietic stem cell transplantation has gained increasing importance as indications and techniques of transplantation have expanded in the last few years.The transplant recipient is at risk for several complications including conditioning chemotherapy related toxicities,infections,bleeding,sinusoidal obstruction syndrome,acute and chronic graftversus-host disease(GVHD) as well as other long-term problems.The severity and the incidence of many complications have improved in the past several years as the intensity of conditioning regimens has diminished and better supportive care and GVHD prevention strategies have been implemented.Transplant clinicians,however,continue to be challenged with problems arising from human leukocyte antigen-mismatched and unrelated donor transplants,expanding transplant indications and age-limit.This review describes the most commonly seen transplant related complications,focusing on their pathogenesis,differential diagnosis and management. | Hande H Tuncer Naveed Rana Cannon Milani Angela Darko Samer A AlHomsi | 2012 | World Journal of Gastroenterology2012，18，16： | 3 |
| 18 | Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid显示文摘Addiction to synthetic cannabinoids(SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation(AGD) and hepatic portal venous gas(HPVG),with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic followup was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG,which can be managed non-surgically despite the findings of acute abdomen. | Mert Mahsuni Sevinc Erdem Kinaci Savas Bayrak Aytul Hande Yardimci Ekrem Cakar Hasan Bektas | 2015 | World Journal of Gastroenterology2015，21，37： | 3 |
| 19 | Genetics and epigenetics of liver cancer显示文摘 | Cigdem Ozen Gokhan Yildiz Alper Tunga Dagcan Dilek Cevik Aysegul Ors Umur Keles Hande Topel Mehmet Ozturk | 2013 | New BIOTECHNOLOGY2013，，4： | 3 |
| 20 | Correlations between the Maximum Standard Uptake Value of Positron Emission Tomography/Computed Tomography and Laboratory Parameters before and after Treatment in Patients with Lymphoma显示文摘 | Edip Ucar Hulya Yalcin Gamze Hande Kavvasoglu Gul Ilhan | 2018 | Chinese Medical Journal2018，，15： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员