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| 1 | Interactions of IL-12A and IL-12B Polymorphisms on the Risk of Cervical Cancer in Chinese Women显示文摘 | Chen, X. J. Han, S. P. Wang, S. N. Zhou, X. Y. Zhang, M. F. Dong, J. Shi, X. Y. Qian, N. F. Wang, X. R. Wei, Q. Y. Shen, H. B. Hu, Z.B. | 2009 | 南京医科大学学报(自然科学版)2009，29，3： | 16 |
| 2 | Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke显示文摘 | Luo, C. X. Jiang, J. Zhou, Q. G. Zhu, X. J. Wang, W. Zhang, Z. J. Han, X. Zhu, D. Y. | 2007 | 南京医科大学学报(自然科学版)2007，27，10： | 13 |
| 3 | Pathological and biochemical alterations of astrocytes in ovariectomized rats injected with D-galactose:A potential contribution to Alzheimer's disease processes显示文摘Astrocytes are implicated in the pathological changes of Alzheimer's disease. Our previous studies have demonstrated that estrogen deprivation and oxidative stress act synergistically to accelerate the progress of Alzheimer's disease. Long-term D-galactose injection combined with ovariectomy may serve as a rodent model for Alzheimer's disease. To address the potential contribution of astroglia to the Alzheimer's disease pathogenesis, we investigated pathological and biochemical alterations of astrocytes under this animal model. Ovadectomized rats injected with D-galactose for 2 weeks showed extensive localization of glial fibrillary acidic protein immunoreactive astrocytes and slightly elevated glutathione levels in the hippocampus without significant impairments in the water maze test and deficits of the cholinergic analyses, compared to the saline-injected rats. Ovariectomized rats injected with D-galactose for 6 weeks, however, exhibited degeneration of astrocytes and decreased glutathione levels in the hippocampus, accompanied with severe dysfunction of behavioral test and deficiency of cholinergic terminals. Electron microscopy further confirmed the pathological changes of astrocytes, especially in the aggregated area of synapse and brain microvessels. Consistent with degeneration of perivascular astrocytic endfeet, analysis of the horseradish peroxidase demonstrated an impairment of the blood-brain barrier permeability. These findings indicate that biochemical and pathological alterations of astrocytes may partially contribute to exacerbating neuronal deficits in the course of Alzheimer's disease. Restoring neuroprotective potential of astrocytes may be a useful therapeutic target for Alzheimer's disease and other neurodegenerative diseases. | Hua, X. D. Lei, M. Ding, H. Han, Q. Y. Hu, G. Xiao, M. Nanjing Med Univ,Dept Anat Histol & Pharmacol,Jiangsu Prov Key Lab Neurodegenerat,Nanjing 210029,Peoples R China. | 2008 | 南京医科大学学报(自然科学版)2008，28，6： | 4 |
| 4 | A New Perspective about Climate Change显示文摘 | K. B. Mao Y. Ma T.R. Xu Q. Liu J Q. Han L. Xia X. Y. Shen T. J. He | 2015 | 地球科学期刊(中英文版)2015，5，1： | 4 |
| 5 | Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest显示文摘 | Meng, Z. X. Nie, J. Ling, J. J. Sun,J. X. Zhu,Y. X. Gao,L. Lv,J. H. Zhu,D. Y. Sun,Y. J. Han,X. | 2009 | 南京医科大学学报(自然科学版)2009，29，3： | 4 |
| 6 | A Lesion-Mimic Syntaxin Double Mutant in Arabidopsis Reveals Novel Complexity of Pathogen Defense Signaling显示文摘损害模仿 Arabidopsis 异种, syp121 syp122,组成地表示表明小径的水杨酸酸(SA ) 并且有低穿入抵抗到粉的霉真菌。损害模仿显型的基因分析在植物扩展了我们规划房间死亡(PCD ) 的理解。在 syp121 syp122 表明基因的 SA 的 Inactivation 仅仅部分救损害模仿显型,显示另外的防卫贡献 PCD。整个染色体 transcriptome 分析证实了那知道的导致 SA 的抄本,以及众多的其它病原体反应抄本,在 syntaxin 基因的 inactivation 以后是起来调整的。syp121 syp122 的 suppressor 异种分析表明 FMO1, ALD1,和 PAD4 为损害开发是重要的。EDS1, NDR1, RAR1,和 SGT1b 的变异的等位基因部分也救了损害模仿显型,建议那变异的 syntaxin 基因刺激 TIR-NB-LRR 和 CC-NB-LRR-type 电阻。syntaxin 两倍大美人加强了粉的导致霉的象 HR 一样回答。发信号的这要求的功能的 PAD4 然而并非功能的 SA。然而,发信号的 SA 加强了 PAD4 依赖的象 HR 一样反应。四倍的异种的分析建议 EDS5 和 SID2 授与分开的 SA 独立的发信号功能,并且那 FMO1 和 ALD1 调停 NPR1 依赖的 SA 独立的信号。这些研究加亮多重小径的贡献到防卫和点到他们的相互作用的复杂性。 | Ziguo Zhang Andrea Lenk Mats X. Andersson Torben Gjetting Carsten Pedersen Mads E. Nielsen Mari-Anne Newman Bi-Huei Hou Shauna C. Somerville Hans Thordal-Christensen | 2008 | Molecular Plant2008，1，3： | 3 |
| 7 | Effect of power ultrasound on solidification of aluminum A356 alloy显示文摘 | X. Jian H. Xu T.T. Meek Q. Han | 2004 | Materials Letters2004，，2： | 3 |
| 8 | Refinement of eutectic silicon phase of aluminum A356 alloy using high-intensity ultrasonic vibration显示文摘 | X. Jian T.T. Meek Q. Han | 2005 | Scripta Materialia2005，，： | 2 |
| 9 | A Clinical Study of HB sAg‐Activated Dendritic Cells and Cytokine‐Induced Killer Cells During the Treatment for Chronic Hepatitis B显示文摘 | Y.‐J. Ma M. He J.‐A. Han L. Yang X.‐Y. Ji | 2013 | Scand J Immunol2013，，4： | 2 |
| 10 | Ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug ( LIFT ‐Plug): a new technique for fistula‐in‐ano显示文摘 | J. G. Han B. Q. Yi Z. J. Wang Y. Zheng J. J. Cui X. Q. Yu B. C. Zhao X. Q. Yang | 2013 | Colorectal Dis2013，，5： | 2 |
| 11 | Development of constitutive relationship model of Ti600 alloy using artificial neural network显示文摘 | Y. Sun W.D. Zeng Y.Q. Zhao Y.L. Qi X. Ma Y.F. Han | 2010 | Computational Materials Science2010，，3： | 2 |
| 12 | Spatial analysis for spring bloom and nutrient limitation in Xiangxi bay of three Gorges Reservoir显示文摘 | L. Ye X. Q. Han Y. Y. Xu Q. H. Cai | | Environmental Monitoring and Assessment (-)0，，： | 2 |
| 13 | Changes in phosphorus fractions, sorption and release in Udic Mollisols under different ecosystems显示文摘 | C. Song X. Z. Han C. Tang | 2007 | Biology and Fertility of Soils2007，，1： | 1 |
| 14 | Inhibition of Forkhead Box 01 Protects Pancreatic beta-Cells against Dexamethasone- Induced Dysfunction显示文摘 | Zhang, X. F. Yong, W. Lv, J.H. Zhu, Y. X. Zhang, J. J. Chen, F. Zhang, R. H. Yang, T. Sun,Y.J. Han, X. | 2009 | 南京医科大学学报(自然科学版)2009，29，11： | 1 |
| 15 | Identification of new altered genes in rat cochleae with noise-induced hearing loss显示文摘 | Han Y Hong L Zhong C Chen Y. Wang Y. Mao X. Zhao D. Qiu J | | 0，，： | 1 |
| 16 | Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism显示文摘 | R. Han R. Lai Q. Ding Z. Wang X. Luo Y. Zhang G. Cui J. He W. Liu Y. Chen | 2007 | Diabetologia2007，，9： | 1 |
| 17 | Spatial analysis for spring bloom and nutrient limitation in Xiangxi bay of three Gorges Reservoir显示文摘 | L. Ye X. Q. Han Y. Y. Xu Q. H. Cai | 2007 | Environmental Monitoring and Assessment (-)2007，，1： | 1 |
| 18 | 查看详情显示文摘 | H Jing Y A Han J L Chen Y. X. Miao | | Chinese Physics Letters0，，： | 1 |
| 19 | A genetic linkage map for azuki bean [Vigna angularis (Willd.) Ohwi & Ohashi]显示文摘 | O. K. Han A. Kaga T. Isemura X. W. Wang N. Tomooka D. A. Vaughan | 2005 | Theoretical and Applied Genetics2005，，7： | 1 |
| 20 | 查看详情显示文摘 | Zhou F Han X. L Lu X. Y | | 0，，： | 1 |
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