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	题名	作者	年代	出处	被引量
1	Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.	V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun	2003	World Journal of Gastroenterology2003，9，10：	5
2	Evaluation of Diverting Ileostomy in Laparoscopic Low Anterior Resection for Rectal Cancer显示文摘	Tayfun Karahasanoglu Ismail Hamzaoglu Bilgi Baca Erman Aytac Ilknur Erenler Sibel Erdamar	2011	Asian Journal of Surgery2011，，2：	2
3	Im- pact of increased body mass index on laparoscopic surgery for rectal cancer显示文摘	KARAHASANOGLU T HAMZAOGLU I BACA B	2011	Eur Surg Res2011，46，2：	1
4	Posterior vertebral column resection in severe spinal deformities显示文摘	Hamzaoglu A Alanay A Ozturk C Sarier M Karadereler S Ganiyusufoglu K	2011	Spine2011，36，5：	1
5	Posterior vertebral column resection in severe spinal deformities显示文摘	Hamzaoglu A Alanay A Ozturk C	2011	Spine(Phila Pa 1976)2011，36，5：	1
6	Test set compaction algorithms for combinational circuits显示文摘	HAMZAOGLU I JANAK H P	2000	IEEE Transactions on Computer-aided Design of Integrated Circuits and Systems2000，19，8：	1
7	Totally laparoscopic approach for the treatment of right colon cancer: A technical critique显示文摘	Ilknur Erguner Erman Aytac Bilgi Baca Ismail Hamzaoglu Tayfun Karahasanoglu	2012	Asian Journal of Surgery2012，，：	1
8	New techniques for deterministic test pattern generation 显示文摘	Patel J H	1999	Electronic Testing: Theory and Application1999，15，：	1
9	Assessment of curve flex-ibility in adolescent idiopathic scoliosis显示文摘	Hamzaoglu A Talu U Tezer M	2005	Spine(Phila Pa1976)2005，30，14：	1
10	Assessment of curve flexibility inadolescent idiopathic scoliosis显示文摘	Hamzaoglu A Talu U Tezer M	2005	Spine2005，30，14：	1
11	An anterior approach to the cerviothoracic junction of the spine modified osteotomy of manubrium sterni and clavicle显示文摘	Sar C Hamzaoglu A Talu U	1999	J Spinal Disord1999，12，2：	1
12	Posterior vertebrectomy in kyphosis, scoliosis and kyphoscoliosis due to hemivertebra显示文摘	Mehmet Aydogan Cagatay Ozturk Mehmet Tezer Cuneyt Mirzanli Omer Karatoprak Azmi Hamzaoglu	2008	Journal of Pediatric Orthopaedics B2008，，1：	1
13	Posterior only pediclescrew instrumentation with intraoperative halo-femoral traction in thesurgical treatment of severe scoliosis(>100 degrees)显示文摘	Hamzaoglu A Ozturk C Aydogan M	2008	Spine(Phila Pa 1976)2008，33，9：	1
14	Posterior only pedicle screw instrumentation with intraoperative halo-femoral traction in the surgical treatment of severe scoliosis (>100°) 显示文摘	Hamzaoglu A Ozturk C Aydogan M	2008	Spine2008，33，9：	1
15	Transumbilieal To- tally Laparoscopic Single-Port Nissen Fundoplication: A New Method of Liver Retraction: The Istanbul Technique显示文摘	Hamzaoglu I Karahasanoglu T Aytac E	2010	J Gastroin- test Surg2010，14，6：	1
16	Single - port lapa- roscopic sphincter -saving mesorectal excision for rectal cancer: report of the first 4 human cases 显示文摘	Hamzaoglu I Karahasanoglu T Baca B	2011	Arch Surg2011，146，1：	1
17	Test set compaction algorithms for combinationalcircuits显示文摘	Hamzaoglu Ilker Patel Janak H	2000	IEEE Transactions on ComputerAided of Integrated Circuits and Systems2000，19，8：	1
18	Test set compaction algorithms for combinational circuits 显示文摘	Hamzaoglu I Patel J H	2000	IEEE Transactions on Computer-Aided Design Circuits and Systems2000，19，8：	1
19	Single-port laparoscopic sphincter-saving mesorectal excision for rectal cancer: report of the first 4 human cases显示文摘	Hamzaoglu I Karahasanoglu T Baca B	2011	Arch Surg2011，146，1：	1
20	Single-port laparoscopic sphincter-saving mesorectal excision for rectal cancer:report of the first 4 human cases显示文摘	Hamzaoglu I Karahasanoglu T Baca B	2011	Arch Surg2011，146，1：	1

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