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| 1 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 2 | Evaluation of Diverting Ileostomy in Laparoscopic Low Anterior Resection for Rectal Cancer显示文摘 | Tayfun Karahasanoglu Ismail Hamzaoglu Bilgi Baca Erman Aytac Ilknur Erenler Sibel Erdamar | 2011 | Asian Journal of Surgery2011，，2： | 2 |
| 3 | Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomid- ate: a randomized, double - blind controlled trial 显示文摘 | MIZRAK A KORUK S BILGI M | 2010 | J Surg Res2010，159，1： | 1 |
| 4 | An investigation of some Schiff bases as corrosion inhibitors for austenitic chromiumnickel steel in H2SO4显示文摘 | Bilgie S Caliskan N | 2001 | J Appl Electrochem2001，31，： | 1 |
| 5 | Comparison of the effects of fixed and removable functional appliances on the skeletal and dentoalveolar structures显示文摘 | Bilgi F Hamamci O Ba saran G | 2011 | Aust Orthod J2011，27，2： | 1 |
| 6 | Pretreatmentwithdexmedetomi- dine or thiopental decreases myoclonus after etomidate: a random- ized, double- blind controlled trial显示文摘 | Mizrak A Koruk S Bilgi M | 2010 | J Surg Res2010，159，1： | 1 |
| 7 | Imatinib and Panax ginseng:A Potential Interaction Resulting in Liver Toxicity显示文摘 | Bilgi N Bell K Ananthakrishnan AN | 2010 | Annals of Pharmacotherapy2010，44，5： | 1 |
| 8 | Mean platelet volume increase after amoxfen, but not after anastrazole in adjuvant therapy of breast cancer显示文摘 | Karagoz B Bilgi O Alacacioglu A | 2012 | Med Oncol2012，27，2： | 1 |
| 9 | CD8+CD28- cells andCD4+CD25+ regulatoU T cells in the peripheral blood of advanced stage lung vaneer patients 显示文摘 | Karagoz B Bilgi O Gumiis M et aI | 2010 | Med Oncol2010，27，1： | 1 |
| 10 | Comparison of the effects of low-flow and high-flow inhalational anaesthesia with ni- trous oxide and desflurane on mucociliary activity and pul- monary function tests 显示文摘 | Bilgi M Goksu S Mizrak A | 2011 | Eur J Anaesthesiol2011，28，4： | 1 |
| 11 | Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate:A randomized,double-blind controlled trial显示文摘 | Mizrak A Koruk S Bilgi M | 2010 | J Surg Res2010，159，： | 1 |
| 12 | Predicting radial overcut in deep holes drilled by shaped tube electrochemical machining显示文摘 | BILGI D S KUMAR R JAIN V K | 2008 | Int J Adv Manuf Technol2008，，39： | 1 |
| 13 | Nesfatin-1 in advanced lungcancer patients with weight loss显示文摘 | Cetinkaya H Karagoz B Bilgi 0 | 2013 | Regul Pept2013，181，： | 1 |
| 14 | Totally laparoscopic approach for the treatment of right colon cancer: A technical critique显示文摘 | Ilknur Erguner Erman Aytac Bilgi Baca Ismail Hamzaoglu Tayfun Karahasanoglu | 2012 | Asian Journal of Surgery2012，，： | 1 |
| 15 | Role of TIMP-2 in fascia transversalis on development of inguinal hernias显示文摘 | Abci I Bilgi S Altan A | 2005 | J Invest Surg2005，18，3： | 1 |
| 16 | Comparison of the effects of low-flow and high-flow inhalational anaesthesia with nitrous oxide and desflurane on mucociliary activity and pulmonary function tests 显示文摘 | Bilgi M Goksu S Mizrak A | 2011 | Eur J Anaesthesiol2011，28，4： | 1 |
| 17 | Long term survival with the combination of interferon and chemotherapy in metastatic melanoma显示文摘 | KaragOz B Bilgi O Ozgtin A | 2015 | J Egypt Natl Canc Inst2015，27，3： | 1 |
| 18 | Clinical and magnetic resonance imaging findings of HIV-Negative patients with neurosyphilis显示文摘 | Guises C Bilgie B Topcular B | 2007 | J Neurol2007，254，3： | 1 |
| 19 | Nesfatin-1 in advanced lung cancer patients with weight loss显示文摘 | Cetinkaya H Karagz B Bilgi O | 2013 | Regnal Pept2013，181，： | 1 |
| 20 | Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate:a randomized,double-blind controlled trial显示文摘 | Mizrak A Koruk S Bilgi M | | 0，，01： | 1 |
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