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46篇 您的检索式:作者名="Hamzaoglu A"
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1Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun 2003World Journal of Gastroenterology2003,9,10:5
2Posterior vertebral column resection in severe spinal deformities显示文摘Hamzaoglu A Alanay A Ozturk C Sarier M Karadereler S Ganiyusufoglu K 2011Spine2011,36,5:1
3Posterior vertebral column resection in severe spinal deformities显示文摘Hamzaoglu A Alanay A Ozturk C 2011Spine(Phila Pa 1976)2011,36,5:1
4Assessment of curve flex-ibility in adolescent idiopathic scoliosis显示文摘Hamzaoglu A Talu U Tezer M 2005Spine(Phila Pa1976)2005,30,14:1
5Assessment of curve flexibility inadolescent idiopathic scoliosis显示文摘Hamzaoglu A Talu U Tezer M 2005Spine2005,30,14:1
6An anterior approach to the cerviothoracic junction of the spine modified osteotomy of manubrium sterni and clavicle显示文摘Sar C Hamzaoglu A Talu U 1999J Spinal Disord1999,12,2:1
7Posterior only pediclescrew instrumentation with intraoperative halo-femoral traction in thesurgical treatment of severe scoliosis(>100 degrees)显示文摘Hamzaoglu A Ozturk C Aydogan M 2008Spine(Phila Pa 1976)2008,33,9:1
8Posterior only pedicle screw instrumentation with intraoperative halo-femoral traction in the surgical treatment of severe scoliosis (>100°) 显示文摘Hamzaoglu A Ozturk C Aydogan M 2008Spine2008,33,9:1
9Simultaneous surgical treatment in congenital scoliosis and/or kyphosis associated with intraspinal abnormalities显示文摘Hamzaoglu A Ozturk C Tezer M 2007Spine2007,32,25:1
10Assessment of curve flexibility in adolescent idiopathic scoliosis显示文摘Hamzaoglu A Talu U Tezer M 2005Spine(Phila Pa 1976)2005,30,14:1
11Posterior vertebral column resection in severe spinal deformities: a total of 102 cases显示文摘Hamzaoglu A Alanay A Ozturk C 2011Spine (Phila Pa 1976)2011,36,5:1
12Posterior vertebral column resection in severe spinal deformities显示文摘Hamzaoglu A Alanay A Ozturk C 2011Spine2011,36,5:1
13Assessment of curve flexibility in adolescent idiopathic scoliosis显示文摘Hamzaoglu A Talu U Tezer M 2005Spine2005,30,14:1
14Posterior only pedicle screw instrumentation with intraoperative halo-femoral traction in the surgical treatment of severe scoliosis (>100 degrees)显示文摘Hamzaoglu A Ozturk C Aydogan M 2008Spine (Phila Pa 1976)2008,33,9:1
15Posterior vertebral column resection in severe spinal deformities显示文摘Hamzaoglu A Alanay A Ozturk C 2011Spine2011,36,5:1
16Simultaneous surgical treatment in congenital scoliosis and/or kyphosis associated with intraspinal abnormalities显示文摘Hamzaoglu A Ozturk C Tezer M 2007Spine (Phila Pa 1976)2007,32,25:1
17Posterior only pedicle screw instrumentation with intraoperative halo-femoral traction in the surgical treatment of severe scoliosis ( > 100 degrees)显示文摘Hamzaoglu A Ozturk C Aydogan M 2008Spine(Phila Pa 1976)2008,33,9:1
18Posterior vertebral column resection in severe spinal deformities:a total of 102cases显示文摘Hamzaoglu A Alanay A Ozturk C 2011Spine2011,36,5:1
19Assessment of curve flexibility in adolescent idiopathic scoliosis显示文摘Hamzaoglu A Talu U Tezer M 2005Spine2005,30,14:1
20Simultaneous surgical treat- ment in congenital scoliosis and/or kyphosis associated with intraspi- hal abnormalities 显示文摘Hamzaoglu A Ozturk C Tezer M 2007Spine ( Phila Pa 1976 )2007,32,25:1
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