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| 1 | Lipid droplets and mitochondria are anchored during brown adipocyte differentiation显示文摘Dear Editor,Brown adipose tissue(BAT)acts as a site of non-shivering thermogenesis in mammals including adult humans(Ned-ergaard and Cannon,2010).Prolonged cold exposure can induce the acquisition of thermogenic function in white adipose tissue(WAT)with the cells that have undergone the'browning'process being referred to as beige cells(Wu et al.,2013).Both mainly use mitochondrial p-oxidation of fatty arid(FA)from lipid drnplotc(I He)in maintaining hnHy temperature.The efficiency of hydrophobic FA transport between two organelles in aqueous cytoplasm has been challenged.Understanding the mechanism underlying the interaction between these two organelles is essential for animal physiology as well as for the development of therapies to treat metabolic diseases(Benador et al.,2018). | Liujuan Cui Mirza Ahmed Hammad Shuyan Zhang Bin Liang Pingsheng Liu | 2019 | Protein & Cell2019，10，12： | 8 |
| 2 | Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience显示文摘BACKGROUND: Reports of liver transplantation(LT) in patients with mixed hepatocellular carcinoma/cholangiocarcinoma(HCC/CC) and intrahepatic cholangiocarcinoma(ICC) are modest and have been mostly retrospective after pathological categorization in the setting of presumed HCC. Some studies suggest that patients undergoing LT with small and unifocal ICC or mixed HCC/CC can achieve about 40%-60% 5-year post-transplant survival. The study aimed to report our experience in patients undergoing LT with explant pathology revealing HCC/CC and ICC.METHODS: From a prospectively maintained database, we performed cohort analysis. We identified 13 patients who underwent LT with explant pathology revealing HCC/CC or ICC. RESULTS: The observed recurrence rate post-LT was 31%(4/13) and overall survival was 85%, 51%, and 51% at 1, 3 and 5 years, respectively. Disease-free survival was 68%, 51%, and 41% at 1, 3 and 5 years, respectively. In our cohort, four patients would have qualified for exception points based on updated HCC Organ Procurement and Transplantation Network imaging guidelines. CONCLUSIONS: Lesions which lack complete imaging characteristics of HCC may warrant pre-LT biopsy to fully elucidate their pathology. Identified patients with early HCC/CC or ICC may benefit from LT if unresectable. Additionally, incorporating adjunctive perioperative therapies such as in the case of patients undergoing LT with hilar cholangiocarcinoma may improve outcomes but this warrants further investigation. | Mohammed Elshamy Naftali Presser Abdulrahman Y Hammad Daniel J Firl Christopher Coppa John Fung Federico N Aucejo | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，3： | 6 |
| 3 | 澳大利亚人乳头状瘤病毒疫苗计划实施5年对年轻人群生殖器疣患病情况的影响:国家调查数据分析显示文摘目的评估2007年中开始的澳大利亚人乳头状瘤病毒(HPV)疫苗计划对生殖器疣患病情况的影响。设计国家调查数据趋势分析。数据来源数据收集于2004--2011年度澳大利亚8所性健康服务机构;其中2所最大的临床中心收集了自我报告的本中心2009年度HPV疫苗现状。研究对象2004--2011年度首次就诊的85770名澳大利亚出生的国民;其中7686(9.0%)名患生殖器疣。主要结局测量比较前疫苗时期(2004—2007年中)和疫苗时期(2007年中-2001年末)不同人群生殖器疣新发病率变化趋势。结果疫苗时期21岁以下和21~30岁女性诊断患有生殖器疣的比例明显下降,发病率分别从2007年度的11.5%和11.3%下降至2011年度的0.85%和3.1%,P均〈0.001。在30岁以上的女性中未发现发病率的明显下降。在21岁以下和21~30岁异性恋男性人群中疫苗时期生殖器疣的发病率较前疫苗时期明显下降,分别由2007年度12.1%和18.2%下降至2011年度2.2%和8.9%,P均〈0.001。30岁以上的异性恋男性人群中发病率无明显下降。2011年235名21岁以下女性在使用HPV疫苗后无新发生殖器疣病例。结论年轻女性生殖器疣发病率的显著下降和2011年度部分年轻女性使用疫苗后的零发病率,说明HPV疫苗获得实验室外的良好功效。异性恋男性生殖器疣发病率的显著下降可能是由于群体免疫所致。 | Hammad Ali,lecturer Basil Donovan, professor HandanWand,senior lecturer Tim R H Read, sexual health physician David G Regan,senior lecturer Andrew E Grulich, professor Christopher K FaMey, professor Rebecca J Guy, associate professor 尹婕(译) 潘凌亚(校) | 2013 | 英国医学杂志中文版2013，16，4： | 4 |
| 4 | Offshore Carbonate Facies Characterization and Reservoir Quality of Miocene Rocks in the Southern Margin of South China Sea显示文摘Carbonate rocks are important hydrocarbon reservoirs around the globe and in Southeast Asia a key one,particularly,is the Central Luconia province.Understanding the internal characteristics,distribution,geometry and lateral extent of these rocks is essential for exploration and production success.Detailed work on Miocene carbonate reservoir facies,north of Bintulu,offshore Sarawak includes qualitative and quantitative analysis of photomicrographs and reservoir quality,considering especially microporosity.Stratigraphically,these carbonates are known as Cycles IV and V and are represented by eight major facies types(F-1 to F-8).They comprise:coated grain packstone(F-1)(av.Ф=3%,av.Kh=0.5 m D)(av=Average;?=total porosity,and Kh=permeability);massive coral lime grainstone(F-2)(av.Ф=14.7%,av.Kh=6 m D);oncolite lime grain-dominated packstone(F-3)(av.Ф=10%,av.Kh=4 m D);skeletal lime/dolo-packstone(F-4)(av.Ф=15%,av.Kh=4.6 m D);coral(platy)lime mud-dominated packstone(F-5)(av.Ф=4%,av.Kh=0.5 m D);coral(branching)lime-dominated pack-grainstone(F-6)(av.Ф=15%,av.Kh=1 m D);cross-bedded skeletal lime packstone(F-7)(av.Ф=20%,av.Kh=2 m D);and bioturbated carbonate mudstone/chalk(F-8)(av.Ф=8%,av.Kh=0.8 m D).Study of thin sections reveals that red algae,foraminifera,and corals are the dominant fossil components with a minor admixture of skeletal fragments of echinoderms,bivalves,bryozoans,and green algae.All parameters,e.g.,facies characterization,petrography,porosity–permeability value,and microporosity value were utilized to obtain a reliable reservoir quality.The microporosity value was quantified using digital image analysis software and is significant for recognition of good reservoir quality.Consideration of the presence of microporosity against the total porosity in the carbonate rocks has improved the correlation coefficient(R2)value,which has increased from 0.51 to 0.82. | Hammad Tariq JANJUHAH Abubaker ALANSARI | 2020 | Acta Geologica Sinica(English Edition)2020，94，5： | 4 |
| 5 | Endoscopic assessment and management of early esophageal adenocarcinoma显示文摘Esophageal carcinoma affects more than 450000people worldwide and the incidence is rapidly increasing.In the United States and Europe,esophageal adenocarcinoma has superseded esophageal squamous cell carcinoma in its incidence.Esophageal cancer has a high mortality rates secondary to the late presentation of most patients at advanced stages.Endoscopic screening is recommended for patients with multiple risk factors for cancer in Barrett’s esophagus.These risk factors include chronic gastroesophageal reflux disease,hiatal hernia,advanced age,male sex,white race,cigarette smoking,and obesity.The annual risk of esophageal cancer is approximately 0.25%for patients without dysplasia and 6%for patients with high-grade dysplasia.Twenty percent of all esophageal adenocarcinoma in the United States is early stage with disease confined to the mucosa or submucosa.The significant morbidity and mortality of esophagectomy make endoscopic treatment an attractive option.The American Gastroenterological Association recommends endoscopic eradication therapy for patients with high-grade dysplasia.Endoscopic modalities for treatment of early esophageal adenocarcinoma include endoscopic resection techniques and endoscopic ablative techniques such as radiofrequency ablation,photodynamic therapy and cryoablation.Endoscopic therapy should be precluded to patients with no evidence of lymphovascular invasion.Local tumor recurrence is low after endoscopic therapy and is predicted by poor differentiation of tumor,positive lymph node and submucosal invasion.Surgical resection should be offered to patients with deep submucosal invasion. | Ghassan M Hammoud Hazem Hammad Jamal A Ibdah | 2014 | World Journal of Gastrointestinal Oncology2014，6，8： | 4 |
| 6 | Colon mucosal neoplasia referred for endoscopic mucosal resection:Recurrence of adenomas and prediction of submucosal invasion显示文摘BACKGROUND Endoscopic mucosal resection(EMR)is an effective and minimally invasive alternative to surgery for large polyps and laterally spreading lesions.Gross morphology and surface characteristics may help predict submucosal invasion of the lesion(SMIL)during endoscopic evaluation.This is one of the largest singlecenter studies reporting endoscopic mucosal resection for larger(≥20 mm)colorectal lesions in the United States.AIM To determine the recurrence rate of adenomas and endoscopic features that may predict submucosal invasion of colonic mucosal neoplasia.METHODS This is a retrospective cohort study of all the patients referred for endoscopic mucosal resection for lesions≥20 mm,spanning a period from January 2013 to February 2017.The main outcome measure was identifying features that may predict submucosal invasion of mucosal lesions and predict recurrence of adenomas on follow-up surveillance colonoscopy performed at 4-6 mo.RESULTS A total of 480 patients with 500 lesions were included in the study.The median age was 68(Inter quantile range:14)with 52%males.The most common lesion location was ascending colon(161;32%).Paris classification 0-IIa(Flat elevation of mucosa-316;63.2%);Kudo Pit Pattern IIIs(192;38%)and Granular surface morphology(260;52%)were most prevalent.Submucosal invasion was present in 23(4.6%)out of 500 lesions.The independent risk factors for SMIL were Kudo Pit Pattern IIIL+IV and V(Odds ratio:4.5;P value<0.004)and Paris classification 0-IIc(Odds ratio:18.2;P value<0.01).Out of 500,354 post-endoscopic mucosal resection scars were examined at surveillance colonoscopy.Recurrence was noted in 21.8%(77 cases).CONCLUSION There was overall low prevalence of SMIL in our study.Kudo pit pattern(IIIL+IV and V)and Paris classification 0-IIc were the only factors identified as an independent risk factor for submucosal invasion.The independent risk factor for recurrence was adenoma size(>40 mm).Almost all recurrences(98.8%)were treated endoscopically. | Mamoon Ur Rashid Neelam Khetpal Hammad Zafar Saeed Ali Evgeny Idrisov Yuan Du Assaf Stein Deepanshu Jain Muhammad Khalid Hasan | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，7： | 3 |
| 7 | Forest Cover Change Assessment in Conflict-affected Areas of Northwest Pakistan: the Case of Swat and Shangla Districts显示文摘This study examines the spatial and temporal forest cover changes in Swat and Shangla districts to understand the deforestation pattern in context of the recent security conflict in these districts. We used multi-resolution satellite images to assess the long term deforestation from 2001 to 2009 and also to identify episodic forest cutting areas appeared during the conflict period of Oct. 2007 - Oct. 2008. There are only 58 ha of deforestation identified during the conflict period while 1268 ha of gross annual deforestation were assessed during last eight years. Most of the deforestation patches persist around the administrative boundaries at sub-district levels (tehsils) which can be attributed to ambiguity in unclear jurisdiction between the forest official. The results highlight that the forest cutting appeared in Swat and Shangla during the conflict period is not as significant when compared with the long term deforestation pattern in the area. On the one side the results of the study are supportive to the picture that emerges from international studies which report high rate of deforestation in the country and on the other side it negates any relation between the security situation and the increasing deforestation in the north western Pakistan. The study concludes that deforestation assessments require verification by independent sources of data, such as satellite imagery to improve our understanding of deforestation processes. | Faisal Mueen QAMER Sawaid ABBAS Rashid SALEEM Khurram SHEHZAD Hassan ALI Hammad GILANI | 2012 | Journal of Mountain Science2012，9，3： | 3 |
| 8 | Secure design for cloud control system against distributed denial of service attack显示文摘现在,云计算的开发把力量给了抑制资源的网络控制系统(NCS ) 采购重计算到云服务器。然而,云计算的发展关于在云和控制系统之间的电子物理的连接生产了许多安全挑战。在控制系统和云服务者之间的连接能受到分布式的拒绝服务(DDoS ) 由一个攻击者的攻击使动摇 NCS。在这份报纸,我们将由为如此的系统造安全机制处理这个问题。我们将为 NCS 的更好稳定的性能设计一条察觉途径和一条缓解途径。为了在 DDoS 的时候保证 NCS 的稳定性,攻击,当有从云可得到的不再实时的答案时,我们将也为云控制系统(CCS ) 设计切换的机制(SM ) 。最后,我们将把建议机制用于无人的 arial 车辆(UAV ) 。我们的模拟结果证明机制在 DDoS 攻击下面在 NCS 的稳定性和保护工作很好。 | Yasir ALI Yuanqing XIA Liang MA Ahmad HAMMAD | 2018 | Control Theory and Technology2018，16，1： | 3 |
| 9 | Predictions of future hydrological conditions and contribution of snow and ice melt in total discharge of Shigar River Basin in Central Karakoram,Pakistan显示文摘The high mountains of Hindu-Kush Karakoram and Himalaya(HKKH) contain a large volume of snow and ice, which are the primary sources of water for the entire mountainous population of HKKH. Thus, knowledge of these available resources is very important in relation to their sustainable use. A Modified Positive Degree Day Model was used to simulate daily discharge with the contribution of snow and ice melt from the Shigar River Basin, Central Karakoram, Pakistan. The basin covers an area of 6,921 km2 with an elevation range of 2,204 to 8,611 m a.s.l.. Forty percent of the total area is glaciated among which 20% is covered by debris and remaining 80% by clean ice and permanent snow. To simulate daily discharge, the entire basin was divided into 26 altitude belts. Remotely sensed land cover types are derived by classifying Landsat images of 2009. Daily temperature and precipitation from Skardu meteorological station is used to calibrate the glacio-hydrological model as an input variable after correlating data with the Shigar station data(r=0.88). Local temperature lapse rate of 0.0075 °C/m is used. 2 °C critical temperature is used to separate rain and snow from precipitation. The model is calibrated for 1988~1991 and validated for 1992~1997. The model shows a good Nash-Sutcliffe efficiency and volume difference in calibration(0.86% and 0.90%) and validation(0.78% and 6.85%). Contribution of snow and ice melt in discharge is 32.37% in calibration period and 33.01% is validation period. The model is also used to predict future hydrological regime up to 2099 by using CORDEX South Asia RCM considering RCP4.5 and RCP8.5 climate scenarios.Predicted future snow and ice melt contributions in both RCP4.5 and RCP8.5 are 36% and 37%, respectively. Temperature seems to be more sensitive as compared to other input variables, which is why the contribution of snow and ice in discharge varies significantly throughout the whole century. | Javed Hassan Rijan Bhakta Kayastha Ahuti Shrestha Iram Bano Sayed Hammad Ali Haleem Zaman Magsi | 2017 | Research in Cold and Arid Regions2017，9，6： | 3 |
| 10 | Structure-based protein-protein interaction networks and drug design显示文摘 | Hammad Naveed Jingdong J. Han | 2013 | Frontiers of Electrical and Electronic Engineering in China2013，8，3： | 3 |
| 11 | Clinico-epidemiological features of dengue fever in Saudi Arabia显示文摘Objective:To highlight some clinical and epidemiological features of dengue fever.Methods: All patients who were admitted to hospitals in Holly Mecca City,Saudi Arabia and were confirmed as dengue fever(DF) or dengue hemorrhagic fever(DHF) were included in this study. The data were collected from patient files and through direct interview with patients or their relatives.Cases were followed through their hospital stay.Routine laboratory investigations were done and diagnosis was confirmed by PCR.Results:Most of cases admitted in stable condition(94.37%) and only one case(1.41%) died.Dengue-1 and 3 types were the prevalent dengue viruses and cases in age group 16-44 were the most frequent(70.40%).The most common symptoms was fever reported from all cases followed by headache(74.60%),myalgia and anorexia(67.60%),back pain(59.20%) and chills(54.90%).DF represented(60.57%) of the cases while DHF represented(39.43%).About half of cases had underground water tanks for human use,5.60%had over house roof water tanks and 43.70%had both types,16.90% of these tanks were uncovered.Approximately 70.00%of cases reported presence of small collection of water nearby houses and 46.80%reported the presence of mosquitoes within their houses.Conclusions:Most dengue fever cases might be endogenous in origin due to prevalence of mosquitoes and their breeding places within the houses and in nearby localities.Control of mosquitoes and their breeding places will contribute to prevention of dengue fever. | Abdel-Hady El-Gilany Abdelaziz Eldeib Sabri Hammad | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，3： | 2 |
| 12 | Electrical Properties of Li-doped P-type ZnO Ceramics显示文摘Li-doped p-type ZnO ceramics were prepared by conventional methods according to the chemical formula Zn1-xLixO2 where x=0.5, 1.0, 1.5 and 2.0 mole fraction, respectively. The crystal structures of the prepared samples were studied by X-ray diffraction analysis. The dielectric properties (including dielectric constant ε and dielectric loss ε ) and dc-electrical conductivity [σ(Ω-1·cm-1)] were investigated. The dielectric constant ε was sharply decreased at the low frequency range and independent on frequency at high frequency range. Otherwise, the dielectric loss ε varied with frequency and showed absorption peak located from 200 Hz to 4 kHz and moved to higher frequency as the concentration of Li+ doped increased. It was found that dcelectrical conductivity logσ varied from -9 to ?5 and the energy gap width were calculated by using Arrhenius equation. The p-type conductivity of Li-doped ZnO may be attributed to the formation of a LiZn-Lii donor complex, which is limited by reducing the amount of Lii. | A.H. Salama F.F. Hammad | 2009 | Journal of Materials Science & Technology2009，25，3： | 2 |
| 13 | Prophylactic Clip Closure Reduced the Risk of Delayed Postpolypectomy Hemorrhage: Experience in 277 Clipped Large Sessile or Flat Colorectal Lesions and 247 Control Polyps显示文摘 | Hammad Liaquat Elizabeth Rohn Douglas K. Rex | 2012 | Gastrointestinal Endoscopy2012，，： | 2 |
| 14 | Prevalence of Hepatitis B Infection among Pregnant Women at Khartoum Teaching Hospital, Sudan显示文摘 | Mohammed Hammad Abuelgasim Mohammed Basheer Koko Baraka | 2015 | Journal of US-China Medical Science2015，12，2： | 2 |
| 15 | Pulmonary Hypertension in Heart Failure显示文摘 | Maya Guglin Hammad Khan | 2010 | Journal of Cardiac Failure2010，，6： | 2 |
| 16 | Microfacies and Depositional Environments of Miocene Isolated Carbonate Platforms from Central Luconia, Offshore Sarawak, Malaysia显示文摘The Luconia Province-offshore Sarawak-is a key geological unit for understanding the distribution of hydrocarbon resources in Malaysia. Nevertheless, little effort has been made to address the palaeoenvironmental characteristics of the Tertiary carbonates in the key sector of Central Luconia.We study the sedimentology and petrography of core samples from a well in Central Luconia, for which thirteen microfacies have been identified reflecting different depositional settings. This is the first microfacies scheme elaborated for Luconian carbonates. Lithofacies and microfacies distribution are compatible with deposition in a reef complex, originating around a framework reef, within the euphotic zone. Sediments were deposited in environments of backreef, reef crest, and forereef. The fair weather wave base is marked by the presence of coralline red algae, foraminifera, decreasing degree of bioclast fragmentation and other microfacies features. As a result, a depositional-environmental model is constructed, depicting a reef complex built around a framework reef developed on the margin of an isolated platform. In addition, an innovative, preliminary time series analysis of facies, microfacies and depositional environment data reveal the existence of seasonal cycles in the stacking patterns of facies and microfacies. | Hammad Tariq JANJUHAH José Antonio GáMEZ VINTANED Ahmed Mohamed Ahmed SALIM Ibrahima FAYE Mumtaz Muhammad SHAH Deva Prasad GHOSH | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 2 |
| 17 | Prevalence of pu- tative virulence factors and antimicrobial susceptibility of En- terococcus faecalis isolates from patients with dental diseas- es 显示文摘 | Salah R Dar-Odeh N Abu Hammad O | 2008 | BMC Oral Health2008，8，： | 1 |
| 18 | Controls modeling and verification for the pacific intertie HVDC 4-terminal scheme显示文摘 | Hammad A Minghetti R Hasler J | 1993 | IEEE Transactions on Power Delivery1993，8，1： | 1 |
| 19 | Automated Code Compliance Checking for Building Envelope Design 显示文摘 | Xiangyang Tan Amin Hammad Paul Fazio | 2010 | Computing in Civil Engineering2010，24，2： | 1 |
| 20 | Mycorrhizal influence on fruit yield and mineralcontent of tomato grown under salt stress显示文摘 | Al-Karaki G N Hammad R | 2001 | Journal of Plant Nutrition2001，24，8： | 1 |
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