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| 1 | Elucidation of the ‘Honeycrisp’ pedigree through haplotype analysis with a multi-family integrated SNP linkage map and a large apple (Malus×domestica) pedigree-connected SNP data set显示文摘The apple(Malus×domestica)cultivar Honeycrisp has become important economically and as a breeding parent.An earlier study with SSR markers indicated the original recorded pedigree of‘Honeycrisp’was incorrect and‘Keepsake’was identified as one putative parent,the other being unknown.The objective of this study was to verify‘Keepsake’as a parent and identify and genetically describe the unknown parent and its grandparents.A multi-family based dense and high-quality integrated SNP map was created using the apple 8 K Illumina Infinium SNP array.This map was used alongside a large pedigree-connected data set from the RosBREED project to build extended SNP haplotypes and to identify pedigree relationships.‘Keepsake’was verified as one parent of‘Honeycrisp’and‘Duchess of Oldenburg’and‘Golden Delicious’were identified as grandparents through the unknown parent.Following this finding,siblings of‘Honeycrisp’were identified using the SNP data.Breeding records from several of these siblings suggested that the previously unreported parent is a University of Minnesota selection,MN1627.This selection is no longer available,but now is genetically described through imputed SNP haplotypes.We also present the mosaic grandparental composition of‘Honeycrisp’for each of its 17 chromosome pairs.This new pedigree and genetic information will be useful in future pedigree-based genetic studies to connect‘Honeycrisp’with other cultivars used widely in apple breeding programs.The created SNP linkage map will benefit future research using the data from the Illumina apple 8 and 20 K and Affymetrix 480 K SNP arrays. | Nicholas P Howard Eric van de Weg David S Bedford Cameron P Peace Stijn Vanderzande Matthew D Clark Soon Li Teh Lichun Cai James J Luby | 2017 | Horticulture Research2017，4，1： | 9 |
| 2 | Twelve year clinical study of patients with hypoxic cor pulmonale given long term domiciliary therapy显示文摘 | Waterhouse J Howard P | 1987 | Thorax1987，42，1： | 1 |
| 3 | Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury显示文摘 | Brown L M Calfee C S Howard J P | 2013 | Ann Intensive Care2013，3，1： | 1 |
| 4 | Identification of solar sources of major geomagnetic storms between 1996 and 2000显示文摘 | Zhang J Dere K P Howard R A | 2003 | Astrophysical Jouranal2003，582，1： | 1 |
| 5 | Research strategies for safety evaluation of nanomaterials, Part IV : Risk assessment of nanopartlcles显示文摘 | TSUJI J S MAYNARD A D HOWARD C P | 2006 | Toxicological Sciences2006，89，1： | 1 |
| 6 | Use of organic carbon and loss - on - ignition to estimate soil organic matter in different soil types and horizons显示文摘 | Howard P J A Howard D M | 1990 | Biology and Fertility of soils1990，9，： | 1 |
| 7 | Health and ecological assessment of polynuclear aromatic hydrocarbons显示文摘 | Santodonato J Howard P Basu D | 1981 | J Environ Patbol Toxicol1981，5，1： | 1 |
| 8 | Leptin prevents the fall in plasma osteocalcin during starvation in male mice显示文摘 | Goldstone A P Howard J K Lord G M | 2002 | Biochem Biophys Res Commun2002，295，2： | 1 |
| 9 | Gland development on leaf surfaces of Nepeta racemosa显示文摘 | BOURETT T M HOWARD R J OKEEFE D P | 1994 | International Journal of Plant Science1994，155，： | 1 |
| 10 | Two monoclonal an tibodies(cc17,cc29)recognizing an antigen(Bo5)on bovine T lymphocytes,analogous to human CD5显示文摘 | Howard C J,Parsons K P,Jones B V | 1988 | Vet Immunol1988，13，： | 1 |
| 11 | The Arabidopsis ribonuclease gene RNS1 is tightly controlled in response to phosphate limitation显示文摘 | BARIOLA P A HOWARD C J TAYLOR C B | 1994 | The Plant Journal1994，6，5： | 1 |
| 12 | A context- based theory of recency and contiguity in free recall 显示文摘 | Sederberg P B Howard M W Kahana M J | 2008 | Psychological Review2008，115，4： | 1 |
| 13 | Immunity bovine viral diarrhea virus calves:the role of different T-cell sub-populations analysed by specific depletion in vivo with monoclonal antibodies显示文摘 | Clarke M C Sopp P | 1992 | Vet Immunolpathol1992，32，： | 1 |
| 14 | Analysis of Arithmetic Coding for Data Compression显示文摘 | Howard P G Vitter J S | 2002 | Information Processing and Management2002，28，： | 1 |
| 15 | Problems in the estimation of biological activity in soil显示文摘 | Howard P J A | 1972 | Oilkos1972，23，： | 1 |
| 16 | Relationshipbetween blood pressure and stroke risk in patients with symp-tomatic carotid occlusive disease显示文摘 | Rothwell P M Howard S C Spence J D | 2003 | Stroke2003，34，11： | 1 |
| 17 | Personal health re- cords and hypertension control: a randomized trial显示文摘 | Wagner P J Dias J Howard S | 2012 | J Am Med Inform Assoc2012，19，4： | 1 |
| 18 | Distal symmetric polyneuropathy: A definition for clinical research: Report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation显示文摘 | J D. England G S. Gronseth G Franklin R G. Miller A K. Asbury G T. Carter J A. Cohen M A. Fisher J F. Howard L J. Kinsella N Latov R A. Lewis P A. Low A J. Sumner | 2005 | Neurology2005，，2： | 1 |
| 19 | Nucleo- tide sequence of the gene for the holeforming toxin aerolysin of Aeromonas hydrophila 显示文摘 | HOWARD S P GARLAND W J GREEN M J | 1987 | Journal of Bacteriology1987，169，6： | 1 |
| 20 | Pressure and Temperature Effects in Bituminous Coal Pyrolysis:Experimental Observations and a Transient lumped-parameter Model显示文摘 | Griffin T P Howard J B Peters W A | 1994 | Fuel1994，73，4： | 1 |
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