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| 1 | Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients显示文摘胃的癌症是世界范围的第四很普通的癌症,与死亡的高率和低 5 年的幸存率。迄今为止,有为胃的癌症的有效治疗学的协议的缺乏。最近的研究建议癌症干细胞(CSC ) 为肿瘤开始,侵略,转移,和抵抗负责到 anticancer 治疗。因此,指向胃的 CSC 的治疗是吸引人的。然而,在人的胃的腺癌(GAC ) 的 CSC 没被描述。这里,我们从 GAC 病人在肿瘤纸巾和外部血识别 CSC。从肿瘤纸巾和病人的外部血被孤立的人的 GAC (GCSC ) 的 CSC 带了 CD44 和 CD54 表面标记,当注入了 immunodeficient 老鼠时,高度类似于原来的人的肿瘤的产生肿瘤,在 vitro 区分了进胃的上皮的房间,并且在 vivo 并且在 vitro 自我更新。我们的调查结果建议有效治疗学的协议必须指向 GCSC。从 GAC 病人的循环的 GCSC 的俘获也为为肿瘤转移潜在地负责的一张批评房间人口的鉴定显示出大潜力,并且为早诊断并且胃的癌症的纵的监视提供一个有效协议。 | Tie Chen Kun Yang Jianhua Yu Wentong Meng Dandan Yuan Feng Bi Fang Liu Jie Liu Bing Dai Xinzu Chen Fang Wang Fan Zeng Hong Xu Jiankun Hu Xianming Mo | 2012 | Cell Research2012，22，1： | 50 |
| 2 | Smart metasurface with self-adaptively reprogrammable functions显示文摘Intelligence at either the material or metamaterial level is a goal that researchers have been pursuing.From passive to active,metasurfaces have been developed to be programmable to dynamically and arbitrarily manipulate electromagnetic(EM)wavefields.However,the programmable metasurfaces require manual control to switch among different functionalities.Here,we put forth a smart metasurface that has self-adaptively reprogrammable functionalities without human participation.The smart metasurface is capable of sensing ambient environments by integrating an additional sensor(s)and can adaptively adjust its EM operational functionality through an unmanned sensing feedback system.As an illustrative example,we experimentally develop a motion-sensitive smart metasurface integrated with a three-axis gyroscope,which can adjust self-adaptively the EM radiation beams via different rotations of the metasurface.We develop an online feedback algorithm as the control software to make the smart metasurface achieve single-beam and multibeam steering and other dynamic reactions adaptively.The proposed metasurface is extendable to other physical sensors to detect the humidity,temperature,illuminating light,and so on.Our strategy will open up a new avenue for future unmanned devices that are consistent with the ambient environment. | Qian Ma Guo Dong Bai Hong Bo Jing Cheng Yang Lianlin Li Tie Jun Cui | 2019 | Light(Science & Applications)2019，8，1： | 13 |
| 3 | Evolution of secondary phase particles during deformation of Al-5Ti-1B master alloy and their effect on α-Al grain refinement显示文摘Addition of Al-5Ti-1B alloy to molten aluminum alloys can refine α-Al grains effectively and thereby improve their strength and toughness. TiAl_3 and TiB_2 in Al-5Ti-1B alloy are the main secondary-phase particles for refinement, while the understanding on the effect of their sizes on α-Al grain refinement continues to be fragmented. Therefore, Al-5Ti-1B alloys with various sizes and morphologies of the secondary-phase particles were prepared by equal channel angular pressing(ECAP). Evolution of the secondary-phase particles during ECAP process and their impact on α-Al grain refinement were studied by X-ray diffraction and scanning electron microscope(SEM). Results show that during the ECAP process, micro-cracks firstly appeared inside TiAl_3 particles and then gradually expanded, which resulted in continuous refinement of TiAl_3 particles. In addition, micro-distribution uniformity of TiB_2 particles was improved due to the impingement of TiAl_3 particles to TiB_2 clusters during deformation. Excessively large sizes of TiAl_3 particles would reduce the number of effective heterogeneous nucleus and thus resulted in poor grain refinement effectiveness. Moreover, excessively small TiAl_3 particles would reduce inhibitory factors for grain growth Q and weaken grain refinement effectiveness. Therefore, an optimal size range of 18-22 μm for TiAl_3 particles was suggested. | Hong Yu Ning Wang Renguo Guan Di Tie Zheng Li Yanan An Yang Zhang | 2018 | Journal of Materials Science & Technology2018，34，12： | 6 |
| 4 | Purification and Characterization of a Novel Tetradecapeptide from Ginseng Polypeptides with Enhancing Memory Activity for Mice显示文摘 | LUO Hao-ming JIANG Rui-zhi YANG Xiao-hong CHEN Ying-hong HONG Tie WANG Ying | 2013 | Chemical Research in Chinese Universities2013，29，4： | 6 |
| 5 | Large-area high quality PtSe2 thin film with versatile polarity显示文摘Two-dimensional(2D)materials have attracted increasing attention for their outstanding structural and electrical properties.However,for mass-production of field effect transistors(FETs)and potential applications in integrated circuits,large-area and uniform 2D thin films with high mobility,large on-off ratio,and desired polarity are needed to synthesize firstly.Here,a transfer-free growth method for platinum diselenide(PtSe2)films has been developed.The PtSe2 films have been synthesized with various thicknesses in centimeter-sized scale.Typical FET made from a few layer PtSe2 show p-type unipolar,with a high field-effect hole mobility of 6.2 cm^(2) V^(−1) s^(−1) and an on-off ratio of 5×10^(3).The versatile semimetal-unipolar-ambipolar transition in synthesized PtSe2 films is also firstly observed as the thickness thinning.This work realizes the large-scale preparation of PtSe2 with prominent electrical properties and provides a new strategy for polarity's modulation. | Wei Jiang Xudong Wang Yan Chen Guangjian Wu Kun Ba Ningning Xuan Yangye Sun Peng Gong Jingxian Bao Hong Shen Tie Lin Xiangjian Meng Jianlu Wang Zhengzong Sun | 2019 | InfoMat2019，1，2： | 5 |
| 6 | A pure blue light emitting binaphthyl derivative:Synthesis and properties显示文摘有 3 和 3 个′位置上的分核的联萘衍生物被综合并且经由铃木描绘了偶合反应。在答案最大的排放被作为参考拿 9,10-diphenyl 蒽与 68% 的量子效率在 390 nm 定位,当它与从聚集状态导致固态膜的 104 nm 的 FWHM 被转移到 450 nm 时。玻璃化转变温度(Tg ) 和分解温度被测量分别地,由 DSC 和 TGA 是 184 和 447 ° C。不同于它的光致发光光谱,电镀物品发光光谱在大约 460 nm 和表演达到顶点相应于纯蓝排出物的 69 nm 的 FWHM。刺激电压,发光性和效率最大值是有并列的 CIE 颜色的 5 V, 2953 cd/m2 和 1.37 cd/A (0.16, 0.15 ) ,在 ITO/NPB (40 nm ) 的设备结构 /PY-BN-PY (15 nm )/BPhen (40 nm )/Mg :47 号元素银的化学符号。 | Qing Guo He Zeng Ze Chu Gang Tie Lei An Jun Qin Hong Zhen Lin Feng Lian Bai Jian Gong Cheng Yong Qiu | 2008 | Chinese Chemical Letters2008，19，4： | 4 |
| 7 | Dual-polarization programmable metasurface modulator for near-field information encoding and transmission显示文摘Controlling the polarization state of electromagnetic waves is an important topic in microwaves due to the enormous application potential in radar technology and mobile communications. Here, we propose a programmable metasurface based on single-pole double-throw switches to realize multifunctional polarization conversions.A structure of the double-sided metallic pattern is adopted in the metasurface, in which a novel double-pole double-throw hub is achieved to guide the energy direction. Such a mechanism successfully induces multiple transmission channels into the metasurface structure for functional design. By controlling the states of the switches with a field programmable gate array, the x-and y-polarizations of the incident waves can be efficiently modulated into linear co-and cross-polarizations of transmitted waves, suggesting a higher degree of freedom on wave manipulations. The proposed metasurface can be developed as a near-field information encoder to transmit binary coding sequence according to the energy distribution. Character transmissions are realized by programming binary ASCII codes on the transmitted fields. Nine supercells on the metasurface can encode 9-bit binary information in one frame of near-field imaging, which can be switched in real time with high speed. We envision that this work will develop digital coding applications to control the polarization information. | LEI CHEN QIAN MA QIAN FAN NIE QIAO RU HONG HAO YANG CUI YING RUAN TIE JUN CUI | 2021 | Photonics Research2021，9，2： | 4 |
| 8 | A versatile photodetector assisted by photovoltaic and bolometric effects显示文摘The advent of low-dimensional materials with peculiar structure and superb band properties provides a new canonical form for the development of photodetectors.However,the limited exploitation of basic properties makes it difficult for devices to stand out.Here,we demonstrate a hybrid heterostructure with ultrathin vanadium dioxide film and molybdenum ditelluride nanoflake.Vanadium dioxide is a classical semiconductor with a narrow bandgap,a high temperature coefficient of resistance,and phase transformation.Molybdenum ditelluride,a typical two-dimensional material,is often used to construct optoelectronic devices.The heterostructure can realize three different functional modes:(i)the p-n junction exhibits ultrasensitive detection(450 nm-2μm)with a dark current down to 0.2 pA and a response time of 17μs,(ii)the Schottky junction works stably under extreme conditions such as a high temperature of 400 K,and(iii)the bolometer shows ultrabroad spectrum detection exceeding 10μm.The flexible switching between the three modes makes the heterostructure a potential candidate for next-generation photodetectors from visible to longwave infrared radiation(LWIR).This type of photodetector combines versatile detection modes,shedding light on the hybrid application of novel and traditional materials,and is a prototype of advanced optoelectronic devices. | Wei Jiang Tan Zheng Binmin Wu Hanxue Jiao Xudong Wang Yan Chen Xiaoyu Zhang Meng Peng Hailu Wang Tie Lin Hong Shen Jun Ge Weida Hu Xiaofeng Xu Xiangjian Meng Junhao Chu Jianlu Wang | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 9 | The Genomic Characterization of Enterovirus D68 from 2011 to 2015 in Beijing, China显示文摘enterovirus D68 上的回顾的监视研究在中国北京被执行,跟随最大、很普遍的 EV-D68 感染,它发生在 USA。从 2011 年 1 月到 2015 年 7 月, EV-D68 在中国北京与呼吸感染在 12 个个人被识别。种系发生的关系基于 genomic 顺序排列证明有二个系,从 2011 ~ 2015 在北京传播。属于的八 EV-D68 紧张组织 1 和四属于组 3。从在 2014 的北京的所有 EV-D68 紧张独立被聚类进组 1 的亚群 II。把结果基于这些,我们断定北京 EV-D68 紧张有小协会, EV-D68 紧张在 2014 美国爆发传播。 | ZHANG Tie Gang LI Hong Quan LI Ai Hua CHEN Meng GONG Cheng LUO Ming DONG Mei HUANG Fang | 2016 | Biomedical and Environmental Sciences2016，29，9： | 2 |
| 10 | Progress in Silicon Nanowire-Based Field-Effect Transistor Biosensors for Label-Free Detection of DNA显示文摘作为一个维的半导体的 nanomaterial,硅 nanowire (SiNW ) 被合并了到文件效果晶体管(联邦货物税) 在察觉到应用的 DNA 增加功效和 signal-to-noise 的设备。由于高敏感,优秀选择,没有标签的察觉,直接电的读出,和小型化的优点, SiNW 基于联邦货物税的 DNA 传感器在分子的诊断,定序的 DNA,基因表达式,和药发现的应用程序被认为是一个重要工具。这里,我们为没有标签的电的 DNA 察觉在 SiNW 联邦货物税传感器中考察最近的进步。我们首先介绍 SiNW 联邦货物税 DNA 传感器, SiNW 制造技术, nanowire 表面上的 bio-functionalization,和设备敏感的改进的工作原则。然后,我们在 DNA 杂交,传染病毒, microRNA,基因变化(DNA 变化, DNA methylation,和 DNA 修理) ,和 protein-DNA 相互作用的察觉总结 SiNW 传感器的应用。我们探讨包括察觉的敏感,选择,和限制察觉到性能的几个关键点。最后,这块地的观点,挑战,和一些答案也被讨论。 | Na Lu Anran Gao Hong Zhou Yi Wang Xun Yang Yuelin Wang Tie Li | 2016 | Chinese Journal of Chemistry2016，34，3： | 2 |
| 11 | Effects of Astragali root and Hedysari root on the murine B and T cell differentiation显示文摘 | Qing-Hua Song Takao Kobayashi Li-Mei Xiu Tie Hong Jong-Chol Cyong | 2000 | Journal of Ethnopharmacology2000，，1： | 2 |
| 12 | ALDH2 is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural chinese sample显示文摘 | Ellen E. Quillen Xiang‐Ding Chen Laura Almasy Fang Yang Hao He Xi Li Xu‐Yi Wang Tie‐Qiao Liu Wei Hao Hong‐Wen Deng Henry R. Kranzler Joel Gelernter | 2014 | Genet2014，，2： | 2 |
| 13 | Hepato-protective Effect of Polysaccharides Extracted from Inula Britannica Flower for Mice显示文摘The polysaccharides extracted from Inula britannica flower(IBP) exhibited a significant anti-liver injury activity.The properties and chemical compositions of IBP were analyzed via high performance liquid chromatography(HPLC) and infrared spectroscopy(IR) methods.The results show that the molecular weight distribution of IBP is from 600 to 3500.The weight-average molecular weight is 1099.IBP consists of mannose,glucuronic acid,rhamnose,galacturonic acid,glucose,galactose and arabinose with a molar ratio of 4.1:1:1.4:2.7:14.6:6.3:7.9.The IR spectrum of IBP reveals the typical characteristics of polysaccharides and proteins.After administration of IBP with 100,50 and 25 mg/kg body mass to liver injury mice induced by CCl 4 or bacillus calmette guerin-lipopolysaccharide(BCG-LPS),not only the blood alanine aminotransferase(ALT) and aspartate aminotransferase(AST) levels decreased significantly(P<0.05),but aslo the liver tissue malondialdehyde(MDA) level decreased significantly(P<0.01).The superoxide dismutase(SOD) level increased significantly(P<0.01).IBP shows significant anti-liver injury and antioxidation activity. | HONG Tie DONG Man GAO Yan ZHAO Jing WU Yi | 2012 | Chemical Research in Chinese Universities2012，28，6： | 2 |
| 14 | High-performance sub-10-nm monolayer black phosphorene tunneling transistors显示文摘 | Hong Li Jun Tie Jingzhen Li Meng Ye Han Zhang Xiuying Zhang Yuanyuan Pan Yangyang Wang Ruge Quhe Feng Pan Jing Lu | 2018 | Nano Research2018，11，5： | 2 |
| 15 | MEB-YOLO: An Efficient Vehicle Detection Method in Complex Traffic Road Scenes显示文摘Rapid and precise vehicle recognition and classification are essential for intelligent transportation systems,and road target detection is one of the most difficult tasks in the field of computer vision.The challenge in real-time road target detection is the ability to properly pinpoint relatively small vehicles in complicated environments.However,because road targets are prone to complicated backgrounds and sparse features,it is challenging to detect and identify vehicle kinds fast and reliably.We suggest a new vehicle detection model called MEB-YOLO,which combines Mosaic and MixUp data augmentation,Efficient Channel Attention(ECA)attention mechanism,Bidirectional Feature Pyramid Network(BiFPN)with You Only Look Once(YOLO)model,to overcome this problem.Four sections make up this model:Input,Backbone,Neck,and Prediction.First,to improve the detection dataset and strengthen the network,MixUp and Mosaic data improvement are used during the picture processing step.Second,an attention mechanism is introduced to the backbone network,which is Cross Stage Par-tial Darknet(CSPDarknet),to reduce the influence of irrelevant features in images.Third,to achieve more sophisticated feature fusion without increasing computing cost,the BiFPN structure is utilized to build the Neck network of the model.The final prediction results are then obtained using Decoupled Head.Experiments demonstrate that the proposed model outperforms several already available detection methods and delivers good detection results on the University at Albany DEtection and TRACking(UA-DETRAC)public dataset.It also enables effective vehicle detection on real traffic monitoring data.As a result,this technique is efficient for detecting road targets. | Yingkun Song Shunhe Hong Chentao Hu Pingan He Lingbing Tao Zhixin Tie Chengfu Ding | 2023 | Computers, Materials & Continua2023，，6： | 2 |
| 16 | Contamination of persistent organic pollutant(POPs) and relevant management in China显示文摘 | TIE W YONG L HONG Z | 2005 | Environment International2005，31，6： | 1 |
| 17 | A novel method to monitor the expression of microRNAs显示文摘 | Han-Jiang Fu Jie Zhu Ming Yang Zhuo-Yuan Zhang Yi Tie Hong Jiang Zhi-Xian Sun Xiao-Fei Zheng | 2006 | Molecular Biotechnology2006，，3： | 1 |
| 18 | Identification of human fetal liver miRNAs by a novel method显示文摘 | Hanjiang Fu Yi Tie Chengwang Xu Zhuoyuan Zhang Jie Zhu Yingxu Shi Hong Jiang Zhixian Sun Xiaofei Zheng | 2005 | FEBS Letters2005，，17： | 1 |
| 19 | Hybrid intelligent modeling approach for online predicting and simulating surface temperature of HVs显示文摘Online prediction as well as online simulation of surface temperature will play a sig-nificant role in flight safety of future near space hypersonic vehicles(HVs).But it still remains a classical scientific problem both in thermodynamics and aerospace sci-ence.In view of the complex HV structure and complex heat conduction procedure,three-dimensional numerical simulation is too inefficient for online prediction,while cur-rent rapid computation methods cannot meet the requirement of accuracy.Therefore,a hybrid intelligent dynamic modeling approach is proposed to estimate the surface temperature of HV with the combination of mechanism equations,test data and intel-ligent modeling technology.A simplified model based on a mechanism equation and experimental formulas is presented for predicting or simulating transient heat conduc-tion procedure efficiently,while a case-based reasoning(CBR)algorithm is developed to estimate two uncertain coefficients in the simplified model.Furthermore,a support vector regression(SVR)-based model is developed to compensate the modeling error.With the data both from high-precision finite element computation and from real-world HV thermal protection experiments,a number of comparative simulations demonstrate the effectiveness of the proposed hybrid intelligent modeling approach. | Ming Tie Hong Fang Jianlin Wang Weihua Chen | 2022 | International Journal of Modeling, Simulation, and Scientific Computing2022，13，2： | 1 |
| 20 | Fine mapping of a recessive genic male sterility gene (Bnms3) in rapeseed (Brassica hapus) with AFLP and Arabidopsis-derived PCR markers显示文摘 | tiE J P KE L P HONG D F | 2008 | Theor Appl Genet2008，117，： | 1 |
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