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| 1 | Molecular dynamics study on the relationships of modeling,structural and energy properties with sensitivity for RDX-based PBXs显示文摘In this paper,a primary model is established for MD(molecular dynamics) simulation for the PBXs(polymer-bonded explosives) with RDX(cyclotrimethylene trinitramine) as base explosive and PS as polymer binder.A series of results from the MD simulation are compared between two PBX models,which are represented by PBX1 and PBX2,respectively,including one PS molecular chain having 46 repeating units and two PS molecular chains with each having 23 repeating units.It has been found that their structural,interaction energy and mechanical properties are basically consistent between the two models.A systematic MD study for the PBX2 is performed under NPT conditions at five different temperatures,i.e.,195 K,245 K,295 K,345 K,and 395 K.We have found that with the temperature increase,the maximum bond length(L max) of RDX N N trigger bond increases,and the interaction energy(E N-N) between two N atoms of the N-N trigger bond and the cohesive energy density(CED) decrease.These phenomena agree with the experimental fact that the PBX becomes more sensitive as the temperature increases.Therefore,we propose to use the maximum bond length L max of the trigger bond of the easily decomposed and exploded component and the interaction energy E N-N of the two relevant atoms as theoretical criteria to judge or predict the relative degree of heat and impact sensitivity for the energetic composites such as PBXs and solid propellants. | XIAO JiJun ZHAO Li ZHU Wei CHEN Jun JI GuangFu ZHAO Feng WU Qiang XIAO HeMing | 2012 | Science China Chemistry2012，55，12： | 12 |
| 2 | Fiber Bragg grating monitors for thermal and stress of the composite insulators in transmission lines显示文摘Running composite insulators are prone to failure due to their harsh surrounding work environment, which directly affects the safe operation of transmission lines. This paper puts forward the method of using fiber Bragg grating(FBG) as the monitors to parameters correlated with thermal and stress of the composite insulators in transmission lines at working status. Firstly, monitoring points are found out by the mechanical test on composite insulator samples. Secondly, based on the monitoring theory, this paper introduces the feasibility design frame of the composite insulator with FBG implanted in the rod and the online monitor system. At last, it describes applications of this monitor system in the field of transmission lines. | Heming Deng Wei Cai You Song Jinsong Liu Christopher Redman Qiandong Zhuang | 2018 | Global Energy Interconnection2018，1，3： | 6 |
| 3 | Molecular dynamics simulations of AP/HMX composite with a modified force field显示文摘 | Wei Zhu Xijun Wang Jijun Xiao Weihua Zhu Huai Sun Heming Xiao | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 4 | Cavitation Erosion Behavior of CrMnN Duplex Stainless Steel in Distilled Water and 3% NaCl Solution显示文摘The cavitation erosion (CE) behavior of CrMnN ferrite-austenite duplex stainless steel in distilled water and 3% NaCl solution was investigated by using a magnetostrictive-induced CE facility. The damaged surfaces were observed by scanning electron microscope (SEM). It was found that the CE resistance of CrMnN steel was higher than that of 0Cr13Ni5Mo steel. The mass loss rate of CrMnN steel in distilled water was similar to that in 3% NaCl except at the early stage of CE. The failure mode of ferrite phase was brittle fracture, which had adverse effect on the resistance to CE, while the failure of austenite phase was a ductile failure in CrMnN steel. The excellent resistance to CE was related to the good mechanical properties of austenitic phase and the consumption of CE energy by plastic deformation involving slip and twinning. | Suzhen LUO, Yugui ZHENG, Wei LIU, Heming JING, Zhiming YAO and Wei KEState Key Laboratory for Corrosion and Protection, Institute of Metai Research, Chinese Academy of Sciences, Shenyang 110016, China | 2003 | Journal of Materials Science & Technology2003，19，4： | 1 |
| 5 | Research on the Production Efficiency andUtilizing Rate of Potassium Fertilizer for Rape in Yunnan Province 显示文摘 | Minglian FU Genze U Xiaoyan YUAN Derong CHENG Xuan ZHU Shengguang WEI Hongyan LJ Shi PENG Yuankuan LEI Bin HE Heming WEN Shaowei YU | 2011 | Agricultural Science & Technology2011，12，14： | 1 |
| 6 | Relationship between estrogen receptor gene polymorphism and clinical indexes associated with coronary heart disease显示文摘Objective: To investigate the relationship between estrogen receptor(ER) gene and the clinical indexes associated with coronary heart disease (CHD). Methods: By means of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), we analyzed ER gene polymorphism in 84 CHD patients and 61 healthy subjects and non-CHD inpatients. The clinical indexes associated with CHD were analyzed in relation to the three ER genotypes. Results: There were significant differences in the incidence of hypertension (58.62%), fibrinogen (Fib) concentration (3.5±0.8 g/L), body mass index (BMI, 25.1±3.2), HDL-C concentration (1.0±0.2 mmol/L) between PP genotype group and other genotype groups (P<0.05). Conclusion: ER gene polymorphism may affect ER-mediated cardiovascular protective effect by modulating the expression of ER. | 吴赛珠 李曦 郑华 郭志刚 赖文岩 吴迎星 Wei Heming | 2003 | Journal of Medical Colleges of PLA(China)2003，18，4： | 1 |
| 7 | Online measurement of equivalent salt deposit density by using optical technology显示文摘 | CAI Wei DENG Heming ZHOU Guohua | 2013 | IEEE Trans on Dielectrics and Electrical Insulation2013，20，2： | 1 |
| 8 | Erosion–corrosion of various oil-refining materials in naphthenic acid显示文摘 | Xinqiang Wu Heming Jing Yugui Zheng Zhiming Yao Wei Ke | 2003 | Wear2003，，1： | 1 |
| 9 | Direct laser writing spiral Sagnac waveguide for ultrahigh magnetic field sensing显示文摘A high-birefringence spiral Sagnac waveguide(SSW)device fabricated via direct laser writing(DLW)using a two-photon polymerization(2PP)technique is proposed,designed,and experimentally demonstrated as an ultrahigh magnetic field sensor.The sensor comprises a Y-style tapered waveguide and an SSW containing two microfluidic channels.The SSW has a total length of∼2.4 mm and a spiral radius of∼200μm.Due to the asymmetric structure,the SSW has a high birefringence of 0.016,which can be designed as a magnetic field sensor,as a magnetic fluid can be filled into the microfluidic channel changing the guiding mode and the birefringence and consequently leading to a change in phase of the interferometer when the applied magnetic field changes.The experimental results show that the proposed photonic device has a sensitivity to magnetic fields as high as 0.48 nm/Oe within a range from 10 to 100 Oe.The proposed device is very stable and easy to fabricate,and it can therefore be used for weak magnetic field detection. | Dengwei Zhang Zhihang Zhang Heming Wei Jianrong Qiu Sridhar Krishnaswamy | 2021 | Photonics Research2021，9，10： | 0 |
| 10 | 小鼠心房肌细胞分离和电生理功能鉴定显示文摘目的建立小鼠心房肌细胞分离技术,评价心房肌细胞的质量和电生理特性。方法通过改良Bustamante等人所建立的分离人心房肌细胞的方法,分离成年小鼠单个心房肌细胞。台盼蓝染色判定心房肌细胞活性。全细胞膜片钳技术记录细胞膜钾电流,证实细胞的电生理特性。结果分离出的小鼠心房肌细胞呈梭状、横纹清晰、两端边缘锐利、遮光性较强、细胞无明显搏动。全细胞膜片钳记录细胞膜钾电流(Ito,Ikur,Ik1),证实所分离的心房肌细胞具有典型的钾电流特征。结论 Bustamante法经改良后可以成功地获得适合做电生理需要的单个小鼠心房肌细胞,且易于操作,重现性好。 | 邱素华 WEI Heming 李康琪 张广钦 | 2011 | 中国现代药物应用2011，5，4： | 0 |
| 11 | Two-photon 3D printed spring-based Fabry-Pérot cavity resonator for acoustic wave detection and imaging显示文摘Optical fiber microresonators have attracted considerable interest for acoustic detection because of their compact size and high optical quality.Here,we have proposed,designed,and fabricated a spring-based Fabry-Pérot cavity microresonator for highly sensitive acoustic detection.We observed two resonator vibration modes:one relating to the spring vibration state and the other determined by the point-clamped circular plate vibration mode.We found that the vibration modes can be coupled and optimized by changing the structure size.The proposed resonator is directly 3D printed on an optical fiber tip through two-photon polymerization and is used for acoustic detection and imaging.The experiments show that the device exhibits a high sensitivity and low noise equivalent acoustic signal level of 2.39 mPa∕Hz^(1∕2)at 75 kHz that can detect weak acoustic waves,which can be used for underwater object imaging.The results demonstrate that the proposed work has great potential in acoustic detection and biomedical imaging applications. | HEMING WEI ZHANGLI WU KEXUAN SUN HAIYAN ZHANG CHEN WANG KEMIN WANG TIAN YANG FUFEI PANG XIAOBEI ZHANG TINGYUN WANG SRIDHAR KRISHNASWAMY | 2023 | Photonics Research2023，11，5： | 0 |
| 12 | Changes in Sleep Duration and the Risk of Cognitive Impairment Among Older Adults Aged 65 Years and Over—China,2014–2019显示文摘Summary What is already known about this topic?Earlier studies indicated that shorter or excessive sleep duration at baseline was related to cognitive impairment.Yet few studies have been concerned with the association between sleep duration changes and cognitive performance,especially in low-and middleincome countries.What is added by this report?A prospective cohort study suggests that maintaining moderate sleep duration may lead to optimal cognitive performance.Either decreasing,increasing,or keeping a longer sleep duration is associated with the risk of cognitive impairment among Chinese elderly aged 65 years and over. | Yue Wei Heming Pei Jinlong Lin Xiaojin Yan Gong Chen | 2022 | China CDC weekly2022，4，42： | 0 |
| 13 | 微矩阵电极在人类多功能干细胞分化的心肌细胞上的应用显示文摘目的应用微矩阵电极系统MEA(Multielectrode Array,MEA)鉴别人类多功能干细胞分化的心肌细胞的电生理特性并建立体外药物检测平台。方法将人类多功能干细胞分化的心肌细胞团贴于经0.1%明胶处理过的MEA芯片,培养3d后,心肌细胞团保持节律性收缩,应用McRack采集分析软件记录给予10M河豚毒素(TTX)前后心肌细胞场电位(field potential duration,FPD)和心率(heart rate)的变化。结果该方法可用于记录心肌细胞胞外电生理特性;10M的TTX可降低心率,缩短FP min的幅度。结论该技术操作简单,高效,可成功记录人类多功能干细胞分化的心肌细胞的电生理特性,并可用于临床药物筛选。 | 卢珺 Heming Wei 张广钦 | 2012 | 中国现代药物应用2012，6，5： | 0 |
| 14 | Effect of chemical metallurgical factors on contents of S and P in weld metal during SAW显示文摘EffectofchemicalmetallurgicalfactorsoncontentsofSandPinweldmetalduringSAWXUESongbai;YEDonglin;HAOHemingandLIUWei(HarbinResear... | XUE Songbai YE Donglin HAO Heming and LIU Wei(sineior engineer,Harbin Research Institute of Welding. Harbin. 150080.) | 1996 | China Welding1996，5，1： | 0 |
| 15 | Advanced nano drug delivery systems for neuroprotection against ischemic stroke显示文摘Ischemic stroke(IS)represents a significant threat to brain health due to its elevated mortality and disability rates.The efficacy of small-molecule neuroprotective agents has been impeded by challenges associated with traversing the blood-brain barrier(BBB)and limited bioavailability.Conversely,advanced nano drug delivery systems hold promise for overcoming these obstacles by facilitating efficient transportation across the BBB and maintaining optimal drug concentrations.This review aims to explore advanced neuroprotective nano drug delivery systems as a means of effectively administering neuroprotective agents to the brain using pharmaceutical approaches in the treatment of IS.By examining these systems,researchers and clinicians can gain valuable insights and innovative concepts,illuminating the potential of advanced neuroprotective nano drug delivery systems.Leveraging these advancements can drive the progress of pioneering and efficacious therapeutic interventions for IS. | Chenchen Xie Jun Liao Ning Zhang Yuhan Sun Yi Li Liyan Xiong Yingnan Zhang Xiaoyan Liu Wei Su Heming Chen Ping Zeng Xiaoqing Zhang Ying Lu Tingfang Wang Chuan Zhang | 2024 | Chinese Chemical Letters2024，35，2： | 0 |
| 16 | Research advances in peptide-drug conjugates显示文摘Peptide-drug conjugates(PDCs)are drug delivery systems consisting of a drug covalently coupled to a multifunctional peptide via a cleavable linker.As an emerging prodrug strategy,PDCs not only preserve the function and bioactivity of the peptides but also release the drugs responsively with the cleavable property of the linkers.Given the ability to significantly improve the circulation stability and targeting of drugs in vivo and reduce the toxic side effects of drugs,PDCs have already been extensively applied in drug delivery.Herein,we review the types and mechanisms of peptides,linkers and drugs used to construct PDCs,and summarize the clinical applications and challenges of PDC drugs. | Liming Gong Heming Zhao Yanhong Liu Hao Wu Chao Liu Shuangyan Chang Liqing Chen Mingji Jin Qiming Wang Zhonggao Gao Wei Huang | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 0 |
| 17 | Phenomena and Mechanism of Positive Pulsed Discharge Branching in Two-phase Mixtures显示文摘Discharge branching is a general phenomenon in atmospheric-pressure air,dense gases,and two-phase mixtures(TPMs).In this work,an ultraviolet imaging device is utilized to investigate the branching of positive pulsed discharges in TPMs.Comparison among the captured images indicates that the branching is caused by the voltages and the macropartilces in the discharge channels combining together.The interaction of macroparticles with ions,electrons or photons is one reason for the branching behavior of pulsed discharges.The generation of electrons at the discharge front closely relates to the work function of dielectric macroparticles,which is a key parameter influencing the electron-emission ability of macroparticle surfaces.The electric field alteration under various applied voltage in TPMs,which is calculated by a two-dimension finite element method,is the other reason for the guiding effect of macroparticles on the streamers compared with in the air. | DENG Heming ZHANG Guangzhou XU Yuhang HE Zhenghao ZHU Hongzhao LIANG Wei | 2013 | 高电压技术2013，39，9： | 0 |
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