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| 1 | Achieving maximum power transfer of inductively coupled wireless power transfer system based on dynamic tuning control显示文摘As an emerging research field,inductively coupled wireless power transfer(ICWPT) technology has attracted wide spread attention recently.In this paper,the maximum power transfer performances of four basic topologies labeled as SS,SP,PS and PP are investigated.By modeling the equivalent circuits of these topologies in high frequency(HF),the primary resonance compensation capacitances for maximum power transfer capability are deduced.It is found that these capacitances fluctuate with load resistance change,which is disadvantageous to SP,PS and PP topologies and an obstacle to their practical applications as well.To solve this problem,a phase controlled inductor circuit is proposed.By adjusting the triggering angle,the real-time dynamic tuning control can be achieved to guarantee maximum power transfer.Finally,simulations and experiments show that the proposed method is of great effectiveness and reliability to solve the issue of resonance compensation capacitance fluctuation with load change and to guarantee the flexible applications of all topologies. | QIANG Hao HUANG XueLiang TAN LinLin JI QingJing ZHAO JiaMing | 2012 | Science China(Technological Sciences)2012，55，7： | 23 |
| 2 | Ferroptosis as a novel form of regulated cell death:Implications in the pathogenesis,oncometabolism and treatment of human cancer显示文摘The treatment of cancer mainly involves surgical excision supplemented by radiotherapy and chemotherapy.Chemotherapy drugs act by interfering with tumor growth and inducing the death of cancer cells.Anti-tumor drugs were developed to induce apoptosis,but some patient’s show apoptosis escape and chemotherapy resistance.Therefore,other forms of cell death that can overcome the resistance of tumor cells are important in the context of cancer treatment.Ferroptosis is a newly discovered iron-dependent,non-apoptotic type of cell death that is highly negatively correlated with cancer development.Ferroptosis is mainly caused by the abnormal increase in iron-dependent lipid reactive oxygen species and the imbalance of redox homeostasis.This review summarizes the progression and regulatory mechanism of ferroptosis in cancer and discusses its possible clinical applications in cancer diagnosis and treatment. | Feifei Pu Fengxia Chen Zhicai Zhang Deyao Shi Binlong Zhong Xiao Lv Andrew Blake Tucker Jiaming Fan Alexander J.Li Kevin Qin Daniel Hu Connie Chen Hao Wang Fang He Na Ni Linjuan Huang Qing Liu William Wagstaff Hue H.Luu Rex C.Haydon Le Shen Tong-Chuan He Jianxiang Liu Zengwu Shao | 2022 | Genes & Diseases2022，9，2： | 6 |
| 3 | Incidence and clinical characteristics of inflammatory bowel disease in a developed region of G uangdong P rovince, C hina: A prospective population‐based study显示文摘 | Zhirong Zeng Zhenhua Zhu Yuyu Yang Weishan Ruan Xiabiao Peng Yuhuan Su Lin Peng Jinquan Chen Quan Yin Chao Zhao Haihua Zhou Shuai Yuan Yuantao Hao Jiaming Qian Siew Chien Ng Minhu Chen Pinjin Hu | 2013 | J Gastroenterol Hepatol2013，，7： | 5 |
| 4 | Dynamically reconfigurable subwavelength optical device for hydrogen sulfide gas sensing显示文摘The importance of tunable subwavelength optical devices in modern electromagnetic and photonic systems is indisputable.Herein,a lithography-free,wide-angle,and reconfigurable subwavelength optical device with high tunability operating in the near-infrared regions is proposed and experimentally demonstrated,based on a reversible nanochemistry approach.The reconfigurable subwavelength optical device basically comprises an ultrathin copper oxide(CuO)thin film on an optical thick gold substrate by utilizing the reversible chemical conversion of CuO to sulfides upon exposure to hydrogen sulfide gas.Proof-of-concept experimental results show that the maximal modulation depth of reflectance can be as high as 90%at the wavelength of 1.79μm with the initial thickness of CuO taken as 150 nm.Partially reflected wave calculations combined with the transfer matrix method are employed to analytically investigate the optical properties of the structure,which show good agreement with experimental results.We believe that the proposed versatile approaches can be implemented for dynamic control management,allowing applications in tunable photonics,active displays,optical encryption,and gas sensing. | ZHENGJI WEN JIALIANG LU WEIWEI YU HAO WU HAO XIE XIAOHANG PAN QIANQIAN XU ZIJI ZHOU CHONG TAN DONGJIE ZHOU CHANG LIU YAN SUN NING DAI JIAMING HAO | 2021 | Photonics Research2021，9，10： | 1 |
| 5 | ITO/Cu multilayer electrodes for high-brightness electrochromic displays显示文摘Fabry-Perot(F-P)nanocavity-type electrochromic devices with multicolor tunability have attracted significant interest in the past two years for their potential uses in a wide variety of applications,such as electronic display,military camouflage,and dynamic decoration.However,challenges such as insufficient brightness,lengthy switching times,and poor cycling stability have yet to be overcome.Herein,we demonstrate electrochromic electrodes based on ITO/Cu as both the current collector and the reflective layer,with WO_(3 )as the electrochromic material,forming a unique three-layered structure.The constituted WO_(3 )/ITO/Cu films present a high brightness value of about 84%before coloration,and a decent brightness value of 48%after coloration at−0.8V.Moreover,a fast switching time between different coloration states(tc=2.2s;tb=1s)is recorded,attributed to the extremely low sheet resistivity of the ITO/Cu current collector.The films also reveal excellent electrochemical cycling stability across 2000 cycles. | Xueqing Tang Zishou Hu Zhen Wang Jian Chen Xinyang Mu Ge Song Peiyan Sun Zhengji Wen Jiaming Hao Shan Cong Zhigang Zhao | 2022 | eScience2022，2，6： | 1 |
| 6 | Nearly Total Absorption of Light and Heat Generation by Plasmonic Metamaterials 显示文摘 | Hao Jiaming Zhou Lei Qiu Min | 2011 | Physical Review2011，83，16： | 1 |
| 7 | Manipulating electromagnetic wave polarizations by anisotropic metamaterials显示文摘 | Hao Jiaming Yuan Yu | 2007 | Phys Rev Lett2007，99，06： | 1 |
| 8 | Manipulating electromagnetic wave polarizations by anisotropic metamaterials显示文摘 | HAO Jiaming YUAN Yu RAN Lixin | 2007 | Physical Review Letters2007，99，06： | 1 |
| 9 | Detection and Localization of Active Gastrointestinal Bleeding With Multidetector Row Computed Tomography Angiography: A Five-year Prospective Study in One Medical Center显示文摘 | Hao Sun Zhengyu Jin Xiaoguang Li Jiaming Qian Jianchun Yu Feng Zhu Huadong Zhu | 2012 | Journal of Clinical Gastroenterology2012，，1： | 1 |
| 10 | Manipulating Electromagnetic Wave Polarizations by Anisotropic Metamaterials显示文摘 | Hao Jiaming | 2007 | Phys Rev Lett2007，99，06： | 1 |
| 11 | Manipulating electromagnetic wave polarizations by anisotropic metamaterials显示文摘 | Hao Jiaming Yuan Yu Ran Lixin | | Physical Review Letters0，，： | 1 |
| 12 | High per-formance optical absorber based on a plasmonic metamate-rial 显示文摘 | Hao Jiaming Wang Jing Liu Xianliang | 2001 | Appl Phys Lett2001，96，25： | 1 |
| 13 | Micromotor-derived composites for biomedicine delivery and other related purposes显示文摘Biocompatible designed micromotor has attracted more and more concerns in the field of biomedicine due to their self-propulsion and delivery abilities.Such micromotors,mostly consisting of alkali earth metals,hydrogels,or other motile biomaterials,can effectively transform chemical energy into mechanical or kinetic energy to achieve the expected delivery of cargos to the sites of action.Except for conveying power,the modifiable surface and inner cavity of micromotors guarantee that their potential as versatile delivery systems for therapeutic agents.Here,this review generalizes the propelling mechanisms,composites,and shapes of micromotors.Besides,the application of micromotor-derived composites for biomedicine delivery and other versatile purposes are also discussed. | Xiang Xu Zhiyi Huo Jiaming Guo Hao Liu Xiaole Qi Zhenghong Wu | 2020 | Bio-Design and Manufacturing2020，3，2： | 1 |
| 14 | Manipulating electromagnetic wave polarizations by anisotropic metamaterials显示文摘 | Hao Jiaming Yuan Yu Ran Lixin | | 0，，06： | 1 |
| 15 | Development of Diapirs and Accumulation of Natural Gases in Yinggehai Basin显示文摘Overpressure developed throughout most of the Yinggehai basin. The burial depth to top overpressure varied from about 1 600 m to 4 500 m, with the shallowest top overpressure occurring in the depocenter. The main cause of the overpressure was disequilibrium compaction resulting from rapid sedimentation of fine grained sediments. The overpressure was strengthened by the retention of fluids including gases due to lack of faults before diapir development. The diapirism in the Yinggehai basin was a combined result of the strong overpressure and the tensile stress field caused by the right lateral slip of the boundary fault. The diapirism, a product of the movement of overpressured fluids and plastic shales, shaped the vertical conduits from source to traps that would be absent without overpressured fluid release. Natural gas accumulation in traps in the diapir structure zones was also intermittent, which can be inferred from the inter reservoir compositional heterogeneity, transient thermal effect of fluid flow and migration fractionation. | Gong Zaisheng China National Offshore Oil Corporation, Beijing 100029 Yang Jiaming Institute of Petroleum Exploration and Development, China National Offshore Oil Corporation, Gaobeidian 074010 Hu Jianwu Hao Fang Faculty of Earth Resources, | 2001 | Journal of China University of Geosciences2001，12，2： | 1 |
| 16 | Manipulating electromagnetic wave polarizations by anisotropic metamaterials显示文摘 | Jiaming Hao Yu Yuan Lixin Ran | 2007 | Physical Review Letters2007，99，06： | 1 |
| 17 | Bone morphogenetic protein 4 (BMP4) promotes hepatic glycogen accumulation and reduces glucose level in hepatocytes through mTORC2 signaling pathway显示文摘Liver is an important organ for regulating glucose and lipid metabolism.Recent studies have shown that bone morphogenetic proteins(BMPs)may play important roles in regu-lating glucose and lipid metabolism.Inour previous studies,we demonstrated that BMP4 signif-icantly inhibits hepatic steatosis and lowers serum triglycerides,playing a protective role against the progression of non-alcoholic fatty liver disease(NAFLD).However,the direct impact of BMP4 on hepatic glucose metabolism is poorly understood.Here,we investigated the regulatory roles of BMP4 in hepatic glucose metabolism.Through a comprehensive analysis of the 14 types of BMPs,we found that BMP4 was one of the most potent BMPs in promoting hepatic glycogen accumulation,reducing the level of glucose in hepatocytes and effecting the expression of genes related to glucose metabolism.Mechanistically,we demonstrated that BMP4 reduced the hepatic glucose lewels through the activation of mTORC2 signaling pathway in vitro and in wivo.Collectively,our findings strongly suggest that BMP4 may play an essential role in regulating hepatic glucose metabolism.This knowledge should aid us to understand the molecular pathogenesis of NAFLD,and may lead to the development of novel therapeutics by exploiting the inhibitory effects of BMPs on hepatic glucose and lipid metabolism. | Liqin An Qiong Shi Ying Zhu Hao Wang Qi Peng Jinghong Wu Yu Cheng Wei Zhang Yanyu Yi Zihao Bao Hui Zhang Yetao Luo Jiaming Fan | 2021 | Genes & Diseases2021，8，4： | 1 |
| 18 | Argonaute(AGO)proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells(MSCs)显示文摘As multipotent progenitor cells,mesenchymal stem cells(MSCs)can renew themselves and give rise to multiple lineages including osteoblastic,chondrogenic and adipogenic lineages.It’s previously shown that BMP9 is the most potent BMP and induces osteogenic and adipogenic differentiation of MSCs.However,the molecular mechanism through which BMP9 regulates MSC differentiation remains poorly understood.Emerging evidence indicates that noncoding RNAs,especially microRNAs,may play important roles in regulating MSC differentiation and bone formation.As highly conserved RNA binding proteins,Argonaute(AGO)proteins are essential components of the multi-protein RNA-induced silencing complexes(RISCs),which are critical for small RNA biogenesis.Here,we investigate possible roles of AGO proteins in BMP9-induced lineage-specific differentiation of MSCs.We first found that BMP9 upregulated the expression of Ago1,Ago2 and Ago3 in MSCs.By engineering multiplex siRNA vectors that express multiple siRNAs targeting individual Ago genes or all four Ago genes,we found that silencing individual Ago expression led to a decrease in BMP9-induced early osteogenic marker alkaline phosphatase(ALP)activity in MSCs.Furthermore,we demonstrated that simultaneously silencing all four Ago genes significantly diminished BMP9-induced osteogenic and adipogenic differentiation of MSCs and matrix mineralization,and ectopic bone formation.Collectively,our findings strongly indicate that AGO proteins and associated small RNA biogenesis pathway play an essential role in mediating BMP9-induced osteogenic differentiation of MSCs. | Yukun Mao Na Ni Linjuan Huang Jiaming Fan Hao Wang Fang He Qing Liu Deyao Shi Kai Fu Mikhail Pakvasa William Wagstaff Andrew Blake Tucker Connie Chen Russell R.Reid Rex C.Haydon Sherwin H.Ho Michael J.Lee Tong-Chuan He Jian Yang Le Shen Lin Cai Hue H.Luu | 2021 | Genes & Diseases2021，8，6： | 1 |
| 19 | Large-scale coherent Ising machine based on optoelectronic parametric oscillator显示文摘Ising machines based on analog systems have the potential to accelerate the solution of ubiquitous combinatorial optimization problems.Although some artificial spins to support large-scale Ising machines have been reported,e.g.,superconducting qubits in quantum annealers and short optical pulses in coherent Ising machines,the spin stability is fragile due to the ultra-low equivalent temperature or optical phase sensitivity.In this paper,we propose to use short microwave pulses generated from an optoelectronic parametric oscillator as the spins to implement a large-scale Ising machine with high stability.The proposed machine supports 25,600 spins and can operate continuously and stably for hours.Moreover,the proposed Ising machine is highly compatible with high-speed electronic devices for programmability,paving a low-cost,accurate,and easy-to-implement way toward solving real-world optimization problems. | Qizhuang Cen Hao Ding Tengfei Hao Shanhong Guan Zhiqiang Qin Jiaming Lyu Wei Li Ninghua Zhu Kun Xu Yitang Dai Ming Li | 2022 | Light(Science & Applications)2022，11，12： | 0 |
| 20 | SiRNA-mediated ankyrin-G silence modulates the expression of voltage-gated Na channels in murine hippocampal HT22 cells显示文摘Background:Voltage-gated sodium channels are the targets of many commonly used antiepileptic drugs.NaV1.6,encoded by Scn8a,increased in chronic mesial temporal epilepsy animal models and co-localized with Ankyrin-G,encoded by Ank3.We hypothesized that inhibition of Ank3 transcription by siRNA decrease the expression of NaV1.6.Results:We characterized expression of the target genes in hippocampal neuron HT22 cells by Real time-PCR.The melt peak in the resolution curve of Scn1a,Scn8a and Ank3 were all unique.Ank3 transcription was interfered and the relative Ank3 mRNA levels of the three interfered groups compared to GAPDH were 0.89±0.13,0.52±0.07 and 0.26±0.05 while that of the negative control group was 1.01±0.08(P<0.05).When Ank3 transcription was inhibited by siRNA,the relative mRNA levels of Scn8a decreased in the three groups(0.91±0.09,0.33±0.06 and 0.25±0.05),compared to the negative control group(1.10±0.09).Tested by Western blotting,protein levels of ankyrinG and Nav1.6 decreased after ank3-siRNA.Ankyrin-G in negative control group,group1,group2 and group1+2 were 0.813±0.051,0.744±0.041,0.477±0.055 and 0.351±0.190 respectively(P<0.01)while Nav1.6 were 0.934±0.036,0.867±0.078,0.498±0.070 and 0.586±0.180(P<0.01).The quantity analysis of immunofluorescence showed significant decrease of ankyrin-G and Nav1.6(Student’s test,P=0.046 and 0.016 respectively).Conclusion:We therefore concluded that in HT22 cells the expression of Nav1.6 was down-regulated by Ank3 RNA interference. | Guanzhong Ni Xiaoting Hao Xiaodong Cai Jiaming Qin Liemin Zhou Patrick Kwan Ziyi Chen | 2019 | Acta Epileptologica2019，1，1： | 0 |
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