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| 1 | 臭氧对墨西哥豆瓢虫取食和生长的影响显示文摘本文报道在美国农业研究中心用臭氧在室内熏蒸和田间开顶熏蒸植物,用此饲养墨西哥豆瓢虫的实验,以及熏蒸后植物体内某些化合物含量变化的测定。结果表明,墨西哥豆瓢虫(Epilachna varivestis Mulsant)喜食臭氧(O_3)污染的植物,幼虫取食O_3污染植物后蛹显著重于取食未受污染植物所形成的蛹。根据豆瓢虫食性和植物体内糖含量的测定,可以认为,低浓度O_3污染导致植物体内糖含量的增加,是促使豆瓢虫取食量和蛹重增加的重要因素。 | 吴亚 Edward H.Lee Edward M.Barrows | 1990 | 昆虫学报1990，33，2： | 9 |
| 2 | 二氧化硫对墨西哥豆瓢虫的影响显示文摘空气污染对害虫的影响,国内尚无研究报道。本文报道了作者在美国农业研究中心植物胁迫实验室进行的部分工作。实验结果表明,在0.30ppmSO_2的作用下,墨西哥豆瓢虫(Epilachna varivestis)的取食量和蛹重增加;与未受污染的寄主植物相比,豆瓢虫偏食受污染的植物;而且有嗜食含较高糖分寄主植物的倾向;在污染空气中长成的成虫可消耗更多的植物物质。 | 吴亚 Edward H.Lee Edward M. Barrows | 1989 | 生态学报1989，9，4： | 9 |
| 3 | The recent advances in scaffolds for integrated periodontal regeneration显示文摘The periodontium is an integrated,functional unit of multiple tissues surrounding and supporting the tooth,including but not limited to cementum(CM),periodontal ligament(PDL)and alveolar bone(AB).Periodontal tissues can be destructed by chronic periodontal disease,which can lead to tooth loss.In support of the treatment for periodontally diseased tooth,various biomaterials have been applied starting as a contact inhibition membrane in the guided tissue regeneration(GTR)that is the current gold standard in dental clinic.Recently,various biomaterials have been prepared in a form of tissue engineering scaffold to facilitate the regeneration of damaged periodontal tissues.From a physical substrate to support healing of a single type of periodontal tissue to multi-phase/bioactive scaffold system to guide an integrated regeneration of periodontium,technologies for scaffold fabrication have emerged in last years.This review covers the recent advancements in development of scaffolds designed for periodontal tissue regeneration and their efficacy tested in vitro and in vivo.Pros and Cons of different biomaterials and design parameters implemented for periodontal tissue regeneration are also discussed,including future perspectives. | Hyun Nyun Woo Young Joon Cho Solaiman Tarafder Chang H.Lee | 2021 | Bioactive Materials2021，6，10： | 6 |
| 4 | 3个不同苹果品种果实品质及对1-MCP的吸附释放规律显示文摘【目的】探讨生产上苹果不同品种贮藏保鲜理论依据和技术。【方法】以3个苹果品种‘旭’、‘嘎拉’、‘蜜脆’为试验材料,用1-甲基环丙烯(1-MCP)进行处理,分析研究了其采收时的品质及对1-MCP的吸附释放特性规律。【结果】‘旭’、‘嘎拉’、‘蜜脆’3个苹果品种硬度、可溶性固形物含量、可滴定酸、固酸比和果肉颜色之间的差异显著(P<0.05),采后1 d内部乙烯含量较低,但3者之间差异显著(P<0.05)。‘旭’、‘嘎拉’、‘蜜脆’果实经过20μL·L-11-MCP于20℃下处理12 h后,内部积累的1-MCP量显著不同,其中‘蜜脆’积累的最多,其次为‘嘎拉’,‘旭’果实内部基本没有积累;而瓶内的1-MCP消耗量没有差别(12 h后,‘旭’、‘嘎拉’和‘蜜脆’瓶内1-MCP消耗量分别为18.3%,17.3%和18.9%)。经过100μL·L-11-MCP于20℃下处理6 h后取出,1-MCP从不同品种果实向外释放的速率和释放量显著不同(P<0.05)。前3 h,‘嘎拉’的释放速率和释放量最大,3 h后,‘蜜脆’的释放速率和释放量最大,‘旭’的释放速率和释放量一直最小。【结论】‘旭’、‘嘎拉’、‘蜜脆’3个不同苹果品种在采后时的品质、内部乙烯含量以及对1-MCP的反应特性不同。经1-MCP处理后,内部积累的1-MCP量显著不同:‘旭’、‘嘎拉’和‘蜜脆’对1-MCP的吸附量(6 h)分别为16.2%、19.8%和7.0%。 | 董晓庆 朱守亮 James H.Lee Donald J.Huber | 2015 | 果树学报2015，32，2： | 5 |
| 5 | Expression of micro RNAs in fibroblast of pterygium显示文摘AIM:To screen microRNAs(miRNAs) and set up target miRNAs in pterygium.METHODS:Primary fibroblasts were isolated from pterygium and Tenon's capsule and cultured.Immunocytochemical analysis and Western blotting were performed to confirm the culture of fibroblasts.In all,1733 miRNAs were screened in the first step by using GeneChip^(?) miRNA3.0 Array.Specific miRNAs involved in the pathogenesis of pterygium were subsequently determined using the following criteria:1) high reproducibility in a repetitive test;2) base log value of >7.0 for both control and pterygial fibroblasts;and 3) log ratio of >1.0 between pterygial fibroblasts and control fibroblasts.RESULTS:Primary screening showed that 887/1733 miRNAs were up-regulated and 846/1733 miRNAs were down-regulated in pterygial fibroblasts compared with those in control fibroblasts.Of the 1733 miRNAs screened,4 miRNAs,namely,miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5p and miRNA-411a-5p,met the above-mentioned criteria.Primary screening showed that these 4 miRNAs were up-regulated in pterygial fibroblasts compared with control fibroblasts and that miRNA-143a-3p had the highest mean ratio compared with the miRNAs in control fibroblasts.CONCLUSION:miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5p and miRNA-411a-5p are up-regulated in pterygial fibroblasts compared with control fibroblasts,suggesting their involvement in the pathogenesis of pterygium. | Joon H.Lee Sun-Ah Jung Young-A Kwon Jea-Lim Chung Ungsoo Samuel Kim | 2016 | International Journal of Ophthalmology(English edition)2016，9，7： | 5 |
| 6 | An overview on development of miniature unmanned rotorcraft systems显示文摘In this article,we attempt to document a technical overview on modern miniature unmanned rotorcraft systems.We first give a brief review on the historical development of the rotorcraft unmanned aerial vehicles(UAVs),and then move on to present a fairly detailed and general overview on the hardware configuration,software integration,aerodynamic modeling and automatic flight control system involved in constructing the unmanned system.The applications of the emerging technology in the military and civilian domains are also highlighted. | Guowei CAI Ben M.CHEN Tong H.LEE | 2010 | Frontiers of Electrical and Electronic Engineering in China2010，5，1： | 4 |
| 7 | Ten‐Day Sequential Therapy as First‐line Treatment for Helicobacter pylori Infection in Korea: A Retrospective Study显示文摘 | Jung H.Kwon Dong H.Lee Byeong J.Song Jung W.Lee Jin J.Kim Young S.Park NayoungKim Sook‐HyangJeong Jin‐WookKim Sang H.Lee Jin H.Hwang Hyun C.Jung In S.Song | 2010 | Helicobacter2010，，2： | 4 |
| 8 | Accuracy of Diagnostic Tests for Helicobacter pylori in Patients with Peptic Ulcer Bleeding显示文摘 | Yoon J.Choi NayoungKim JihwanLim So Y.Jo Cheol M.Shin Hye S.Lee Sang H.Lee Young S.Park Jin‐HyeokHwang Jin‐WookKim Sook‐HyangJeong Dong H.Lee Hyun C.Jung | 2012 | Helicobacter2012，，2： | 4 |
| 9 | New perspectives on probiotics in health and disease显示文摘The gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90%bacteria.Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer,hypertension,hypercholesterolemia,inflammatory bowel diseases,obesity,oral health,etc.have been proposed.What is the real role of probiotics,prebiotics and synbiotics in influencing a healthy microbiota?Both in vitro evidences and in vivo clinical data have supported some of these new health claims,while recent molecular advancement has provided strong indications to support and justify the hypotheses.However,probiotics validity and health claims have continuously been rejected on the basis of“biomarker deficiency”.To battle the increase in health care costs,a preventive approach to medicine with the development of probiotics and prebiotics or symbiotic products is being advanced.This review discusses the potential beneficial effects of probiotics in preventing and treating certain diseases as well as current and future perspectives of probiotic research. | Eric Banan-Mwine Daliri Byong H.Lee | 2015 | Food Science and Human Wellness2015，4，2： | 4 |
| 10 | 韩国中学生中结核分枝杆菌的传播显示文摘背景:利用胸部放射学检查和痰涂片检查手段对中学生进行肺结核病例筛检。目的:调查中学生中结核分枝杆菌的传播情况。设计:对从中学生肺结核病例分离出的结核分枝杆菌进行限制性酶切片段长度多态性(RFLP)图谱分析。结果:筛检发现的中学生病例存在簇状分布现象。在本研究中,一株具有独特RFLP图谱的结核杆菌分离频率最高。该菌株在1995年全国结核病患病率调查中也是最常见的临床分离结核分枝杆菌。该菌株似乎是韩国分布最广的结核杆菌株,编号为K1。经过对RFLP图谱的仔细研究,发现有34株临床分离菌株的RFLP图谱与K1株相似。因此,K1株和K1相关株(占总菌株的18.4%,命名为K系)似构成韩国目前的优势结核分枝杆菌株。结论:筛检发现的中学生病例存在簇状分布现象。K系结核杆菌是临床分离菌株中的最常见型别。 | S.J.Kim G.H.Bai H.Lee H.J.Kim W.J.Lew Y.K.Park Y.Kim 贺晓新 | 2003 | 国际结核病与肺部疾病杂志2003，，1： | 2 |
| 11 | 卵巢癌与饮料的病例对照研究显示文摘卵巢癌是较常见的妇女肿瘤,其生存率较低,因此,控制此病的重点应该是预防。实验室研究显示绿茶具有预防作用,但人群调查则结果不一。茶是我国居民最常用的饮品,如果其预防卵巢癌的作用是确实的,饮茶将是一个较好的预防途径。本研究的目的在于调查常用饮品对卵巢癌的影响,以便为此病的预防提供依据。 | 许凤莲 张敏 Colin W.Binns Andy H.Lee | 2006 | 石河子大学学报(自然科学版)2006，24，4： | 2 |
| 12 | 冠状动脉CT血管成像的心动时相自动选择影像重建研究显示文摘对一种在冠状动脉CT血管成像(CCTA)图像重建时自动选择最小运动心动时相的算法进行评价。我们分析了100例(男49例,女51例)回顾性心电门控CCTA检查的数据。按R—R间期5%间隔重建多个时相图像,2名有经验的观察者主观判断最佳的收缩末期与舒张末期时相。 | B.Ruzsics M.Gebregziabher H.Lee R.L.Brothers T.Allmendinger S.Vogt 王鹤 | 2009 | 国际医学放射学杂志2009，32，5： | 2 |
| 13 | Randomized clinical trial of single‐incision laparoscopic cholecystectomy versus minilaparoscopic cholecystectomy显示文摘 | P.‐C.Lee C.Lo P.‐S.Lai J.‐J.Chang S.‐J.Huang M.‐T.Lin P.‐H.Lee | 2010 | Br J Surg2010，，7： | 2 |
| 14 | Posterior circulation ischemic stroke in Korean population显示文摘 | J.‐H.Lee S.‐J.Han Y.‐H.Yun H.‐C.Choi S.Jung S.‐J.Cho K.‐H.Yu S. M.Lee S.‐H.Hwang H.‐K.Song K. H.Kwon B.‐C.Lee | 2006 | European Journal of Neurology2006，，7： | 2 |
| 15 | The influence of patient position on withdrawal force of thoracic epidural catheters*显示文摘 | W. S.Sim J. W.Choi C. J.Lee F. S.Nahm S. H.Lee B. S.Shin H. S.Cho | 2011 | Anaesthesia2011，，1： | 1 |
| 16 | ORIGINAL ARTICLE: The association of serum vitamin D level with presence of metabolic syndrome and hypertension in middle‐aged Korean subjects显示文摘 | Mee K.Kim MooIl Kang KiWon Oh Hyuk S.Kwon Jin H.Lee Won C.Lee Kun‐HoYoon Ho Y.Son | 2010 | Clinical Endocrinology2010，，3： | 1 |
| 17 | Abnormal cardiovascular reflex tests are predictors of mortality in Type 2 diabetes mellitus显示文摘 | H. S.Chen C. M.Hwu B. I.Kuo S. C.Chiang C. F.Kwok S. H.Lee Y. S.Lee M. J.Weih L. C.Hsiao S. H.Lin L. T.Ho | 2001 | Diabetic Medicine2001，，4： | 1 |
| 18 | Brain Transplantation of Immortalized Human Neural Stem Cells Promotes Functional Recovery in Mouse Intracerebral Hemorrhage Stroke Model显示文摘 | Hong J.Lee Kwang S.Kim Eun J.Kim Hyun B.Choi Kwang H.Lee In H.Park YongKo Sang W.Jeong Seung U.Kim | 2009 | STEM CELLS2009，，： | 1 |
| 19 | Robust cost efficacy of a novel,validated screening test at 12–20 Weeks gestation for the prediction of preterm birth(PTB)at or before 32 Weeks in singletons显示文摘Objective:Preterm birth(PTB)at or before 32 weeks complicates up to 2%of United States(US)births and accounts for 80%of perinatal expenditures in the first year of life.Existing screening tests for PTB performed from 12 weeks to 19 weeks 5 days have receiver operated area under the curve(AUC)indices of<80%and at most<70%.We evaluated FutureBIRTH™,a unique maternal screening test comprised of plasma cell-free RNA for the prediction of PTB≦32 weeks due to spontaneous labor(sPTB)with or without preterm premature rupture of the membranes(PPROM)or early-onset pre-eclampsia before 34 weeks(EOP).FutureBIRTH™is supported by multiple validation studies derived from 12 weeks to 19 weeks 5 days gestation achieving AUCs of 84.2%for sPTB and 94.1%for EOP.Methods:Using the US rates for EOP(0.5%)and sPTB≦32 weeks(1.8%)and adjusting the US pregnancy/neonatal medical costs to US dollars(2017 value),we calculated the cost per 100,000 singletons with or without universal FutureBIRTH™testing before 19 weeks and 6 days using three detection rates and assuming screenpositive women would be treated with and respond to aspirin(assumed 80%efficacy for EOP)and vaginal progesterone(assumed 38%efficacy for sPTB).We also assessed test performance at disease incidence rates below that of the US(down to 0.46%).For considering screening costs,we assumed test costs of$750,and treatment costs of$1000 for patients over 20 weeks gestational age.Results:The identification and treatment of‘at-risk’pregnancies by FutureBIRTH™with existing therapies would reduce direct healthcare costs by up to$95 million per 100,000 births.The projected savings were robust and achievable at each FutureBIRTH™price despite the conservative costs,efficacy,and detection rate assumptions.The incidence of PTB≦32 weeks would decline by 40%–50%with a test cost of$750 and an 80%detection rate.Conclusion:The accurate risk assessment provided by universal FutureBIRTH™screening coupled with existing preventative treatments could lead to a 40%–50%decrease in PTB≦32 weeks due to sPTB and EOP among‘atrisk’pregnancies,covering the cost of screening and treatment while still saving$450-$950 per pregnancy. | Robert H.Lee Carl P.Weiner | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，3： | 1 |
| 20 | Deep‐vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography显示文摘 | F.PIOVELLA C‐J.WANG H.LU K.LEE L. H.LEE W. C.LEE A. G. G.TURPIE A. S.GALLUS A.PLANèS R.PASSERA A.ROUILLON | 2005 | Journal of Thrombosis and Haemostasis2005，，12： | 1 |
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