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| 1 | Unraveling a genetic roadmap for improved taste in the domesticated apple显示文摘Although taste is an important aspect of fruit quality, an understanding of its genetic control remains elusive in apple and other fruit crops. In this study, we conducted genomic sequence analysis of 497 Malus accessions and revealed erosion of genetic diversity caused by apple breeding and possible independent domestication events of dessert and cider apples. Signatures of selection for fruit acidity and size, but not for fruit sugar content, were detected during the processes of both domestication and improvement. Furthermore, we found that single mutations in major genes affecting fruit taste, including Ma1, MdTDT, and MdSOT2, dramatically decrease malate, citrate, and sorbitol accumulation, respectively, and correspond to important domestication events. Interestingly, Ma1 was identified to have pleiotropic effects on both organic acid content and sugar:acid ratio, suggesting that it plays a vital role in determining fruit taste. Fruit taste is unlikely to have been negatively affected by linkage drag associated with selection for larger fruit that resulted from the pyramiding of multiple genes with minor effects on fruit size. Collectively, our study provides new insights into the genetic basis of fruit quality and its evolutionary roadmap during apple domestication, pinpointing several candidate genes for genetic manipulation of fruit taste in apple. | Liao Liao Weihan Zhang Bo Zhang Ting Fang Xiao-Fei Wang Yarning Cai Collins Ogutu Lei Gao Gang Chen Xiaoqing Nie Jinsheng Xu Quanyan Zhang Yiran Ren Jianqiang Yu Chukun Wang Cecilia H.Deng Baiquan Ma Beibei Zheng Chun-Xiang You Da-Gang Hu Richard Espley Kui Lin-Wang Jia-Long Yao Andrew C.Allan Awais Khan Schuyler S.Korban Zhangjun Fei Ray Ming Yu-Jin Hao Li Li Yuepeng Han | 2021 | Molecular Plant2021，14，9： | 5 |
| 2 | Pim‐3 protects against hepatic failure in D‐galactosamine (D‐GalN)‐sensitized rats显示文摘 | L.‐M.Liu J.‐X.Zhang X.‐P.Wang H.‐X.Guo H.Deng J.Luo | 2010 | European Journal of Clinical Investigation2010，，2： | 2 |
| 3 | Diabetes as a risk factor for dementia and mild cognitive impairment: a meta‐analysis of longitudinal studies显示文摘 | G.Cheng C.Huang H.Deng H.Wang | 2012 | Internal Medicine Journal2012，，5： | 2 |
| 4 | Lightning-fast and privacy-preserving outsourced computation in the cloud显示文摘In this paper,we propose a framework for lightning-fast privacy-preserving outsourced computation framework in the cloud,which we refer to as LightCom.Using LightCom,a user can securely achieve the outsource data storage and fast,secure data processing in a single cloud server different from the existing multi-server outsourced computation model.Specifically,we first present a general secure computation framework for LightCom under the cloud server equipped with multiple Trusted Processing Units(TPUs),which face the side-channel attack.Under the LightCom,we design two specified fast processing toolkits,which allow the user to achieve the commonly-used secure integer computation and secure floating-point computation against the side-channel information leakage of TPUs,respectively.Furthermore,our LightCom can also guarantee access pattern protection during the data processing and achieve private user information retrieve after the computation.We prove that the proposed LightCom can successfully achieve the goal of single cloud outsourced data processing to avoid the extra computation server and trusted computation server,and demonstrate the utility and the efficiency of LightCom using simulations. | Ximeng Liu Robert H.Deng Pengfei Wu Yang Yang | 2020 | Cybersecurity2020，3，1： | 1 |
| 5 | Cryptanalysis of a certificateless signcryption scheme in the standard model显示文摘 | Jian Weng Guoxiang Yao Robert H.Deng Min-Rong Chen Xiangxue Li | | 0，，： | 1 |
| 6 | 查看详情显示文摘 | H.Deng C.J.Doonan H.Furukawa R.B.Ferreira J.Towne C.B.Knobler B.Wang and O.M.Yaghi | | 0，，5967： | 1 |
| 7 | Quick 3D Modeling of Machining Environment by Means of On-machine Stereo Vision with Digital Decomposition显示文摘 | X.Tian H.Deng M.Fujishima K.Yamazaki | | 0，，01： | 1 |
| 8 | Preparation of activated carbons from cotton stalk by microwave assisted KOH and K2CO3 activation显示文摘 | H.Deng G.X.Li H.B Yang | | 0，，03： | 1 |
| 9 | Techniques for Hiding Mobile Node's Location Movement Information in Mobile IP显示文摘Mobile IP is an IP layer mobility protocol which allows mobile nodes to remain reachable while moving around in the Internet.In the current IETF Mobile IP specifications,when a mobile node roams, its location movement can be tracked by simply monitoring the IP addresses in IP packets.Recently, the issue of protecting location information in Mobile IP has received increasing attention,especially within the IETF and the 3GPP standard bodies.In this paper we propose a technique for hiding a mobile node’s location movement information from eavesdroppers during route optimization and as well as from its correspondent node during reverse tunneling. The proposed technique is highly efficient and fully compatible with the base Mobile IPv6 operation. | Robert H.DENG | 2007 | China Communications2007，4，1： | 0 |
| 10 | MicroBTC:Efficient,Flexible and Fair Micropayment for Bitcoin Using Hash Chains显示文摘While Bitcoin gains increasing popularity in different payment scenarios,the transaction fees make it difficult to be applied to micropayment.Given the wide applicability of micropayment,it is crucial for all cryptocurrencies including Bitcoin to provide effective support therein.In light of this,a number of low-cost micropayment schemes for Bitcoin have been proposed recently to reduce micropayment costs.Existing schemes,however,suffer from drawbacks such as high computation cost,inflexible payment value,and possibly unfair exchanges.The paper proposes two new micropayment schemes,namely the basic MicroBTC and the advanced MicroBTC,for Bitcoin by integrating the hash chain technique into cryptocurrency transactions.The basic MicroBTC realizes micropayment by exposing hash pre-images on the hash chain one by one,and it can also make arbitrary micropayments by exposing multiple hash pre-images.We further design the advanced MicroBTC to achieve non-interactive refund and efficient hash chain verification.We analyze the complexity and security of the both MicroBTC schemes and implement them using the Bitcoin source code.Extensive experiments were conducted to validate their performance,and the result showed that a micropayment session can be processed within about 18 ms for the basic MicroBTC and 9 ms for the advanced MicroBTC on a laptop.Both schemes enjoy great efficiency in computation and flexibility in micropayments,and they also achieve fairness for both the payer and the payee. | Zhi-Guo Wan Robert H.Deng David Lee Ying Li | 2019 | Journal of Computer Science & Technology2019，34，2： | 0 |
| 11 | Making a good thing better:enhancing password/PIN-based user authentication with smartwatch显示文摘Wearing smartwatches becomes increasingly popular in people’s lives.This paper shows that a smartwatch can help its bearer authenticate to a login system effectively and securely even if the bearer’s password has already been revealed.This idea is motivated by our observation that a sensor-rich smartwatch is capable of tracking the wrist motions of its bearer typing a password or PIN,which can be used as an authentication factor.The major challenge in this research is that a sophisticated attacker may imitate a user’s typing behavior as shown in previous research on keystroke dynamics based user authentication.We address this challenge by applying a set of machine learning and deep learning classifiers on the user’s wrist motion data that are collected from a smartwatch worn by the user when inputting his/her password or PIN.Our solution is user-friendly since it does not require users to perform any additional actions when typing passwords or PINs other than wearing smartwatches.We conduct a user study involving 51 participants so as to evaluate the feasibility and performance of our solution.User study results show that the best classifier is the Bagged Decision Trees,which yields 4.58% FRR and 0.12% FAR on a QWERTY keyboard,and 6.13% FRR and 0.16% FAR on a numeric keypad. | Bing Chang Yingjiu Li Qiongxiao Wang Wen-Tao Zhu Robert H.Deng | 2018 | Cybersecurity2018，1，1： | 0 |
| 12 | Extreme-phenotype GWAS unravels a complex nexus between apple(Malus domestica)red-flesh colour and internal flesh browning显示文摘The genetic link between apple red flesh(RF)coloration and the internal flesh browning disorder(FBD)is a major challenge when breeding high fruit quality RF apple cultivars.A genome-wide association study(GWAS)was conducted in a population of about 900 red-leaved seedlings to identify genomic regions and putative candidate genes using whole genome sequencing of the pools of extreme phenotypes(XP)for the RF colour coverage(using the weighted cortex index(WCI))and FBD.This study identified novel genomic regions contributing to WCI and FBD variation in the red-leaved seedlings.The FBD-associated regions were enriched for genes regulating senescence,heat shock proteins,cytochrome P450,ascorbate metabolism and pectin methyl esterases.Although there were no significant regions in common for WCI and FBD,there were several genes(e.g.MYB85,MYB66,ethylene insensitive 3,DNAJ heat shock protein,WRKY7,and NAC42)enriched commonly between the genomic regions associated with these traits,potentially underpinning the genetic connection between WCI and FBD.Some of the differentially expressed genes between the R6:MdMYB10 and white-fleshed‘control’apples resided within the GWAS hotspot for WCI(e.g.chalcone synthase,UDP-Glycosyl transferase)and FBD(e.g.Rho GTPase activating protein,lipoxygenase 1,phytoene synthase)–validating the XP-GWAS findings.Paralogs of several genes resided in the trait-associated genomic regions,suggesting that whole genome duplication plays an important role in the regulation of these traits.Adverse genetic correlations between WCI and sensory traits were observed,and strategies to develop FBD-free high fruit quality RF cultivars are discussed. | Satish Kumar Cecilia H.Deng Claire Molloy Chris Kirk Blue Plunkett Kui Lin-Wang Andrew Allan Richard Espley | 2022 | Fruit Research2022，2，1： | 0 |
| 13 | The Gillenia trifoliata genome reveals dynamics correlated with growth and reproduction in Rosaceae显示文摘The Rosaceae family has striking phenotypic diversity and high syntenic conservation.Gillenia trifoliata is sister species to the Maleae tribe of apple and~1000 other species.Gillenia has many putative ancestral features,such as herb/sub-shrub habit,dry fruit-bearing and nine base chromosomes.This coalescence of ancestral characters in a phylogenetically important species,positions Gillenia as a‘rosetta stone'for translational science within Rosaceae.We present genomic and phenological resources to facilitate the use of Gillenia for this purpose.The Gillenia genome is the fi rst fully annotated chromosome-level assembly with an ancestral genome complement(x=9),and with it we developed an improved model of the Rosaceae ancestral genome.MADS and NAC gene family analyses revealed genome dynamics correlated with growth and reproduction and we demonstrate how Gillenia can be a negative control for studying fl eshy fruit development in Rosaceae. | Hilary S.Ireland Chen Wu Cecilia H.Deng Elena Hilario Ali Saei Sylvia Erasmuson Ross N.Crowhurst Karine M.David Robert J.Schaffer David Chagn | 2021 | Horticulture Research2021，8，1： | 0 |
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