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| 1 | The wheat MYB-related transcription factor TaMYB72 promotes flowering in rice显示文摘Through large-scale transformation analyses, Ta MYB72 was identified as a flowering time regulator in wheat. Ta MYB72 is a MYB family transcription factor localized to the nucleus. Three Ta MYB72 homologs,Ta MYB72-A, Ta MYB72-B and Ta MYB72-D, cloned from hexaploid wheat were mapped to the short arm of the group 6 chromosomes. Under the long-day conditions,over-expression of the Ta MYB72 in rice shortened the flowering time by approximately 12 d. Expression analyses suggest that Ta MYB72 may function through upregulation of florigen genes Hd3 a and RFT1. | Lichao Zhang Guoxiang Liu Jizeng Jia Guangyao Zhao Chuan Xia Lina Zhang Fu Li Qiang Zhang Chunhao Dong Shuangcheng Gao Longzhi Han Xiuping Guo Xin Zhang Jinxia Wu Xu Liu Xiuying Kong | 2016 | Journal of Integrative Plant Biology2016，58，8： | 8 |
| 2 | Diagnostic value of whole-body MRI with diffusion-weighted sequence for detection of peritoneal metastases in colorectal malignancy显示文摘Objective:To assess the diagnostic accuracy of whole-body MRI using diffusion-weighted sequence(WB-DWI)to determine the peritoneal cancer index(PCI)in correlation with surgical and histopathological findings.Methods:Twenty-seven patients underwent preoperative WB-MRI,followed by cytoreductive surgery for primary tumors of the appendix(n=15),colorectum(n=12),and associated peritoneal disease.A total of 351 regions were retrospectively reviewed.The sensitivity,specificity,and accuracy were calculated at 13 anatomical sites.The WB-DWI PCI and PCI type were compared with surgical and histopathological findings.Results:No statistical difference was found between the WB-DWI PCI and surgical PCI(P=0.574).WB-DWI correctly predicted the PCI type in 24 of 27 patients with high accuracy(88.9%),including 10 of 10 patients with small-volume tumor,12 of 14 with moderate-volume tumor,and 2 of 3 with large-volume tumor.WB-DWI correctly depicted tumors in 163 of 203 regions,with 40false-negative and 23 false-positive regions.The overall sensitivity,specificity,and accuracy of WB-DWI for the detection of peritoneal tumors were 80.3%,84.5%,and 82.1%,respectively.For lesions<0.5 cm in diameter,WB-DWI demonstrated good sensitivity(69.4%).Conclusions:WB-DWI accurately predicted PCI before surgery in patients undergoing evaluation for cytoreductive surgery. | Huan Zhang Weixing Dai Caixia Fu Xu Yan Alto Stemmer Tong Tong Guoxiang Cai | 2018 | Cancer Biology & Medicine2018，15，2： | 3 |
| 3 | Extraction and analysis of saline soil deformation in the Qarhan Salt Lake region (in Qinghai, China) by the sentinel SBAS-InSAR technique显示文摘The instability of saline soil foundation affects the safety of artificial construction,and may cause ground collapse,building destruction and road damage.It is fundamental to reduce the potential engineering geological disasters by exploring the dynamic evolution of saline soil.Most of the previous researches of saline soil were conducted by simulated experiments and traditional geodetic surveying methods.Restricted to the limited sampling points,the spatiotemporal evolution characteristics of saline soil were difficult to find out in a large scale.This paper exploited SBAS-InSAR method to extract the deformation of the Qarhan Salt Lake(in Qinghai,China)section along Qinghai-Tibet railway,based on 119 image data acquired by Sentinel-1A from 2015 to 2020.The results showed that the deformation trends varied frequently in this saline mud flat.Between the adjacent areas with different deformation trends along Qinghai-Tibet railway,discontinuities caused by uplift and subsidence were very obvious.Besides,among the areas with brine exploitation or artificial construction,the maximum subsidence rate reached50 mm/yr,and the maximum cumulative subsidence exceeded 320 mm in the latest 5 years.In the saline mud flat closed to the rivers and lakes,the deformation trend was continuous uplift.Nevertheless,there were obvious seasonal deformation characteristics in those areas far away from the water body.Further analysis found out a sharply subsidence caused by the salt collapsibility appeared in rainy seasons.While an uplift trend induced by the salt swelling or frost heave was remarkable in dry seasons.Subsequently,the relationships were analyzed between the time series deformation and external environmental fac-tors.Furthermore,the deformation mechanism of saline soilin the Qarhan Salt Lake region was inter-preted then.In general,this study provides complete spatiotemporal evolution information of saline soil,and demonstrates the deformation characteristics of saline soil in the Qarhan Salt Lake region suc-cessfully.Related results would contribute to the safety monitoring for large-scale infrastructure con-struction in the saline soil areas. | Wei Xiang Rui Zhang Guoxiang Liu Xiaowen Wang Wenfei Mao Bo Zhang Jialun Cai Jiawen Bao Yin Fu | 2022 | Geodesy and Geodynamics2022，13，2： | 2 |
| 4 | Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma显示文摘Dear Editor,Signet-ring cell carcinoma(SRCC)is a rare subtype of colorectal cancer(CRC)characterized histologically by the accumulation of mucins in the cytoplasm and displacement of nuclei to the cellular periphery,accounting for about 1%CRC(Fig.S1A)(Borger et al.,2007).Compare to common subtypes of CRC,such as adenocarcinoma(AC)and mucinous adenocarcinoma(MAC),SRCC is associated with aggressive behaviors and younger age at presentation(Kang et al.,2005;Sung et al.,2008;Nitsche et al.,2013;Hugen et al.,2014;Inamura et al.,2015).A retrospective analysis of CRC patient's data at Fudan University Shanghai Cancer Center(FUSCC)also indicated a worse overall and disease-free survival of SRCC patients(Fig.S1B and S1C,Table S1). | Yaqi Li Jian Li Renjie Wang Long Zhang Guoxiang Fu Xueying Wang Yebin Wang Chuantao Fang Dandan Zhang Duo Du Xiaoji Ma Mengxue Pan Qiang Guo Xiaoya Xu Xiang Hu Yi Zhou Shaobo Mo Huijun Wang Jianjun Gao Shenglin Huang Yun Liu Sanjun Cai Guoqiang Hua Junjie Peng Fa-Xing Yu | 2020 | Protein & Cell2020，11，4： | 2 |
| 5 | E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis显示文摘Systemic lupus erythematosus(SLE)is a systemic autoimmune disease,and the pathogenesis of SLE has not been fully elucidated.The E3 ubiquitin ligase FBXW7 has been well characterized in cancer as a tumor suppressor that can promote the ubiquitination and subsequent degradation of various oncoproteins;however,the potential role of FBXW7 in autoimmune diseases is unclear.In the present study,we identified that FBXW7 is a crucial exacerbating factor for SLE development and progression in a mouse model induced by 2,6,10,14-tetramethylpentadecane(TMPD).Myeloid cell-specific FBXW7-deficient(Lysm+FBXW7f/f)C57BL/6 mice showed decreased immune complex accumulation,glomerulonephritis,glomerular mesangial cell proliferation,and basemembrane thickness in the kidney.Lysm+FBXW7f/f mice produced fewer anti-Sm/RNP and anti-ANA autoantibodies and showed a decreased MHC II expression in B cells.In Lysm+FBXW7f/f mice,we observed that cell apoptosis was reduced and that fewer CD11b+Ly6Chi inflammatory monocytes were recruited to the peritoneal cavity.Consistently,diffuse pulmonary hemorrhage(DPH)was also decreased in Lysm+FBXW7f/f mice.Mechanistically,we clarified that FBXW7 promoted TMPD-induced cell apoptosis by catalyzing MCL1 degradation through K48-linked ubiquitination.Our work revealed that FBXW7 expression in myeloid cells played a crucial role in TMPD-induced SLE progression in mice,which may provide novel ideas and theoretical support for understanding the pathogenesis of SLE. | Zhenlu Chong Chunjing Bao Jia He Tianxiao Chen Lijia Zhong Gaopeng Li Huanle Li Lutong Fang Yinjing Song Guoxiang Fu Xuyan Yang Lihua Lai Yang Liu Qingqing Wang | 2018 | Cellular & Molecular Immunology2018，15，12： | 2 |
| 6 | Molecular selectivity ol tyrosin-imprinted polymers prepared by seed swelling and suspension polymerization显示文摘 | Zhang Liyong Cheng Guoxiang Fu cong | 2002 | Polymer International2002，51，8： | 1 |
| 7 | Interferometric coherence and seasonal deformation characteristics analysis of saline soil based on Sentinel-1A time series imagery显示文摘Affected by the natural environmental and human activity factors,significant seasonal differences appear on the regional scattering characteristic and ground deformation of saline soil.Interferometric decorrelation due to season replacement limits the conventional multi-temporal interferometric synthetic aperture radar(MT-InSAR)technique and its application in such areas.To extend the monitoring capability in the salt desert area,we select a vast basin of saline soil around Howz-e-Soltan Salt Lake of Iran as the study area and present an improved MTInSAR for experimental research.Based on 131 C-band Sentinel-1 A images collected between October 2014 to July 2020,1896 refined interferograms in total are selected from all interferogram candidates.Interferometric coherence analysis shows that the coherence in the saline soil area has an apparent seasonal variation,and the soil moisture affected by the precipitation may be the main factor that leads to the seasonal variation.Subsequently,the deformation characteristics of saline soil under different environmental conditions and human activity factors are compared and analyzed in detail.Related deformation mechanisms of different saline soil types are initially revealed by combining interferometric coherence,meteorological data,and engineering geological characteristics of saline soil.Related results would provide reference for the large-scale infrastructure construction engineering in similar saline soil areas. | ZHANG Rui XIANG Wei LIU Guoxiang WANG Xiaowen MAO Wenfei FU Yin CAI Jialun ZHANG Bo | 2021 | Journal of Systems Engineering and Electronics2021，32，6： | 1 |
| 8 | Nonlinear calibration and data processing of the solar radio burst显示文摘 | Yihua Yan Chengming Tan Long Xu Huirong Ji Qijun Fu Guoxiang Song | 2002 | Science in China Series A: Mathematics2002，，1： | 1 |
| 9 | Nonlinear calibration and data processing of the solar radio burst显示文摘 | Yihua Yan Chengming Tan Long Xu Huirong Ji Qijun Fu Guoxiang Song | 2002 | Science in China Series A: Mathematics2002，，1： | 1 |
| 10 | Molecular selectivity of tyrosine-imprinted polymers prepared by seed swelling and suspension polymerization显示文摘 | Zhang Liyong Cheng Guoxiang Fu Cong | 2002 | Polymer International2002，51，8： | 1 |
| 11 | Synthesis and characteristics of tyrosine imprinted beads via sus- pension polymerization显示文摘 | ZHANG Liyong CHENG Guoxiang FU Cong | 2003 | Reactive & Functional Polymers2003，56，3： | 1 |
| 12 | Molecular selectivity of tyrosine-imprinted polymers prepared by seed swelling and suspension polymerization显示文摘 | ZHANG Liyong CHENG Guoxiang FU Cong | 2002 | Polymer International2002，51，8： | 1 |
| 13 | Molecular selectivity of tyrosine-imprinted polymers prepared by seed swelling and suspension polymerization显示文摘 | Zhang Liyong Cheng Guoxiang Fu Chong | 2002 | Polym Int2002，51，8： | 1 |
| 14 | Secondary work embrittlement of cold-rolled 05CuPCrNi sheet at low temperature显示文摘Due to the rapid development of China's rail transportation equipment manufacturing industry and related international distribution,important material suppliers such as Baoshan Iron & Steel Co.,Ltd.carries on investigating the stability of material under extremely cold conditions.In this study,mechanical properties and secondary work embrittlement of weathering steel 05 CuPCrNi were tested at low temperature.Compared to the mechanical properties at room temperature,the yield and tensile strength increase slightly with decreasing temperature.However,the variation of elongation is not obvious.The experimental results also show that the secondary work embrittlement transition temperature of 05 CuPCrNi is lower than-60 ℃.These results provide the basis for the use of this train body material in extremely cold regions. | ZHANG Guoxiang LIANG Gaofei FU Yan'an LI Yongcan WANG Xunhong | 2016 | Baosteel Technical Research2016，10，4： | 0 |
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