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| 1 | New molecular method to detect denitrifying anaerobic methane oxidation bacteria from different environmental niches显示文摘The denitrifying anaerobic methane oxidation is an ecologically important process for reducing the potential methane emission into the atmosphere.The responsible bacterium for this process was Candidatus Methylomirabilis oxyfera belonging to the bacterial phylum of NC10.In this study,a new pair of primers targeting all the five groups of NC10 bacteria was designed to amplify NC10 bacteria from different environmental niches.The results showed that the group A was the dominant NC10 phylum bacteria from the sludges and food waste digestate while in paddy soil samples,group A and group B had nearly the same proportion.Our results also indicated that NC10 bacteria could exist in a high p H environment(pH 9.24)from the food waste treatment facility.The Pearson relationship analysis showed that the p H had a significant positive relationship with the NC10 bacterial diversity(p<0.05).The redundancy analysis further revealed that the p H,volatile solid and nitrite nitrogen were the most important factors in shaping the NC10 bacterial structure(p=0.01)based on the variation inflation factors selection and Monte Carlo test(999 times).Results of this study extended the existing molecular tools for studying the NC10 bacterial community structures and provided new information on the ecological distributions of NC10 bacteria. | Sai Xu Wenjing Lu Farooq Mustafa Muhammad Yanting Liu Hanwen Guo Ruihong Meng Hongtao Wang | 2018 | Journal of Environmental Sciences2018，30，3： | 4 |
| 2 | Research progress in protein post-translational modification显示文摘Protein post-translational modification plays an important role in organism. It makes the protein obtain more complicated structures, perfect functions, more accurate regulations and more spe-cific operations. The most common protein post- translational modifications include ubiquitylation, phosphorylation, glycosylation, lipodation, methyla-tion, and acetylation and so on. Ubiquitylation plays an essential role in cellular functions such as cellular differentiation, apoptosis, DNA repair, antigen proc-essing, and stress response. Phosphorylation is re-lated to physiological and pathological processes including cellular signal conduction, nervous activity, muscle contraction and proliferation, development and differentiation of cells. Protein glycosylation is of great importance for many cell processes like im-munoprotection, virus replication, cell growth, and occurrence of inflammation and so on. Lipodation is vital to signal conduction. Histone methylation and acetylation are responsible for transcription regula-tion. In vivo, different post-translational modifications do not occur isolatedly, but influence each other’s function and cooperate with each other. Under-standing what influences the post-translational modi-fications will help to uncover cellular processes and protein network in molecular level and finally direct more precise drug design targeting molecules. Post-translational modification mimics are set to dominate the next wave of protein therapeutics and become powerful medicinal tools in the 21st century. | HU Jia GUO Yanting LI Yanme | 2006 | Chinese Science Bulletin2006，51，6： | 4 |
| 3 | Characterization of Electroless Ni-P Deposits on Surface of AZ91D Magnesium Alloy显示文摘Characterization of electroless nickel deposits on magnesium alloys was investigated by X-ray diffraction(XRD),scanning electron microscope(SEM),energy dispersive spectrometer(EDS)and electrochemical potentiodynamic polarization analysis.The result of XRD showed that the electroless nickel deposits on magnesium alloys were composed mostly of amorphous Ni-P and partially of microcrystalline nickel.The phosphorus content in the Ni-P deposits was 10.8%by the calculation of EDS.SEM micrographs showed that morphology of electroless nickel deposits on magnesium alloys was a typical cellular structure,and the growth of cellular structure was influenced by surface condition of substrate.Zinc layer between substrate and electroless nickel deposits was not found by the results of SEM and EDS,which indicated that the zinc layer on the surface of magnesium alloy was very thin,and the zinc would dissolved while being immersed in electroless nickel plating solution.The thin zinc layer was almost dissolved completely before Ni-P plating.The result of electrochemical potentiodynamic polarization analysis showed that the corrosion potential Ecorr of electroless nickel deposits in 3.5%NaCl solution was about-0.53 V,which was 1 V higher than that of magnesium alloys substrate.And corrosion current density of Ni-P deposits in 3.5%NaCl solution was much smaller than that of magnesium alloys substrate at the same potential value,which indicated that corrosion resistance of electroless Ni-P deposits was excellent.Discoloration time of concentrated nitric acid test for electroless nickel deposits on magnesium alloys was 445 s,which also indicated excellent corrosion resistance. | Li Jiansan Guo Yanting Liu Junquan | 2012 | 稀有金属材料与工程2012，41，S1： | 3 |
| 4 | PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis显示文摘In vitro studies have established the prevalent theory that the mitochondrial kinase PINK1 protects neurodegeneration by removing damaged mitochondria in Parkinson's disease(PD).However,difficulty in detecting endogenous PINK1 protein in rodent brains and cell lines has prevented the rigorous investigation of the in vivo role of PINK1.Here we report that PINK1 kinase form is selectively expressed in the human and monkey brains.CRISPR/Cas9-mediated deficiency of PINK1 causes similar neurodegeneration in the brains of fetal and adult monkeys as well as cultured monkey neurons without affecting mitochondrial protein expression and morphology.Importantly,PINK1 mutations in the primate brain and human cells reduce protein phosphorylation that is important for neuronal function and survival.Our findings suggest that PINK1 kinase activity rather than its mitochondrial function is essential for the neuronal survival in the primate brains and that its kinase dysfunction could be involved in the pathogenesis of PD. | Weili Yang Xiangyu Guo Zhuchi Tu Xiusheng Chen Rui Han Yanting Liu Sen Yan Qi Wang Zhifu Wang Xianxian Zhao Yunpeng Zhang Xin Xiong Huiming Yang Peng Yin Huida Wan Xingxing Chen Jifeng Guo Xiao-Xin Yan Lujian Liao Shihua Li Xiao-Jiang Li | 2022 | Protein & Cell2022，13，1： | 3 |
| 5 | Simultaneous Electrochemical Determination of Ascorbic Acid, Dopamine and Uric Acid Based on Reduced Graphene Oxide-Ag/PANI Modified Glassy Carbon Electrode显示文摘 | GUO Zhuo LUO Xianke LI Yahui LI Dongdi ZHAO Qinai LI Mengmeng MA Chi ZHAO Yanting | 2017 | Chemical Research in Chinese Universities2017，33，3： | 3 |
| 6 | Fundamental mechanisms of cell nucleation in polypropylene foaming with supercritical carbon dioxide—Effects of extensional stresses and crystals显示文摘 | Anson Wong Yanting Guo Chul B. Park | 2013 | The Journal of Supercritical Fluids2013，，： | 1 |
| 7 | A New Species of Genus Fomitiporia显示文摘[Objectives] This study aimed to study the morphological characteristics and molecular phylogeny of a new strain collected from rotten wood of sea buckthorn in Yanbei area of Shanxi Province. [Methods]The specimens were observed with naked eyes. With Melzer,cotton blue and 5% KOH as floating carriers,the slices were prepared,which were observed under a microscope. The ITS sequence of the new strain was compared with those of the 20 kinds of reported fungi to construct molecular phylogenetic tree based on ITS. [Results] The new strain has horseshoe-shaped basidiocarp and pileus shape and has no stipe. Sometimes,it grows procumbently and scrolled backward. The mycelial system is monomitic. The skeletal hyphae showed a negative reaction in the Melzer reagent and cotton blue reagent. The basidiospores are subglobose or spherical and colorless with thick wall. The results of molecular phylogenetic analysis showed that the new strain had a close relationship with Fomitiporia spp. and was clustered into the same branch with them. It formed an independent sub-branch in the phylogenetic tree. [Conclusions] The new strain was identified as a new species of Fomitiporia,named as Fomitiporia yanbeiensis S. Guo & L. Zhou( Gen Bank: KT861405,Fungal name: FN570360). | Shang GUO Lin ZHOU Jingru ZHANG Lina XU Yanting LI Xiaojie NAN Xiaogang LIU | 2018 | Medicinal Plant2018，9，2： | 1 |
| 8 | MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells显示文摘 | Hongping Xia Yanting Qi Samuel S. Ng Xiaona Chen Shen Chen Marong Fang Dan Li Yu Zhao Ruiguang Ge Guo Li Yangchao Chen Ming-Liang He Hsiang-fu Kung Lihui Lai Marie C. Lin | 2009 | Biochemical and Biophysical Research Communications2009，，2： | 1 |
| 9 | microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs显示文摘 | Hongping Xia Yanting Qi Samuel S. Ng Xiaona Chen Dan Li Shen Chen Ruiguang Ge Songshan Jiang Guo Li Yangchao Chen Ming-Liang He Hsiang-fu Kung Lihui Lai Marie C. Lin | 2008 | Brain Research2008，，： | 1 |
| 10 | Dissolved organic matter accelerates microbial degradation of 17 alpha-ethinylestradiol in the presence of iron mineral显示文摘Dissolved organic matter(DOM)and iron minerals widely existing in the natural aquatic environment can mediate the migration and transformation of organic pollutants.However,the mechanism of interaction between DOM and iron minerals in the microbial degradation of pollutants deserves further investigation.In this study,the mechanism of 17 alphaethinylestradiol(EE2)biodegradation mediated by humic acid(HA)and three kinds of iron minerals(goethite,magnetite,and pyrite)was investigated.The results found that HA and iron minerals significantly accelerated the biodegradation process of EE2,and the highest degradation efficiency of EE2(48%)was observed in the HA-mediated microbial system with pyrite under aerobic conditions.Furthermore,it had been demonstrated that hydroxyl radicals(HO·)was the main active substance responsible for the microbial degradation of EE2.HO·is primarily generated through the reaction between hydrogen peroxide secreted by microorganisms and Fe(II),with aerobic conditions being more conducive.The presence of iron minerals and HA could change the microbial communities in the EE2 biodegradation system.These findings provide new information for exploring the migration and transformation of pollutants by microorganisms in iron-rich environments. | Huan He Min Shi Xiaoxia Yang Juhong Zhan Yanting Lin Ziwei Guo Zhicheng Liao Chaochao Lai Xiaomin Ren Bin Huang Xuejun Pan | 2024 | Journal of Environmental Sciences2024，，5： | 0 |
| 11 | GTPase ROP6 negatively modulates phosphate deficiency through inhibition of PHT1;1 and PHT1;4 in Arabidopsis thaliana显示文摘Phosphorus,an essential macroelement for plant growth and development,is a major limiting factor for sustainable crop yield.The Rho of plant(ROP)GTPase is involved in regulating multiple signal transduction processes in plants,but potentially including the phosphate deficiency signaling pathway remains unknown.Here,we identified that the rop6 mutant exhibited a dramatic tolerant phenotype under Pi-deficient conditions,with higher phosphate accumulation and lower anthocyanin content.In contrast,the rop6 mutant was more sensitive to arsenate(As(V))toxicity,the analog of Pi.Immunoblot analysis displayed that the ROP6 protein was rapidly degraded through ubiquitin/26S proteasome pathway under Pi-deficient conditions.In addition,pull-down assay using GST-RIC1 demonstrated that the ROP6 activity was decreased obviously under Pi-deficient conditions.Strikingly,protein-protein interaction and two-voltage clamping assays demonstrated that ROP6 physically interacted with and inhibited the key phosphate uptake transporters PHT1;1 and PHT1;4 in vitro and in vivo.Moreover,genetic analysis showed that ROP6 functioned upstream of PHT1;1 and PHT1;4.Thus,we conclude that GTPase ROP6 modulates the uptake of phosphate by inhibiting the activities of PHT1;1 and PHT1;4 in Arabidopsis. | Huiling Gao Tian Wang Yanting Zhang Lili Li Chuanqing Wang Shiyuan Guo Tianqi Zhang Cun Wang | 2021 | Journal of Integrative Plant Biology2021，63，10： | 0 |
| 12 | The use of an oxidative stress scoring systemin prognostic prediction for kidney renal clear cell carcinoma显示文摘Dear editor,Oxidative stress induced by reactive oxygen species(ROS)production plays a key role in tumor initiation and progression[1,2].Emerging evidence has shown that oxidative stress-related genes could be used as biomarkers for predicting the progression and prognosis of malignant tumors[3].Our previous study showed that the expression and genotypes of oxidative stress-related genes could be used for predicting the chemosensitivity and clinical outcomes of biliary tract cancer patients[4]. | Xianjin Wang Huan Xu Miaomiao Guo Yanting Shen Peizhang Li Zhong Wang Ming Zhan | 2021 | Cancer Communications2021，41，4： | 0 |
| 13 | Retrieval of Winter Wheat Canopy Carotenoid Content with Ground-and Airborne-Based Hyperspectral Data显示文摘Accurate assessment of canopy carotenoid content(CC_(x+c)C)in crops is central to monitor physiological conditions in plants and vegetation stress,and consequently supporting agronomic decisions.However,due to the overlap of absorption peaks of carotenoid(C_(x+c))and chlorophyll(C_(a+b)),accurate estimation of carotenoid using reflectance where carotenoid absorb is challenging.The objective of present study was to assess CC_(x+c)C in winter wheat(Triticum aestivum L.)with ground-and aircraft-based hyperspectral measurements in the visible and near-infrared spectrum.In-situ hyperspectral reflectance were measured and airborne hyperspectral data were acquired during major growth stages of winter wheat in five consecutive field experiments.At the canopy level,a remarkable linear relationship(R^(2)=0.95,p<0.001)existed between C_(x+c) and Ca+b,and correlation between CC_(x+c)C and wavelengths within 400 to 1000 nm range indicated that CC_(x+c)C could be estimated using reflectance ranging from visible to near-infrared wavebands.Results of Cx+c assessment based on chlorophyll and carotenoid indices showed that red edge chlorophyll index(CI red edge)performed with the highest accuracy(R^(2)=0.77,RMSE=22.27μg/cm^(2),MAE=4.97μg/cm^(2)).Applying partial least square regression(PLSR)in CC_(x+c)C retrieval emphasized the significance of reflectance within 700 to 750 nm range in CC_(x+c)C assessment.Based on CI red edge index,use of airborne hyperspectral imagery achieved satisfactory results in mapping the spatial distribution of CC_(x+c)C.This study demonstrates that it is feasible to accurately assess CC_(x+c)C in winter wheat with red edge chlorophyll index provided that C_(x+c) correlated well with C_(a+b) at the canopy scale.it is therefore a promising method for CC_(x+c)C retrieval at regional scale from aerial hyperspectral imagery. | Ting Cui Xianfeng Zhou Yufeng Huang Yanting Guo Yunrui Lin Leyi Song Jingcheng Zhang | 2023 | Phyton-International Journal of Experimental Botany2023，92，9： | 0 |
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