|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Celiac disease:Prevalence,diagnosis,pathogenesis and treatment显示文摘Celiac disease(CD) is one of the most common diseases,resulting from both environmental(gluten) and genetic factors [human leukocyte antigen(HLA) and nonHLA genes].The prevalence of CD has been estimated to approximate 0.5%-1% in different parts of the world.However,the population with diabetes,autoimmune disorder or relatives of CD individuals have even higher risk for the development of CD,at least in part,because of shared HLA typing.Gliadin gains access to the basal surface of the epithelium,and interact directly with the immune system,via both trans-and para-cellular routes.From a diagnostic perspective,symptoms may be viewed as either 'typical' or 'atypical'.In both positive serological screening results suggestive of CD,should lead to small bowel biopsy followed by a favourable clinical and serological response to the gluten-free diet(GFD) to confirm the diagnosis.Positive anti-tissue transglutaminase antibody or antiendomysial antibody during the clinical course helps to confirm the diagnosis of CD because of their over 99% specificities when small bowel villous atrophy is present on biopsy.Currently,the only treatment available for CD individuals is a strict life-long GFD.A greater understanding of the pathogenesis of CD allows alternative future CD treatments to hydrolyse toxic gliadin peptide,prevent toxic gliadin peptide absorption,blockage of selective deamidation of specific glutamine residues by tissue,restore immune tolerance towards gluten,modulation of immune response to dietary gliadin,and restoration of intestinal architecture. | Naiyana Gujral Hugh J Freeman Alan BR Thomson | 2012 | World Journal of Gastroenterology2012，18，42： | 19 |
| 2 | A RANDOMIZED TRIAL COMPARING TRANSURETHRAL RESECTION OF THE PROSTATE, LASER THERAPY AND CONSERVATIVE TREATMENT OF MEN WITH SYMPTOMS ASSOCIATED WITH BENIGN PROSTATIC ENLARGEMENT: THE CLasP STUDY显示文摘 | JENNY L. DONOVAN TIM J. PETERS DAVID E. NEAL SARA T. BROOKES SANDEEP GUJRAL K. NINAN CHACKO MARK WRIGHT L. GAIL KENNEDY PAUL ABRAMS | 2000 | The Journal of Urology2000，，1： | 3 |
| 3 | Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: Apoptosis or necrosis?显示文摘 | Jaspreet S. Gujral Thomas J. Bucci Anwar Farhood Hartmut Jaeschke | 2001 | Hepatology2001，，2： | 2 |
| 4 | Sonographic diagnosis of Bouveret's syndrome 显示文摘 | Venkatesh S K Thyagarajan M S Gujral R B | 2003 | J Clin Ultrasound2003，31，： | 2 |
| 5 | Effect of sand roasting and microwave cooking on antioxidant activity of barley显示文摘 | Paras Sharma Hardeep Singh Gujral | 2010 | Food Research International2010，，1： | 2 |
| 6 | Effect of additives on dough development, gaseous release and bread making properties 显示文摘 | Hardeep Singh Gujral Narpinder Singh | 1999 | Food Research International1999，32，： | 1 |
| 7 | Whole-genome se- quencing in autism identifies hot spots for de novo germline mutation显示文摘 | Michaelson JJ Shi Y Gujral M | 2012 | Cell2012，151，7： | 1 |
| 8 | Serum albumin is predictive of 30-day survival after percutaneous endoscopic gastrostomy显示文摘 | Friedenberg F Jensen G Gujral N | 1997 | JPEN1997，21，： | 1 |
| 9 | Mode of cell death after acetaminophen overdose in mice:apoptosis of oncotic necrosis?显示文摘 | Gujral JS Knight TR Farhood A | 2002 | Toxicol Sci2002，67，2： | 1 |
| 10 | Effect of accelerated ag- ing on the physicochemical and textural prop- erties of brown and milled rice 显示文摘 | Gujral H S Kumar V | 2003 | Journal of Food Engineering2003，，59： | 1 |
| 11 | MR imaging and angiography in tuberculous meningitis显示文摘 | R. K. Gupta S. Gupta D. Singh B. Sharma A. Kohli R. B. Gujral | 1994 | Neuroradiology1994，，2： | 1 |
| 12 | Texture Profile Analysis 显示文摘 | Gujral H S Kaur A Singh N | 1978 | food technol1978，32，7： | 1 |
| 13 | Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosisor necrosis? 显示文摘 | GUJRAL J S BUCCI T J FARHOOD A | 2001 | Hepatology2001，33，2： | 1 |
| 14 | Effect of sand roasting and microwavecooking on antioxidant activity of barley显示文摘 | Sharma P Gujral H S | | 0，，： | 1 |
| 15 | Dermatopathic lymphadeni- tis in HIV 显示文摘 | Vanisri HR Nandini NM Gujral S | 2009 | Indian J Sex Transm Dis2009，30，： | 1 |
| 16 | Hyperthyroidism :a secondary cause of isolated systolic hypertension 显示文摘 | Prisant LM Gujral JS Mulloy AL | 2006 | J Clin Hypertens (Greenwich)2006，8，8： | 1 |
| 17 | Mechanism of cell death during warm hepatic ischemia - reperfusion in rats : apoptosis or necrosis 显示文摘 | Gujral JS Bucci TJ Farhood A | 2001 | Hepatology2001，33，2： | 1 |
| 18 | Effect of sand roasting and microwave cooking on antioxidant activity of barley显示文摘 | Sharma P Gujral H S | 2011 | Food Research International2011，44，1： | 1 |
| 19 | Effect of cyclodextrinase on dough rheology and bread quality from rice flour显示文摘 | GUJRAL H S GUARDIOLA I CARBONELL J V J | 2003 | Agric Food Chem2003，51，： | 1 |
| 20 | Burkitt' s lymphoma with leptomeningeal metastasis: demonstration by FDG-PET and MRI显示文摘 | Sainia NS Gujral GS Tripathi M | 2008 | Eur J Radiol Extra2008，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员