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| 1 | Molecular targeting agents associated with transarterial chemoembolization or radiofrequency ablation in hepatocarcinoma treatment显示文摘Hepatocellular carcinoma(HCC)is the fifth most common cause of cancer in the world.According to Barcelona Clinic Liver Cancer modified criteria,patients with early stage disease are candidate to radiofrequency ablation(RFA),while patients with intermediate stage HCC are usually treated by transarterial chemoembolization(TACE).TACE and RFA induce a transient devascularisation effect followed by strong neoangiogenic stimulus.In fact,after these procedures,it has been demonstrated an up-regulation of pro-angiogenic and growth factors such as vascular endothelial growth factor-A,which might contribute to accelerated progression in patients with incomplete response.Several studies have demonstrated that MAP-kinase and AKT pathways,in addition to neo-angiogenesis,have an important role in the development of HCC.In advanced HCC,anti-angiogenic therapy and tyrosine kinases inhibitors showed potential clinical benefit.Actually,a number of clinical studies are ongoing testing these agents in combination with TACE or RFA.In this paper,we have reviewed the most recent preclinical and clinical results of such trials. | Girolamo Ranieri Ilaria Marech Vito Lorusso Veronica Goffredo Angelo Paradiso Domenico Ribatti Cosmo Damiano Gadaleta | 2014 | World Journal of Gastroenterology2014，20，2： | 14 |
| 2 | A Reporting System on Patients Evaluated for Coronary Artery Disease显示文摘 | W. GERALD AUSTEN JESSE E. EDWARDS ROBERT L. FRYE GOFFREDO G. GENSINI VINCENT L. GOTT LAWRENCE S. C. GRIFFITH DWIGHT C. MCGOON MARVIN L. MURPHY BENSON B. ROE | 1975 | Circulation1975，，4： | 2 |
| 3 | Malignant pheochromocytoma and paraganglioma:A population level analysis of long-term survival over two decades显示文摘 | Goffredo P Sosa JA Roman SA | 2013 | Journal of Surgical Oncology2013，107，6： | 1 |
| 4 | A more meaningful scoring system for determining the severity of coronary heart disease显示文摘 | Gensini M D Goffredo G | 1983 | Am J Cardiol1983，51，3： | 1 |
| 5 | Effects of atrovastatin on arterial endothelial function in coronary bypass surgery显示文摘 | CHELLO M GOFFREDO C PATTI G | 2005 | Eur J Cardiothorac Surg2005，28，6： | 1 |
| 6 | Expres- sion analysis in response to low temperature stress in blood oranges: implication of the flavonoid biosynthetic pathway 显示文摘 | Crifo Tiziana Puglisi Ivana Petrone Goffredo | 2011 | Gene2011，480，12： | 1 |
| 7 | Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study显示文摘 | Martina Goffredo Sonia Caprio Ariel E. Feldstein Ebe D’Adamo Melissa M. Shaw Bridget Pierpont Mary Savoye Hongyu Zhao Allen E. Bale Nicola Santoro | 2016 | Hepatology2016，，1： | 1 |
| 8 | Prevention of cytosolic IAPsdegradation:a potential pharmacological target in Huntington's Disease显示文摘 | Goffredo D Rigamonti D Zuccato C | 2005 | Pharmacol Res2005，52，2： | 1 |
| 9 | Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease显示文摘 | Goffredo D Rigamonti D Zuccato C | 2005 | Pharmacol Res2005，52，2： | 1 |
| 10 | Patterns of Use and Short-Term Outcomes of Minimally Invasive Surgery for Malignant Pheochromocytoma: A Population- Level Study显示文摘 | GOFFREDO P ADAM MA THOMAS SM | 2015 | World journal of surgery2015，39，8： | 1 |
| 11 | Variation in biometry and population density of solitarycorals with solar radiation and sea surface temperature in the Mediterranean Sea 显示文摘 | GOFFREDO S CAROSELLI E PIGNOTTI E | 2007 | Mar Biol2007，152，2： | 1 |
| 12 | Prevention of cytosolic lAPs degradation: a potential pharmacological target in Huntingtons Disease显示文摘 | Goffredo D Rigamonti D Zuccato C | 2005 | Pharmacol Res2005，52，2： | 1 |
| 13 | The emergence of Schmallenberg virus across Culicoides communities and ecosys- tems in Europe 显示文摘 | Balenghien T Pages N Goffredo M | 2014 | Prev Vet Med2014，116，4： | 1 |
| 14 | Have 2006 ATA practice guidelines affected the treatment of differentiated thyroid cancer in the United States? 显示文摘 | GOFFREDO P ROMAN S A SOSA J A | 2013 | Thyroid2013，24，3： | 1 |
| 15 | Schmallenberg virus in Italy: a retrospective survey in Culicoides stored during the blue- tongue Italian surveillance program 显示文摘 | Goffredo M Monaco F Capelli G | 2013 | Prey Vet Med2013，111，34： | 1 |
| 16 | Effects of atorvasta- fin'on arterial endothehal function in coronary by- pass surgery显示文摘 | Chello M Goffredo C Patti G | 2005 | Eur J Cardlothorac Surg2005，28，： | 1 |
| 17 | Effects of atorvastatin on arterial endothelial function in coronary bypass surgery 显示文摘 | Chello M Goffredo C Patti G | 2005 | Eur J Cardiothorac Surg2005，28，6： | 1 |
| 18 | Effects of atorvastatin on arterial endothelial function in coronary bypass surgery显示文摘 | Chello M Goffredo C Patti G | 2005 | Eur J Caridothorac Surg2005，28，： | 1 |
| 19 | Differentiating embryonic stem-derived neural stem cells show a maturation-dependent pat- tern of voltage-gated sodium current expression and graded action potentials显示文摘 | Biella G Di Febo F Goffredo D | 2007 | Neuroscience2007，149，1： | 1 |
| 20 | Specific Spectral bands for different land cover contexts toimprove the efficiency of remote sensing archaeologicalprospection:The Arpi case study显示文摘 | BASSANI C CAVALLI R Mi GOFFREDO R | 2009 | Journal of CulturalHeritage2009，10，1： | 1 |
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