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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | New developments in acoustic and electroacoustic spectroscopy for characterizing concentrated dispersions 显示文摘 | DUKHIN A S GOETZ P J | 2001 | Colloids and Surfaces: A Physicochemical and Engineering Aspects2001，192，3： | 1 |
| 3 | Method for improving extended Kalman filter performance for angle-only passive ranging 显示文摘 | Guerci J R Goetz R A DiModica J | 1994 | IEEE Transactions on Aerospace and Electronic Systems (S0018-9251)1994，30，4： | 1 |
| 4 | Bonding of silicon wafers for silicon on insulator 显示文摘 | MASZARA W P GOETZ G CAVIGLIA A | 1988 | Appl Phys1988，64，15： | 1 |
| 5 | Integratedpowertrain control of gearshifts on twin clutchtransmissions显示文摘 | Goetz M Levesley M C Crolla D A | 2004 | Transmission and DrivelineSymposium2004，，1： | 1 |
| 6 | Association with prior fluoroquinolone therapy of widespread ciprofloxacin resistance among gram-negative isolates in a veterans affairs medical center显示文摘 | MUDER R R BRENNEN C GOETZ M A | 1999 | Antimicrob Agents Chemother1999，35，： | 1 |
| 7 | Air passenger transportation and growth in the US urban system 1950- 1987 显示文摘 | GOETZ A R | 1992 | Growth and Change1992，23，： | 1 |
| 8 | Induction of male sterility in plants by metabolic engineering of the carbohydrate supply显示文摘 | Goetz M Godt D Gvivarch A | 2001 | Proc Natl Acad Sci USA2001，98，11： | 1 |
| 9 | Geological remote sensing显示文摘 | GOETZ A F H ROWAN L C | 1981 | Science1981，211，： | 1 |
| 10 | Developments in combination chemotherapy for colorectal cancer 显示文摘 | Goetz MP Grothey A | 2004 | Expert Rev Anticancer Ther2004，4，4： | 1 |
| 11 | Discrimination of hydrothermally altered rocks and unaltered rocks in visible and near infrared multi- spectral images显示文摘 | ROWAN L C GOETZ A F H ASHLEY R P | 1977 | Geophysics1977，42，3： | 1 |
| 12 | Occupational asthma in a seafood restaurant worker: cross-reactivity of shrimp and scallops 显示文摘 | Goetz D W Whisman B A | 2000 | Ann Allergy Asthma Immunol2000，85，6： | 1 |
| 13 | Subsidence resulting from simulated postoperative neck ovements:an in vitro investigation with a new cervical fusion cage显示文摘 | Wilke HJ Kettler A Goetz C | | 0，，21： | 1 |
| 14 | Theory of Mind and Psychoses 显示文摘 | Doody G A Goetz M Johnstone E C | 1998 | Psychological Medicine1998，28，： | 1 |
| 15 | Subsidence resulting from simula- ted postoperative neck movements:an in vitro investigation with a new cervical fusion cage 显示文摘 | Wilke H J Kettler A Goetz C | 2000 | Spine2000，21，： | 1 |
| 16 | Predictors of gastric emptying in Parkinson' s disease 显示文摘 | Goetze O Nikodem A B Wiezcorek J | 2006 | Neurogastro- enlerol Motil2006，18，5： | 1 |
| 17 | Transport geography: Reflecting on a subdis- cipline and identifying future research trajectories 显示文摘 | Goetz A R | 2006 | Journal of Transport Geography2006，14，3： | 1 |
| 18 | Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co expressed receptor polypeptide显示文摘 | Tseng GJ Kost T Goetz A | 1995 | Bri J Pharmacol1995，115，： | 1 |
| 19 | Possible near-IR channels for remote sensing precipitable water vapor from geostationary satellite platforms显示文摘 | Gao B C Goetz A F Westwater E R | 1993 | J Appl Meteor1993，32，12： | 1 |
| 20 | Acoustic spectroscopy for concentrated polydisperse colloids with high density contrast 显示文摘 | DUKHIN A S GOETZ P J | 1996 | Langmuir1996，12，21： | 1 |
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