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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | 肾动脉内支架成形术的临床应用显示文摘目的:对肾动脉阻塞性病变采用Palmaz内支架进行治疗,并对其临床远期疗效进行前瞻性、非随机研究分析。材料与方法:7例(26%)为经皮肾动脉气囊成形术(PTRA)治疗失败者,13例(48%)为PTRA后病变再狭窄,4例(15%)为PTRA后出现并发症,3例(11%)为肾动脉开口处狭窄直接作内支架治疗。共有4枚Palmaz内支架、5枚Palmaz-Schats节段性内支架及18枚Palmaz中号内支架被用于本组病例,内支架透视导向下用气囊导管及8F导引鞘释放到靶血管段。结果:技术成功率为100%(残余狭窄<30%),未发生严重并发症,病变两端平均压差从6.8±1.5kPa(1kPa=7.5mmHg)降至0kPa(P<0.05),随访结果(3~32个月,平均10±6个月)显示4例治愈,20例缓解,总有效率89%,平均收缩压从术前24.8±3.0kPa降至18.9±2.0kPa,舒张压从14.7±1.3kPa降至11.3±1.5kPa(P<0.05),6例肾功能衰竭病人中有2例术后肾功能改善,另4例稳定不变,2例分别于术后3、18个月出现病变内再狭窄,但未出现临床症状,病变两端压力差改变不显著。结论:常规PTRA? | 杨建勇 Thomas Roeren Goetz M Richter Goetz W Kaufmann | 1996 | 中华放射学杂志1996，30，5： | 8 |
| 3 | Integratedpowertrain control of gearshifts on twin clutchtransmissions显示文摘 | Goetz M Levesley M C Crolla D A | 2004 | Transmission and DrivelineSymposium2004，，1： | 1 |
| 4 | Association with prior fluoroquinolone therapy of widespread ciprofloxacin resistance among gram-negative isolates in a veterans affairs medical center显示文摘 | MUDER R R BRENNEN C GOETZ M A | 1999 | Antimicrob Agents Chemother1999，35，： | 1 |
| 5 | Tracheostomy with invasive ventilation for ALS patients: Neurologists' roles in the US and Japan显示文摘 | Rabkin J Ogino M Goetz R | 2013 | Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration2013，14，2： | 1 |
| 6 | Pain in idiopathic Parkinson's disease显示文摘 | Goetz CG Tanner CM Levy M | 1986 | Mov Disord1986，1，： | 1 |
| 7 | Molecular imaging in endoscopy 显示文摘 | Hoetker M S Goetz M | 2013 | United European Gastroenterol J2013，1，2： | 1 |
| 8 | Induction of male sterility in plants by metabolic engineering of the carbohydrate supply显示文摘 | Goetz M Godt D Gvivarch A | 2001 | Proc Natl Acad Sci USA2001，98，11： | 1 |
| 9 | ATM-dependent IGF-1induction regulates secretory clusterin expression after DNA damage and in genetic instability显示文摘 | Goetz E M Shankar B Zou Y | 2011 | Oncogene2011，30，35： | 1 |
| 10 | Theory of Mind and Psychoses 显示文摘 | Doody G A Goetz M Johnstone E C | 1998 | Psychological Medicine1998，28，： | 1 |
| 11 | Binary and ternary anode catalyst formulations including the elements W, Sn and Mo for PEMFCs operated on methanol or reformate gas显示文摘 | Goetz M Wendt H | 1998 | Electrochimica Acta1998，43，： | 1 |
| 12 | Synthesis and characterization of carbon-supported Pt-Ru-WOx catalysts by spectroscopic and diffraction methods 显示文摘 | Roth C Goetz M Fuess H | 2001 | Journal of Applied Electrochemistry2001，31，： | 1 |
| 13 | Chronic diarrhea as a result of intestinal microsposidiosis in a liver transplant recipient显示文摘 | Goetz M Eichenlaub S Pape GR | 2001 | Transplantation2001，71，2： | 1 |
| 14 | A method for a more complete in vitro Parkinson's model:slice culture bioassay for modeling maintenance and repair of the nigrostriatal circuit显示文摘 | Kearns S M Scheffler B Goetz AK | 2006 | J Neurosci Methods2006，157，1： | 1 |
| 15 | Increased cardiac BNP expression associated with myocardial ischemia显示文摘 | GOETZE J P CHRISTOFFERSEN C PERKO M | 2003 | FASEB J2003，17，： | 1 |
| 16 | Confocal laser endomicroscopy显示文摘 | Kiesslich R Goetz M Vieth M | 2005 | Gastrointest Endosc Clin N Am2005，15，4： | 1 |
| 17 | Impact of American Society of Clinical Oncology/ College of American Pathologists guideline recommendations on HER2 interpretation in breast cancer显示文摘 | SHAH S S KETTERLING R P GOETZ M P | 2010 | Hum Pathol2010，41，1： | 1 |
| 18 | Increased cardiac BNP ex- pression associated with myocardial isehemia显示文摘 | J Goetze C Christoffersen M Perko | 2003 | Faseb J2003，17，9： | 1 |
| 19 | In vivo histology of Barrett' s esophagus and associated neoplasia by confocal laser endomicroscopy 显示文摘 | Kiesslich R Gossner L Goetz M | 2006 | Clin Gastroenterol Hepatol2006，4，8： | 1 |
| 20 | Workability of aga ma titanium aluminide alloy during equal channel angular extru- sion 显示文摘 | Semiatin S L Segal V M Goetz R L | 1995 | Scripta Materialia1995，33，4： | 1 |
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